*Cytochrome b5 reductase

2 ferrocytochrome b5 The following four human genes encode cytochrome-b5 reductases: CYB5R1 CYB5R2 CYB5R3 CYB5R4 Cytochrome b5 ... Cytochrome-b5 reductase (also known as methemoglobin reductase) is a NADH-dependent enzyme that converts methemoglobin to ... It contains FAD and catalyzes the reaction: NADH + H+ + 2 ferricytochrome b5 = NAD+ + ... Methemoglobinemia Reductase Cytochrome-B(5) Reductase at the US National Library of Medicine Medical Subject Headings (MeSH) ...

*Cytochrome b5

2 ferricytochrome b5 + H2O P450-containing systems Cytochrome b5, type A Lederer, F. (1994). "The cytochrome b5-fold: an ... EC 1.6.2.2 cytochrome-b5 reductase NADH + H+ + 2 ferricytochrome b5 → NAD+ + 2 ferrocytochrome b5 EC 1.10.2.1 L-ascorbate- ... The family of cytochrome b5-like proteins includes (besides cytochrome b5 itself) hemoprotein domains covalently associated ... PDB: 1B5A​ - Solution structure of rat cytochrome b5 (form A) PDB: 1B5B​ - Solution structure of rat cytochrome b5 (form B) PDB ...

*L-ascorbate-cytochrome-b5 reductase

In enzymology, a L-ascorbate-cytochrome-b5 reductase (EC 1.10.2.1) is an enzyme that catalyzes the chemical reaction L- ... This enzyme is also called ascorbate-cytochrome b5 reductase. Everling FB, Weis W, Staudinger H (1969). "[Kinetic studies on an ... ferrocytochrome b5 + H+ Thus, the two substrates of this enzyme are L-ascorbate and ferricytochrome b5, whereas its 3 products ... The systematic name of this enzyme class is L-ascorbate:ferricytochrome-b5 oxidoreductase. ...

*Cytochrome b5, type A

Cytochrome b5, form A (gene name CYB5A), is a human microsomal cytochrome b5. Cytochrome b5 is a membrane bound hemoprotein ... 1974). "Structural studies of cytochrome b5. 3. Sequential studies on human liver cytochrome b5". J. Biochem. 74 (5): 985-1002 ... cytochrome b5 reductase". J. Biol. Chem. 265 (35): 21709-13. PMID 2123873. Ozols J (1989). "Structure of cytochrome b5 and its ... "Chromosomal localization of a cytochrome b5 gene to human chromosome 18 and a cytochrome b5 pseudogene to the X chromosome". ...

*CYB5R1

... at Glu44 and Glu56 of cytochrome b5 on the protein's stabilization and interaction between cytochrome c and cytochrome b5". ... "Entrez Gene: CYB5R1 cytochrome b5 reductase 1". Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, ... NADH-cytochrome b5 reductase 1 is an enzyme that in humans is encoded by the CYB5R1 gene. The CYB5R1 gene is located on the 1st ... "NADH-cytochrome b5 reductase 1". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Human CYB5R1 genome location and ...

*CYB5R4

Cytochrome b5 reductase 4 is an enzyme that in humans is encoded by the CYB5R4 gene. NCB5OR is a flavohemoprotein that contains ... "Entrez Gene: CYB5R4 cytochrome b5 reductase 4". Human CYB5R4 genome location and CYB5R4 gene details page in the UCSC Genome ... functional domains found in both cytochrome b5 (CYB5; MIM 250790) and CYB5 reductase (DIA1; MIM 250800).[supplied by OMIM] ... "Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells". Proc Natl Acad Sci U S A. ...

*CYB5R2

... cytochrome b5 reductase 2". Zhu H, Qiu H, Yoon HW, Huang S, Bunn HF (December 1999). "Identification of a cytochrome b-type NAD ... Cytochrome b5 reductase 2 is an enzyme that in humans is encoded by the CYB5R2 gene. GRCh38: Ensembl release 89: ... 2005). "Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in ... 1999). "Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells". Proc. Natl. Acad. ...

