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*  HIV disease progression rates
Rapid progression was originally thought to be continent specific, as some studies reported that disease progression is more ... 1999). "Human immunodeficiency virus type 1 subtypes differ in disease progression". Journal of Infectious Diseases. 179 (1): ... Morgan, D.; G.H. Maude; S.S. Malamba; M.J. Okongo; H.U. Wagner; D.W. Mulder; J.A. Whitworth (1997). "HIV-1 disease progression ... Another subset of individuals who are persistently infected with HIV-1, but show no signs of disease progression for over 12 ...
*  SMAD (protein)
Eddy AA, Neilson EG (November 2006). "Chronic kidney disease progression". Journal of the American Society of Nephrology. 17 ( ... Smad3 knockout mice display reduced progression of renal fibrosis, suggesting its importance in regulating the disease. ... In adult cells, TGF-B inhibits cell cycle progression, stopping cells from making the G1/S phase transition. This phenomenon is ... This loss of TGF-B inhibition results in increased amounts of active Smad2/3, which contribute to the progression of renal ...
*  TRG (gene)
Correlation with disease progression?". Tumori. 94 (3): 384-8. PMID 18705407. Chen M, Zhang D, Zhen W, Shi Q, Liu Y, Ling N, ... The Journal of Infectious Diseases. 198 (11): 1643-50. doi:10.1086/593065. PMID 18954265. Perko R, Kang G, Sunkara A, Leung W, ... "T-gammadelta receptor restriction in peripheral lymphocytes of patients with Beh├žet's disease". Advances in Experimental ...
*  Li-Huei Tsai
"Epigenomics of Alzheimer's disease progression". MIT News. Retrieved 2017-03-21. Gjoneska, Elizabeta; Pfenning, Andreas R.; ... for her research on Alzheimer's disease and the role of CDK5 and chromatin remodeling in the progression of the disease. Born ... In recent work, Tsai has elucidated the role of structural and epigenetic mechanisms in Alzheimer's disease, showing in two ... Journal of Alzheimer's disease: JAD. 56 (1): 335-349. doi:10.3233/JAD-160916. ISSN 1875-8908. PMID 28085018. Roberts, Michelle ...
*  Benign symmetric lipomatosis
... abstinence from alcohol prevents disease progression. Defects in the adrenergic-stimulated lipolysis and accumulation of ... The appearance of people with the disease is depicted in: Carvings of Queen of Punt (Egypt), as noted above The Italian statue ... Medappil Noushif; Vasu TA (July 2010). "Madelung's disease: A spot diagnosis". Indian J Plast Surg. 43 (2): 227-8. doi:10.4103/ ... The cause of the disease remains unknown, but its incidence strongly correlates with alcohol abuse; ...
*  Selenium yeast
Selenium status diminishes with HIV disease progression; low selenium status has been shown to be a predictor of HIV-related ... Certain viral diseases have been shown to mutate more rapidly in selenium-deficient hosts producing more virulent viruses. This ... the importance of selenium status in the incidence and progression of a variety of infectious and degenerative diseases. Cancer ... Daily supplementation was found to suppress progression of HIV-1 viral burden and provide indirect improvement to CD4 cell ...
*  Mesangial cell
Mechanisms of Renal Disease Progression". Experimental Biology and Medicine. 233 (1): 4-11. doi:10.3181/0705-MR-134. PMID ... Scindia, Y; Deshmukh, U; Bagavant, H (2010). "Mesangial pathology in glomerular disease: targets for therapeutic intervention ... cell proliferation and the production of extracellular matrix which can then accumulate and lead to glomerular disease. ... and accumulation of advanced glycosylation end products responsible for enhancing the risk of developing glomerular diseases. ...
*  Post-translational modification
... and disease progression". Journal of Cellular and Molecular Medicine. 10 (2): 389-406. doi:10.1111/j.1582-4934.2006.tb00407.x. ...
*  Retinitis pigmentosa
The progression of disease symptoms occurs in a symmetrical manner, with both the left and right eyes experiencing symptoms at ... The efficiency of various supplements, such as Vitamin A, DHA, and Lutein, in delaying disease progression remains an ... stalling disease progression in some patients. Recent investigations have shown that proper vitamin A supplementation can ... "Retinitis pigmentosa and allied diseases: Numerous diseases, genes, and inheritance patterns". Human Molecular Genetics. 11 (10 ...
