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*  Adjuvant therapy
In 1995 a multicenter study reported improved long-term and disease-free survival in melanoma patients using interferon alpha ... It has been known for at least 30 years that adjuvant chemotherapy increases the relapse-free survival rate for patients with ... The aim of adjuvant treatment is to improve disease-specific symptoms and overall survival. Because the treatment is ... approved interferon alpha 2b for melanoma patients who are currently free of disease, to reduce the risk of recurrence. Since ...
*  Exemestane
... that adding everolimus to exemestane therapy against advanced breast cancer can significantly improve progression-free survival ... Exemestane is also indicated for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed ... 2007). "Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): ...
*  Microtransplantation
The 2-year probability of disease-free survival (DFS) was significantly higher in the G-PBSC group than in the control group ( ... The 6-year leukemia-free survival (LFS) and overall survival (OS) rates were 84.4% and 89.5%, respectively, in the low-risk ... Microtransplantation(MST) is an advanced technology to treat malignant hematological diseases and tumors by infusing patients ... Practices of microtransplantation has shown none graft-versus-host disease (GVHD) till present, thus immunosuppressive drugs ...
*  Acute erythroid leukemia
AEL patients did have a significantly shorter disease free survival period, a median of 32 weeks, but this effect was explained ... A 2010 study of 124 patients found a median overall survival of 8 months. A 2009 study on 91 patients found a median overall ... survival for erythroleukemia patients of 36 weeks, with no statistically significant difference to other AML patients. ... leukemia as defined in the World Health Organization classification is a rare and pathogenetically heterogeneous disease". Mod ...
*  Renal cell carcinoma
These have the advantage of being less of a burden for the patient and the disease-free survival is comparable to that of open ... and overall disease free rates are not as good as those obtained with surgical removal. Surgery for metastatic disease: If ... Average survival time in 2008 for the metastatic form of the disease was under a year and by 2013 this improved to an average ... von Hippel-Lindau disease and sickle cell disease. The most significant disease affecting risk however is not genetically ...
*  Clinical endpoint
... the curve for the actual survival would look better than disease free survival curve. The Progression Free Survival is usually ... The disease free survival is usually used to analyze the results of the treatment for the localized disease which renders the ... Just as in the survival curves not all patients die, in "disease-free survival curves" not all patients relapse and the curve ... patient apparently disease free, such as surgery or surgery plus adjuvant therapy. In the disease-free survival, the event is ...
*  MicroRNA
"High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer ... showing the value of accurate disease response measures. Cell-free miRNA are highly stable in blood, are overexpressed in ... The first human disease known to be associated with miRNA deregulation was chronic lymphocytic leukemia. Many other miRNAs also ... The first human disease associated with deregulation of miRNAs was chronic lymphocytic leukemia. Under a standard nomenclature ...
*  TOP1
"MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon ... to FU/LV in the treatment protocol resulted in MRE11-deficient patients having better long-term disease free survival than ... Higher expression of TOP1 in KRAS mutant non-small cell lung cancer and correlation to survival suggests that TOP1 inhibitors ... Irinotecan was more strongly beneficial for patients with hypermethylated WRN promoters (39.4 months survival) than for those ...
*  Type I topoisomerase
"MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon ... The 5' end is then free to rotate, twisting it about the other strand, to relax DNA until the topoisomerase religates the ...
*  XB130
... expression is significantly correlated with the survival time and disease-free period in gastric cancer patients. XB130 ... XB130 has been demonstrated to play a role in cell proliferation and survival through the regulation of the PI3K/Akt signaling ... XB130 regulates cell proliferation, cell survival, cell motility and gene expression. XB130 is highly similar to AFAP and is ... This interaction leads to the subsequent activation of Akt, cell proliferation, and cell survival. Activated Akt promotes cell ...
*  Cure
In complex diseases, such as cancer, researchers rely on statistical comparisons of disease-free survival (DFS) of patients ... is determined by comparing disease-free survival of treated people against a matched control group that never had the disease. ... Eradication of infectious diseases List of incurable diseases Preventive medicine Relapse, the reappearance of a disease ... Generally, the survival curves are adjusted for the effects of normal aging on mortality, especially when diseases of older ...
*  Vaccinogen
The study found a significant improvement in survival (p=0.02) and disease-free survival (p=0.039) in all eligible colon cancer ... in clinical outcomes between the treatment arms however there was a trend towards disease-free survival and overall survival ... In the process they tracked event-free survival for the study population out to 15 years, finding a hazard ratio for the ... The Primary Endpoint in this study is the Disease-Free Interval. Vaccinogen plans to conduct a pilot program in parallel with ...
*  Hepatoblastoma
... disease-free survival rate in the range of 80%, in cases of complete tumor removal and adjuvant chemotherapy survival rates ... The disease is most commonly diagnosed during a child's first three years of life. Alpha-fetoprotein (AFP) levels are commonly ... As a result, disease is often advanced at diagnosis. Hepatoblastomas originate from immature liver precursor cells, usually ...
*  CXCR4
CXCL12 expression is positively correlated with disease free (metastasis free) survival. CXCL12 (over-)expressing cancers might ... "CXCL12/SDF1 expression by breast cancers is an independent prognostic marker of disease-free and overall survival". European ...
