Loading...
*  Lymph node stromal cell
... dendritic cells move to the T cell zone or to the B cell follicle along the fibroblast reticular cell network. Dendritic cells ... The sub-populations include: fibroblastic reticular cells (FRCs); folicular dendritic cells (FDCs); lymphatic endothelial cells ... Lymph node stromal cells can give rise to a number of malignancies including: follicular dendritic cell sarcoma; fibroblastic ... Antigens are also presented on the surface of dendritic cells. In an inflammatory state, lymphatic endothelial cells increase ...
*  Antigen-presenting cell
Only licensed dendritic cells are able to activate cytotoxic T cells. T cell licensing of dendritic cells is key for activation ... The main types of professional antigen-presenting cells are dendritic cells, macrophages and B cells. Dendritic cells have the ... These immature dendritic cells are ineffective at presenting antigen to T helper cells. Once a dendritic cell's pattern- ... B cells can internalize antigen that binds to their B cell receptor and present it to helper T cells. Unlike T cells, B cells ...
*  Mixed lymphocyte reaction
Further characterization of the lymphocytes, accessory cells (dendritic cells, macrophage) and cytokines that participate in ... MLR's are performed to assess how T-cells react to external stimuli. T cells are a type of white blood cell that scans for ... lymph nodes or spleen and co-culturing with stimulator cells. Stimulator cell populations that also contain T-cells (Two way ... differences between the two cell populations designated as Responder and Stimulator cells. Responder cells proliferated without ...
*  Follicular dendritic cells
... (FDCs) are cells of the immune system found in primary and secondary lymph follicles of the B cell ... These cells were first described in 1965 and, although they have a very dendritic morphology, are not dendritic cells (DCs). ... and the skin of patients with pseudo B cells lymphoma. Follicular dendritic cells participate in HIV-1 infection development ... and differentiation into high-affinity plasma cells and memory B cells. Adhesion between FDCs and B cells is mediated by ICAM-1 ...
*  Dendritic cell
Dendritic cells have also been found in chickens and turtles. A dendritic cell Play media A well-resolved dendritic cell drags ... concurrent interaction of all three cell types, namely CD4+ T helper cells, CD8+ T cells and dendritic cells, seems to be ... The morphology of dendritic cells results in a very large surface-to-volume ratio. That is, the dendritic cell has a very large ... Whereas mature dendritic cells are able to activate antigen-specific naive CD8+ T cells, the formation of CD8+ memory T cells ...
*  Plasmacytoid dendritic cell
Plasmacytoid dendritic cells (pDCs) are innate immune cells that circulate in the blood and are found in peripheral lymphoid ... In humans they exhibit plasma cell morphology and express CD4, HLA-DR, CD123, blood-derived dendritic cell antigen-2 (BDCA-2), ... Tversky JR, Le TV, Bieneman AP, Chichester KL, Hamilton RG, Schroeder JT (May 2008). "Human blood dendritic cells from allergic ... June 2010). "Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells". ...
*  Dendritic cells- based cancer vaccines
Dendritic cells (DCs) are most powerful antigen presenting cells for the induction of antigen specific T cell response and ... "The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed ... Plasmacytoid dendritic cells (pDCs) differentiate from lymphoid progenitor cells in the lymphoid tissues. They express CD123 ... "Dendritic cells: Immunological sentinels with a central role in health and disease". Immunology and Cell Biology. 78 (2): 91- ...
*  Follicular dendritic cell sarcoma
Cyclophosphamide slows or stops cell growth cells. It targets cells that are rapidly dividing which include cancer cells that ... Tew, John G.; Kosco, Marie H.; Burton, Gregory F.; Szakal, Andras K. (1990). "Follicular Dendritic Cells as Accessory Cells". ... Fonseca, Rafael; Tefferi, Ayalew; Strickler, John G. (1997). "Follicular dendritic cell sarcoma mimicking diffuse large cell ... "Follicular dendritic cell sarcoma and interdigitating reticulum cell sarcoma: A review". American Journal of Hematology. 59 (2 ...
*  Interdigitating dendritic cell sarcoma
... is a form of malignant histiocytosis affecting dendritic cells. It can present in the ... Kawachi K, Nakatani Y, Inayama Y, Kawano N, Toda N, Misugi K (April 2002). "Interdigitating dendritic cell sarcoma of the ... Kanaan H, Al-Maghrabi J, Linjawi A, Al-Abbassi A, Dandan A, Haider AR (February 2006). "Interdigitating dendritic cell sarcoma ...
