*Grapefruit seed extract

Grapefruit can have a number of interactions with certain drugs, increasing the potency of many compounds, including warfarin ( ... Thus, it is this effect that increases the rate of absorption of several drugs. There are concerns about the safety of ...

*Bergamottin

"Grapefruit juice-drug interactions". Br J Clin Pharmacol. 46 (2): 101-110. doi:10.1046/j.1365-2125.1998.00764.x. PMC 1873672 . ... or synthetic analogs may be developed as drugs that are targeted to increase the oral bioavailability of other drugs. Drugs ... This prevents oxidative metabolism of certain drugs by the enzyme, resulting in an elevated concentration of drug in the ... Under normal circumstances, the grapefruit juice effect is considered to be a negative interaction, and patients are often ...

*Herb-drug interactions

Most herb-drug interactions are moderate in severity. The most commonly implicated conventional drugs in herb-drug interactions ... Herb-drug interactions are drug interactions that occur between herbal medicines and conventional drugs. These types of ... Examples of herb-drug interactions include, but are not limited to: St. John's wort affects the clearance of numerous drugs, ... Some such interactions are clinically significant, although most herbal remedies are not associated with drug interactions ...

*Grapefruit-drug interactions

The interaction between citrus and medication depends on the individual drug, and not the class of the drug. Drugs that ... "Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential toxicity for certain drugs". ... The interaction is greatest when the juice is ingested with the drug or up to 4 hours before the drug.[better source needed][ ... Drugs that are metabolized by these enzymes may have interactions with citrus chemicals. When drugs are taken orally, they ...

*Drug interaction

... drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs ... Drug interactions tool for multiple and non-drug interactions. Data from over 2500 drug labels and 5000 trials, 10000 active ... Multi-Drug Interaction Checker by Medscape [6] Drug Interactions Checker by Drugs.com [7] The term effective dose is generally ... are taking medication and or supplements that put them at risk of a major drug interaction. Potential drug-drug interactions ...

*Alpha-1 blocker

"Drug Interactions Indiana University, School of Medicine, Department of Medicine". medicine.iupui.edu. Retrieved 2017-09-28. ... Bailey, David G; Malcolm, J; Arnold, O; David Spence, J (August 1998). "Grapefruit juice-drug interactions". British Journal of ... Drugs that inhibit CYP3A4 for example itraconazol, ketoconazol and ritonavir can increase drug exposure for tamsulosin, ... On the other hand, the drug (a) elevates risk for floppy iris syndrome, and (b) might show adverse drug reactions (ADRs) ...

*Rifampicin

Stockley, Ivan H. "Anticoagulant Drug Interactions." Drug Interactions. 3rd ed. Boston: Blackwell Scientific Publications, 1994 ... This may also be used to monitor effective absorption of the drug (if drug color is not seen in the urine, the patient may wish ... Early detection of such multi-drug or extensively drug-resistant tuberculosis is critical in improving patient outcomes by ... which can be used as a marker for whether or not a dose of the drug has been effectively absorbed. Distribution of the drug is ...

*Mebendazole

"Drug Interactions". Medicine chest. Archived from the original on 2007-02-06. Retrieved 2008-05-06. Luder PJ, Siffert B, ... Long-term follow-up of plasma mebendazole levels and drug interactions". European journal of clinical pharmacology. 31 (4): 443 ... High-Cost Generic Drugs - Implications for Patients and Policymakers Jonathan D. Alpern, M.D., William M. Stauffer, M.D., M.S.P ... Other drugs are used to treat worm infections outside the digestive tract, as mebendazole is poorly absorbed into the ...

*Dipyridamole

Stockley's Drug Interactions. The Pharmaceutical Press. ISBN 0-85369-424-9. De Schryver EL, Algra A, van Gijn J (2007). Algra A ... Symptomatic treatment is recommended, possibly including a vasopressor drug. Gastric lavage should be considered. ...