*  Phenethyl isothiocyanate
Disease Progression and Chemoprevention: 109-126. Wang, LG; Chiao, JW (2010). "Prostate cancer chemopreventive activity of ...
*  Common root rot (barley)
Stack, R.W. (1980). "Disease progression in common rot of spring wheat and barley" (PDF). Canadian Journal of Plant Pathology. ... Stack, R.W. (1981). "Disease progression in common root rot" (PDF). Canadian Journal of Plant Pathology. 3: 184. doi:10.1080/ ... Kidambi, R.D.; A.L. Lutz; N.K. Van Alfen (1985). "Disease progress and epidemiology of crown rot of spring barley in Utah" (PDF ... Disease inoculum is reduced by long rotations with nonhost crops. Shallow seeding and optimum fertilization levels, especially ...
*  Phytophthora ramorum
The disease is capable of killing some hosts, such as rhododendron, but most survive. Disease progression on these species is ... Phytophthora ramorum is the oomycete plant pathogen known to cause the disease sudden oak death (SOD). The disease kills oak ... and instead adopted a strategy of containing the disease to reduce its spread. Symptoms of the disease on larch trees include ... In tanoaks, the disease may be recognized by wilting new shoots, older leaves becoming pale green, and after a period of two to ...
*  Posterior cingulate
Raj, A; Kuceyeski A; Weiner M (2012). "A network diffusion model of disease progression in dementia". Neuron. 73: 1204-15. doi: ... a risk factor associated with the disease). It has been found that neurodegenerative diseases spread 'prion-like' through the ... In Alzheimer's disease, the metabolic abnormality is linked to Amyloid deposition and brain Atrophy with a spatial distribution ... In Alzheimer's disease, the topology of white matter connectivity helps in predicting atrophic patterns, which could explain ...
*  Silicosis
Lung zone involvement and profusion increases with disease progression. In advanced cases of silicosis, large opacity (> 1 cm) ... The disease is caused by deposition of this dust in the lung. Desert lung disease may be related to Al Eskan disease, a lung ... "Diseases associated with exposure to silica and nonfibrous silicate minerals. Silicosis and Silicate Disease Committee". Arch. ... In: Interstitial Lung Disease. 4th ed. London: BC Decker Inc. 2003, pp391. "Silicosis Fact Sheet". World Health Organization. ...
*  Afatinib
Ebos, JM; Kerbel, RS (1 March 2011). "Antiangiogenic therapy: impact on invasion, disease progression, and metastasis". Nature ... Fall 2010 interim results suggested the drug extended progression-free survival threefold compared to placebo, but did not ... Triples Progression Free Survival in Phase III Study in Lung Cancer Patients". BusinessWire. 11 October 2010. Miller VA, Hirsh ... Keratitis Interstitial lung disease Like lapatinib and neratinib, afatinib is a protein kinase inhibitor that also irreversibly ...
*  Translocator protein
Airas L, Rissanen E, Tuisku J, Rinne J (April 2015). "Microglial Activation Correlates with Disease Progression in Multiple ... Higher levels of TSPO are present in those with heart disease, a change that is more common in men than women because ... Oxidative stress is a strong contributing factor to cardiovascular disease, and often occurs because of inflammation caused by ... Batarseh A, Papadopoulos V (2010). "Regulation of translocator protein 18 kDa (TSPO) expression in health and disease states" ( ...
*  Nusinersen
In clinical trials, the drug halted the disease progression. In around 60% of infants affected by type 1 spinal muscular ... Katie Thomas (December 30, 2016). "Costly Drug for Fatal Muscular Disease Wins F.D.A. Approval". New York Times. Grant, Charley ... Wadman, Meredith (23 December 2016). "Updated: FDA approves drug that rescues babies with fatal neurodegenerative disease". ...
*  HLA-A11
Roger M (June 1998). "Influence of host genes on HIV-1 disease progression". FASEB J. 12 (9): 625-32. PMID 9619442. Chu PG, ... A11 is also part of a haplotype A11-Cw4-B35-DR1-DQ1 that is a second factor in the rapid progression of HIV. The involvement of ... In autoimmune hepatitis, A11 has a synergistic effect, acting together with DR4 and DR3 to increase the odds of disease to over ... permanent dead link] Forbes JF, Morris PJ (May 1972). "Analysis of HL-A antigens in patients with Hodgkin's disease and their ...
