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*  Prenatal cocaine exposure
The most important way cocaine affects fetal development is by binding to dopamine receptors. Another possible mechanism by ... Cocaine prevents the reuptake of the neurotransmitters dopamine, serotonin, and norepinephrine. Thus they stay in the synapse ... and may have abnormalities in dopamine processing. Animal research has also shown that offspring of males that used cocaine ...
*  Cocaethylene
... and dopamine transporter. These pharmacological properties make cocaethylene a serotonin-norepinephrine-dopamine reuptake ... The monoamine neurotransmitters serotonin, norepinephrine, and dopamine play important roles in cocaethylene's action in the ... Cocaethylene has a higher affinity for the dopamine transporter than does cocaine, but has a lower affinity for the serotonin ... a unique cocaine metabolite displays high affinity for the dopamine transporter". Journal of Neurochemistry. 56 (2): 698-701. ...
*  Cocaine intoxication
Cocaine's acute effect in the central nervous system is to raise the amount of dopamine and serotonin in the nucleus accumbens ... "Decreased brain dopamine cell numbers in human cocaine users". Psychiatry Research. 168 (3): 173-180. doi:10.1016/j.psychres. ... dopamine, epinephrine, norepinephrine, and serotonin) re-uptake transporters with equal affinity. Monoamines accumulate in the ... focus on dopamine, norepinephrine and glutamate". Pharmacology & Therapeutics. 134 (2): 260-277. doi:10.1016/j.pharmthera. ...
*  Dopamine
Once in the synapse, dopamine binds to and activates dopamine receptors. These can be postsynaptic dopamine receptors, which ... Dopamine Minor: L-Phenylalanine → m-Tyrosine → m-Tyramine → Dopamine The direct precursor of dopamine, L-DOPA, can be ... and most antipsychotic drugs used to treat this are dopamine antagonists which reduce dopamine activity. Similar dopamine ... Some of the dopamine in plants is likely to be used as a precursor for dopamine-melanin. The complex patterns that appear on ...
*  Dopamine receptor
The resulting dopamine receptor heterodimers include: D1-adenosine A1 D1-D2 dopamine receptor heteromer D1-D3 dopamine receptor ... The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine receptors are implicated in ... Dopamine is the primary neurotransmitter involved in the reward pathway in the brain. Thus, drugs that increase dopamine ... D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of ...
*  Dopamine (film)
Official website Dopamine on IMDb Dopamine at AllMovie Dopamine at Rotten Tomatoes Dopamine at Metacritic. ... Dopamine at Rotten Tomatoes Dopamine at Metacritic Livingston, John; Lloyd, Sabrina; Campos, Bruno; Grundy, Rueben (2003-01-23 ... Dopamine is a 2003 romantic comedy-drama film written and directed by Mark Decena. Rand is a computer animator, who has created ... Dopamine, retrieved 2017-03-19 "Sundance Film Festival Films Honored 1985-2007" (PDF). Archived from the original (PDF) on 2008 ...
*  Dopamine (disambiguation)
Dopamine (medication) a medication used to treat a number of health problems Dopamine receptor Dopamine transporter Dopamine ( ... Dopamine is a chemical naturally produced in the body. Dopamine may also refer to: ... a record label Dopamine (Third Eye Blind album), an album by Third Eye Blind Dopamine (BØRNS album), an album by BØRNS " ... "Dopamine", a song from the album Fused by Tony Iommi and Glenn Hughes Dopamin, an album by the German band Böhse Onkelz " ...
*  Dopamine transporter
Once dopamine binds, the protein undergoes a conformational change, which allows both sodium and dopamine to unbind on the ... The rate at which DAT removes dopamine from the synapse can have a profound effect on the amount of dopamine in the cell. This ... Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses, although there may be ... The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the ...
