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*  Domperidone
... , sold under the brand name Motilium among others, is a peripherally selective dopamine D2 receptor antagonist that ... Domperidone is a peripherally selective dopamine D2 and D3 receptor antagonist. It has no clinically significant interaction ... It blocks dopamine receptors in the anterior pituitary gland increasing release of prolactin which in turn increases lactation ... Parkinson's disease is a chronic neurological condition where a decrease in dopamine in the brain leads to rigidity (stiffness ...
*  Dopamine antagonist
Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting. Dopamine receptor antagonists ... Dopamine agonist Dopaminergic Serotonin antagonist Adrenergic antagonist Histamine antagonist Acetylcholine antagonist GABA ... A dopamine antagonist (antidopaminergic) is a type of drug which blocks dopamine receptors by receptor antagonism. Most ... MeSH list of agents 82018492 Dopamine antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Aboulia
... dopamine antagonists). Treat depression efficaciously when both DDM and depression are present. Increase motivation through use ... As a result of more and more evidence showing that the mesolimbic and the mesocortical dopamine system are key to motivation ... of stimulants, dopamine agonists, or other agents such as cholinesterase inhibitors. A case of aboulia after a transient ... and responsiveness to reward, aboulia may be a dopamine-related dysfunction. Aboulia may also result from a variety of brain ...
*  Andre Soriano
"Dopamine Antagonist - Andre Soriano Bridal Campaign". 26 July 2013. "Not For the Classic Princess: Extreme Bridal by Andre ...
*  Piribedil
Dopamine receptor antagonist, selective for subtypes D4. Adrenergic receptor antagonist, subtypes α2A and α2C: could be the ... Dopamine antagonists reduce the effect of piribedil. At very high doses, piribedil has an emetic action on the chemoreceptor ... Agonist and Antagonist Properties at Subtypes of Dopamine D2-Like Receptor and α1/α2-Adrenoceptor" (PDF). J. Pharmacol. Exp. ... As with other dopamine agonists (like pramipexole and ropinirole), compulsive behavior like pathological gambling, overeating, ...
*  Azapride
... is the azide derivative of the dopamine antagonist clebopride synthesized in order to label dopamine receptors. It is ... an irreversible dopamine antagonist. Niznik HB, Guan JH, Neumeyer JL, Seeman P. (1985) 'A photoaffinity ligand for dopamine D2 ... Wouters W, Van Dun J, Laduron PM.(1984),'Photoaffinity labelling of dopamine receptors. Synthesis and binding characteristics ...
*  Iloperidone
The older typical antipsychotics are primarily dopamine antagonists. Iloperidone has been shown to act as an antagonist at all ... It exhibits high (nM) affinity to serotonin 5HT2A (Ki value of 5.6 nM), dopamine D2 (6.3 nM) and D3 (7.1 nM) and noradrenaline ... particularly multiple dopamine and serotonin receptor subtypes. It is considered an 'atypical' antipsychotic because it ... dopamine D1 and histamine H1 receptors. In addition, pharmacogenomic studies identified single nucleotide polymorphisms ...
*  Zuclopenthixol
As with other dopamine antagonists, zuclopenthixol may sometimes elevate prolactin levels; this may occasionally result in ... Zuclopenthixol is a D1 and D2 antagonist, α1-adrenergic and 5-HT2 antagonist. While it is approved for use in Australia, Canada ... An increase in the incidence of pancreatic islet cell tumours has been observed for some other D2 antagonists. The ... An increase in the incidence of mammary adenocarcinomas is a common finding for D2 antagonists which increase prolactin ...
*  Eticlopride
... is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological ... "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus ...
*  Cabergoline
Dopamine antagonists such as antipsychotics and metoclopramide counteract some effects of cabergoline. The use of ... March 2010). "Can dopamine agonists reduce the incidence and severity of OHSS in IVF/ICSI treatment cycles? A systematic review ... Cabergoline functions as an agonist at all of these receptors except for 5-HT7 and α2B-, where it acts as an antagonist. ... Cabergoline is a long-acting dopamine D2 receptor agonist and in vitro rat studies show a direct inhibitory effect on the ...
*  Antagonism (chemistry)
Antagonists such as dopamine antagonist slow down movement in lab rats. Although they hinder the joining of enzymes to ... "Single exposure of dopamine D1 antagonist prevents and D2 antagonist attenuates methamphetamine effect". Journal of ... For instance, a receptor antagonist is an agent that reduces the response that a ligand produces when the receptor antagonist ... The effects of antagonists can be seen after they have encountered an agonist, and as a result, the effects of the agonist is ...
*  Paroxysmal sympathetic hyperactivity
Chlorpromazine and haloperidol, both dopamine antagonists, in some cases have worsened PSH symptoms. These drugs are in use ... Bromocriptine is a dopamine agonist that helps lower blood pressure. Its effects are modest, but they are not well understood. ... Other drugs that have been used and have in some cases been helpful are dopamine agonists, other various opiates, ...
*  Allyl cyanide
Treatment by serotonin and dopamine antagonists caused a reduction in the behavioral abnormalities. Ataxia, trembling, ... The serotonin and dopamine systems are thought to be involved in the behavioral abnormalities caused by allyl cyanide. ...
