*  Sulfur assimilation
... lyase it is associated as enzyme complex named cysteine synthase. The formation of cysteine is the direct coupling step between ... The thiol groups of the cysteine residues in proteins can be oxidized resulting in disulfide bridges with other cysteine side ... which are synthesized enzymatically by a constitutive phytochelatin synthase. The number of γ-glutamyl-cysteine residues in the ... where sulfide must be incorporated first in homocysteine then converted in two steps to cysteine. Cysteine is sulfur donor for ...
*  Low-sulfur diet
Methionine cannot be synthesized by humans, and cysteine synthesis requires a steady supply of sulfur.[citation needed] The ... Cystathionine β-synthase (CBS) deficiency is a serious disorder of transsulfuration which is managed with methionine restricted ... cysteine). Sulfur is an essential dietary mineral primarily because amino acids contain it. Sulphur is thus considered ... recommended daily allowance (RDA) of methionine (combined with cysteine) for adults is set at 13-14 mg kg-1 day-1 (13-14 mg per ...
*  Cysteine synthase
"Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry. 26 (10): 2699-2704. doi: ... In enzymology, a cysteine synthase (EC 2.5.1.47) is an enzyme that catalyzes the chemical reaction O3-acetyl-L-serine + ... cysteine synthetase, S-sulfocysteine synthase, 3-O-acetyl-L-serine:hydrogen-sulfide, and 2-amino-2-carboxyethyltransferase. ... "Enzymatic-synthesis of the neuroexcitatory amino-acid quisqualic by cysteine synthase". Phytochemistry. 25 (12): 2759-2763. doi ...
*  S-carboxymethylcysteine synthase
... adding thioglycolate S-carboxymethyl-L-cysteine-forming). This enzyme is also called S-carboxymethyl-L-cysteine synthase. It ... In enzymology, a S-carboxymethylcysteine synthase (EC 4.5.1.5) is an enzyme that catalyzes the chemical reaction 3-chloro-L- ... Kumagai H, Suzuki H, Shigematsu H, Tuchikura T (1989). "S-Carboxymethylcysteine synthase from Escherichia coli". Agric. Biol. ... whereas its two products are S-carboxymethyl-L-cysteine and chloride. This enzyme belongs to the family of lyases, specifically ...
*  Uracilylalanine synthase
"Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry. 26 (10): 2699-2704. doi: ... In enzymology, an uracilylalanine synthase (EC 2.5.1.53) is an enzyme that catalyzes the chemical reaction O3-acetyl-L-serine ... Ahmmad MAS; Maskall CS; Brown EG (1984). "Partial-purification and properties of willardiine and synthase activity from Pisum ... Other names in common use include O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine ...
*  Transferase
Cysteine synthase, for example, catalyzes the formation of acetic acids and cysteine from O3-acetyl-L-serine and hydrogen ... elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2". PLOS ONE. 8 (11): e80135. doi: ... Selenocysteine synthase, which was first added to the classification system in 1999, converts seryl-tRNA(Sec UCA) into ... An example of a prominent glycosyltransferase is lactose synthase which is a dimer possessing two protein subunits. Its primary ...
*  Enzyme promiscuity
Codexis). Another example is the possibility of using the promiscuous activities of cysteine synthase (cysM) towards ... promiscuity can be decreased as was the case of γ-humulene synthase (a sesquiterpene synthase) from Abies grandis that is known ... For example, if a tRNA synthases loaded an incorrect amino acid onto a tRNA, the resulting peptide would have unexpectedly ... Similar in reaction to tRNA synthases, the first subunit of tyrocidine synthetase (tyrA) from Bacillus brevis adenylates a ...
*  Cystathionine beta synthase
... cysteine synthase, L-serine hydro-lyase (adding homocysteine), methylcysteine synthase, serine sulfhydrase, and serine ... The lack of CBS in these tissues implies that these tissues are unable to synthesize cysteine and that cysteine must be ... Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes ... Methylcysteine synthase was assigned the EC number EC 4.2.1.23 in 1961. A side-reaction of CBS caused this. The EC number EC ...
*  Horizontal gene transfer
transfer of a cysteine synthase from a bacterium into phytophagous mites and Lepidoptera allowing the detoxification of ...
*  Listeria Hfq binding LhrC
... a putative cysteine synthase and sul, a putative dihydropteroate synthase. In Listeria monocytogenes four additional copies of ...
*  Beta-pyrazolylalanine synthase
"Evidence for identity of beta-pyrazolealanine synthase with cysteine synthase in watermelon: formation of beta-pyrazole-alanine ... Other names in common use include beta-(1-pyrazolyl)alanine synthase, beta-pyrazolealanine synthase, beta-pyrazolylalanine ... synthase (acetylserine), O3-acetyl-L-serine acetate-lyase (adding pyrazole), BPA-synthase, pyrazolealanine synthase, ... by cloned cysteine synthase in vitro and in vivo". Biochem. Biophys. Res. Commun. 197 (3): 1111-7. doi:10.1006/bbrc.1993.2592. ...
*  Transsulfuration pathway
... encoded cysteine synthase and the metZ or metY -encoded homocysteine synthase, respectively). Two transsulfurylation pathways ... Cystathionine γ-synthase (metB) which joins an activated homoserine ether (acetyl or succinyl) with cysteine to form ... with homocysteine to form cystathionine Not Cystathionine β-synthase which is a PLP enzyme type II cysteine biosynthesis from ... In Klebsiella pneumoniae the cystathionine β-synthase is encoded by mtcB, while the γ-lyase is encoded by mtcC. Humans are ...
