The von Magnus phenomenon describes the generation of defective interfering particles (DIPs) by viruses. It was first observed ... Gard, S. (1952). "Studies on the sedimentation of influenza virus". Archiv für die Gesamte Virusforschung. 4 (5): 591-611. doi: ... Kristen Ann Stauffer Thompson (2008). Quantitative Effects of Defective Interfering Virus-like Particles on the Growth and ... by Preben von Magnus in influenza viruses, after the serial passage of undiluted allantoic fluid in eggs. ...

Despite the inability to isolate them, von Magnus discovered defective interfering particles (DIPs) using the "influenza virus ... Huang, Alice S.; Baltimore, David (1977). "2. Defective Interfering Animal Viruses". In Fraenkel-Conrat, Heinz; Wagner, Robert ... "Incomplete Forms of Influenza Virus", in Kenneth M. Smith and Max A. Lauffer's Advances in Virus Research, Volume 2, Academic ... "incomplete viruses" or "particles" were produced and that these interfered with viral replication. This resulted in a reduction ...

2012-12-12). "Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows ... Marriott AC, Dimmock NJ (January 2010). "Defective interfering viruses and their potential as antiviral agents". Reviews in ... "Defective interfering influenza virus confers only short-lived protection against influenza virus disease: evidence for a role ... July 2021). "Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro ...

Defective interfering particles (DIPs), also known as defective interfering viruses, are spontaneously generated virus mutants ... 2012). "Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows ... In other words, defective and non-defective viruses replicate simultaneously, but when defective particles increase, the amount ... deficient rabies virus defective interfering particle RNA is replicated and transcribed by heterologous helper virus L proteins ...

Mammalian influenza viruses tend to be labile, but can survive several hours in mucus. Avian influenza virus can survive for ... Each virion may contain defective interfering copies. In Influenza A (H1N1) PB1-F2 is produced from an alternative reading ... In general, the virus's morphology is ellipsoidal with particles 100-120 nm in diameter, or filamentous with particles 80-100 ... After the release of new influenza virus, the host cell dies. Orthomyxoviridae viruses are one of two RNA viruses that ...

Defective interfering particles (RNA) Defective interfering particles (DNA) Viruses portal Glossary of scientific naming ... Ebola and Marburg viruses are well known members of this group, along with influenza virus, measles, mumps and rabies. All ... and foot-and-mouth virus), SARS virus, hepatitis C virus, yellow fever virus, and rubella virus. Group V: viruses possess ... interfering particles are defective viruses that have lost their ability to replicate except in the presence of a helper virus ...

In this variation, serum antibodies to the influenza virus will interfere with the virus attachment to red blood cells. ... PCR amplifies all target nucleic acid, including ones originating from intact infectious viral particles, from defective viral ... It relies on the fact that hemagglutinin, a surface protein of influenza viruses, agglutinates red blood cells (i.e. causes red ... Virus quantification is counting or calculating the number of virus particles (virions) in a sample to determine the virus ...

... but was subsequently also found with pathogenic viruses including influenza virus, HIV-1, adenovirus simian virus 40, vaccinia ... The envelope covering the virus particle then fuses with the cell membrane, creating a pore through which the contents of the ... "Zinc ionophores pyrithione inhibits herpes simplex virus replication through interfering with proteasome function and NF-κB ... MR of HSV appears to partially depend on the host cell recombinational repair machinery since skin fibroblast cells defective ...

... of vesicular stomatitis virus are conditionally defective particles that interfere with and are rescued by wild-type virus". ... Cold-adapted equine influenza viruses, retrieved 2016-01-26 Youngner, Julius S.; Dowling, Patricia W. (Sep 22, 1992), Method of ... Youngner is responsible for the first equine influenza vaccine, based upon cold-adapted influenza virus. Previous methods of ... "one live virus particle in 100 million doses of vaccine." By 1954, the first virus trials had immunized 800,000 children ...

... 1's A to I editing has been found in many viruses including measles virus, influenza virus, lymphocytic choriomeningitis ... "Biased hypermutation and other genetic changes in defective measles viruses in human brain infections". Cell. 55 (2): 255-265. ... ADAR impacts the transcriptome in editing-independent ways, likely by interfering with other RNA-binding proteins. Mutations in ... "Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles". Journal of ...

Some viruses, and in particular paramyxoviruses, can produce new virus particles by fusing infected and healthy host cells. ... Defective interfering (DI) genomes or defective viral genomes (DVGs) are replication defective viral RNA products generated ... Killian ML (2008). "Hemagglutination Assay for the Avian Influenza Virus". Avian Influenza Virus. Methods in Molecular Biology ... human immunodeficiency virus, influenza virus A and Sendai virus". Advances in Enzyme Regulation. 36: 325-47. doi:10.1016/0065- ...

When this happens with influenza viruses, pandemics might result. RNA viruses often exist as quasispecies or swarms of viruses ... Plant virus particles or virus-like particles (VLPs) have applications in both biotechnology and nanotechnology. The capsids of ... It is, therefore, a defective virus. Although hepatitis delta virus genome may replicate independently once inside a host cell ... and antiviral drugs that selectively interfere with viral replication. Vaccination is a cheap and effective way of preventing ...

Cellular infection by viruses such as HIV and influenza also involve folding events on cell membranes. Once protein misfolding ... In 2009, researchers used Folding@home to study mutations of influenza hemagglutinin, a protein that attaches a virus to its ... The catalytic activity depends on the size of the particle. PrPSc particles which consist of only 14-28 PrPc molecules exhibit ... Ideally, a drug should act very specifically, and bind only to its target without interfering with other biological functions. ...

... a helper virus. Adenovirus and the herpes viruses act as helper viruses for AAV. AAV persists within the cell outside of the ... The defective gene of the patient's blood cells was replaced by the functional variant. Ashanti's immune system was partially ... Short pieces of double-stranded RNA (short, interfering RNAs or siRNAs) are used by cells to degrade RNA of a particular ... In academic contexts, a number of laboratories are working on delivery of PEGylated particles, which form serum protein coronas ...

A founder virus can introduce a different phenotype for the ensuing evolution. Evolution of viruses in nature and as disease ... Aaskov J, Buzacott K, Thu HM, Lowry K, Holmes EC (January 2006). "Long-term transmission of defective RNA viruses in humans and ... first by clonal analyses of RNA bacteriophage Qβ populations whose replication had been initiated by a single virus particle. ... González-López C, Arias A, Pariente N, Gómez-Mariano G, Domingo E (April 2004). "Preextinction viral RNA can interfere with ...

Although phagocytes and other components of the innate immune system can, to a limited extent, control viruses, once a virus is ... Third, some species of bacteria can inhibit the ability of phagocytes to travel to the site of infection by interfering with ... Non-professional phagocytes are more limited than professional phagocytes in the type of particles they can take up. This is ... Charley B, Riffault S, Van Reeth K (October 2006). "Porcine innate and adaptative immune responses to influenza and coronavirus ...