*  Dopamine antagonist
A dopamine antagonist (antidopaminergic) is a type of drug which blocks dopamine receptors by receptor antagonism. Most ... Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting. Dopamine receptor antagonists ... trimipramine Choline can antagonize dopamine directly or interfere with receptor function Melatonin suppresses dopamine ... MeSH list of agents 82018492 Dopamine antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Dopamine agonist
A dopamine receptor agonist is a compound that activates dopamine receptors. Dopamine receptor agonists activate signaling ... There are two classes of drugs that act as indirect agonists of dopamine receptors: dopamine reuptake inhibitors and dopamine ... Some medical drugs act as dopamine agonists and can treat hypodopaminergic (low dopamine) conditions; they are typically used ... Dopamine antagonist Dopamine reuptake inhibitor Receptor agonist GABA receptor agonist Dopaminergic Serotonin agonist ...
*  Dopamine (medication)
It is unclear if dopamine is safe to use during pregnancy or breastfeeding. At low doses dopamine mainly triggers dopamine ... Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine ... While some effects result from stimulation of dopamine receptors, the prominent cardiovascular effects result from dopamine ... Dopamine was first synthesized in a laboratory in 1910 by George Barger and James Ewens in England. It is on the World Health ...
*  Dopamine Records
Shumaker founded Dopamine as a cassette-only indie label in 1995 and merged with Maniatis' label Amalagate Records in 2000. ... He assembled an able and energetic team to carry out a vision for continuing to put out superb music in keeping with Dopamine ... In April 2008, Dopamine announced a new partnership between themselves and Boston's DJ Die Young (Basstown, Solid!) and ... In 2010 Dopamine records merged with Maniatis' new company MMMMAVEN. Originally formed by Nate Shumaker, Alexander Maniatis, ...
*  Dopamine therapy
... is the regulation of levels of the neurotransmitter dopamine through the use of either agonists, or ... Dopamine replacement therapy (DRT) is an effective treatment for patients suffering from decreased levels of dopamine. Often ... One dopamine precursor, Levodopa, was the first drug approved specifically for Parkinson's disease. DRT increases dopamine in ... Impairment in these areas can be treated with dopamine agonists, a group of medications that mimics the ligand dopamine and ...
*  Dopamine receptor D5
D5 receptor is a subtype of the dopamine receptor that has a 10-fold higher affinity for dopamine than the D1 subtype. The D5 ... Wood M, Dubois V, Scheller D, Gillard M (2014). "Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine ... "Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1". Nature. 350 (6319): 614-9. doi ... "Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1". Nature. 350 (6319): 614-619. ...
*  Dopamine receptor D3
... is a protein that in humans is encoded by the DRD3 gene. This gene encodes the D3 subtype of the dopamine ... "Entrez Gene: DRD3 dopamine receptor D3". Joyce JN, Millan MJ (February 2007). "Dopamine D3 receptor agonists for protection and ... Dopamine receptor D3 has been shown to interact with CLIC6 and EPB41L1. Dopamine receptor Le Coniat M, Sokoloff P, Hillion J, ... a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats". European ...
*  Dopamine receptor D4
As with other dopamine receptor subtypes, the D4 receptor is activated by the neurotransmitter dopamine. It is linked to many ... The dopamine receptor D4 is a G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of ... Wu J, Xiao H, Sun H, Zou L, Zhu LQ (June 2012). "Role of dopamine receptors in ADHD: a systematic meta-analysis". Molecular ... 7R appears to react less strongly to dopamine molecules. The 48-base pair VNTR has been the subject of much speculation about ...
*  Dopamine (Børns album)
Album Review] Børns - 'Dopamine'". The Daily Listening. "Børns - Dopamine". Album of the Year. "iTunes - Music - Dopamine by ... "Album Review of Dopamine by Børns - Alternative Addiction - New Music First - Music News". "Børns - 'Dopamine' (ALBUM REVIEW ... "Børns: Dopamine review - emphatic retro-futurism turns tepid". the Guardian. "Børns deliver on cohesive, original 'Dopamine'". ... "BORNS - Dopamine ALBUM REVIEW". the paper. "Review: 'Dopamine' by Børns - The Stylegazer". The Stylegazer. "[ ...