*List of traditional Chinese medicines

"Herb-drug interactions". The Lancet. 355 (9198): 134-138. doi:10.1016/S0140-6736(99)06457-0. PMID 10675182. Amagase H, Nance DM ... In the classic Handbook of Traditional Drugs from 1941, 517 drugs were listed - 442 were plant parts, 45 were animal parts, and ... The human penis is not a drug - Li Shizhen Human penis is believed under TCM to stop bleeding, and as with other TCM medicines ... The theory of Northern Medicine is based on the Yin-Yang interactions and the eight trigrams, as used in Chinese Medicine. ...

*Dantrolene

"Dantrolene Drug Interactions". Epocrates Online. Epocrates. 2008. Retrieved on December 31, 2008. Snyder, H. R.; Davis, C. S.; ... It is the primary drug used for the treatment and prevention of malignant hyperthermia, a rare, life-threatening disorder ... Dantrolene may interact with the following drugs: Calcium channel blockers of the diltiazem/verapamil type: Intravenous ... therefore the drug should be given in pregnant women only if clearly indicated. It may cause hypotonia in the newborn if given ...

*Vitamin K

"Pradaxa Drug Interactions". Pradaxapro.com. 10 July 2017. Retrieved 10 July 2017. Bauersachs, R.; Berkowitz, S. D.; Brenner, B ... The proper anticoagulant action of the drug is a function of vitamin K intake and drug dose, and due to differing absorption ... National Institute of Health Clinical Center Drug-Nutrient Interaction Task Force. Retrieved 17 Apr 2015. "Guidelines For ... Sometimes small amounts of vitamin K are given orally to patients taking warfarin so that the action of the drug is more ...

*Nilotinib

Interaction of nilotinib with OATP1B1 and OATP1B3 may alter its hepatic disposition and can lead to transporter mediated drug- ... Bailey, David G; Malcolm, J; Arnold, O; David Spence, J (1998-08-01). "Grapefruit juice-drug interactions". British Journal of ... drug interactions. Nilotinib is an inhibitor of OATP-1B1 transporter but not for OATP-1B3. It is a substrate for CYP3A4 and ... https://www.cancer.gov/about-cancer/treatment/drugs/fda-nilotinib "Complete Nilotinib information from Drugs.com". Drugs.com. ...

*Norfloxacin

As such, these drug interactions involving the fluoroquinolones appear to be drug specific rather than a class effect. The ... Brouwers JR, JR (July 1992). "Drug interactions with quinolone antibacterials". Drug Saf. 7 (4): 268-81. doi:10.2165/00002018- ... Such drug interactions are associated with the molecular structural modifications of the quinolone ring, specifically ... Harder S, Fuhr U, Staib AH, Wolff T (November 1989). "Ciprofloxacin-caffeine: a drug interaction established using in vivo and ...

*Health effects of tobacco

ISBN 1-887424-14-8. [page needed] Kroon LA (2007). "Drug interactions with smoking". Am J Health Syst Pharm. 64 (18): 1917-1921 ... That means that drugs cleared by these enzymes are cleared more quickly in smokers, which may result in the drugs not working. ... Unlike some recreational drugs, nicotine does not measurably alter a smoker's motor skills, judgement, or language abilities ... Nutt, D; King, LA; Saulsbury, W; Blakemore, C (24 March 2007). "Development of a rational scale to assess the harm of drugs of ...

*CYP3A4

Flockhart DA (2007). "Drug Interactions: Cytochrome P450 Drug Interaction Table". Indiana University School of Medicine. ... "Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential toxicity for certain drugs". ... The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices ... a new drug-drug interaction". Circulation. 107 (1): 32-7. doi:10.1161/01.CIR.0000047060.60595.CC. PMID 12515739. Meyer MR, Bach ...

*Carbamazepine

Moody D (2004). "Drug interactions with benzodiazepines". In Raymon LP, Mozayani A. Handbook of Drug Interactions: a Clinical ... Carbamazepine has a potential for drug interactions; caution should be used in combining other medicines with it, including ... PMID 25486094 drugs.com drugs.com international listings for carbamazepine Archived 2015-06-19 at the Wayback Machine. Page ... Drug interactions with methadone]. Presse Médicale (in French). 28 (25): 1381-4. PMID 10506872. Kaniwa, N; Saito, Y (June 2013 ...

