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*  Tumor-associated macrophage
Type II cytokines, which are secreted by them, can promote anti-inflammatory reaction and thus promote tumor growth. However, ... TAMs interact with a wide range of growth factors, cytokines and chemokines in the tumor microenvironment which is thought to ... M2 tumor-associated macrophages secrete many proteases such as cathepsin, cytokines, and an epidermal growth factor. The ... The TME consists of hypoxic conditions, growth factors and immunosuppressive cytokines that convert trophic macrophages to ...
*  Cytokine
... Signalling Forum Cytokine Tutorial Cytokine Gene Summary, Ontology, Pathways and More: Immunology Database and ... likely increasing cytokine levels. Another important example of cytokine storm is seen in acute pancreatitis. Cytokines are ... Over-secretion of cytokines can trigger a dangerous syndrome known as a cytokine storm; this may have been the cause of severe ... Some cytokines enhance or inhibit the action of other cytokines in complex ways. They are different from hormones, which are ...
*  Cytokine (journal)
Cytokine is a monthly peer-reviewed academic journal covering the study of cytokines as they relate to multiple disciplines, ... It is the official journal of the International Cytokine & Interferon Society. The editor-in-chief is Dhan Kalvakolanu ( ... "Cytokine". 2016 Journal Citation Reports. Web of Science (Science ed.). Clarivate Analytics. 2017. Official website. ...
*  Proinflammatory cytokine
A proinflammatory cytokine or more simply an inflammatory cytokine is a type of signaling molecule (a cytokine) that is ... A proinflammatory cytokine or an inflammatory cytokine is a type of cytokine (signaling molecule) that is excreted from immune ... The kidney proximal tubule cells produce proinflammatory cytokines in response to lipopolysaccaride. Proinflammatory cytokines ... Some inflammatory cytokines have additional roles such as acting as growth factors. Pro-inflammatory cytokines such as IL-1β, ...
*  Cytokine receptor
... s are receptors that bind cytokines. In recent years, the cytokine receptors have come to demand the attention ... Soluble cytokine receptors are extremely common regulators of cytokine function. Soluble cytokine receptors typically consist ... Cytokine receptors at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and cellular biology portal ... A classification of cytokine receptors based on their three-dimensional structure has been attempted. (Such a classification, ...
*  Cytokine storm
... s have potential to do significant damage to body tissues and organs. If a cytokine storm occurs in the lungs, ... A cytokine storm, also known as cytokine cascade and hypercytokinemia, is a potentially fatal immune reaction consisting of a ... In addition, cytokines activate those cells, stimulating them to produce more cytokines. Normally, the body keeps this feedback ... Human deaths from the bird flu H5N1 usually involve cytokine storms as well. Cytokine storm has also been implicated in ...
*  Cytokine redundancy
... is associated with the term cytokine pleiotropy, which refers to the ability of cytokines to exert multiple ... "Cytokine and Cytokine Receptor Pleiotropy and Redundancy", JBC, 277:29355-8. Nicola, N. A. (1994.) "Cytokine pleiotropy and ... Cytokine redundancy is a term in immunology referring to the phenomenon in which, and the ability of, multiple cytokines to ... Kelso, A. (1993.) "The enigma of cytokine redundancy", Immunology and Cell Biology, 72:97-101. LaPorte, S. L.; Juo, Z. S.; ...
*  Cytokine release syndrome
"In vitro cytokine release assays for predicting cytokine release syndrome: the current state-of-the-science. Report of a ... Cytokine release syndrome is an adverse effect of some monoclonal antibody drugs, as well as adoptive T-cell therapies. Severe ... and monocytes are activated and release inflammatory cytokines, which in turn activate yet more white blood cells. CRS has ... "Current concepts in the diagnosis and management of cytokine release syndrome". Blood. 124 (2): 188-95. doi:10.1182/blood-2014- ...
*  Cytokine adsorbing column
Cytokine-adsorbing columns remove inflammatory mediators from the body. They are being studied in sepsis. Specific products ...
*  Cytokine-induced killer cell
They were given the name "cytokine-induced killer" because cultivation with certain cytokines is mandatory for the maturation ... Cytokine-induced killer cells or CIK cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) ... Cytokine-Induced Killer Cells at the US National Library of Medicine Medical Subject Headings (MeSH) International registry on ... These cytokines strongly stimulate the proliferation and maturation into CIK cells. After completed maturation CIK cells are ...
*  Type I cytokine receptor
... s are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines ... Members of the type I cytokine receptor family comprise different chains, some of which are involved in ligand/cytokine ... Type I cytokine receptors include interleukin receptors, colony stimulating factor receptors and other cytokine receptors ... Cytokine Receptors at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Type II cytokine receptor
... which bind and respond to a select group of cytokines. These receptors are similar to type I cytokine receptors except they do ... Type II cytokine receptors include those that bind type I and type II interferons, and those that bind members of the ... Typically type II cytokine receptors are heterodimers or multimers with a high and a low affinity component. Currently no ... Type II cytokine receptors are transmembrane proteins that are expressed on the surface of certain cells, ...
