A distinct group of DNA-binding proteins are the DNA-binding proteins that specifically bind single-stranded DNA. In humans, ... is a widespread qualitative technique to study protein-DNA interactions of known DNA binding proteins. DNA-Protein-Interaction ... Also proteins that repair DNA such as uracil-DNA glycosylase interact closely with it. In general, proteins bind to DNA in the ... DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or ...
DNA-binding domain DNA-binding protein DNA-binding protein from starved cells Transcription factor Drlica K, Rouviere-Yaniv J ( ... Following elution, the protein readily binds DNA, indicating the protein's high affinity for DNA. Histone-like proteins were ... bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known ... In DNA replication at the lagging strand site, DNA polymerase III removes nucleotides individually from the DNA binding protein ...
... or UV-DDB is a protein complex that is responsible for repair of UV-damaged DNA. This complex is ... October 2012). "Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA ... Iovine B, Iannella ML, Bevilacqua MA (December 2011). "Damage-specific DNA binding protein 1 (DDB1): a protein with a wide ... DNA binds to DDB2 only when damaged by UV radiation. Binding with high affinity to a helical domain of DDB2 in the dimer form, ...
... (TDP-43, transactive response DNA binding protein 43 kDa) is a protein that in humans is encoded by ... "TARDBP TAR DNA binding protein [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2021-12-13. Qin H, Lim LZ ... Wikimedia Commons has media related to TAR DNA-binding protein 43, TDP-43. GeneReviews/NCBI/NIH/UW entry on TARDBP-Related ... February 2019). "Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology ...
The precise function of the protein domain SAND remains to be determined. Nevertheless, it is thought to be a DNA binding ... Henceforth, this suggests that the SAND domain is the DNA-binding region of DEAF-1. The structure of this protein domain ... In molecular biology, the protein domain SAND is named after a range of proteins in the protein family: Sp100, AIRE-1, NucP41/ ... Speckled protein 100 kDa), NUDR (Nuclear DEAF-1 related), GMEB (Glucocorticoid Modulatory Element Binding) proteins and AIRE-1 ...
Protein families, DNA replication, Proteins, DNA-binding substances, DNA-binding proteins). ... Single-strand DNA-binding protein (SSB) is a protein found in Escherichia coli (E. coli) bacteria, that binds to single- ... DNA-binding protein Single-stranded binding protein Comparison of nucleic acid simulation software Shishmarev D, Wang Y, Mason ... "Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined ...
Inhibitor of DNA-binding/differentiation proteins, also known as ID proteins comprise a family of proteins that heterodimerize ... ID proteins can bind E-proteins, preventing them from binding bHLH proteins and halting transcription, a case often seen in ... transcription factors to inhibit DNA binding of bHLH proteins. ID proteins also contain the HLH-dimerization domain but lack ... The first helix-loop-helix proteins identified were named E-proteins because they bind to Ephrussi-box (E-box) sequences. In ...
"Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells. A ferritin-like DNA-binding ... DNA-binding proteins from starved cells (DPS) are bacterial proteins that belong to the ferritin superfamily and are ... Chiancone E, Ceci P (January 2010). "Role of Dps (DNA-binding proteins from starved cells) aggregation on DNA". Frontiers in ... DNA-binding protein from starved cells): a study with the wild-type protein and a catalytic centre mutant". Chemistry: A ...
Zinc finger Two beta strands with an alpha helix end folded over to bind a zinc ion. Important in DNA binding proteins. Helix- ... Cruciform DNA Cruciform DNA is a form of non-B DNA that requires at least a 6 nucleotide sequence of inverted repeats to form a ... Three or four consecutive amino acid residues form a cation-binding feature. Sequence motif Short linear motif Protein tandem ... D-loop A displacement loop or D-loop is a DNA structure where the two strands of a double-stranded DNA molecule are separated ...
Wahls WP, Swenson G, Moore PD (June 1991). "Two hypervariable minisatellite DNA binding proteins". Nucleic Acids Research. 19 ( ... Wahls WP, Swenson G, Moore PD (June 1991). "Two hypervariable minisatellite DNA binding proteins". Nucleic Acids Research. 19 ( ... These hotspots are binding sites for the PRDM9 Zinc Finger array. Upon binding to DNA, PRDM9 catalyzes trimethylation of ... minisatelite binding protein 3). This would later turn out to be the same PRDM9 protein independently identified later. In 2005 ...