*  Stiff person syndrome
Late in the disease's progression, hypnagogic myoclonus can occur. Tachycardia and hypertension are sometimes also present. ... The progression of SPS depends on whether it is a typical or abnormal form of the condition and the presence of comorbidities. ... As the disease progresses, patients sometimes become unable to walk or bend. Chronic pain is common and worsens over time but ... It takes an average of six years after the onset of symptoms before the disease is diagnosed. There is no evidence-based ...
*  Glaucoma
If treated early it is possible to slow or stop the progression of disease with medication, laser treatment, or surgery. The ... Varma R, Peeples P, Walt JG, Bramley TJ (February 2008). "Disease progression and the need for neuroprotection in glaucoma ... Sometimes, the disease appears very rapidly, especially after cataract surgery procedures. A new treatment for this disease, as ... The disease affects about 2 million people in the United States. It occurs more commonly among older people. Closed-angle ...
*  Nodular lymphocyte predominant Hodgkin's lymphoma
Diagnosis usually occurs at an early stage of disease progression. A treatment guide provided by NCCN Guidelines for Patients ... Stage IV disease is very rare. There is a male predominance of NLPHL diagnosis. B symptoms may be uncommon. ... Studies indicate that radiation therapy (radio therapy) may reduce the risk of progression in adults. In one study, stage I-II ... R-CHOP optionally followed by radiation therapy is recommended in newly diagnosed late stage disease, while for early stage ...
*  Pathophysiology of multiple sclerosis
These antibodies patterns can be used to monitor disease progression. Finally, a promising biomarker under study is an antibody ... 2016). "Cerebrospinal fluid lactate is associated with multiple sclerosis disease progression". Journal of Neuroinflammation. ... "Transcranial brain sonography findings predict disease progression in multiple sclerosis". Neurology. 73 (13): 1010-7. doi: ... Currently it is unknown what the primary cause of MS is and, if MS turns out to be a heterogeneus disease, the lesion ...
*  Helminthiasis
"Deworming helminth co-infected individuals for delaying HIV disease progression". Cochrane Database of Systematic Reviews. doi: ... Another 20 million have severe consequences from the disease. It is the most deadly of the neglected tropical diseases. Kato ... 2014). "The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases". PLOS ... "A research agenda for helminth diseases of humans: the problem of helminthiases". PLOS Neglected Tropical Diseases. 6 (4): ...
*  Ventriculitis
The progression of the disease is also largely dependent on the nature of the specific case. Depending on the underlying ... Patients often present with headaches, painful cranial pressure, and neck pain early in the progression of the disease. ... Lysozyme in Ventriculitis: A Marker for Diagnosis and Disease Progression. Journal of Neurology, Neurosurgery, and Psychiatry. ... There is also a lot of attention being paid to possible treatments and prevention methods to help make this disease even less ...
*  Serosorting
2004). "Dual HIV-1 infection associated with rapid disease progression". Lancet. 363 (9049): 619-622. doi:10.1016/S0140-6736(04 ... Centers for Disease Control and Prevention. 31 March 2009. Retrieved 2010-12-26. Golden, MR; Stekler, J; Hughes, JP; Wood, RW ( ... In addition, testing negative for HIV does not guarantee that they are free of other sexually transmitted diseases (STDs) such ... Furthermore, dual infection has been associated with a more rapid progression towards developing AIDS. Studies have shown that ...
*  Prostaglandin-endoperoxide synthase 2
It sticks platelets together and promotes clotting; inhibiting this helps prevent heart disease. On the other hand, PTGS2 (COX- ... which in turn can stimulate cancer progression. Consequently, inhibiting PTGS2 (COX-2) may have benefit in the prevention and ... Minghetti L, Pocchiari M (2007). "Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases". Int. Rev. ... Mechanisms of COX-2 inhibitor risk to heart disease". Life Sciences. 88 (1-2): 24-30. doi:10.1016/j.lfs.2010.10.017. PMC ...