*  Walker motifs
... and pyridoxal phosphate utilizing enzymes such as cysteine synthase. Upon nucleotide hydrolysis the loop does not significantly ... The conserved sequence of this motif is C-x(5)-R-[ST], where C and R denote cysteine and arginine residues respectively. The A- ... These include ATP synthase (α and β subunits), myosin, transducin, helicases, kinases, AAA proteins, G-proteins, RecA, protein ... and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold". EMBO ...
*  Legionella jordanis
Small amounts of biosynthetic enzymes L-cysteine synthase and acetyltransferase were detected in L. jordanis and L. pneumophila ...
*  TRNA pseudouridine32 synthase
Ramamurthy, V.; Swann, S.L.; Spedaliere, C.J.; Mueller, E.G. (1999). "Role of cysteine residues in pseudouridine synthases of ... TRNA pseudouridine32 synthase (EC 5.4.99.28, RluA, pseudouridine synthase RluA, Pus9p, Rib2/Pus8p) is an enzyme with systematic ... TRNA pseudouridine32 synthase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ... Spedaliere, C.J.; Hamilton, C.S.; Mueller, E.G. (2000). "Functional importance of motif I of pseudouridine synthases: ...
*  MT-ATP8
"The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and ... ATP synthase protein 8 is a subunit of mitochondrial ATP synthase. Subunit 8 differs in sequence between Metazoa, plants and ... The ATP synthase protein 8 of human and other mammals is encoded in the mitochondrial genome by the MT-ATP8 gene. When the ...
*  Chagas disease
These include inhibitors of oxidosqualene cyclase and squalene synthase, cysteine protease inhibitors, dermaseptins collected ... Urbina JA, Concepcion JL, Rangel S, Visbal G, Lira R (2002). "Squalene synthase as a chemotherapeutic target in Trypanosoma ... Engel JC, Doyle PS, Hsieh I, McKerrow JH (August 1998). "Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi ...
*  List of MeSH codes (D08)
... cysteine synthase MeSH D08.811.913.225.300 --- dihydropteroate synthase MeSH D08.811.913.225.400 --- ... riboflavin synthase MeSH D08.811.913.225.825 --- spermidine synthase MeSH D08.811.913.225.912 --- spermine synthase MeSH ... glutamate-cysteine ligase MeSH D08.811.464.259.850.500 --- glutathione synthase MeSH D08.811.464.263.200 --- amino acyl-trna ... nitric oxide synthase type i MeSH D08.811.682.664.500.772.500 --- nitric oxide synthase type ii MeSH D08.811.682.664.500.772. ...
*  L-3-cyanoalanine synthase
In enzymology, a L-3-cyanoalanine synthase (EC 4.4.1.9) is an enzyme that catalyzes the chemical reaction L-cysteine + hydrogen ... beta-cyano-L-alanine synthase, and L-cysteine hydrogen-sulfide-lyase (adding HCN). This enzyme participates in cyanoamino acid ... The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide L-3-cyanoalanine-forming ... Purification and properties of the beta-cyanolanine synthase of blue lupine". J. Biol. Chem. 244 (10): 2632-40. PMID 5769995. ...
*  Hydrogen sulfide
... is derived from cysteine by the enzymes cystathionine beta-synthase, cystathionine gamma-lyase, and 3- ...
*  Morpheein
"Solvent-Accessible Cysteines in Human Cystathionine β-Synthase: Crucial Role of Cysteine 431 inS-Adenosyl-l-methionine Binding ... An example of such a conformational disease is ALAD porphyria, which results from a mutation of porphobilinogen synthase that ... The one protein that is established to function as a morpheein is porphobilinogen synthase, though there are suggestions ... An inhibitor of porphobilinogen synthase with this mechanism of action has been documented. The morpheein model of allosteric ...
*  Ovothiol A
It is synthesized by the addition and oxidation of cysteine to histidine by 5-histidylcysteine sulfoxide synthase, followed by ...
*  HCCS (gene)
"Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme ... 2006). "Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin ... "Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects ... "Conserved residues of the human mitochondrial holocytochrome c synthase mediate interactions with heme". Biochemistry. 53 (32 ...
*  Ketoacyl synthase
The characteristic reaction of β-ketoacyl-ACP synthase III is malonyl-ACP + acetyl-CoA => acetoacyl-ACP + CO2 + CoA. Cysteine, ... the two most common 3-ketoacyl-ACP synthase I and synthase II. 3-Ketoacyl-ACP synthase I (E.C. 2.3.1.41) is involved in the ... The dominant enzyme in the KS1 family is 3-ketoacyl-ACP synthase III (KAS III), also known as 3-oxoacyl-ACP synthase III and β- ... Chalcone synthase (E.C. 2.3.1.74), also known as naringenin-chalcone synthase, is responsible for the reaction: 3 malonyl-CoA ...
*  GMP synthase (glutamine-hydrolysing)
Identification of an essential active site cysteine". J. Biol. Chem. 270 (40): 23450-5. doi:10.1074/jbc.270.40.23450. PMID ...
*  Chromosome 7 (human)
... scavenger receptor cysteine rich family member with 4 domains STEAP1: six transmembrane epithelial antigen of the prostate 1 ... encoding enzyme Alpha-aminoadipic semialdehyde synthase, mitochondrial ARHGEF35: encoding protein Rho guanine nucleotide ...
*  Methionine
Two methionine synthases are known, one cobalamin (vitamin B12) dependent and one independent. The pathway utilising cysteine ... Homocysteine can be converted to cysteine. (5) Cystathionine-β-synthase (a PLP-dependent enzyme) combines homocysteine and ... Together with cysteine, methionine is one of two sulfur-containing proteinogenic amino acids. Excluding the few exceptions ... This is in contrast to cysteine residues, where the thiol group has a catalytic role in many proteins. The thioether does ...