*  Bendamustine
After trial results released in June 2012 showed that it more than doubled disease progression-free survival when given along ... Only free bendamustine is active. Elimination is biphasic with a half-life of 6-10 minutes and a terminal half-life of ... Rediscovered' Lymphoma Drug Helps Double Survival: Study". June 3, 2012. Archived from the original on July 12, 2012. Tageja N ... East German investigators found that it was useful for treating chronic lymphocytic leukemia, Hodgkin's disease, non-Hodgkin's ...
*  Graft-versus-host disease
"Effect of graft-versus-host disease prophylaxis on 3-year disease-free survival in recipients of unrelated donor bone marrow (T ... In a multi-center study, disease-free survival at 3 years was not different between T cell-depleted and T cell-replete ... long-term survival). While donor T-cells are undesirable as effector cells of graft-versus-host-disease, they are valuable for ... increases the risk of autoimmune disease. A GVHD-like disease called thymoma-associated multiorgan autoimmunity (TAMA) can ...
*  CA-125
... with the duration of disease-free survival correlating with the rate of fall of CA-125) and for predicting a patient's ... This is because the persistence of high levels of CA-125 during therapy is associated with poor survival rates in patients. ... Indeed, a rising CA-125 level may precede clinical evidence of disease relapse by an interval of 3 to 6 months. Prognosis ... Gupta D, Lis CG (2010). "Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the ...
*  List of MeSH codes (N05)
... survival analysis MeSH N05.715.360.750.795.300 --- disease-free survival MeSH N05.715.360.775 --- epidemiologic study ...
*  Tegafur/uracil
... improved disease free survival and/or overall survival. The UFT combination was developed in Japan during the 1980s. UFT is ...
*  Head and neck squamous-cell carcinoma
The 5 year disease free survival rate for HPV positive cancer is significantly higher when appropriately treated with surgery, ... Treatment for HNSCC is predominantly based on the stage of the disease. Factors such as patient fitness, baseline swallow, ...
*  Milan criteria
... selecting cases for transplantation according to specific strict criteria led to improved overall and disease-free survival at ... Depending on the treatment algorithm, additional factors such as advanced liver disease (as classified by Child-Pugh score) or ... reported experience at the University of California San Fransisco 5-year post-transplantation survival of 75% in patients with ... Child-Pugh score Model for End-Stage Liver Disease Mazzaferro, Vincenzo; Regalia, Enrico; Doci, Roberto; Andreola, Salvatore; ...
*  DFS
Lyons Disease-free survival, a measure of the efficacy of medical treatment Duty-free shop, retail outlets that are exempt from ... Duty Free Shoppers), a Hong Kong-based retailer operating duty-free shops DFS (British retailer), a furniture retailer, ... DFS may refer to: Decoherence-free subspaces, subspace of a system's Hilbert space where the system is decoupled from the ...
*  IMP321
... when the median disease-free survival follow-up was 33 months. The results of this study were presented to the 25th Annual ... Stable disease. 7 of the 8 patients dosed at 6 mg had stable disease at 3 months compared with only 3 of 11 at lower dose. This ... arm relapsed during the first year whereas a majority of patients in the three other groups were still disease-free at follow- ... That paper demonstrated that soluble LAG3 correlated with improved survival in breast cancer patients whose tumors were ...
*  Ovarian cancer
... with a 5-year disease free survival rate of 93%, but stage II-IV tumors are less treatable, with survival rates of 64-91%. ... liver disease, inflammatory bowel disease, pelvic inflammatory disease, and leiomyoma. HE4 is another candidate for ovarian ... Ollier disease and Maffucci syndrome are associated with granulosa cell tumors in children and may also be associated with ... A blood test for a marker molecule called CA-125 is useful in differential diagnosis and in follow up of the disease, but it by ...
*  Cyproterone acetate
... added to castration has never been shown in any controlled study to prolong disease-free survival or ... This formulation is taken once daily for 21 days, followed by a 7-day free interval.[citation needed] CPA has also been ... Neil Kaplowitz (16 October 2002). Drug-Induced Liver Disease. CRC Press. pp. 618-. ISBN 978-0-203-90912-6. Kim JH, Yoo BW, Yang ... A variety of manifestations of liver disease in association with CPA treatment have been documented, including immunoallergic ...
*  Hodgkin's lymphoma
In this study, after two cycles of ABVD chemotherapy, 83% of patients were free of disease at 3 years if they had a negative ... Adding localised radiation therapy after the chemotherapy regimen may provide a longer progression-free survival compared with ... heart disease, or lung disease over the subsequent decades. In 2015 about 574,000 people had Hodgkin's lymphoma, and 23,900 ... announced in August 2015 that he was diagnosed with Hodgkin's disease. He later died of the disease in October 2015. Eric Berry ...
*  Parkin (ligase)
Parkin deficiency further diminished disease-free survival in infrared-irradiated mice without increasing tumour incidence rate ... French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease". ... The European Consortium on Genetic Susceptibility in Parkinson's Disease and the French Parkinson's Disease Genetics Study ... This form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease. In one study ...