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*  Transposase
... and thus eliminating the transposable element. One of the reasons Tn5 is so unreactive is because the N- and C-termini are ... Transposase then binds to the DNA strand and creates a clamp over the transposon end of the DNA and inserts into the active ... "Comparative analysis of transposable element vector systems in human cells". Molecular Therapy. 18 (6): 1200-9. doi:10.1038/mt. ... Because DNA transposition events are inherently mutagenic, the low activity of transposases is necessary to reduce the risk of ...
*  LTR retrotransposon
... s are class I transposable element characterized by the presence of Long Terminal Repeats (LTR) directly ... Mobile DNA. 2 (1): 4. doi:10.1186/1759-8753-2-4. PMC 3059260 . PMID 21371312. Weber, B; Heitkam, T; Holtgräwe, D; Weisshaar, B ... Ogre-elements are gigantic Ty3-gypsy retrotransposons reaching lengths up to 25 kb. Ogre elements have been first described in ... December 2007). "A unified classification system for eukaryotic transposable elements". Nat. Rev. Genet. 8 (12): 973-82. doi: ...
*  Genome evolution
Transposable elements are regions of DNA that can be inserted into the genetic code through one of two mechanisms. These ... The most common transposable element in the human genome is the Alu sequence, which is present in the genome over one million ... "A unified classification system for eukaryotic transposable elements". Nature Reviews Genetics. 8 (12): 973-82. doi:10.1038/ ... Gene duplication is the process by which a region of DNA coding for a gene is duplicated. This can occur as the result of an ...
*  Retrotransposon
Like DNA transposable elements (class II transposons), retrotransposons can induce mutations by inserting near or within genes ... SVA are one of the youngest transposable element in great apes genome and among the most active and polymorphic in the human ... In wheat, about 90% of the genome consists of repeated sequences and 68% of transposable elements. In mammals, almost half the ... Retrotransposons, also known as class I transposable elements, consist of two subclasses, the long terminal repeat (LTR- ...
*  Robert A. Martienssen
Martienssen's work explains the effect on plants of 'jumping genes', or DNA transposable elements, reported in 1951 by Barbara ... "Transposable elements and the epigenetic regulation of the genome". Nature Reviews Genetics. 8 (4): 272-285. doi:10.1038/ ... Working with maize, yeast and the weed Arabidopsis, he focuses on the chemical modifications to DNA that determine which genes ... "A diffusion model for the coordination of DNA replication in Schizosaccharomyces pombe". Scientific Reports. 6: 18757. doi: ...
*  List of MeSH codes (G06)
... dna transposable elements MeSH G06.184.603.080.708.330.200.500 --- integrons MeSH G06.184.603.080.708.330.330 --- genomic ... alu elements MeSH G06.184.603.080.708.800 --- tandem repeat sequences MeSH G06.184.603.080.708.800.140 --- dna repeat expansion ... e-box elements MeSH G06.184.603.080.689.330.400 --- hiv enhancer MeSH G06.184.603.080.689.330.700 --- response elements MeSH ... vitamin d response element MeSH G06.184.603.080.689.390 --- insulator elements MeSH G06.184.603.080.689.450 --- locus control ...
*  Genome size
Junk DNA List of sequenced eukaryotic genomes Noncoding DNA Plant DNA C-values Database Selfish DNA Transposable elements ... Genome size is the total amount of DNA contained within one copy of a single genome. It is typically measured in terms of mass ... I. DNA-content and chromosome sets in various species of Cyprinidae". Humangenetik. 7 (3): 240-244. doi:10.1007/BF00273173. ... Drake, J W (1991). "A constant rate of spontaneous mutation in DNA-based microbes". Proc Natl Acad Sci USA. 88: 7160-7164. doi: ...
*  Alu element
... and provided the definitive link between transposable elements (active elements) and interspersed repetitive DNA (mutated ... Alu elements are retrotransposons and look like DNA copies made from RNA polymerase III-encoded RNAs. Alu elements do not ... Kidwell, Margaret G; Lisch, Damon R (2001). "Perspective: Transposable Elements, Parasitic Dna, and Genome Evolution". ... Alu elements are the most abundant transposable elements, containing over one million copies dispersed throughout the human ...
