*Phenelzine

... is used primarily in the treatment of major depressive disorder (MDD). Patients with depressive symptomology ... In addition to being a recognized treatment for major depressive disorder, phenelzine is effective in treating dysthymia, ... bipolar depression (BD), panic disorder (PD), social anxiety disorder, bulimia, and post-traumatic stress disorder (PTSD). ... GABA is the major inhibitory neurotransmitter in the mammalian central nervous system, and is very important for the normal ...

*Major depressive disorder

At least one of these must be present to make a diagnosis of major depressive episode. Major depressive disorder is classified ... Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of ... Other disorders need to be ruled out before diagnosing major depressive disorder. They include depressions due to physical ... Bipolar disorder, also known as manic-depressive disorder, is a condition in which depressive phases alternate with periods of ...

*Melatonin treatments for major depressive disorder

Major depressive disorders are frequently associated with circadian dis-regulations which have been known to bring on ... "Melatonin for the treatment of sleep disturbances in major depressive disorder". The American Journal of Psychiatry. 155 (8): ... studies have heavily suggested that the use of melatonin has been successful in treating symptoms of major depressive disorders ... Depressive symptoms were measured using the Hamilton Rating Scale for Depression (HRSD) both pre and post treatment. Overall ...

*Depressive Disorder Not Otherwise Specified

DD-NOS is diagnosed if a patients symptoms fail to meet the criteria more common depressive disorders such as major depressive ... Depressive Disorder Not Otherwise Specified (DD-NOS) is designated by the code 311 in the DSM-IV for depressive disorders that ... A diagnosis of the disorder will look like: "Depressive Disorder NOS 311". Accurately assessing for a specific Depressive ... Missing or empty ,url= (help) "Clinical Practice Guideline for Management of Major Depressive Disorder" (PDF). DHCC Clinicians ...

*Fluparoxan

Belmaker RH, Agam G (January 2008). "Major depressive disorder". New England Journal of Medicine. 358 (1): 55-68. doi:10.1056/ ... Cottingham C, Wang Q (November 2012). "α2 Adrenergic receptor dysregulation in depressive disorders: implications for the ... This release of noradrenaline has a potential value in the treatment of disorders which are associated with a deficiency of ... adrenoceptors to increase brain levels of noradrenalin is insufficient as a neurobiological basis for depressive disorders, ...

*CREB

There is some evidence to suggest that the under-functioning of CREB is associated with Major Depressive Disorder. Depressed ... From post-mortem examinations it has also been shown that the cortices of patients with untreated major depressive disorder ... Dysfunction of these neurotransmitters is also implicated in major depressive disorder. CREB is also thought to be involved in ... Belmaker, R. H.; Agam, Galila (2008). "Major depressive disorder". New England Journal of Medicine. 358 (1): 55-68. doi:10.1056 ...

*Marmite

Hall-Flavin, Daniel K. (19 January 2016). "Depression (major depressive disorder)". Mayo Clinic. Retrieved 1 September 2016. ... The first major Marmite advertising campaign began in the 1930s, with characters whose faces incorporated the word 'good'. Soon ...

*Emanuel Leplin

His diagnosis was major depressive disorder. Dora Leplin, a seamstress, raised Leplin, then called "Manny", by herself. Daniel ... "Leplin's Major Addition To Music of Synagogue," S.F. Examiner, February 23, 1965, p. 34 Schneider, 1983 Program of the Little ...

*Vagal tone

Rottenberg, Jonathan; Clift, April; Bolden, Sarah; Saloman, Kristen (2007). "RSA fluctuation in major depressive disorder". ... and internalizing and externalizing disorders). Research indicates that children with more secure attachments with their ...

*Depression (mood)

When the course of depressive episodes follows a seasonal pattern, the disorder (major depressive disorder, bipolar disorder, ... The mood disorders are a group of disorders considered to be primary disturbances of mood. These include major depressive ... the symptoms of which do not meet the severity of a major depressive episode. Another mood disorder, bipolar disorder, features ... Cipriani, Andrew (8 June 2016). "Comparative efficacy and tolerability of antidepressants for major depressive disorder in ...