*Nitric oxide dioxygenase

Electron donors may include ascorbate, cytochrome b5 or ferredoxin reductase. The catalytic NO dioxygenation can be written in ... Other proteins that may act as NODs include mammalian microsomal cytochrome P450(s) and a novel O2-binding cytochrome b from ... a novel cytochrome with NO dioxygenase activity. Although the biological function of SHP has yet to be identified, SHP has been ... and cytochrome oxidase, the last enzyme in the respiratory electron transport chain of mitochondria. Additionally NO, with its ...

*PGRMC1

... shares key structural motifs with cytochrome b5. PGRMC1 binds and activates P450 proteins, which are important in drug, ... Mifsud W, Bateman A (2002). "Membrane-bound progesterone receptors contain a cytochrome b5-like ligand-binding domain". Genome ... Debose-Boyd RA (Feb 2007). "A helping hand for cytochrome p450 enzymes". Cell Metabolism. 5 (2): 81-3. doi:10.1016/j.cmet. ... Crudden G, Loesel R, Craven RJ (2005). "Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human ...

*Methylsterol monooxygenase

H2O Methylsterol monooxygenase requires cytochrome b5. Rahier, A.; Smith, M.; Taton, M. (1997). "The role of cytochrome b5 in 4 ... Cytochrome b5-dependence of 4-methyl sterol oxidase". J. Biol. Chem. 256 (10): 4822-4826. PMID 7228857. Brady, D.R.; Crowder, R ... "Affinity chromatography of microsomal enzymes on immobilized detergent-solubilized cytochrome b5". J. Biol. Chem. 261 (8): 3790 ... Evidence against participation of cytochrome P-450". J. Biol. Chem. 243 (19): 4966-4972. PMID 4234469. Miller, W.L.; Kalafer, M ...

*Phenazopyridine

"Phenazopyridine induced methaemoglobinaemia associated with decreased activity of erythrocyte cytochrome b5 reductase". Journal ...

*Stearoyl-CoA 9-desaturase

Oshino N, Imai Y, Sato R (January 1971). "A function of cytochrome b5 in fatty acid desaturation by rat liver microsomes". J. ... ferrocytochrome b5, O2, and H+, whereas its 3 products are oleoyl-CoA, ferricytochrome b5, and H2O. This enzyme belongs to the ... The systematic name of this enzyme class is stearoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating). Other ... It catalyzes the chemical reaction stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ ⇌ {\displaystyle \rightleftharpoons } oleoyl ...

*Flavoprotein pyridine nucleotide cytochrome reductases

... cytochrome b5 reductases, cytochrome P450 reductases, sulphite reductases, nitric oxide synthases, phthalate dioxygenase ... Iwanaga S, Miyata T, Yubisui T, Tamura M, Takeshita M (1986). "Complete amino acid sequence of NADH-cytochrome b5 reductase ... Flavoprotein pyridine nucleotide cytochrome reductases catalyse the interchange of reducing equivalents between one-electron ... A family of flavoprotein pyridine nucleotide cytochrome reductases". J. Biol. Chem. 266 (35): 23542-23547. PMID 1748631. ...

*CMP-N-acetylneuraminate monooxygenase

Kozutsumi Y, Kawano T, Yamakawa T, Suzuki A (November 1990). "Participation of cytochrome b5 in CMP-N-acetylneuraminic acid ... 2 ferricytochrome b5 + H2O The 4 substrates of this enzyme are CMP-N-acetylneuraminate, ferrocytochrome b5, O2, and H+, whereas ... The systematic name of this enzyme class is CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl- ... 2 ferrocytochrome b5 + O2 + 2 H+ ⇌ {\displaystyle \rightleftharpoons } CMP-N-glycoloylneuraminate + ...