There are 2 main steps involved: the protein binds to a non-specific site on the DNA and then it diffuses along the DNA chain ... The in vivo model mentioned above clearly explains 3-D and 1-D diffusion along the DNA strand and the binding of proteins to ... 2013), during the process of protein sliding, the protein searches the entire length of the DNA chain using 3-D and 1-D ... Blocker proteins participate in 1-D diffusion only i.e. bind to and diffuse along the DNA contour and not in the cytosol. ...
This list covers DNA-binding proteins. For other protein-related codes, see List of MeSH codes (D12.776). Codes before these ... ccaat-enhancer-binding protein-alpha MeSH D12.776.260.108.124.750 - ccaat-enhancer-binding protein-beta MeSH D12.776.260.108. ... sterol regulatory element binding proteins MeSH D12.776.260.103.500.750.500 - sterol regulatory element-binding protein 1 MeSH ... sterol regulatory element binding proteins MeSH D12.776.260.108.092.750.500 - sterol regulatory element binding protein 1 MeSH ...
Lyons PJ, Muise AM, Ro HS (2005). "MAPK modulates the DNA binding of adipocyte enhancer-binding protein 1". Biochemistry. 44 (3 ... AE binding protein 1 is a protein that in humans is encoded by the AEBP1 gene. AE binding protein 1 is a member of ... "Entrez Gene: AE binding protein 1". Human AEBP1 genome location and AEBP1 gene details page in the UCSC Genome Browser. Tumelty ... The protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation ...
Catherine J. Murphy; Eric B. Brauns; Latha Gearheart (1996). "Quantum Dots as Inorganic DNA-Binding Proteins". MRS Proceedings ... Binding DNA to the surface of a quantum dot increases the stability of the quantum dots. The DNA chains provide more ... protein binding, and biomarkers. The ability to visualize the chemical and biological processes of DNA allows feedback to ... This results in fewer strands of DNA binding to each quantum dot. Lower ionic strength results in more stable quantum dots, but ...
... a versatile protein domain occurring in a wide variety of DNA-binding proteins". Cell. Mol. Life Sci. 64 (19-20): 2590-606. doi ... a versatile protein domain occurring in a wide variety of DNA-binding proteins". Cellular and Molecular Life Sciences. 64 (19- ... DNA-binding substances, Protein domains, All stub articles, Protein stubs). ... In molecular biology, the HMG-box (high mobility group box) is a protein domain which is involved in DNA binding. The domain is ...
A distinct group of DNA-binding proteins is the DNA-binding proteins that specifically bind single-stranded DNA. In humans, ... DNA exists in many possible conformations that include A-DNA, B-DNA, and Z-DNA forms, although only B-DNA and Z-DNA have been ... DNA at Curlie DNA binding site prediction on protein DNA the Double Helix Game From the official Nobel Prize web site DNA under ... Other non-specific DNA-binding proteins in chromatin include the high-mobility group proteins, which bind to bent or distorted ...
Patsialou A, Wilsker D, Moran E (2005). "DNA-binding properties of ARID family proteins". Nucleic Acids Research. 33 (1): 66-80 ... type winged-helix DNA-binding domain, and a conserved N-terminal AT-rich DNA interaction domain-the last domain for which the ... "Nomenclature of the ARID family of DNA-binding proteins". Genomics. 86 (2): 242-51. doi:10.1016/j.ygeno.2005.03.013. PMID ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (4): 273-81. ...
"Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: two independent DNA-binding domains ... proteins can bind to modify the protein's function. SUMO proteins may modify proteins to perform many functions, including ... a common structure in proteins that interact with DNA, including zinc-finger proteins. C8orf34 protein undergoes few ... Walter P, Roberts K, Raff M, Lewis J, Johnson A, Alberts B (2002). "DNA-Binding Motifs in Gene Regulatory Proteins". Molecular ...
... proteins have weak DNA-binding capacity. Therefore, to effectively bind DNA, NFAT proteins must cooperate with other ... This NFAT:AP-1 complex binds to the conventional Rel-family proteins DNA binding sites and is involved in gene transcription in ... Under normal circumstances the STIM proteins bind calcium ions but if most of them are released from ER the bound ions are ... This complex afterwards activates transcription of BATF which then also binds to NFAT and together with other proteins like ...
Patsialou A, Wilsker D, Moran E (2005). "DNA-binding properties of ARID family proteins". Nucleic Acids Research. 33 (1): 66-80 ... Yuan YC, Whitson RH, Liu Q, Itakura K, Chen Y (Nov 1998). "A novel DNA-binding motif shares structural homology to DNA ... a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs". Genome ... "Dynamics of the Mrf-2 DNA-binding domain free and in complex with DNA". Biochemistry. 40 (31): 9142-50. doi:10.1021/bi010476a. ...