*Biology of depression

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium; Ripke, S; Wray, N. R.; Lewis, C. M.; Hamilton, S. P ... In major depressive disorder, anxiety is often a part of the emotional state that characterizes depression. Biological ... The amygdala, a structure involved in emotional processing appears to be hyperactive in those with major depressive disorder. ... Hamilton, J. Paul; Siemer, Matthias; Gotlib, Ian H. (8 Sep 2009). "Amygdala volume in Major Depressive Disorder: A meta- ...

*MDD2

Major depressive disorder 2 is a protein that in humans is encoded by the MDD2 gene. "Human PubMed Reference:". "Entrez Gene: ... Major depressive disorder 2". Retrieved 2017-09-15. ...

*Cancer survivor

About 10% develop major depressive disorder; others experience an adjustment disorder. In young adult cancer survivors, one ... Twombly R (February 2001). "Post-traumatic stress disorder in childhood cancer survivors: how common is it?". J. Natl. Cancer ... This is especially important for the AYA population, in particular, because they are typically facing major social changes ... Issues of pain and physical ailments have been hypothesized as major contributing factors in cancer survivors experiencing this ...

*Glucocorticoid receptor

Free full text] Savitz J, Lucki I, Drevets WC (2009). "5HT1A receptor function in Major Depressive Disorder". Prog Neurobiol. ... functioning as a major component of endocrine influence - specifically the stress response - upon the brain. The receptor is ... including some or all subtypes of depression and post-traumatic stress disorder (PTSD). Indeed, long-standing observations such ... and long-term adaptations seen in response to stressors and may be critical to the understanding of psychological disorders, ...

*Hippocampus

"Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder". Archives of ... impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients". The ... A major output goes via the fornix to the lateral septal area and to the mammillary body of the hypothalamus (which the fornix ... The second major line of thought relates the hippocampus to memory. Although it had historical precursors, this idea derived ...

*Antidepressant

They are also frequently used as antidepressants for the treatment of major depressive disorder, anxiety and panic disorder. ... Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, ... "Practice Guideline for the Treatment of Patients With Major Depressive Disorder". PsychiatryOnline (Third Edition ed.). CS1 ... "Amitriptyline versus placebo for major depressive disorder". Cochrane Database of Systematic Reviews. 12: CD009138. doi:10.1002 ...

*Buprenorphine/samidorphan

Business Wire (2013). "Alkermes Receives Fast Track Designation for ALKS 5461 for Major Depressive Disorder". Buprenorphine/ ... "Investigational drugs for treating major depressive disorder". Expert opinion on investigational drugs. 26 (1): 9-24. doi: ... "Evaluation of Opioid Modulation in Major Depressive Disorder". Neuropsychopharmacology. 40: 1448-55. doi:10.1038/npp.2014.330. ... the changes in neuroplasticity evoked by chronic stress that lead to the development of depressive and anxiety disorders, ...

*Richard Kogan (physician)

He clearly had a major depressive disorder; Schumann was clearly bipolar. Beethoven was interesting; I have had trouble getting ... as a child would probably today have been diagnosed with conduct disorder and with attention-deficit hyperactivity disorder. ... He was a hyperactive kid who showed signs of conduct disorder." But at age 10 or 11 Gershwin, while playing hooky from school ... At Harvard University, where he studied music (his major) and completed a pre-medical curriculum, Kogan formed a trio with his ...

*Depression in childhood and adolescence

Some young people, especially those with co-morbid conduct disorder and major depressive disorder, may have had undiagnosed and ... such as the mood disorders major depressive disorder and dysthymia. Depression in childhood and adolescence is similar to adult ... Although antidepressants were used by child and adolescent psychiatrists to treat major depressive disorder, they may not ... Childhood depression is often co-morbid with mental disorders outside of other mood disorders; most commonly anxiety disorder ...

