Cytokine-induced killer cells (CIK) cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) ... These NK cells referred to as cytokine induced memory-like natural killer cells are induced using cytokines, most commonly a ... Natural killer cell Natural killer T cell Lymphokine-activated killer cell Interleukin Cancer immunotherapy Schmidt-Wolf, IG; ... CIK cells is distinctive from that of natural killer cells or LAK cells because they can lyse cells that NK cells and LAK cells ...

September 2016). "Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia". ... Natural killer cells (NK cells) and macrophages play a major role in clearance of senescent cells. Natural killer cells ... NK cells are thought to be an important cell type in this process. These cells are known as "uterine NK cells" (uNK cells) and ... killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer ...

"Psychosocial modulation for cytokine-induced natural killer cell activity in older adults" (PDF). Psychosomatic Medicine. 58 (3 ... and persistent alterations in the natural killer cell response to cytokines in older adults" (PDF). Health Psychology. 13 (4): ... The caregivers also had higher EBV antibody titres and lower percentages of T cells and TH cells. Caregiving has also been ... September-October 2004). "Differential immune cell chemotaxis responses to acute psychological stress in Alzheimer's caregivers ...

Most clinical trials with NKT cells have been performed with cytokine-induced killer cells (CIK). Cytotoxic T cell (killer T ... Natural killer T cells should neither be confused with natural killer cells nor killer T cells (cytotoxic T cells). The term " ... cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells. Many of these cells ... "Cytokine-induced killer cell (CIK) in cancer immunotherapy: report of the international registry on CIK cells (IRCC)". J Cancer ...

... dendritic cells and natural killer cells. TWEAK can induce apoptosis via multiple pathways of cell death in a cell type- ... This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of ... and Fas ligand mediate monocyte death induced by autologous lupus T cells". Journal of Immunology. 169 (10): 6020-9. doi: ... "Multiple pathways of TWEAK-induced cell death". Journal of Immunology. 168 (2): 734-43. doi:10.4049/jimmunol.168.2.734. PMID ...

... an effector B cell in the immune system Effector T cells, T cells that actively respond to a stimulus Cytokine-induced killer ... the primary effector cell involved in the development of asthma As an effector cell, cytokine-induced killer cells can ... Cytokine-Induced killer (CIK) cells are important because harmful cells that do not contain MHC cannot be traced and removed by ... characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells". ...

Cells that bind and migrate in response to CXCL16 include several subsets of T cells, and natural killer T (NKT) cells. CXCL16 ... Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha. The gene for human CXCL16 is located on ... CXCL16 is produced by dendritic cells found in the T cell zones of lymphoid organs, and by cells found in the red pulp of the ... "Microbial exposure during early life has persistent effects on natural killer T cell function". Science. 336 (6080): 489-493. ...

Natural killer cells directly kill senescent cells, and produce cytokines which activate macrophages which remove senescent ... Immune system cells can be recruited by SASP to senescent cells, after which the SASP from the senescent cells can induce the ... Senolytic drugs which induce apoptosis in senescent cells rely on phagocytic immune system cells to remove the apoptosed cells ... Natural killer cells (NK cells) and macrophages play a major role in clearance of senescent cells. ...

This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is ... Although IL-15 mRNA can be found in many cells and tissues including mast cells, cancer cells or fibroblasts, this cytokine is ... This cytokine is also implicated in NK cell development. In rodent lymphocytes, IL-15 prevents apoptosis by inducing BCL2L1/BCL ... dendritic cells (DC), keratinocytes, fibroblasts, myocyte and nerve cells. As a pleiotropic cytokine, it plays an important ...

HIV-1 induces cardiomyopathy by cardiomyocyte invasion and gp120,Tat, and cytokine apoptotic signaling. Cardiovasc Toxicol 2004 ... TNF-α is produced by infected macrophages and the interaction between dendritic cells presenting the antigen to CD8 (T Killer ... Matsumori A. Cytokines in myocarditis and cardiomyopathy. Curr Opin Cardiol 1996;11:302-9. Finkel MS, Oddis CV, Jacob TD, et al ... Essential role of HIV-1 infected and cyclooxygenase 2 activated macrophages and T cells in HIV type 1 myocarditis. AIDS Res Hum ...