*  Vomiting
Hence, anticholinergics, antihistamines, dopamine antagonists, serotonin antagonists, and cannabinoids are used as antiemetics ... The neurotransmitters that regulate vomiting are poorly understood, but inhibitors of dopamine, histamine, and serotonin are ... The chemoreceptor trigger zone at the base of the fourth ventricle has numerous dopamine D2 receptors, serotonin 5-HT3 ...
*  Perazine
It is quite similar to chlorpromazine, and acts as a dopamine antagonist. A 2014 systematic review compared it with other ...
*  UH-232
"Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal ... UH-232 ((+)-UH232) is a drug which acts as a subtype selective mixed agonist-antagonist for dopamine receptors, acting as a ... Lahti, AC; Weiler, M; Carlsson, A; Tamminga, CA (1998). "Effects of the D3 and autoreceptor-preferring dopamine antagonist (+)- ... "The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study". European ...
*  H3 receptor antagonist
Current treatments are based on first and second generation antipsychotics which are dopamine antagonists. These drugs have ... Even if H3R antagonist don't seem to be effective against positive symptoms of SCH studies have shown that H3R antagonists may ... A general structural pattern that is necessary for the antagonist affinity for H3R has been described. An H3R antagonist needs ... Consequently, unlike the H1 antagonist antihistamines which are sedating, H3 antagonists have stimulant and nootropic effects, ...
*  Spiroxatrine
It is an analog of spiperone and also has some dopamine antagonist effects. Terrón, J. A.; Ibarra, M; Ransanz, V; Hong, E; ... Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor. ...
*  Gastroparesis
In addition, dopamine antagonist action in the central nervous system prevents nausea and vomiting. Similarly, the dopamine ... Metoclopramide, a dopamine D2 receptor antagonist, increases contractility and resting tone within the GI tract to improve ... receptor antagonist domperidone is also used to treat gastroparesis. Erythromycin is known to improve emptying of the stomach ...
*  Dopamine
... and most antipsychotic drugs used to treat this are dopamine antagonists which reduce dopamine activity. Similar dopamine ... Once in the synapse, dopamine binds to and activates dopamine receptors. These can be postsynaptic dopamine receptors, which ... Dopamine Minor: L-Phenylalanine → m-Tyrosine → m-Tyramine → Dopamine The direct precursor of dopamine, L-DOPA, can be ... In some cases, D2-receptor antagonists such as metoclopramide are useful as anti-nausea drugs. There are no reports of dopamine ...
*  Opioid
5-HT3 antagonists (e.g. ondansetron) Dopamine antagonists (e.g. domperidone) Anti-cholinergic antihistamines (e.g. ... A less expensive alternative is dopamine antagonists such as domperidone and metoclopramide. Domperidone does not cross the ... when an antagonist (e.g., naloxone) or an agonist-antagonist (e.g., pentazocine) is administered. Physical dependence is a ... antagonists, and mixed agonist-antagonists could best be explained by actions on multiple opiate receptors. Courtwright, David ...
*  Nausea
... and vomiting associated with migraine headaches respond best to dopamine antagonists such as metoclopramide, ... In cases of gastroenteritis, serotonin antagonists such as ondansetron were found to suppress nausea and vomiting, as well as ... Activation of the CTZ is mediated by dopamine (D2) receptors, serotonin (5HT3) receptors, and neurokinin receptors (NK1). ...
*  Psychopharmacology
... dopamine antagonists). For an antipsychotic to be effective, it generally requires a dopamine antagonism of 60%-80% of dopamine ... because the neuroleptics antagonize dopamine receptors broadly, also reducing the normal dopamine-mediated inhibition of ... It increases norepinephrine, dopamine, and 5-HT and thus increases the action of the transmitters at their receptors. MAOIs ... Some of the efficacy of atypical antipsychotics may be due to 5-HT2 antagonism or the blockade of other dopamine receptors. ...
*  Clebopride
... is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal ...
*  Tardive dyskinesia
Other dopamine antagonists and antiemetics can cause tardive dyskinesia, such as metoclopramide and promethazine, used to treat ... with the D2 dopamine receptor being most affected. Neuroleptics act primarily on this dopamine system, and older neuroleptics, ... Tetrabenazine, which is a dopamine depleting drug, is sometimes used to treat tardive dyskinesia and other movement disorders. ... The most compelling line of evidence suggests that tardive dyskinesia may result primarily from neuroleptic-induced dopamine ...
*  Budipine
... it is believed to be an NMDA receptor antagonist, but also promoting the synthesis of dopamine. Because it provides additional ... PMID 8821048 Gene C. Palmer (September 2001). "Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies". ... "Effects of amantadine and budipine on antidepressant drug-evoked changes in extracellular dopamine in the frontal cortex of ...
*  Induced ovulation (animals)
Advances in application of GnRH analogues and dopamine antagonists". Aquaculture. Induced Spawning of Asian Fishes. 74 (1): 1- ... bream and loach are able to be induced to ovulate by using agonists of dopamine. This induction of ovulation from drugs is able ...