*CYB5R3

"Characterization of the covalent cross-links of the active sites of amidinated cytochrome b5 and NADH:cytochrome b5 reductase ... "Modification and identification of cytochrome b5 carboxyl groups involved in protein-protein interaction with cytochrome b5 ... "Entrez Gene: CYB5R3 cytochrome b5 reductase 3". ]Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, ... NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. The CYB5R3 gene is located on the ...

*CYP17A1

... cytochrome b5 (CYB5) and phosphorylation. Cytochrome b5 acts as a facilitator for 17,20 lyase activity of CYP17A1 and can ... Pandey AV, Miller WL (April 2005). "Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of ... This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are generally regarded ... "Entrez Gene: CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1". Ma YN, Cao CY, Wang QW, Gui WJ, Zhu GN (October ...

*MTRR (gene)

MTR reactivation can also be NADPH dependent involving two redox proteins, soluble cytochrome b5 and reductase 1. However, this ... Flavoprotein pyridine nucleotide cytochrome reductases, including FAD catalyse the interchange of reducing equivalents (H+ or ...

*Oxidoreductase FAD-binding domain

To date, the 3D-structures of the flavoprotein domain of Zea mays nitrate reductase and of pig NADH:cytochrome b5 reductase ... Miki K, Nishida H, Inaka K, Yamanaka M, Kaida S, Kobayashi K (1995). "Crystal structure of NADH-cytochrome b5 reductase from ...

*Cytochrome P450

Cytochrome b5 (cyb5) can also contribute reducing power to this system after being reduced by cytochrome b5 reductase (CYB5R). ... A second electron is transferred, from either cytochrome P450 reductase, ferredoxins, or cytochrome b5, reducing the Fe-O2 ... Cytochrome P450, B-class InterPro: IPR002397 Cytochrome P450, mitochondrial InterPro: IPR002399 Cytochrome P450, E-class, group ... CYB5R/cyb5/P450 systems, in which both electrons required by the CYP come from cytochrome b5. FMN/Fd/P450 systems, originally ...

*Hippocalcin-like protein 1

"Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner". J ...

*Ellipticine

... oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5". ... DNA damage results from the formation of covalent DNA adducts following enzymatic activation of ellipticine by with cytochromes ...

*Carroll Williams

Williams was the first to isolate juvenile hormone and ecdysone, and discovered cocoonase and cytochrome b5, as well as the " ...

*Flavonoid 3',5'-hydroxylase

"A cytochrome b5 is required for full activity of flavonoid 3′, 5′-hydroxylase, a cytochrome P450 involved in the formation of ...

*Bloodstain pattern analysis

When met-Hb is formed in vivo it will be reduced back to Hb by reductase protein cytochrome b5, resulting in a small part (. ...

*P450-containing systems

... cytochrome b5 reductase (CBR; EC 1.6.2.2): The ability of the CBR/cytochrome b5 system to support P450 catalysis has been ... It was hypothesized that cytochrome b5 is involved in the transfer of the second electron to P450, either from CPR or from NADH ... FMN domain, ferredoxin or cytochrome b5 transfer electrons between the flavin reductase (protein or domain) and P450. While ... ferredoxin and cytochrome b5. These ubiquitous redox domains, in various combinations, are widely distributed in biological ...

*List of MeSH codes (D12.776)

... cytochromes b6 MeSH D12.776.422.220.187.249 - cytochromes b MeSH D12.776.422.220.187.500 - cytochromes b5 MeSH D12.776.422.220. ... cytochromes a MeSH D12.776.422.220.175.500 - cytochromes a1 MeSH D12.776.422.220.175.600 - cytochromes a3 MeSH D12.776.422.220. ... cytochromes c' MeSH D12.776.422.220.286.200 - cytochromes c1 MeSH D12.776.422.220.286.300 - cytochromes c2 MeSH D12.776.422.220 ... cytochrome p-450 cyp2e1 MeSH D12.776.422.220.453.040.972 - cytochrome p-450 cyp3a MeSH D12.776.422.220.453.085 - camphor 5- ...