*  Dopamine dysregulation syndrome
In accordance with the role of dopamine in reward processing, addictive drugs stimulate dopamine release. Although the exact ... or dopamine agonists (such as pramipexole or ropinirole) to patients. Dopamine replacement therapy is well known to improve ... "Resolution of dopamine dysregulation syndrome following cessation of dopamine agonist therapy in Parkinson's disease". J Clin ... Dopamine has been related to the normal learning of stimuli with behavioral and motivational significance, attention, and most ...
*  N-Arachidonoyl dopamine
... the indirect biosynthesis of phospholipid esters with dopamine may be possible, as dopamine can induce the aminolysis of the ... N-Arachidonoyl dopamine (NADA) is an endocannabinoid that acts as an agonist of the CB1 receptor and the transient receptor ... Yoo, Jae-Myung; Park, Eun Seok; Kim, Mee Ree; Sok, Dai-Eun (2013-04-01). "Inhibitory effect of N-Acyl dopamines on IgE-mediated ... It has been proposed to be conjugated from arachidonoyl-CoA or arachidonoyl phospholipids and dopamine, but in vitro ...
*  Dopamine releasing agent
A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain. No selective ... Many releasing agents of both dopamine and norepinephrine (norepinephrine-dopamine releasing agents, or NDRAs) and of serotonin ... Monoamine releasing agent Norepinephrine-dopamine releasing agent Serotonin-dopamine releasing agent Serotonin-norepinephrine- ... norepinephrine, and dopamine are known (serotonin-norepinephrine-dopamine releasing agents, or SNDRAs), however. Examples of ...
*  Dopamine receptor D2
The dopamine D2 receptor is the main receptor for most antipsychotic drugs. This gene encodes the D2 subtype of the dopamine ... Hasbi A, O'Dowd BF, George SR (Feb 2010). "Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates ... "History of the discovery of the antipsychotic dopamine D2 receptor: a basis for the dopamine hypothesis of schizophrenia". ... Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul ...
*  Dopamine receptor D1
"Entrez Gene: DRD1 dopamine receptor D1". Zhang J, Xiong B, Zhen X, Zhang A (2009). "Dopamine D1 receptor ligands: where are we ... The D1 subtype of the dopamine receptor is the most abundant dopamine receptor in the central nervous system. This G-protein ... "Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to ... "Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1". Nature. 350 (6319): 614-9. doi ...
*  Dopamine reuptake inhibitor
Lack of dopamine reuptake and the increase in extracellular levels of dopamine have been linked to increased susceptibility to ... There are very distinct differences in the mode of action between dopamine releasers/substrates & dopamine re-uptake inhibitors ... A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter ... dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine ...
*  Dopamine beta-hydroxylase
... dopamine beta-monooxygenase dopamine beta-hydroxylase membrane-associated dopamine beta-monooxygenase (MDBH) soluble dopamine ... Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC 1.14.17.1) that in humans is ... Dopamine beta-hydroxylase catalyzes the hydroxylation of not only dopamine but also other phenylethylamine derivatives when ... Inadequate DBH is called dopamine beta hydroxylase deficiency. Because it is difficult to obtain a stable crystal of dopamine ...
*  Norepinephrine-dopamine disinhibitor
Norepinephrine and dopamine disinhibitors (NDDIs) are a class of drugs which act at specific sites to disinhibit downstream ... Flibanserin disinhibits norepinephrine and dopamine release in the prefrontal cortex by activating 5-HT1A receptors in this ... Agomelatine, an antidepressant which disinhibits norepinephrine and dopamine release in the frontal cortex by antagonizing 5- ... Stahl SM (October 2007). "Novel mechanism of antidepressant action: norepinephrine and dopamine disinhibition (NDDI) plus ...