*  Acute myeloid dendritic cell leukemia
In the case of acute myeloid dendritic cell leukemia, the blast cells are positive for markers of dendritic cells or monocytes ... the myeloid dendritic cell and the plasmacytoid dendritic cell. Leukemic transformation can occur in any of these two cells, ... Dendritic cells function as antigen-presenting cells. They process antigen material and present it on the surface to other ... The neoplastic dendritic cells are negative for the enzymes myeloperoxidase and esterase. The cells elaborate many cytokines ...
*  4-1BB ligand
4-1BBL (4-1BB ligand) is found on APCs (antigen presenting cells) and binds to 4-1BB. CD137L Lotze, Michael (2001). Dendritic ... Cells. Boston: Academic Press. ISBN 0-12-455851-8. 4-1BB Ligand at the US National Library of Medicine Medical Subject Headings ...
*  Formyl peptide receptor 3
Yang D, Chen Q, Gertz B, He R, Phulsuksombati M, Ye RD, Oppenheim JJ (Sep 2002). "Human dendritic cells express functional ... tissue macrophages and dendritic cells. The functions of FPR3 and the few ligands which activate it have not been fully ... "The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide ... 1 by cathepsin D cleavage that potently stimulates chemotaxis through FPR3 in monocytes and monocyte-derived dendritic cells. ...
*  FMS-like tyrosine kinase 3 ligand
FLT3L is crucial for steady-state plasmacytoid dendritic cell (pDC) and classical dendritic cell (cDC) development. A lack of ... In strains of plasmodium, FLT3L was shown to be released from mast cells and cause the expansion of dendritic cells, leading to ... Guermonprez, Pierre; Helft, Julie (2013). "Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses ... Rahman, Adeeb H.; Aloman, Costica (2013). "Dendritic cells and liver fibrosis". Biochimica et Biophysica Acta. 1832 (7): 998- ...
*  Foam cell
The link between atherosclerosis and autoimmunity is plasmacytoid dendritic cells (pDCs). PDCs contribute to the early stages ... Foam cells form the fatty streaks of the plaques of atheroma in the tunica intima of arteries. Foam cells are not dangerous as ... doi: 10.1007/s10616-010-9290-0 Dӧring, Y., Zernecke, Z. (2012). "Plasmacytoid Dendritic Cells in Atherosclerosis". Frontiers in ... Foam cells are formed when circulating monocyte-derived cells are recruited to the atherosclerotic lesion site or fat deposits ...
*  Kayo Inaba
"Dendritic Cell Development and Maturation". In Paola Ricciardi-Castagnoli. Dendritic Cells in Fundamental and Clinical ... "Expression of B7 Costimulator Molecules on Mouse Dendritic Cells". In Jacques Banchereau; Daniel Schmitt. Dendritic Cells in ... Inaho is known for her work on dendritic cells and she won the Asia pacific UNESCO Awards for Women in Science in 2014. She has ... Contributions of Dendritic Cells". In Ralph M. Steinman; Robert John North. Mechanisms of Host Resistance to Infectious Agents ...
*  Immune checkpoint
Its ligand is ICOSL, expressed mainly on B cells and dendritic cells. The molecule seems to be important in T cell effector ... Binding with its two ligands are CD80 and CD86, expressed on dendritic cells, prompts T cell expansion. CD28 was the target of ... CD40 signaling is known to 'license' dendritic cells to mature and thereby trigger T-cell activation and differentiation. A now ... CD137-mediated signaling is also known to protect T cells, and in particular, CD8+ T cells from activation-induced cell death. ...
*  Antigen
Gallucci, S; Lolkema, M; Matzinger, P (November 1999). "Natural adjuvants: endogenous activators of dendritic cells". Nature ... In order to keep the cytotoxic cells from killing cells just for presenting self-proteins, the cytotoxic cells (self-reactive T ... T cells cannot bind native antigens, but require that they be processed by APCs, whereas B cells can be activated by native ... For T-Cell Receptor (TCR) recognition, the peptide must be processed into small fragments inside the cell and presented by a ...
