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*  Cyclophosphamide
... is a pregnancy category D drug and causes birth defects. First trimester exposure to cyclophosphamide for the ... "cyclophosphamide - definition of cyclophosphamide in English from the Oxford dictionary". OxfordDictionaries.com. Retrieved ... For example, systemic lupus erythematosus with severe lupus nephritis may respond to pulsed cyclophosphamide. Cyclophosphamide ... Cyclophosphamide was approved for medical use in the United States in 1959. It is on the World Health Organization's List of ...
*  DMOZ - Health: Pharmacy: Drugs and Medications: C: Cyclophosphamide
Belongs to a class of drugs known as alkylating agents; it slows or stops the growth of cancer cells in the body. To be more effective it is sometimes used in combination with other chemotherapy medications. Used to treat lymphomas, multiple myeloma, leukemias, mycosis fungoides, neuroblastoma, ovarian carcinoma, retinoblastoma, breast cancer, Ewing's sarcoma, bronchogenic carcinoma, small cell lung carcinoma, and other types of cancer. Also known as Cytoxan.
*  Arteritis
Methylprednisolone, a glucocorticoid, is often used for pulse therapy; cyclophosphamide is an alternative. This method has been ... Immunosuppressive pulse therapy, such as with cyclophosphamide, has also demonstrated relief of symptoms associated with ... Commonly used cytotoxic agents include azathioprine, methotrexate, or cyclophosphamide. The dose of glucocorticoid medication ...
*  Paraquat
There have been some successful cases of using cyclophosphamide to treat paraquat poisoning. Death may occur up to 30 days ... doi:10.1046/j.0043-1737.2003.00356.x. Newstead CG (1996). "Cyclophosphamide treatment of paraquat poisoning". Thorax. 51: 659- ...
*  Timeline of cancer treatment development
Emadi A, Jones RJ, Brodsky RA (2009). "Cyclophosphamide and cancer: golden anniversary". Nat Rev Clin Oncol. 6 (11): 638-47. ... US FDA approves cyclophosphamide for chemotherapy of cancer 1960s - Introduction of laser therapy in treatment of cancer 1960 ... cyclophosphamide, and prednisone, cured advanced diffuse large B-cell lymphoma 1977 - US FDA approves tamoxifen for metatstatic ...
*  Male breast cancer
Chemotherapeutic options include: Cyclophosphamide plus methotrexate plus fluorouracil (CMF). Cyclophosphamide plus doxorubicin ...
*  Ch├ędiak-Higashi syndrome
Cyclophosphamide and prednisone have been tried. Vitamin C therapy has improved immune function and clotting in some patients. ...
*  Multiple sclerosis drug pipeline
Cyclophosphamide and beta-interferon has been tried on IFNbeta-unresponsive patients with success, but it is still under study ... 2006). "High-dose cyclophosphamide for moderate to severe refractory multiple sclerosis". Arch. Neurol. 63 (10): 1388-93. doi: ... Zipoli V, Portaccio E, Hakiki B, Siracusa G, Sorbi S, Pia Amato M (2007). "Intravenous mitoxantrone and cyclophosphamide as ... At this moment several therapies are under research: Cyclophosphamide (trade name Revimmune) is currently in Phase III for ...
*  Necrotizing vasculitis
Immunosuppressants such as cyclophosphamide and azathioprine may also be given. A systematic review of antineutrophil ... Current treatment of choice is cyclophosphamide. At least 2 out of 4 criteria yields sensitivity and specificity of 88 and 92 ...
*  Ovarian follicle activation
Chemotherapeutic agents, such as Cyclophosphamide, have been shown to activate the PI3K/PTEN/Akr pathway, which is the main ... "Cyclophosphamide triggers follicle activation and "burnout"; AS101 prevents follicle loss and preserves fertility". Science ...
*  4-Hydroxycyclophosphamide
... is in the class of oxazaphosphorine compounds, and is the main, active metabolite of cyclophosphamide ... The chemistry of the metabolites of cyclophosphamide. Curr Pharm Des. 1999 Aug;5(8):627-43. PMID 10469895. ...
*  Follicular dendritic cell sarcoma
Cyclophosphamide slows or stops cell growth cells. It targets cells that are rapidly dividing which include cancer cells that ... More importantly, the biological actions of cyclophosphamide are dose-dependent. At high doses it is very cytotoxic; its ... "Oral low-dose cyclophosphamide in metastatic hormone refractory prostate cancer (MHRPC)". Biomedecine & Pharmacotherapy. 58 (8 ... The CHOP regimen consists of Cyclophosphamide, Doxorubicin, Oncovin, and Prednisone (CHOP). They all exploit different pathways ...
