"Langerhans Cell Histiocytosis". NORD (National Organization for Rare Disorders). Retrieved 5 December 2020. Stanway, Amy (2005 ... Chronic multifocal Langerhans cell histiocytosis, previously known as Hand-Schüller-Christian disease, is a type of Langerhans ... "Histiocytosis X", where "X" denoted the then unknown cause. It is now known as chronic multifocal Langerhans cell histiocytosis ... "Langerhans cell histiocytosis , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". rarediseases.info.nih. ...
"Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders". The ... Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells, abnormal cells deriving from bone ... was diagnosed with Langerhans cell histiocytosis.[citation needed] Langerhans cell histiocytosis is occasionally misspelled as ... "Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version". Langerhans Cell Histiocytosis Treatment (PDQ®). ...
Weitzman S, Jaffe R (September 2005). "Uncommon histiocytic disorders: the non-Langerhans cell histiocytoses". Pediatr Blood ... Non-Langerhans cell histiocytosis refers to a family of histiocytosis characterized by the absence of Langerhans cells. Many ... The spectrum of non-langerhans cell histiocytoses include: Benign cephalic histiocytosis Generalized eruptive histiocytoma ... "Non-Langerhans-Cell Histiocytosis". NIH. The Genetic and Rare Diseases Information Center (GARD). Retrieved 19 March 2019. ...
In general, the cause of Langerhans Cell Histiocytosis is unknown. Regardless of the subtype of Langerhans cell histiocytosis, ... Shahlaee, A. H. and Arceci, R. J. (2006). Histiocytic disorders, in Pediatric hematology (3rd ed.). Malden, Mass.: Blackwell ... Lipton, J. M.; Levy, C. F. (December 2021). "Langerhans Cell Histiocytosis - Hematology and Oncology". Merck Manuals ... Electron microscopy will show racket-like Langerhans cell granules within the specific infiltrating cells. The demonstration of ...
Tran, Gary; Huynh, Thy N.; Paller, Amy S. (March 2018). "Langerhans cell histiocytosis: A neoplastic disorder driven by Ras-ERK ... Kumar, Neeta; Sayed, Shahin; Vinayak, Sudhir (2011-01-20). "Diagnosis of Langerhans cell histiocytosis on fine needle ... Kobayashi, Masayuki; Tojo, Arinobu (December 2018). "Langerhans cell histiocytosis in adults: Advances in pathophysiology and ... "Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies". Cancer ...
The most common histiocyte disorders are Langerhans' cell histiocytosis and haemophagocytic lymphohistiocytosis. Histiocytosis ... Langerhans cells are antigen-presenting cells but have undergone further differentiation. Skin Langerhans cells express CD1a, ... Some sources consider Langerhans cell derivatives to be histiocytes. The Langerhans cell histiocytosis embeds this ... A subset of cells differentiates into Langerhans cells; this maturation occurs in the squamous epithelium, lymph nodes, spleen ...
... is a condition that is a self-limited form of Langerhans cell histiocytosis.: 720 ... This is suspected of being a genetic disorder, and as the name implies, is self healing. Skin: Commonly seen are a rash which ... ISBN 978-0-7216-2921-6. "Langerhans Cell Histiocytosis - Patient UK". Retrieved 2007-05-10. John Thorne Crissey; Lawrence C. ... Lymph node: Enlargement of the lymph nodes in 50% of Histiocytosis cases. It was first described by Ken Hashimoto and M. S. ...
Online Mendelian Inheritance in Man (OMIM): Langerhans cell histiocytosis - 604856 Langerhans Cell Histiocytosis at eMedicine ... hematopoietic origin for the disorder. LCH can cause damage to skin, bone and other organs.[citation needed] Langerhans cells ... In the rare disease Langerhans cell histiocytosis (LCH), an excess of cells similar to these cells are produced. However LCH ... A Langerhans cell (LC) is a tissue-resident macrophage of the skin once thought to be a resident dendritic cell. These cells ...
Systemic disorders may be localized in the vulvo-perineal region. In Langerhans cell histiocytosis, lesions initially are ... Acrodermatitis enteropathica is a biochemical disorder of zinc metabolism. Diaper dermatitis in infancy Epidermal cysts ... Dominique Hamel-Teillac sara catanzaro (2005). "Vulvo-Perineal Localization of Dermatologic Disorders, 2005". Health.am. ...
... "non-Langerhans cell histiocytosis", or more specifically, "type 2". It is a rare skin disorder that primarily affects children ... JXG is a benign idiopathic cutaneous granulomatous tumor and the most common form of non-Langerhans cell histiocytosis (non-LHC ... Histiocytic disorders like JXG are identified by the cells that make them up. Immunohistochemical analysis is used to discern ... group of disorders defined by the accumulation of histiocytes that do not meet criteria to be diagnosed as Langerhans cells. ...
