Discovery and development of HIV-protease inhibitors
The observation that HIV-1 protease cleaves the sequences containing the dipeptides Tyr-Pro or Phe-Pro was the basic design ...
CORO6
It usually terminating at WD dipeptide at its C-terminus and is about 40 residues long, so called WD40. The structure of CORO6 ...
Angiotensin-converting enzyme
Likewise it converts the inactive decapeptide angiotensin I to the octapeptide angiotensin II by removing the dipeptide His-Leu ... ACE is also known by the following names: dipeptidyl carboxypeptidase I peptidase P dipeptide hydrolase peptidyl dipeptidase ... peptidyl dipeptidase-4 PDH peptidyl dipeptide hydrolase DCP CD143 ACE hydrolyzes peptides by the removal of a dipeptide from ... peptidyl dipeptidase I peptidyl-dipeptide hydrolase peptidyldipeptide hydrolase endothelial cell peptidyl dipeptidase ...
Carnosine
... (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is ... Acetylcarnosine, a similar molecule used to treat lens cataracts Anserine, another dipeptide antioxidant (found in birds) ...
Retosiban
... is a cyclic dipeptide or 2,5-diketopiperazine and these are formed by cyclising the corresponding linear dipeptide. ... Although the linear peptide 5 and the cyclic dipeptide 6 are a mixture of diastereoisomers (7RS) at the exocyclic amide, the ... enabled cyclization of the linear peptide 5 to occur to give the phenolic cyclic dipeptide 6. Hydrolysis of the phenolic amide ...
Epithelioid cell
"Three-dimensional study of epithelioid cells by a quick-freezing and deep-etching method in muramyl dipeptide-induced ...
Amitabha Mukhopadhyay
Srividya, S.; Roy, R. P.; Basu, S. K.; Mukhopadhyay, A. (2000). "Scavenger receptor-mediated delivery of muramyl dipeptide ...
WDR12
Each WD repeat typically contains a C-terminal tryptophan-aspartic acid dipeptide and an N-terminal glycine-histidine dipeptide ...
Potyvirus
HC-Pro (~52 KDa) is a cysteine protease which cleaves a glycine-glycine dipeptide at its own C-terminus. It also interacts with ...
Whey protein
Dipeptides, and Insulin Responses in Human Subjects". J. Agric. Food Chem. 58 (15): 8788-8797. "Protein Quality - Macros Inc - ...
Quisqualic acid
In addition, it also exhibits affinity for certain enzymes responsible for cleaving dipeptides, including the enzyme ...
Discovery and development of ACE inhibitors
They returned to work with carboxyl compounds and started working with substituted N-carboxymethyl-dipeptides as a general ... Synthesis and Evaluation of Four Diastereomers of Phe[Si]Ala Dipeptide Analogues", Journal of Organic Chemistry, 70 (15): 5781- ... But since ACE is a dipeptide carboxypeptidase, unlike carboxypeptidase A, the distance between the cationic carboxyl-binding ... However ACE releases dipeptides rather than single amino acids from the C-terminus of the peptide substrates. And it was ...
Pattern recognition receptor
NOD2 proteins recognize intracellular MDP (muramyl dipeptide), which is a peptidoglycan constituent of both Gram positive and ...
Foodomics
... a naturally occurring dipeptide and an intermediate in the gamma glutamyl cycle. Moreover, the result from an integration of ...
Alazopeptin
Kawai, Seiji; Katsuyama, Yohei; Ohnishi, Yasuo (2022-02-21). "The α/β Hydrolase AzpM Catalyzes Dipeptide Synthesis in ...
Photoactivated peptide
2007). "Investigation into the P3 binding domain of m-calpain using photoswitchable diazo- and triazene-dipeptide aldehydes: ...
Dihydrofolate reductase
The active site is situated in the N-terminal half of the sequence, which includes a conserved Pro-Trp dipeptide; the ...
Acetylcarnosine
... is a naturally occurring compound chemically related to the dipeptide carnosine. The NAC molecular structure is identical to ...
Oligopeptide
An oligopeptide, often just called peptide (oligo-, "a few"), consists of two to twenty amino acids and can include dipeptides ...
Digestion
Pepsin breaks down proteins into peptides or proteoses, which is further broken down into dipeptides and amino acids by enzymes ...
1901 in science
Emil Fischer, in collaboration with Ernest Fourneau, synthesizes the dipeptide, glycylglycine, and also publishes his work on ...
Isoglutamine
... can form the C-terminus of a peptide chain, as in muramyl dipeptide (MDP), a constituent of bacterial cell walls. ...
SdrG C terminal protein domain
SdrG stands for serine-aspartate dipeptide repeats, which as its name suggests, contains repeats of two amino acids, serine and ...
Gamma-glutamyltransferase 1
... catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. This ...
Neurotrophin mimetics
Among the peptidomimetic TrkB agonists, the dimeric dipeptide GSB-106 showed neurotrophic and neuroprotective effects by ... "Brain-derived neurotrophic factor loop 4 dipeptide mimetic GSB-106 activates TrkB, Erk, and Akt and promotes neuronal survival ...
Bacterial translation
The newly formed peptide in the A site tRNA is known as dipeptide and the whole assembly is called dipeptidyl-tRNA. The tRNA in ...
Glu-Glu dipeptidase
This enzyme catalyses the following chemical reaction Hydrolysis of the Glu!Glu dipeptide Pratt AG, Crawford EJ, Friedkin M ( ...
Dipeptidyl-peptidase I
This enzyme catalyses the following chemical reaction Release of an N-terminal dipeptide, Xaa-Yaa!Zaa-, except when Xaa is Arg ... Dipeptidyl peptidase I (EC 3.4.14.1, cathepsin C, dipeptidyl aminopeptidase I, dipeptidyl transferase, dipeptide arylamidase I ...
Metalloexopeptidase
Analogous to slicing the end off a loaf of bread, the process releases a single amino acid (or dipeptide) for use. The terms " ...
Roman Dziarski
Dziarski, R. (Jan 1988). "Enhancement of B-cell stimulation by muramyl dipeptide through a mechanism not involving interleukin ... muramyl dipeptide- and lipopolysaccharide-induced mitogenic stimulation in B lymphocytes". European Journal of Immunology. 19 ( ...