*  Mafosfamide
The chemistry of the metabolites of cyclophosphamide. Curr Pharm Des. 1999 Aug;5(8):627-43. PMID 10469895 "Intrathecal ... Mafosfamide (INN) is an oxazaphosphorine (cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. It ...
*  CYC
Cyclophosphamide, an anti-neoplastic and immunosuppressant drug.. ...
*  Systemic scleroderma
Cyclophosphamide (SCOT) trial, is ongoing. Onishi A, Sugiyama D, Kumagai S, Morinobu A (July 2013). "Cancer incidence in ... June 2006). "Cyclophosphamide versus placebo in scleroderma lung disease". N. Engl. J. Med. 354 (25): 2655-66. doi:10.1056/ ... Active alveolitis is often treated with pulses of cyclophosphamide, often together with a small dose of steroids. The benefit ... The patient's white blood cells are destroyed with cyclophosphamide and rabbit antibodies against the white blood cells. Then ...
*  Perfosfamide
The chemistry of the metabolites of cyclophosphamide. Curr Pharm Des. 1999 Aug;5(8):627-43. PMID 10469895. ... Perfosfamide is an oxazaphosphorine compound, similar to mafosfamide and cyclophosphamide. Like those compounds it, is ...
*  Chronic inflammatory demyelinating polyneuropathy
Cyclophosphamide and rituximab seem to have some response. Mycophenolate mofetil may be of use in milder cases. Immunoglobulin ... and cyclophosphamide, a drug which reduces the function of the immune system. Ciclosporin has also been used in CIDP but with ...
*  Palpable purpura
Eg for wegner's treatment is steroids and cyclophosphamide. Mushlin, Stuart B.; Greene, Harry Lemoine (2009). Decision Making ...
*  Membranous glomerulonephritis
Chlorambucil Cyclosporine Tacrolimus Cyclophosphamide Mycophenolate mofetil Rituximab Perhaps the most difficult aspect of ... Recommended first line therapy often includes: cyclophosphamide alternating with a corticosteroid. Corticosteroids: They have ... cyclophosphamide, and chlorambucil therapy of membranous nephropathy". Semin. Nephrol. 23 (4): 355-61. doi:10.1016/S0270-9295( ... studies comparing treatments of membranous nephropathy showed that regimes comprising chlorambucil or cyclophosphamide, either ...
*  VAMP regimen
With the addition of cyclophosphamide this becomes C-VAMP. Vincristine, doxorubicin (Adriamycin), methotrexate and prednisone ...
*  Chronic lymphocytic leukemia
... fludarabine with cyclophosphamide) FR (fludarabine with rituximab) FCR (fludarabine, cyclophosphamide, and rituximab) CHOP ( ... The medications fludarabine, cyclophosphamide, and rituximab are typically the initial treatment in those who are otherwise ... An initial treatment regimen that contains fludarabine, cyclophosphamide, and rituximab (known as FCR) has demonstrated higher ... Alkylating agents approved for CLL include bendamustine and cyclophosphamide. Targeted therapy attacks cancer cells at a ...
*  Cogan syndrome
These immunosuppressive drugs include methotrexate, cyclophosphamide, cyclosporine or azathioprine. In some cases, combinations ...
*  Chemotherapy
Cyclophosphamide is a common cytotoxic drug used in this manner, and is often used in conjunction with total body irradiation. ... Cyclophosphamide is sometimes used to treat lupus nephritis, a common symptom of systemic lupus erythematosus. Dexamethasone ... Ntali S, Bertsias G, Boumpas DT (Jun 2011). "Cyclophosphamide and lupus nephritis: when, how, for how long?". Clinical Reviews ... Recently, bortezomid in combination with cyclophosphamide and dexamethasone has also shown promise as a treatment for AL ...
*  Doxorubicin
... cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone) and FAC (5-fluorouracil, adriamycin, cyclophosphamide). Doxil ( ... Commonly used doxorubicin-containing regimens are AC (adriamycin, cyclophosphamide), TAC (taxotere, AC), ABVD (Adriamycin, ... Doxorubicin and several chemotherapeutic drugs (including cyclophosphamide) cause dyspigmentation. Other groups of drugs that ... is approved in Europe and Canada for treatment of metastatic breast cancer in combination with cyclophosphamide, but has not ...
*  Autoimmune encephalitis
Relapsed required prolonged immunosuppression with MMF, AZA, or cyclophosphamide. Improves with immunotherapy and complete ... Moreover, despite immunosuppressive treatments including steroids, IVIg, cyclophosphamide, and rituximab, only 1 patient showed ... cyclophosphamide), and tumour removal. Most patients recovered or had mild deficits and some had severe deficits or died. It ... and second-line Rituximab and Cyclophosphamide, followed in many cases by steroid-sparing agents in the long-term. Sydenham's ...