*  Nasal-associated lymphoid tissue
Dendritic cells and macrophages are also present. NALT contains about same amount of T cells and B cells. The T-cell population ... T cell and B cell enriched zones, follicle-associated epithelium (FAE) with epithelial M cells and some erythrocytes. M cells ... Most of T cells are with αβ T cell receptor (TCR) and only few are with γδ TCR. CD4+ T cells are in naive state, marked by high ... It requires Id2 gene, witch induce genesis of CD3−CD4+CD45+ cells. These cells accumulates on the site of NALT after birth and ...
*  CpG Oligodeoxynucleotide
... and induced the maturation of plasmacytoid dendritic cells. Class A ODN are also strong activators of NK cells through indirect ... which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs) in humans and other higher primates. ... Rothenfusser, S; Tuma, E; Endres, S; Hartmann, G (2002). "Plasmacytoid dendritic cells: the key to CpG". Human immunology. 63 ( ... "Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells". ...
*  Artificial immune system
Dendritic Cell Algorithms: The Dendritic Cell Algorithm (DCA) is an example of an immune inspired algorithm developed using a ... This algorithm is based on an abstract model of dendritic cells (DCs). The DCA is abstracted and implemented through a process ... Greensmith, J.; Aickelin, U. (2009). "Artificial Dendritic Cells: Multi-faceted Perspectives" (PDF). Human-Centric Information ... Negative selection refers to the identification and deletion (apoptosis) of self-reacting cells, that is T cells that may ...
*  Cluster of differentiation
... dendritic cells express high levels of CD8). Human immunodeficiency virus (HIV) binds CD4 and a chemokine receptor on the ... This CD combination typically corresponds to a stem cell, as opposed to a fully differentiated endothelial cell. Some cell ... see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD ... Ho IC, Tai TS, Pai SY (February 2009). "GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell ...
*  CD14
... + monocytes can differentiate into a host of different cells, including dendritic cells, a differentiation pathway ... It is also expressed by dendritic cells. The soluble form of the receptor (sCD14) is secreted by the liver and monocytes and is ... "CD14 Is Expressed and Released as Soluble CD14 by Human Intestinal Epithelial Cells In Vitro: Lipopolysaccharide Activation of ... myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones". Biochimica et Biophysica Acta. ...
*  Systemic inflammation
Chief among these are dendritic cells (DCs). When a DC presents an antigen to a Treg cell, a signal is then sent to the nucleus ... research suggests that a lack of control by tolerogenic dendritic cells and T-regulatory cells (Treg) is possibly the primary ... T-helper and T-cytotoxic cells are activated by presentation of antigens by antigen-presenting cells (APCs). ... Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the ...
*  Vaccine
Dendritic cell vaccines combine dendritic cells with antigens in order to present the antigens to the body's white blood cells ... Kim W, Liau LM (2010). "Dendritic cell vaccines for brain tumors". Neurosurg Clin N Am. 21 (1): 139-57. doi:10.1016/j.nec. ... Anguille, S; Smits, EL; Lion, E; van Tendeloo, VF; Berneman, ZN (June 2014). "Clinical use of dendritic cells for cancer ... Some cells of the immune system that recognize the proteins expressed will mount an attack against these proteins and cells ...
*  Linker histone H1 variants
... histone and differentiation of dendritic cells. A molecular target for tumor-derived factors". Journal of Leukocyte Biology. 72 ... Cell. 123 (7): 1199-1212. doi:10.1016/j.cell.2005.10.028. ISSN 0092-8674. PMID 16377562. Gabrilovich, Dmitry I.; Cheng, Pingyan ... "The genomic landscape of the somatic linker histone subtypes H1.1 to H1.5 in human cells". Cell Reports. 3 (6): 2142-2154. doi: ... In human and mouse cells 11 H1 variants have been described and are encoded by single genes. Six of the variants are mainly ...
*  LILRA3
... and dendritic cells involved in antigen processing". The Journal of Experimental Medicine. 185 (10): 1743-51. doi:10.1084/jem. ... an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions ... "A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells ... "Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for ...
*  Venous translucence
Cherian, SM; Bobryshev, YV; Inder, SJ; Lord, RS; Ashwell, KW (1999) Dendritic Cells in Venous Pathologies. 50: 393-402 Cronan, ... AM (1998) Fluid Shear Stress Stimulates Phosphorylation of Akt in Human Endothelial Cells: Involvement in Suppression of ...