*  List of MeSH codes (G14)
... dna transposable elements MeSH G14.080.708.330.330 --- genomic islands MeSH G14.080.708.330.800 --- retroelements MeSH G14.080. ... dna transposable elements MeSH G14.340.024.425.500 --- genomic islands MeSH G14.340.024.425.800 --- retroelements MeSH G14.340. ... serum response element MeSH G14.080.689.330.700.920 --- vitamin d response element MeSH G14.080.689.390 --- insulator elements ... alu elements MeSH G14.080.708.800 --- tandem repeat sequences MeSH G14.080.708.800.074 --- dna repeat expansion MeSH G14.080. ...
*  Margaret Kidwell
Kidwell, M. G. and D. R. Lisch (2001) Perspective: Transposable elements, parasitic DNA and genome evolution. Evolution 55:1-24 ... Transposable elements as sources of variation in animals and plants. Proc. Natl. Acad. Sci. 94: 7704-7711. ... lead to collaborative studies resulting in the discovery of hybrid dysgenesis and the isolation of transposable P elements. ... at the University of Arizona has increasingly focused on the evolutionary significance of transposable genetic elements. In ...
*  Epigenetic regulation of transposable elements in the plant kingdom
Transposable elements (transposons, TEs, 'jumping genes') are short strands of repetitive DNA that can self-replicate and ... Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis." Genome ... While transposable elements may affect any number of different cell-types in an animal, be a skin cell, a liver cell, a brain ... Though transposable elements were discovered due in large part to their deleterious effects, epigenetic research has shown that ...
*  Horizontal gene transfer
A transposable element (TE) (also called a transposon or jumping gene) is a mobile segment of DNA that can sometimes pick up a ... Successful transfer of a transposable element requires delivery of DNA from donor to host cell (and to the germ line for multi- ... HTT can occur with any type of transposable elements, but DNA transposons and LTR retroelements are more likely to be capable ... Schaack S, Clement G, Cedric F (2010). "Promiscuous DNA: Horizontal Transfer of Transposable Elements and Why It Matters for ...
*  Mobile genetic elements
Transposons (also called transposable elements) are DNA sequences that can move locations within a genome, which includes ... Then, the DNA sequence can be inserted back to a random location of the genome. DNA transposons are a DNA segment that can move ... Transposition by transposable elements is mutagenic. Thus, organisms have evolved to repress the transposition events, and ... In addition, CRISPR-Cas controls transposable elements for their propagation. MGEs such as plasmids by a horizontal ...
*  Retrotransposon marker
"Genomic deletions and precise removal of transposable elements mediated by short identical DNA segments in primates". Genome ... The analysis of SINEs - Short INterspersed Elements - LINEs - Long INterspersed Elements - or truncated LTRs - Long Terminal ... October 2003). "Alu elements and hominid phylogenetics". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 12787-91. doi:10.1073/pnas. ... The target sites are relatively unspecific so that the chance of an independent integration of exactly the same element into ...
*  Selfish genetic element
... introns as mobile genetic elements Junk DNA Mobile genetic elements Mutation Noncoding DNA Retrotransposon Transposable element ... units of selfish DNA affect their replication by exploiting existing DNA and DNA-manipulating mechanisms in the cell, ... Selfish genetics elements (also sometimes called selfish DNA) are genetic sequences that spread by forming additional copies of ... Homing endonuclease genes (HEGs) cleave DNA at its own site on the homologous chromosome, triggering the DNA double-stranded ...
*  Maelstrom gene
In addition, spermatogenesis fails due to sperm DNA damage caused by the derepression of transposable elements. MAEL has also ... Short RNAs are well-known to silence TEs (transposable elements) through the RNAi (RNA interference) pathway, and Piwi- ... Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation. Molecular Biology Reports. 37: ...
*  Repeated sequence (DNA)
interspersed nuclear elements) Transposable elements DNA transposons retrotransposons LTR-retrotransposons (HERVs) non LTR- ... "Selfish dna." (1980): 645-646. McClintock B.Controlling element and the gene. Cold Spring Harb. Symp. Quant. Biol. 1956;21:197- ... Repeated sequences (also known as repetitive elements, or repeats) are patterns of nucleic acids (DNA or RNA) that occur in ... ISBN 978-1-84800-254-8. Function of Repetitive DNA DNA Repetitious Region at the US National Library of Medicine Medical ...