Patsialou A, Wilsker D, Moran E (2005). "DNA-binding properties of ARID family proteins". Nucleic Acids Research. 33 (1): 66-80 ... a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs". Genome ... "Dynamics of the Mrf-2 DNA-binding domain free and in complex with DNA". Biochemistry. 40 (31): 9142-50. doi:10.1021/bi010476a. ... containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer". The Journal ...
1999). "Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with ... Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein ... 1996). "The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins". Nucleic ... "A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif". Nucleic ...
GCC box DNA-binding protein interacts with an ocs element binding protein". Proc. Natl. Acad. Sci. U.S.A. 94 (11): 5961-6. ... Ohme-Takagi M, Shinshi H (February 1995). "Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive ... ethylene-responsive+element+binding+protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e ( ... Ethylene-responsive element binding protein (EREBP) is a homeobox gene from Arabidopsis thaliana and other plants which encodes ...
CRP protein binds cAMP, which causes a conformational change that allows CRP to bind tightly to a specific DNA site in the ... CRP binds to a DNA site that overlaps the promoter -35 element and activates transcription through two sets of protein-protein ... CRP binds to a DNA site located upstream of core promoter elements and activates transcription through protein-protein ... Lawson CL, Swigon D, Murakami KS, Darst SA, Berman HM, Ebright RH (2004). "Catabolite activator protein: DNA binding and ...
DNA helicases, DNA clamps and DNA topoisomerases, and replication proteins; e.g. single-stranded DNA binding proteins (SSB). In ... Clamp proteins act as a sliding clamp on DNA, allowing the DNA polymerase to bind to its template and aid in processivity. The ... All these control the binding of initiator proteins to the origin sequences. Because E. coli methylates GATC DNA sequences, DNA ... To prevent this, single-strand binding proteins bind to the DNA until a second strand is synthesized, preventing secondary ...
Schreiber J, Enderich J, Wegner M (May 1998). "Structural requirements for DNA binding of GCM proteins". Nucleic Acids Res. 26 ... in the process of DNA binding and in the redox regulation of DNA binding. The GCM domain as a new class of Zn-containing DNA- ... binding domain with no similarity to any other DNA-binding domain. The GCM domain consists of a large and a small domain ... Akiyama Y, Hosoya T, Poole AM, Hotta Y (December 1996). "The gcm-motif: a novel DNA-binding motif conserved in Drosophila and ...
The BolA protein is a DNA-binding regulator; the Fra2 protein is an iron sulfur cluster protein that binds Grx3/4 and is ... In molecular biology, the BolA-like protein family consists of the morpho-protein BolA from Escherichia coli, the Fra2 protein ... It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5. Dressaire C, Moreira ... This article incorporates text from the public domain Pfam and InterPro: IPR002634 (Protein families). ...
Červenák F, Juríková K, Nosek J, Tomáška L (2017). "Double-stranded telomeric DNA binding proteins: Diversity matters". Cell ... Protein complexes, Telomere-binding proteins, Telomere-related proteins). ... TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded TTAGGG region of the ... RAP1 (Repressor / Activator Protein 1): RAP1 is a stabilizing protein associated with TRF2. RAP1 inhibits DNA repair. POT1 ( ...
Protein pages needing a picture, DNA-binding proteins). ... The proteins are known to pack DNA more tightly than histones ... DNA-binding nucleoproteins found exclusively in dinoflagellates and Nucleocytoviricota. It serves to compact DNA in these ... "Loss of nucleosomal DNA condensation coincides with appearance of a novel nuclear protein in dinoflagellates". Current Biology ... This action is thought to be one of the driving forces for dinoflagellates to switch to this protein instead of histone for ...
... they are part of a DNA sequence (e.g. a genome) and (2) they are bound by DNA-binding proteins. DNA binding sites are often ... DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from ... that are specifically bound by one or more DNA-binding proteins or protein complexes. It has been reported that some binding ... To quantify the binding affinity of proteins and other molecules to specific DNA binding sites the biophysical method ...
Wan, Fengyi; Lenardo, Michael J. (2009-10-01). "Specification of DNA Binding Activity of NF-κB Proteins". Cold Spring Harbor ... His post-doctoral training was productive and involved developing the functional assay for the newly described NF-kB binding ... In Donelson's laboratory, Lenardo was introduced to advanced molecular techniques, including DNA manipulation and sequencing, ... Early-Onset Protein-Losing Enteropathy, and Thrombosis". New England Journal of Medicine. 377 (1): 52-61. doi:10.1056/ ...