Examples include Langerhans cell histiocytosis.: 35 Bruxism, which is an abnormal repetitive movement disorder characterised by ... "Bruxism in Movement Disorders: A Comprehensive Review: Bruxism in Movement Disorders". Journal of Prosthodontics. 26 (7): 599- ... Dholam, Kp; Chouksey, Gc (2016). "Squamous cell carcinoma of the oral cavity and oropharynx in patients aged 18-45 years: A ... Oral cancer is a malignant abnormal excessive growth of cells within the oral cavity, which arises from premalignant lesions ...
Langerhans cell histiocytosis, and 46,XY disorders of sex development. E6201 is an enzyme inhibitor of MAP3K1 that shows cross- ... June 2015). "MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis". Genes, Chromosomes & Cancer. 54 (6): 361-368. doi: ... Genetics has revealed that MAP3K1 is important in: embryonic development, tumorigenesis, cell growth, cell migration, cytokine ... embryonic stem cells, and the DT40 cell line to identify genetic traits. MAP3K1 contains multiple amino acid sites that are ...
Langerhans cell histiocytosis and hepatic hemangioma a benign tumour the most common type of liver tumour, thought to be ... In the disorders of cirrhosis and portal hypertension, the umbilical vein can open up again. The various functions of the liver ... sinusoidal endothelial cells, and phagocytic Kupffer cells. Hepatic stellate cells are nonparenchymal cells found in the ... The Kupffer cells of liver are phagocytic cells, helps in phagocytosis of dead blood cells and bacteria from the blood. The ...
Langerhans cell histiocytosis (LCH): LCH is an aggressive disorder due to proliferation of Langerhans cell hystiocytes, and the ... The dentate nucleus is a cluster of neurons, or nerve cells, in the central nervous system that has a dentate - tooth-like or ... The upper part of the cell body is parallel to the apical dendrites, which are oriented toward the nuclear core. Small local ... During this time, the neurons of the dentate nucleus are similar in shape and form, being mainly bipolar cells. During 22-28 ...
Non-Langerhans-Cell Histoplasmosis Histrionic personality disorder Hittner-Hirsch-Kreh syndrome HIV Hm syndrome HMG-CoA lyase ... bundle tachycardia Histadelia Histapenia Histidinemia Histidinuria renal tubular defect syndrome Histiocytosis X Histiocytosis ... cluster Hearing disorder Hearing impairment Hearing loss Heart aneurysm Heart attack Heart block progressive, familial Heart ... Hallucinogen persisting perception disorder Hallux valgus Hamanishi-Ueba-Tsuji syndrome Hamano-Tsukamoto syndrome Hamartoma ...
... pulmonary Langerhans cell histiocytosis: lymphangioleiomyomatosis, neurofibromatosis, vasculitis Metabolic disorders: glycogen ... It acts on the endothelin receptors ETA and ETB in various cell types including vascular smooth muscle cells and fibroblasts, ... This nitric oxide diffuses into neighboring cells (including vascular smooth muscle cells and platelets), where it increases ... Prostacyclin is synthesized from arachidonic acid in endothelial cells. In vascular smooth muscle cells, prostacyclin binds ...
Although part of normal Langerhans cell histology, they also provide a mechanism to differentiate Langerhans cell histiocytoses ... which are a group of rare conditions collectively known as histiocytoses) from proliferative disorders caused by other cell ... "Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function". Mol. Cell ... "An electron microscope study of basal melanocytes and high-level clear cells (Langerhans cells) in vitiligo". Journal of ...
Down syndrome Leukocyte adhesion deficiency disorder Papillon-Lefèvre syndrome Chédiak-Higashi syndrome Langerhans cell disease ... histiocytosis syndromes) Glycogen storage disease Chronic granulomatous disease Infantile genetic agranulocytosis Cohen ... Associated with hematologic disorders: Acquired neutropenia Leukemia For those patients with periodontitis as a manifestation ... as PDF Archived 2010-11-28 at the Wayback Machine (Webarchive template wayback links, Periodontal disorders). ...
T-cell lymphomas multiple myeloma Waldenström's macroglobulinemia Wiskott-Aldrich syndrome Langerhans cell histiocytosis (LCH) ... these cause B cell lymphoproliferative disorders; however, some T cell variations have been described. The T cell variations ... A mutation on the X chromosome is associated with a T cell and natural killer cell lymphoproliferative disorder.[citation ... The two major types of lymphocytes are B cells and T cells, which are derived from pluripotent hematopoietic stem cells in the ...
Pulmonary Langerhans cell histiocytosis Pulmonary lymphangioleiomyomatosis Honeycomb lung caused by idiopathic pulmonary ... Tuberculosis Chlamydia trachomatis Respiratory syncytial virus Lymphangitic carcinomatosis Diffuse developmental disorders ... proteinosis Sarcoidosis Pulmonary veno-occlusive disease Upper lung predominance Pulmonary Langerhans cell histiocytosis ... Chronic eosinophilic pneumonia Cryptogenic organizing pneumonia Lymphoproliferative disorders Pulmonary alveolar proteinosis ...
