A clinical pathway, also known as care pathway, integrated care pathway, critical pathway, or care map, is one of the main ... Maturen, Virginia; Van Dyck, Lisa (February 1996). "Using outcome-based critical pathways to improve documentation". Journal of ... Clinical pathways (integrated care pathways) can be seen as an application of process management thinking to the improvement of ... Clinical pathways can range in scope from simple medication utilization to a comprehensive treatment plan. Clinical pathways ...

This pathway plays a critical role in mediating immune defense against double-stranded DNA viruses. The innate immune system ... The cGAS-STING pathway is a component of the innate immune system that functions to detect the presence of cytosolic DNA and, ... The cGAS/STING pathway also has a role in tumor surveillance. In response to cellular stress, such as DNA damage, cells will ... The cGAS - STING pathway acts to detect cytosolic DNA and induce an immune response. Upon binding DNA, the protein cyclic GMP- ...

... canonical androgenic pathway that involves testosterone and/or androstenedione. The androgen backdoor pathways are critical ... Understanding these pathways is critical for the development of effective treatments for conditions related to androgen ... The pathway then proceeds the same way as the pathway that starts from 17-OHP, and can be summarized as: P4 → 5α-DHP → AlloP5 ... The pathway Auchus defined adds DHT to the terminus of the pathway described by Wilson et al. in 2003: 17-OHP → 17OHDHP → 5α- ...

The Notch signaling pathway was found to be critical mainly for neural progenitor cell (NPC) maintenance and self-renewal. In ... The Notch signaling pathway is a critical component of cardiovascular formation and morphogenesis in both development and ... The Notch pathway is essential for maintaining NPCs in the developing brain. Activation of the pathway is sufficient to ... Notably, this system allows multiple synthetic pathways to be engineered into a cell in parallel. The Notch signaling pathway ...

Use and evaluation of critical pathways in hospitals. Eff Clin Pract 2002; 5:114-119. De Luc K., Developing care pathways - the ... International survey on the use and dissemination of clinical pathways in 23 countries, Journal of Integrated Care Pathways, ... The European Pathway Association (E-P-A.org) is a European non-profit organisation which brings together researchers, managers ... The organisation works on the establishment of clinical care pathways in order to systematically plan and follow up a patient ...

Critical Pathways in Cardiology. 18 (4): 167-175. doi:10.1097/HPC.0000000000000189. PMID 31725507. S2CID 208036312. "A Doctor's ... "An Updated Healthcare System-Wide Clinical Pathway for Managing Patients With Chest Pain and Acute Coronary Syndromes". ...

Critical Pathways in Cardiology. 10 (10): 44-45. doi:10.1097/HPC.0b013e31820b887b. PMID 21562375. "UOTW #14 - Ultrasound of the ... Bromocriptine is being studied as another potential treatment option, due to its interference with the prolactin pathway which ... Thus, therapeutic interventions that block the prolactin pathway and prevent the generation of this fragment are being ...

Critical Pathways in Cardiology. 20 (3): 155-162. doi:10.1097/HPC.0000000000000256. ISSN 1535-2811. PMID 33606411. S2CID ... The training and career pathways for internists vary considerably across different countries. Many programs require previous ... Internists may work in many settings including outpatient clinics, inpatient wards, critical care units, and emergency ... Cardiovascular disease, dealing with disorders of the heart and blood vessels* Clinical cardiac electrophysiology Critical care ...

Critical Pathways in Cardiology. 5 (4): 187-90. doi:10.1097/01.hpc.0000249784.29151.54. PMID 18340236. Pearson, T. A. (2007). " ...

"The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection". ... The lectin pathway or lectin complement pathway is a type of cascade reaction in the complement system, similar in structure to ... The lectin pathway starts with mannose-binding lectin (MBL) or ficolin binding to certain sugars. In this pathway, mannose- ... Classical complement pathway Alternative complement pathway Mannan-binding lectin Wallis R, Mitchell DA, Schmid R, Schwaeble WJ ...

Critical Pathways in Therapeutic Intervention. Missouri: Mosby Inc. p. 262. ISBN 0-323-00105-X. "Nerve Injury (Neuropraxia, ...

Pathways Listening, Speaking, and Critical Thinking by MacIntyre. Douglas, Scott R. Academic Inquiry: Writing for Post- ... Robert Lowth (26 March 1794). A Short Introduction to English Grammar: With Critical Notes. Printed for J.J . Tourneisin - via ...

Barzilai, N; Huffman, DM; Muzumdar, RH; Bartke, A (June 2012). "The critical role of metabolic pathways in aging". Diabetes. 61 ... 2018). "Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older ... "Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans". PLOS Biol. 4 (4): e113. doi:10.1371/journal. ...

"Direct and indirect pathways of basal ganglia: a critical reappraisal". Nature Neuroscience. 17 (8): 1022-1030. doi:10.1038/nn. ... The second pathway, is called the direct (or Go) pathway and is excitatory. This pathway inhibits the GPi, resulting in the ... Two pathways emerge from the striatum. One pathway is called the indirect (or NoGo) pathway and is inhibitory. This projects to ... As of 2013 there was intense debate with regards to division of the circuit, pathway interactions, number of pathways and ...