... including cells lysis and secretion of pro-inflammatory cytokines. LTi cells (lymphoid tissue-inducing cells) are a ... These receptors are commonly found on natural killer cells and some subpopulations of innate and adaptive cells. They are ... This is supported by the fact that ILC3 cells mirror the phenotype of Th17 cells, and a subset of ILC3 cells has also been ... August 2018). "Innate Lymphoid Cells: 10 Years On". Cell. 174 (5): 1054-1066. doi:10.1016/j.cell.2018.07.017. PMID 30142344. ...

XIAP-deficient individuals also produce low numbers of natural killer cells, a feature shared with XLP1 patients, which leads ... which activates cell-activating signaling pathways. In an XLP patient, the defects in SAP cause these receptors to induce an ... and Cytotoxic T cells that typically eliminate EBV infection, leading to cytokine overproduction and tissue damage. The term " ... Pende D, Meazza R, Marcenaro S, Aricò M, Bottino C (July 2019). "2B4 dysfunction in XLP1 NK cells: More than inability to ...

... cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/ ... "IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like ... cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells". ... Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) ...

... stimulates natural killer T cell lymphocytes to induce apoptosis in the neutrophils and eosinophil of inflamed tissues; and ... Microglia cells: inhibit the release of pro-inflammatory cytokines by this central nervous system type of macrophage. Mast ... gamma delta T cells, and Natural killer T cells. The cited cells then proceeded to neutralize invading organisms, limit tissue ... T cells, mast cells, and dendritic cells as well as in vascular tissue; GPR32 (also termed the RvD1 receptor or DRV1) is ...

Maghazachi AA, Al-Aoukaty A, Schall TJ (February 1996). "CC chemokines induce the generation of killer cells from CD56+ cells ... natural-killer (NK) cells, dendritic cells and mastocytes. With the help of particular cytokines (i.e., IL-2 and IFN-γ) that ... CCL5 also induces the proliferation and activation of certain NK cells to form CHAK (CC-Chemokine-activated killer) cells. It ... CCR5 is presented on the surface of T-cells, smooth muscle endothelial cells, epithelial cells, parenchymal cells and other ...

Alaska Cytokine-induced killer cell, a subset of natural killer T cells Crypto Ignition Key, or KSD-64, a security token ...

IL-23 expression by dendritic cells is further induced by thymic stromal lymphopoietin, a proallergic cytokine expressed by ... which actively secrete Th17 cytokines upon IL-23 stimulation. Natural killer cells also express the IL-23 receptor. They ... IL-23 is an inflammatory cytokine. It has been shown to be a key cytokine for T helper type 17 cell (Th17 cell) maintenance and ... Innate lymphoid cells and γδ T cells also produce IL-23. B cells produce IL-23 through B cell antigen receptor signaling. ...

The expression of ZBTB32 is induced by inflammatory cytokines and promotes proliferation of natural killer cells. Zbtb32 ... ZBTB32 is highly expressed in spermatogonial stem cells, in hematopoietic stem and progenitor cells, in diffuse large B-cell ... Beaulieu AM, Madera S, Sun JC (2015). "Molecular Programming of Immunological Memory in Natural Killer Cells". Crossroads ... Cell. 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685. Ikeda R, Yoshida K, Inoue I (May 2007). " ...

Bacteria and cytokines induce low level of PGLYRP2 expression in the skin and gastrointestinal and oral epithelial cells, and ... also in intestinal intraepithelial T lymphocytes, dendritic cells, NK (natural killer) cells, and inflammatory macrophages. ... Bacteria and cytokines induce expression of PGLYRP2 in epithelial cells through the p38 mitogen activated protein kinase (MAPK ... February 2009). "PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation". Cell Host & ...

... including an increase in degranulation of natural killer cells, an increase in T cell proliferation, and the expansion and ... An analysis of immunomodulating effect induced by azoximer bromide proved its stimulating activity on proinflammatory cytokines ... Study of interaction between the polyoxidonium immunomodulator and the human immune system cells. Int Immunopharmacol 2004;4: ... Toptygina A, Semikina E, Alioshkin V. Influence of an immunopotentiator polyoxidonium on cytokine profile and antibody ...