Langerhans cells are dendritic cells found in the skin and function by internalizing antigens (foreign particles) and ... Histiocytic disorders refer to diseases that are caused by abnormal behavior of these cells. They include the following: ... Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M (2006). "Langerhans cells arise ... Reactive diseases of Langerhans cells (most important feature in immune histochemistry is expression of E-cadherin) ...
... due to malignancy of mesenchymal cells that have failed to fully differentiate into muscle cells Langerhans cell histiocytosis ... Disorders of elastic tissue". Weedon's Skin Pathology Essentials (2nd ed.). Elsevier. p. 763. ISBN 978-0-7020-6830-0. Archived ... Some types of cancers can cause it such as rhabdomyosarcoma, extrosseal Ewing sarcoma, Langerhans cell histiocytosis, ... Condition due to excess build-up of Langerhans cells. Lupus: autoimmune disease Diagnosis of the medical condition is based on ...
... granular cell tumor, Langerhans cell histiocytosis, fibrous histiocytoma, xanthogranuloma, Gaucher's disease, malakoplakia, and ... The majority of patients (90%) are diagnosed with crystal-storing histiocytosis had a neoplastic B-cell disorder - most ... Histiocytosis is an excessive number of histiocytes (an immune cell type which is part of the mononuclear phagocyte system). In ... Crystal-storing histiocytosis is a rare disorder, with less than 100 cases found in the scientific literature. The median age ...
Nonhereditary recurrent pneumothorax and/or pulmonary cysts can occur with Langerhans cell histiocytosis and ... The disorder has been reported in more than 100 families worldwide, though some sources cite up to 400 families, and it is ... it is associated with clear cell renal cell carcinoma and papillary renal cell carcinoma. If it develops in someone with BHD, ... clear cell renal cell carcinoma), hereditary papillary renal cancer (papillary renal cell carcinoma), and hereditary ...
They include the following: Reactive diseases of Langerhans cells Histiocytomas Cutaneous histiocytosis Systemic histiocytosis ... Histiocytic disorders refer to diseases that are caused by abnormal behavior of these cells. ... A similar disease in humans, Hashimoto-Pritzker disease, is also a Langerhans cell histiocytosis. Dog breeds that may be more ... Langerhans cells are dendritic cells found in the skin and function by internalizing antigens (foreign particles) and ...
Langerhans cell histiocytosis etc.) Leukaemia Autoimmune - associated with thyroiditis Other rare causes which include ... The disorder is treated with vasopressin analogs such as desmopressin. Nonetheless, many times desmopressin alone is not enough ... Pituitary Gland Disorders: Merck Manual Home Health Handbook". Retrieved 2009-04-04. "Familial Neurogenic Diabetes Insipidus: a ... hemochromatosis and histiocytosis. Vasopressin is released by the posterior pituitary, but unlike most other pituitary hormones ...
Langerhans Cell Histiocytosis". In Ansell SM (ed.). Rare Hematological Malignancies. Springer Science & Business Media. p. 383 ... Egan C, Jaffe ES (January 2018). "Non-neoplastic histiocytic and dendritic cell disorders in lymph nodes". Seminars in ... Histiocytosis (and malignant histiocytosis) are both important in veterinary as well as human pathology. Histiocytosis is a ... According to the Histiocytosis Association, 1 in 200,000 children in the United States are born with histiocytosis each year. ...
Histologically, ECD differs from Langerhans cell histiocytosis (LCH) in a number of ways. Unlike LCH, ECD does not stain ... Histiocytosis, Skeletal disorders, Syndromes affecting blood, Diseases named for discoverer). ... a non-Langerhans-cell histiocytosis, with interferon-alpha". Blood. 106 (9): 2992-2994. doi:10.1182/blood-2005-06-2238. PMID ... Langerhans Cell Histiocytosis, and Rosai-Dorfman Disease". Mayo Clinic Proceedings. 94 (10): 2054-2071. doi:10.1016/j.mayocp. ...
The exact mechanism of action is unknown but it does have effects on the Langerhans cells in the epidermis. Grenz rays are ... Grenz Ray Therapy for Skin Disorders Grenz Rays (Articles with short description, Short description matches Wikidata, ... Hailey-Hailey disease and histiocytosis X. Grenz rays have also been used for treatment of actinic keratosis and Bowen's ... Lindelof B, Linden S, Ros A-M Effect of Grenz rays on Langerhans cells in human epidermis.Acta Dermatol.Venereol (Stockh)64:436 ...
B-cell lymphoma, T-cell lymphomas, T cell leukemias, and Langerhans cell histiocytosis. Other hematological diseases are ... Forced expression of this fusion protein in mice causes a fatal mixed myeloid and/or T-cell lymphoproliferative disorder. BCR ... Hematopoietic stem cells give rise to: 1) myeloid precursor cells that differentiate into red blood cells, mast cells, blood ... Similar non-clonal eosinophilia due to eosinophil precursor cell stimulation by clonal malignant cells is sometimes seen in ...