*Lovastatin

David G. Bailey, J. Malcolm, O. Arnold, J. David Spence (1998). "Grapefruit juice-drug interactions". Br J Clin Pharmacol 46 (2 ... Lovastatin (Merck's Mevacor) is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk ... As with all statin drugs, it can rarely cause myopathy, hepatotoxicity (liver damage), dermatomyositis or rhabdomyolysis. This ... As with atorvastatin, simvastatin, and other statin drugs metabolized via CYP3A4, drinking grapefruit juice during lovastatin ...

*Bergamot orange

Bailey, David G.; Malcolm, J.; Arnold, O.; Spence, J. David (1998). "Grapefruit juice-drug interactions". Br J Clin Pharmacol. ... grapefruit-drug interactions in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs ... Interactions and Warnings". WebMD. Retrieved 2016-01-04. "Online Etymology Dictionary". etymonline.com. "Collins Dictionaries ...

*6',7'-Dihydroxybergamottin

David G. Bailey; J. Malcolm; O. Arnold; J. David Spence (1998). "Grapefruit juice-drug interactions". Br J Clin Pharmacol. 46 ( ... it is believed to be responsible for a number of grapefruit-drug interactions, in which the consumption of the juice affects ... the metabolism of a variety of pharmaceutical drugs. Edwards, D.J.; F.H Bellevue, 3rd; P.M. Woster (December 1996). " ... "Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice". Drug Metabolism & Disposition ...

*Earl Grey tea

Bailey, D. G.; Malcolm, J.; Arnold, O.; Spence, J. D. (1998). "Grapefruit juice-drug interactions". British Journal of Clinical ... grapefruit-drug interactions in which the consumption of the juice affects the metabolism of a variety of pharmaceutical drugs ... who were found to have supplied tea "artificially scented, and, drugged with bergamot in this country." A "Grey's Tea" is known ...

*Buspirone

See grapefruit-drug interactions. Elevated blood pressure has been reported when buspirone has been administered to patients ... The drug has also been found to be effective in the treatment of depression as a standalone drug. There is evidence that ... Buspirone is metabolized primarily by CYP3A4, and prominent drug interactions with inhibitors and inducers of this enzyme have ... Jajoo, HK; Mayol, RF; LaBudde, JA; Blair, IA (1989). "Metabolism of the antianxiety drug buspirone in human subjects". Drug ...

*Rashad Murad

Applied Therapeutics 2017 •Drugs Interactions 2017 •Essentials of Pharmacology for Dentistry, Arabic-English Bilingual Edition ...

*Alcohol (drug)

Drug interaction facts. St. Louis: JB Lippincott Co, 1988, ISBN 0932686478. McCoy, HG; Cipolle, RJ; Ehlers, SM; Sawchuk, RJ; ... One of the most important drug/food interactions that should be noted is between alcohol and metronidazole. Metronidazole is an ... Beynon CM, McVeigh C, McVeigh J, Leavey C, Bellis MA (2008). "The involvement of drugs and alcohol in drug-facilitated sexual ... In accordance, the drug has been found to reverse many of the behavioral effects of low-to-moderate doses of ethanol in rodents ...

*Hemoencephalography

70% of sufferers saw a 50% or more reduction in their migraines following combined neurotherapy and drug treatment, as opposed ... while PIR had greater efficacy in the realms of emotional regulation and social interactions. With many symptoms reminiscent of ... allowing the patient to greatly reduce the drug therapy necessary for him to function successfully in school and offering a ... to 50% undergoing only traditional drug therapy. The term autism encompasses a wide range of syndromes, such as Rett disorder, ...

*Antihistamine

"Drug Interaction Report". drugs.com. Retrieved 28 January 2017. Yoneyama H, et al. (March 2008). "Efficient approaches to S- ... Research into these drugs led to the discovery that they were H1 antagonists and also to the development of H2 antagonists, ... The newer drugs are not necessarily safer or more effective. Because so many antihistamines are available, patients can have ... Antihistamines are drugs which treat allergic rhinitis and other allergies. Antihistamines can give relief when a person has ...