*Cerebellar cognitive affective syndrome

Cerebellar vermis volume in major depressive disorder. Brain Structucture & Function, [Epub ahead of print] Andreasen, N. C., ... bipolar disorder, attention deficit hyperactivity disorder (ADHD), developmental dyslexia, Down syndrome, and Fragile X ... There are a number of psychiatric disorders that are thought to be related to dysfunction of the cerebellum and that appear ... There are several pieces of evidence that support the hypothesis that symptoms of some psychiatric disorders are the result of ...

*List of investigational antidepressants

All drugs listed are specifically under development for major depressive disorder (MDD) or treatment-resistant depression (TRD ... Dhir A (2017). "Investigational drugs for treating major depressive disorder". Expert Opin Investig Drugs. 26 (1): 9-24. doi: ... specifically under development for the treatment of MDD and depressive episodes in bipolar disorder Ademetionine (SAMe; MSI-190 ... specifically under development for the treatment of depressive episodes in bipolar disorder Lurasidone (Latuda) - AA - ...

*Behavioral theories of depression

Clinical psychology Major depressive disorder Haddad, Mark; Gunn, Jane (August 2011). Fast Facts: Depression (3rd ed.). ... This variability has been linked to a decrease in depressive symptoms and to a typical behavioral profile. The ultimate goal is ... It argues that people with depression act in ways that maintain their depression and locates the origin of depressive episodes ... Clark, Lee; Watson, David; Mineka, Susan (1994). "Temperament, personality, and the mood and anxiety disorders". Journal of ...

*Occupational health psychology

Occupations and the prevalence of major depressive disorder. Journal of Occupational Medicine, 32(11), 1079-1087. Wang J. (2005 ... Work stress as a risk factor for major depressive episode(s). Psychological Medicine, 35, 865-871. doi:10.1017/ ... such as substance abuse and co-morbid mental disorders, can plague sufferers. However, personality disorders can also bring ... Musculoskeletal disorders (MSDs) involve injury and pain to the joints and muscles of the body. Approximately 2.5 million ...

*Essential fatty acid interactions

KP Su; SY Huang; CC Chiu; WW Shen (2003). "Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, ... See discussion of PGE2 at Calder or Tilley.) Figure (2) shows the ω-3 and -6 synthesis chains, along with the major eicosanoids ... Eicosanoids are signalling molecules derived from the essential fatty acids (EFA); they are a major pathway by which the EFAs ... There is also more preliminary evidence showing that dietary ω-3 can ease symptoms in several psychiatric disorders. ...

*Fish oil

Su, Kuan-Pin; Huang, Shih-Yi; Chiu, Chih-Chiang; Shen, Winston W. (2003). "Omega-3 fatty acids in major depressive disorder". ... meta-analysis of eleven trials conducted respectively on patients with a DSM-defined diagnosis of major depressive disorder ( ... "Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical ... "Addition of Omega-3 Fatty Acid to Maintenance Medication Treatment for Recurrent Unipolar Depressive Disorder". American ...

*Brain ischemia

Baldwin, Robert C. (2005). "Is vascular depression a distinct sub-type of depressive disorder? A review of causal evidence". ... heart attacks may slow blood flow enough that blood may start to clot and prevent the flow of blood to the brain or other major ... Encyclopedia of Neurological Disorders: Hypoxia[permanent dead link]. health.enotes.com. URL last accessed February 26, 2006. ( ... "Cerebral Hypoxia Information Page". National Institute of Neurological Disorders and Stroke. National Institutes of Health. ...

*Liothyronine

Levothyroxine Major depressive disorder Hypothyroidism Rosenthal, Lisa J.; Goldner, Whitney S.; O'Reardon, John P. (October ... It is also used as an augmentation strategy in treating major depressive disorder when used in combination with antidepressants ... "T3 augmentation in major depressive disorder: safety considerations". Am. J. Psychiatry. 168 (10): 1035-1040. doi:10.1176/appi. ... "Thyroid hormones association with depression severity and clinical outcome in patients with major depressive disorder". ...