For example, Doxorubicin, a very common chemotherapeutic antibiotic, has many adverse side-effects. Researchers are looking for ... Links between doxorubicin adverse side-effects and chromosome metabolism and membrane transport were seen. Metabolic models for ... "Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission ... ways to further understand how doxorubicin works by observing the genes linked to resistance by using fission yeast as a model ...

In one study, leukosomes loaded with doxorubicin injected into murine models inhibited breast and melanoma tumor growth more ... Another study examined the differences in therapeutic behavior between liposomes and leukosomes both loaded with doxorubicin ... "Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma". Biomaterials Science ... better incorporated themselves into surrounding cells in vitro and served as an effective drug depot for the doxorubicin. ...

Specifically, successful encapsulation of the anti-cancer agent doxorubicin hydrochloride has been achieved. The low gelation ...

"Chemotherapeutic Sensitization of Leptomycin B Resistant Lung Cancer Cells by Pretreatment with Doxorubicin". PLOS ONE. United ...

Wu, Bo; Lu, Shu-Ting; Zhang, Liu-Jie; Zhuo, Ren-Xi; Xu, Hai-Bo; Huang, Shi-Wen (March 2017). "Codelivery of doxorubicin and ... "Novel reduction-sensitive micellar nanoparticles assembled from Rituximab-doxorubicin conjugates as smart and intuitive drug ... "Folate-containing reduction-sensitive lipid-polymer hybrid nanoparticles for targeted delivery of doxorubicin". Biomaterials ...

"Swarming carbon dots for folic acid mediated delivery of doxorubicin and biological imaging". Journal of Materials Chemistry B ... "Carbon dots functionalized gold nanorod mediated delivery of doxorubicin: Tri-functional nano-worms for drug delivery, ...

Doxorubicin was combined with docetaxel in one study of 24 patients and resulted in an increased AUC of docetaxel by 50 to 70 ... Cisplatin, dexamethasone, doxorubicin, etoposide, and vinblastine are all potentially co-administered with docetaxel and did ... The third case involved pyloric stenosis in an infant whose mother received a combination regimen of docetaxel, doxorubicin, ... The treatment of breast cancer with doxorubicin and cyclophosphamide is enhanced by adjuvant treatment with docetaxel. ...

One of the most common regimens, known as "AC", combines cyclophosphamide with doxorubicin. Sometimes a taxane drug, such as ... Damage to the heart muscle is the most dangerous complication of doxorubicin, for example.[citation needed] Trastuzumab, a ...

Examples include doxorubicin (adriamycin) and daunorubicin (both of which are used in treatment of Hodgkin's lymphoma), and ... Intensively studied DNA intercalators include berberine, ethidium bromide, proflavine, daunomycin, doxorubicin, and thalidomide ...

September 2018). "Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a ... Several groups have encapsulated anti-cancer medications such as: Camptothecin, Methotrexate, and Doxorubicin. Results from ...

"Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells". World Journal of Gastroenterology ...

Shen Y, Liu S, Fan J, Jin Y, Tian B, Zheng X, Fu H (April 2017). "Nuclear retention of the lncRNA SNHG1 by doxorubicin ...

Wohlfart, S., Khalansky, A. S., Gelperina, S., Begley, D., & Kreuter, J. (2011). Kinetics of transport of doxorubicin bound to ... Studies have shown that "the overcoating of the [nanoparticles] with polysorbate 80 yielded doxorubicin concentrations in the ...

Unlike CHOP, this chemotherapy regimen does not contain doxorubicin or any other anthracycline. Thus, it can be used in ... patients with severe cardiovascular diseases and contraindications for doxorubicin-containing regimens. This regimen also does ...

... doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and ...

S. peucetius produces the anthracycline antitumor antibiotics daunorubicin and doxorubicin (also known as adriamycin). Recent ...

March 2004). "Phase I and pharmacokinetic study of MCC-465, a doxorubicin (DXR) encapsulated in PEG immunoliposome, in patients ... "Cellular trafficking and cytotoxicity of anti-CD19-targeted liposomal doxorubicin in B lymphoma cells". Journal of Liposome ...

"Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin". Nature ...

Invasive thymomas may require additional treatment with radiotherapy and chemotherapy (cyclophosphamide, doxorubicin and ...

May 2010). "Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells". J. ...

Doxorubicin and suramin are both DNA and NTP competitive inhibitors of Mycobacterium Tuberculosis DnaG. Suramin is also known ...

"Inhibition of cyclin-dependent kinase 2 protects against doxorubicin-induced cardiomyocyte apoptosis and cardiomyopathy". The ...

Poisons of type II topoisomerases include doxorubicin, etoposide, novobiocin, quinolones (including ciprofloxacin), and ...

"Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells". Journal of ...

Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and carboplatin. On the other hand, therapies ...

... inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21. Long noncoding RNA Prostate ...

The two most common regimens are cisplatin, doxorubicin, etoposide (EDP) + mitotane, and streptozotocin + mitotane. The FIRM- ...

Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases. Breast ...

When anticancer drugs such as doxorubicin accumulate in microvesicles, the drug's cellular levels decrease. This can ultimately ...

Bartlett, NL; Lum, BL; Fisher, GA; Brophy, NA; Ehsan, MN; Halsey, J; Sikic, BI (1994). "A phase I trial of doxorubicin with ... Advani, R; Lum, BL; Fisher, GA; Halsey, J; Chin, DL; Jacobs, CD; Sikic, BI (2005). "A phase I trial of liposomal doxorubicin, ...