Sendai virus can induce the production of many cytokines that enhance cellular immune responses against cancer cells. SeV ... The increased concentration of ICAM-1 on the cells surface increases the vulnerability of these cells to natural killer cells. ... SeV induces the production of B cell-activating factor by monocytes and by some other cells. Heat-inactivated SeV virus induces ... SeV induces the production of B cell-activating factor by monocytes and by some other cells. Heat-inactivated SeV virus induces ...

... phagocytose incoming antigen and to secrete proinflammatory cytokines that induce inflammation and recruit other immune cells ... Macrophages also recruit other immune cells such as monocytes, dendritic cells, natural killer cells, basophils, eosinophils, ... Along with dendritic cells, macrophages help activate natural killer (NK) cells through secretion of type I interferons (IFN-α ... Macrophages are a type of repairing cell that devour dead cells and pathogens, and trigger other immune cells to respond to ...

Natural killer cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy. Blood ... Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12. Proc Natl Acad ... He demonstrated that treatment with immunocytokines, which are antibody-cytokine fusion proteins, is effective in this model ... Anti-neuroblastoma effect of ch14.18 antibody produced in CHO cells is mediated by NK-cells in mice. Mol Immunol 2005;42:1311-9 ...

Bacteria and cytokines induce low level of PGLYRP2 expression in the skin and gastrointestinal epithelial cells, intestinal ... intraepithelial T lymphocytes, dendritic cells, NK (natural killer) cells, and inflammatory macrophages. Some mammals, e.g. ... Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death". Cells. 9 (2): 488. doi:10.3390/cells9020488. ... Bacterial killing by these PGRPs does not involve cell membrane permeabilization, cell wall hydrolysis, or osmotic shock, but ...

IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, ... Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is a gel-like mucin product of goblet cells. Interleukin-13 induces ... April 1993). "Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function". Proceedings of the ... Most normal cells, such as immune cells or endothelial cells, express very low or undetectable levels of IL-13 receptors. ...

... activated natural killer cells; and peritoneal macrophages. Pathogen-induced necrosis programs in cells with immunological ... Pathological conditions are characterized by inadequate secretion of cytokines. Nitric oxide (NO) and reactive oxygen species ( ... January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death and ... and other trophic factors and induces massive necrotic death of endothelial cells and non-proliferating cells of surrounding ...

In addition, they can produce cytokines IL-12, IL-6 and TNF-α as well, helping to recruit other immune cells to the site of ... For example, the secretion of type 1 interferon triggers natural killer cells to produce IFNγ while also activating the ... A pDC's ability to stimulate T cells is heightened following maturation. As mentioned earlier, maturation also induces the ... Plasmacytoid dendritic cells (pDCs) are a rare type of immune cell that are known to secrete large quantities of type 1 ...

"Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells". ... See the Natural killer cell page for further information on NK cells in tumor surveillance. ILC1s influence the tumor ... IL-13 also activates T cells, inducing further physiological responses to expel the parasite. T cells stimulate goblet cell ... Retinoic acid, produced by many cell types, such as nerve cells, dendritic cells, and stromal cells, favours the ...

... dendritic cells, and invariant natural killer (iNK) T-cells exhibited greater control of fungal growth and protection against ... In the case of mucosal candidiasis, the cells that produce cytokine IL-17 are extremely important in maintaining innate ... Pattern recognition receptors (PRRs) play an important role in inducing an immune response by recognizing specific fungal ... Infecting C. neoformans cells are usually phagocytosed by alveolar macrophages in the lung. The invading C. neoformans cells ...

Active CD4+T cells activate the Natural-killer cells, and also CD4+T cells activate the humoral immune response and also ... memory T helper 1 cell and T helper 17 cells and cytokine responses are observed in patients received with the whole cell ... "Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen". Blood. 88 (1): 41-48. doi:10.1182/blood. ... These dendritic cells facilitate the T-cell response by combining with CD8+ T cells. The whole-cell pneumococcal vaccine ...