... inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21. Long noncoding RNA Prostate ...
The two most common regimens are cisplatin, doxorubicin, etoposide (EDP) + mitotane, and streptozotocin + mitotane. The FIRM- ...
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases. Breast ...
When anticancer drugs such as doxorubicin accumulate in microvesicles, the drug's cellular levels decrease. This can ultimately ...
Bartlett, NL; Lum, BL; Fisher, GA; Brophy, NA; Ehsan, MN; Halsey, J; Sikic, BI (1994). "A phase I trial of doxorubicin with ... Advani, R; Lum, BL; Fisher, GA; Halsey, J; Chin, DL; Jacobs, CD; Sikic, BI (2005). "A phase I trial of liposomal doxorubicin, ...
"Fluorescence intensity and lifetime imaging of free and micellar-encapsulated doxorubicin in living cells. Nanomedicine". (2008 ...
"Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection". ...
T cell lymphoma is typically treated using the CHOP regimen in which four anti-cancer drugs; cyclophosphamide, doxorubicin, ...
"ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3". Journal of Molecular ...
"Pegylated liposomal doxorubicin-associated hand-foot syndrome: recommendations of an international panel of experts". European ... doxorubicin, and fluorouracil and its prodrug capecitabine. Targeted cancer therapies, especially the tyrosine kinase ...
"MiR-375 and Doxorubicin Co-delivered by Liposomes for Combination Therapy of Hepatocellular Carcinoma". Molecular Therapy - ...
Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and carboplatin. On the other hand, therapies ...
Drugs in the anthraquinone family include the prototypical daunorubicin, doxorubicin, mitoxantrone, losoxantrone, and ...
Chemotherapy - Doxorubicin is one agent known to have heart toxicity (leads to dilated cardiomyopathy). Diuretics - The primary ... doxorubicin), tuberculosis, and pregnancy. Alcoholic cardiomyopathy - A type of dilated cardiomyopathy caused by chronic abuse ...
Doxorubicin has been shown to increase adenoviral replication in soft tissue sarcoma cells as well, potentially contributing to ... At least part of doxorubicin's mechanism of action is as an inducer of immunogenic cell death, and it has been suggested that ... ONCOS-102 has recently been studied in combination with doxorubicin, and a synergistic effect was observed. ... "Oncolytic adenovirus and doxorubicin-based chemotherapy results in synergistic antitumor activity against soft-tissue sarcoma ...
2013). "Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin". Nature ...
Doxorubicin, paclitaxel, and campothecin are examples of drugs typically used with polymer-drug conjugate systems. Hetero- ...
In 1993, Kabi Pharmacia bought Farmitalia, an Italian company that had developed doxorubicin, a chemotherapeutic. In 1995 the ...
"Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells". Mutation ...
The ATPase activity of Sav1866 is known to be stimulated by cancer drugs such as doxorubicin, vinblastine and others, which ... ABCG2 can export anthracycline anticancer drugs, as well as topotecan, mitoxantrone, or doxorubicin as substrates. Chromosomal ... and doxorubicin. It is unclear exactly how these proteins can translocate such a wide variety of drugs, however, one model (the ... annamycin and doxorubicin-peptide). These drugs would not function as a substrate of ABC transporters, and would thus not be ...
... metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer doxorubicin. ...
20 April 2010). "TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in ...
Doxorubicin, like other anticancer quinones, was used for chemotherapy in human cancers for many years. The mechanism of action ... The doxorubicin damages DNA by intercalation, the generation of reactive oxygen species and inhibition of DNA topoisomerase I ... Thus, while doxorubicin and other anthraquinones act through many mechanisms such as apoptosis, abrogation of the cell cycle ... 2007). "A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo ...
PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells". Cancer Chemotherapy and Pharmacology. 67 (2): ...
... doxorubicin, and dexamethasone: a case report". Cases J. 2 (1): 121. doi:10.1186/1757-1626-2-121. PMC 2644294. PMID 19192311. ...
Certain anticancer drugs such as doxorubicin (Doxil) and daunorubicin may be administered encapsulated in liposomes. Liposomal ...
Chemotherapy, including cisplatin, vincristine, cyclophosphamide, and doxorubicin are used for the systemic treatment of ...
A study was performed to assess the toxicity effects of doxorubicin-loaded polymeric nanoparticle systems. It was found that ... PIHCA, due to this slight advantage, is currently undergoing phase III clinical trials for transporting the drug doxorubicin as ...
... apoptosis and increased efficacy of doxorubicin in prostate cancer cells". Oncology Reports. 11 (2): 537-41. PMID 14719096. ...
"Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients". British Journal of Cancer. 107 ...