"Direct and indirect pathways of basal ganglia: a critical reappraisal". Nature Neuroscience. 17 (8): 1022-1030. doi:10.1038/nn. ... The motor and oculomotor pathways are sometimes grouped into one motor pathway.) The five general pathways are organized as ... The short indirect pathway has been proposed to, in a direct push pull antagonism with the direct pathway, close the gate to ... However the speed of the direct pathway would not be concordant with the indirect pathway in this model leading to problems ...

The indirect pathway also receives excitatory input from various brain regions. Indirect pathway medium spiny neurons project ... Dopamine plays critical roles in the regulation of psychomotor functions in the brain (Bromberg-Martin et al., 2010; Cools, ... However, direct pathway medium spiny neurons mostly signal sequence initiation/termination and indirect pathway medium spiny ... D1-type MSNs of the direct pathway and D2-type MSNs of the indirect pathway. Most striatal MSNs contain only D1-type or D2-type ...

The Hippo pathway also has a critical role in stem cell and tissue specific progenitor cell self-renewal and expansion. The ... The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ ... The pathway takes its name from one of its key signaling components-the protein kinase Hippo (Hpo). Mutations in this gene lead ... The Hippo pathway consists of a core kinase cascade in which Hpo phosphorylates (Drosophila) the protein kinase Warts (Wts). ...

... constitute inquiry pathways that are explored using a critical incident approach. The initial starting conditions for each ... 11� Russell, D.B. & Ison, R.L. (2000) Enthusiasm: developing critical action for second-order R&D. In Ison, R.L. & Russell, D.B ... 13� Russell, D.B. & Ison, R.L. (2000) Enthusiasm: developing critical action for second-order R&D. In Ison, R.L. & Russell, D.B ... 10� Russell, D.B., Ison, R.L., Gamble, D.R. & Williams, R.K. (1989) A Critical Review of Rural Extension Theory and Practice. ...

Juliet J. Fall: Reading Claude Raffestin: pathways for a critical biography. In: Environment and Planning D: Society and Space ...

Smith appears on the albums Critical Mass (2005) and Pathways (2009). In 2017, he released his first album as leader, Kinfolk: ... 1 (ArtistShare, 2014) More Than Meets the Ear (ArtistShare, 2015) With Dave Holland Critical Mass (Dare2, 2006) Pathways (Dare2 ...

Hence binding site on protein are critical parts of signal transduction pathways. Types of ligands include neurotransmitters, ... Its regulation in glycolysis is imperative because it is the committing and rate limiting step of the pathway. PFK also ... This regulation efficiently conserves glucose reserves, which may be needed for other pathways. Citrate, an intermediate of the ... Binding sites incur functional changes in a number of contexts, including enzyme catalysis, molecular pathway signaling, ...

Chung, DC (2000). "The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis". Gastroenterology ... Both the β-catenin gene and the APC gene are involved in the same cell growth signalling pathway, but the APC gene is known to ...

Cilia defects adversely affect numerous critical developmental signaling pathways essential to cellular development. Other ...

A critical review of the evidence for biological pathways". American Psychologist. 58 (1): 53-63. doi:10.1037/0003-066X.58.1.53 ... A critical review of the evidence for biological pathways". American Psychologist. 58 (1): 53-63. doi:10.1037/0003-066x.58.1.53 ...

"A critical role for the mTORC2 pathway in lung fibrosis". PLOS ONE. 9 (8): e106155. Bibcode:2014PLoSO...9j6155C. doi:10.1371/ ... The mTORC2 pathways plays a crucial role in pathogenesis of lung fibrosis, and inhibitors of its active site such as ... Studies using mice with tissue-specific loss of Rictor, and thus inactive mTORC2, have found that mTORC2 plays a critical role ... Mendoza MC, Er EE, Blenis J (June 2011). "The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation". Trends in ...

... a critical enzyme in the cholesterol biosynthesis pathway". Clin. Genet. 75 (1): 19-29. doi:10.1111/j.1399-0004.2008.01099.x. ... Statin Pathway edit]] The interactive pathway map can be edited at WikiPathways: "Statin_Pathway_WP430". Squalene synthase (SQS ... FPP is an important metabolic intermediate in the mevalonate pathway that represents a major branch point in terpenoid pathways ... A tyrosine residue (Tyr-171) plays a critical role in this step by serving as a proton donor to facilitate abstraction of ...

... a critical enzyme in the cholesterol biosynthesis pathway". Clin. Genet. 75 (1): 19-29. doi:10.1111/j.1399-0004.2008.01099.x. ... The core biosynthetic route is via a polyketide synthase pathway from 10 acetates, 4 methyls of methionines, 1 succinate, and 1 ...

A number of specific decay pathways exist that recognize aberrant messages and promote their decapping. Nonsense mediated decay ... Critical Reviews in Biochemistry and Molecular Biology. 39 (4): 197-216. doi:10.1080/10409230490513991. PMID 15596551. S2CID ... Meyer, Sylke; Temme, Claudia; Wahle, Elmar (January 2004). "Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes". ...

A number of critical developmental signaling pathways essential to cellular development have been discovered. These are ... Signal transduction pathways involved include the Hedgehog signaling pathway and the Wnt signaling pathway. Dysfunctional cilia ... Cilia may thus be "viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes ... cilia are critical for: development homeostasis reproduction "Just as different genes can contribute to similar diseases, so ...

The cilia defects adversely affect "numerous critical developmental signaling pathways" essential to cellular development. The ...