*  Suppressor of cytokine signalling
SOCS (suppressor of cytokine signaling proteins) refers to a family of genes involved in inhibiting the JAK-STAT signaling ... CISH SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SOCS7 Suppressor of Cytokine Signaling Proteins at the US National Library of Medicine ...
*  Cytokine dependent hematopoietic cell linker
... is a protein that in humans is encoded by the CLNK gene. MIST is a member of the ... Cytokine dependent hematopoietic cell linker". Retrieved 2017-09-06. Cronin S, Tomik B, Bradley DG, Slowik A, Hardiman O (2009 ...
*  Suppressor of cytokine signaling 1
SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced ... Suppressor of cytokine signaling 1 is a protein that in humans is encoded by the SOCS1 gene. SOCS1 orthologs have been ... Suppressor of cytokine signaling 1 has been shown to interact with: CD117, Colony stimulating factor 1 receptor Growth hormone ... Wang J, Campbell IL (2002). "Cytokine signaling in the brain: putting a SOCS in it?". J. Neurosci. Res. 67 (4): 423-7. doi: ...
*  Bryan Williams (professor)
"Committees". Cytokines-interferons. Retrieved 17 October 2016. Parallelus (24 May 1990). "Bryan R.G. Williams, Ph.D. - The ... "Newsletter" (PDF). Cytokines-interferons.org. Retrieved 17 October 2016. "Legacy Fall 2005.FA.03" (PDF). Mtsinaifoundation.org ... and was Chair of the Publications Committee of the International Cytokine and Interferon Society from 2010 to 2016. 1990: ... President of the International Society for Interferon and Cytokine Research 2005: Maurice Saltzman Award, The Mt Sinai Health ...
*  Interleukin 7
IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a ... This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell ... This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory ... A human study of IL-7 in patients with cancer demonstrated that administration of this cytokine can transiently disrupt the ...
*  Interleukin-7 receptor-α
IL7R-α is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and Thymic Stromal Lymphopoietin ... Appasamy PM (1999). "Biological and clinical implications of interleukin-7 and lymphopoiesis". Cytokines Cell. Mol. Ther. 5 (1 ...
*  Myeloblast
The stimulation by G-CSF and other cytokines triggers maturation, differentiation, proliferation and cell survival. It is found ... "Hematopoietic cytokines". Blood. 111 (2): 485-491. doi:10.1182/blood-2007-03-079681. ISSN 0006-4971. PMC 2200848 . PMID ...
*  IL1A
Dinarello CA (2001). "IL-1α". In Durum SK, Oppenheim JJ, Feldmann M. Cytokine reference: a compendium of cytokines and other ... Feldmann M, Saklatvala J (2001). "Proinflammatory cytokines". In Durum SK, Oppenheim JJ, Feldmann M. Cytokine reference: a ... "TLR-signaling and proinflammatory cytokines as drivers of tumorigenesis". Cytokine. 89: 127-135. doi:10.1016/j.cyto.2016.01.021 ... These data suggest that IL-1α is as an epidermal cytokine. IL1A has been shown to interact with HAX1, and NDN. Although there ...
*  1833 in science
177-8. ISBN 978-0-19-858170-3. Tedgui, Alain; Mallat, Ziad (2006). "Cytokines in Atherosclerosis". Physiological Reviews. ...
*  Psoriasis
Kunz M, Ibrahim SM (2009). "Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity". ... Baliwag, Jaymie; Barnes, Drew H.; Johnston, Andrew (2015-06-01). "Cytokines in psoriasis". Cytokine. Skin Disease, Immune ... therapy can reduce the number of dendritic cells and favors a Th2 cell cytokine secretion pattern over a Th1/Th17 cell cytokine ... Other cytokines such as IL-17 and IL-22 also have been targets for inhibition as they play important roles in the pathogenesis ...
*  Interleukin 17
... A (IL-17 or IL-17A) is a pro-inflammatory cytokine. This cytokine is produced by a group of T helper cell known ... Baliwag J, Barnes DH, Johnston A (2015). "Cytokines in psoriasis". Cytokine. 73 (2): 342-50. doi:10.1016/j.cyto.2014.12.014. ... IL-17 induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including ... The release of cytokines causes many functions, such as airway remodeling, a characteristic of IL-17 responses. The increased ...
*  Fibromyalgia
A systematic review found most cytokines levels were similar in patients and controls, except for IL-1 receptor antagonist, IL- ... One study found increased levels of pro-inflammatory cytokines in fibromyalgia, which may increase sensitivity to pain, and ... Rodriguez-Pintó, Ignasi; Agmon-Levin, Nancy; Howard, Amital; Shoenfeld, Yehuda (1 October 2014). "Fibromyalgia and cytokines". ... Uçeyler, Nurcan; Häuser, Winfried; Sommer, Claudia (28 October 2011). "Systematic review with meta-analysis: cytokines in ...
*  Nancy Rothwell
More recently she has carried out pioneering studies of the role of cytokines and other components of the immune system within ... She demonstrated the key role of specific cytokines and the hormone leptin in the integration and regulation by the brain of ... She was the first to show that the cytokine IL-1 mediates ischaemic brain damage, challenging the view that immune or ... Her current research focusses on the role of inflammation in brain disease and has identified the role of the cytokine ...