*  Picea abies
... including long terminal repeat transposable elements. Despite recent advances in massively parallel DNA sequencing, the ... A large proportion of the spruce genome consists of repetitive DNA sequences, ...
*  Micropia
... : a retrotransposon of Drosophila combining structural features of DNA viruses, retroviruses and non-viral transposable ... The name micropia is an artificial word, i.e. a concoction of "microcloning" and "copia-like element". 1. Huijser, P., C. ... elements. J Mol Biol 204:233-46. 3. Lankenau, S., V. G. Corces, and D. H. Lankenau. 1994. The Drosophila micropia ...
*  Miniature Inverted-repeat Transposable Elements
"Miniature inverted-repeat transposable elements (MITEs) and their relationship with established DNA transposons." In Mobile DNA ... Miniature Inverted-repeat Transposable Elements (MITEs) are a group of non-autonomous Class II transposable elements. Being non ... Lu, C; Chen, J; Zhang, Y; Hu, Q; Su, W; Kuang, H (2013-03-25). "Miniature Inverted-Repeat Transposable Elements (MITEs) Have ... They can form stable DNA secondary structures which can be very useful in identifying them. A few Stowaway elements also ...
*  RNA polymerase IV
The siRNA plays a major role in defending the genome against the invading viruses and transposable elements by RNA directed DNA ... Herr, A. J. , M. B. Jensen, T. Dalmay, and D. C. Baulcombe (2005). "RNA Polymerase IV Directs Silencing of Endogenous DNA". ... RNA polymerase silences the transposons and repetitive DNA in the siRNA pathway. ...
*  Behavior mutation
Spontaneous mutations arise from sources including errors in DNA replication, spontaneous lesions, and transposable genetic ... "Shaping bacterial genomes with integrative and conjugative elements". Research in Microbiology. 155 (5): 376-86. doi:10.1016/j. ... It can occur during meiosis or replication of DNA, as well as due to ionizing or UV radiation, transposons, mutagenic chemicals ... Carroll, Sean B.; Grenier, Jennifer; Weatherbee, Scott (2005). From DNA to Diversity: Molecular Genetics and the Evolution of ...
*  Jerzy Jurka
... a novel class of giant transposable elements widespread in eukaryotes and related to DNA viruses". Gene. 390 (April): 3-17. doi ... Jurka is best known for his work on eukaryotic transposable elements (TEs), including the discovery of the major families of ... In 2006 they reported a study of a new, self-synthesizing transposable element called Polinton or Maverick, which is present ... Jurka J, Bao W, Kojima K (June 2011). "Families of transposable elements, population structure and the origin of species". ...
*  Polinton
... a novel class of giant transposable elements widespread in eukaryotes and related to DNA viruses". Gene. 390 (1-2): 3-17. doi: ... Giant transposable elements were originally discovered in the mid-2000s, beginning with the description of a novel family of ... Polintons encode up to 10 proteins, the key elements being the protein-primed type B DNA polymerase and the retroviral-like ... Meanwhile an overlapping class of transposable element was described under the name polintons, derived from the key proteins ...
*  KilA-N domain
... a novel class of giant transposable elements widespread in eukaryotes and related to DNA viruses". Gene. 390 (1-2): 3-17. doi: ... Putative proteins with homology to the KilA-N domain have also been identified in Maverick transposable elements of the ... It is a novel conserved DNA-binding domain is found at the N-terminus of the poxvirus D6R/NIR proteins. It is also found in a ... The KilA-N domain has been suggested to be homologous to the fungal DNA-binding APSES domain. In all proteins shown to contain ...
*  Shiladitya DasSarma
Simsek, M.; DasSarma, S.; RajBhandary, U. L.; Khorana, H. G. (1982-12-01). "A transposable element from Halobacterium halobium ... and DNA repair systems. DasSarma's recent research (2010's) on an Antarctic halophilic microorganism, Halorubrum lacusprofundi ... "High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements ... In early work (1980's), he discovered mobile genetic elements in Haloarchaea, while a graduate student with H. Gobind Khorana ( ...
*  L1
... a transposable element in DNA Volkswagen L1, a Volkswagen concept hybrid car The first lumbar vertebra of the vertebral column ...