*DNA-formamidopyrimidine glycosylase

... formamidopyrimidine-DNA glycosylase, formamidopyrimidine-DNA glycosylase, DNA-formamidopyrimidine glycosidase, Fpg protein) is ... DNA-formamidopyrimidine glycosylase (EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N ... DNA-formamidopyrimidine glycosylase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... Boiteux, S.; O'Connor, T.R.; Laval, J. (1987). "Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing ...

*Formamidopyrimidine DNA glycosylase

"Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA ... Formamidopyrimidine DNA glycosylase (FPG) is a base excision repair enzyme which recognizes and removes a wide range of ... "Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from ... oxidized purines from correspondingly damaged DNA. It was discovered by Zimbabwean scientist Christopher J. Chetsanga in 1975. ...

*H2TH domain

Examples include formamidopyrimidine-DNA glycosylases (Fpg; MutM) and endonuclease VIII (Nei). Formamidopyrimidine-DNA ... "Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA". J. Biol. Chem. 277 (22): 19811-6. doi:10.1074/ ... is a DNA-binding domain found in DNA glycosylase/AP lyase enzymes, which are involved in base excision repair of DNA damaged by ... These enzymes are primarily from bacteria, and have both DNA glycosylase activity EC 3.2.2.- and AP lyase activity EC 4.2.99.18 ...

*FPG IleRS zinc finger

Examples include formamidopyrimidine-DNA glycosylases (Fpg; MutM) and endonuclease VIII (Nei). Formamidopyrimidine-DNA ... "Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA". J. Biol. Chem. 277 (22): 19811-6. doi:10.1074/ ... DNA glycosylase/AP lyase enzymes are involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. These ... The FPG IleRS zinc finger domain represents a zinc finger domain found at the C-terminal in both DNA glycosylase/AP lyase ...

*List of MeSH codes (D08)

... dna glycosylases MeSH D08.811.074.249.500 --- DNA-formamidopyrimidine glycosylase MeSH D08.811.074.249.750 --- thymine dna ... dna glycosylases MeSH D08.811.277.450.737.099.500 --- DNA-formamidopyrimidine glycosylase MeSH D08.811.277.450.737.099.750 --- ... uracil-dna glycosidase MeSH D08.811.074.500 --- dna ligases MeSH D08.811.074.750 --- DNA-(apurinic or apyrimidinic site) lyase ... dna polymerase beta MeSH D08.811.913.696.445.308.300.225 --- dna polymerase i MeSH D08.811.913.696.445.308.300.230 --- dna ...

*FPG

... an American poetry festival Formamidopyrimidine DNA glycosylase Formosa Plastics Group, a Taiwanese conglomerate Fragmenta ...

*Christopher Chetsanga

Formamidopyrimidine DNA Glycosylase, which removes damaged 7-methylguanine from DNA (1979). DNA cyclase, which recloses ... "Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from ... Chetsanga, C.J.; Grigorian, C. (1985). "In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by ... of Biochemistry and Molecular Biology at Harvard University Discovered two enzymes involved in the repair of damaged DNA: ...

*List of EC numbers (EC 3)

DNA-3-methyladenine glycosylase II EC 3.2.2.22: rRNA N-glycosylase EC 3.2.2.23: DNA-formamidopyrimidine glycosylase EC 3.2.2.24 ... uracil-DNA glycosylase EC 3.2.2.28: double-stranded uracil-DNA glycosylase EC 3.2.2.29: thymine-DNA glycosylase EC 3.2.3.1: now ... DNA-deoxyinosine glycosylase EC 3.2.2.16: methylthioadenosine nucleosidase EC 3.2.2.17: deoxyribodipyrimidine endonucleosidase ... DNA-3-methyladenine glycosylase I EC 3.2.2.21: ... DNA helicase EC 3.6.4.13: RNA helicase EC 3.6.5.1: ...

*NTHL1

... and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA". ... 2005). "DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 ... As reviewed by Li et al., NTHL1 is a bifunctional DNA glycosylase that has an associated beta-elimination activity. NTHL1 is ... 2002). "Escherichia coli Nth and human hNTH1 DNA glycosylases are involved in removal of 8-oxoguanine from 8-oxoguanine/guanine ...

*Head and neck cancer

... and formamidopyrimidine in DNA (see image). Both 8-oxo-dG and formamidopyrimidine are mutagenic. DNA glycosylase NEIL1 prevents ... high levels of DNA amplifications, interchromosomial rearrangements, or changes in DNA methylation patterns, the latter being ... p53 prevents cell growth when DNA is damaged by activating apoptosis and p21, a kinase that blocks the formation of cyclin D / ... Kalam MA, Haraguchi K, Chandani S, Loechler EL, Moriya M, Greenberg MM, Basu AK (2006). "Genetic effects of oxidative DNA ...

*DNA glycosylase

The most abundant lesions formed at guanine residues are 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 8-oxoguanine. ... This entry represents various uracil-DNA glycosylases and related DNA glycosylases (EC), such as uracil-DNA glycosylase, ... and single-strand selective monofunctional uracil-DNA glycosylase (SMUG1). Uracil DNA glycosylases remove uracil from DNA, ... Uracil-DNA glycosylases are DNA repair enzymes that excise uracil residues from DNA by cleaving the N-glycosydic bond, ...

*Base excision repair

The reduction in the excision of methylated bases from DNA suggests an age-dependent decline in 3-methyladenine DNA glycosylase ... 6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG, FapyA) Alkylated bases: 3-methyladenine, 7-methylguanosine Deaminated bases: ... A wide variety of glycosylases have evolved to recognize different damaged bases. Examples of DNA glycosylases include Ogg1, ... This was the most frequent DNA repair abnormality found among the 8 DNA repair genes tested. NEIL1 was also one of six DNA ...