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*  Autophagocytosis associated protein Atg3
It carries a highly characteristic conserved FLKF sequence motif. Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T (May ...
*  Homing endonuclease
The sequence LAGLIDADG is a conserved sequence of amino acids where each letter is a code that identifies a specific residue. ... H-N-H: These have a consensus sequence of approximately 30 amino acids. It includes two pairs of conserved histidines and one ... recognition sequences of 4 to 8 bp, homing endonucleases bind very long and in many cases asymmetric recognition sequences ... This sequence is directly involved in the DNA cutting process. Those enzymes that have only one motif work as homodimers, ...
*  HIPK2
... it contains three conserved sequences: a protein kinase domain, an interaction domain, a PEST sequence, and a YH domain. ... The human sequence shares a close similarity to a sequence from the genome of Caenorhabditis elegans. HIPKs also share a close ... The speckle retention sequence is necessary for HIPK2 function in transcription activation as deletion of this sequence ... The PEST sequence found in HIPK2 is also linked to protein degradation. HIPK2 activity can also be down regulated by the ...
*  CCDC92
However, based on interacting proteins, conserved sequences, and subcellular localization (nucleus), it can be discerned that a ... CCDC92 has conserved predicted phosphorylation sites at S211, S325, T21, T52, T122, Y130 and conserved glycosylation sites at ... The most highly conserved domain is the coiled-coil domain 92, which is amino acids 23-83 in humans. This region has no known ... This sequence is present in primarily proteins which are involved in reduction/oxidation reactions, and some bind to DNA. The ...
*  Saposin protein domain
In molecular biology a saposin protein domain is a region of the saposin protein that has a certain conserved sequence or ...
*  ARGLU1
Furthermore, ARGLU1 contains a long, highly evolutionarily conserved sequence known as an Ultraconserved Element (UCE) that is ...
*  Control of chromosome duplication
... but do not exhibit strong sequence similarity. In animals, no highly conserved sequence elements have been found to direct ... It was identified in S. cerevisiae by its ability to bind the conserved A and B1 elements of yeast origins. It is a conserved ... The ARS contains several specific sequence elements. One of these is the A element (ACS), an 11 bp consensus sequence rich in ... Still, presence of an ACS sequence is not sufficient to identify an origin of replication. Only about 30% of ACS sequences ...
*  MKI67IP
There are two conserved sequence motifs within the FHA Ki67 binding domain: TPVCTP and LERRKS, this domain binds to the ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... 2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724-31. doi:10.1038/ ...
*  Ribonuclease H
All RNases H have an active site centered on a conserved sequence motif composed of aspartate and glutamate residues, often ... the B and C subunits have no apparent homologs in prokaryotes and are poorly conserved at the sequence level even among ... It can also be used to cleave specific RNA sequences in the presence of short complementary segments of DNA. Highly sensitive ... However, the yeast B and C subunits have very low sequence identity to their homologs in other organisms, and the corresponding ...
*  Predictive medicine
On a protein level, structure is less conserved than sequence. Therefore, in many diseases, having the faulty gene still does ... However, comprehensive genetic testing (such as through the use of DNA arrays or full genome sequencing) allows for the ... Newborn screening Full genome sequencing Personalized medicine Molecular imaging Theranostics The Singularity "Predictive ...
*  MMP9
The propeptide domain is characterized by a conserved PRCGVPD sequence. The Cys within this sequence is known as the "cysteine ... A conserved methionine, which forms a unique "Met-turn" structure categorizes MMP9 as a metzincin. Three type II fibronectin ... The catalytic zinc is coordinated by three histidines from the conserved HEXXHXXGXXH binding motif. The other zinc atom and the ... the zinc-binding catalytic domain and the carboxyl-terminal hemopexin-like domain are conserved. Its primary structure ...
*  Amino acid
They are also used to summarise conserved protein sequence motifs. The use of single letters to indicate sets of similar ... This creates some sequences that do not appear in the genome. This characteristic can be taken advantage of and used to create ... These are added in sequence onto the growing peptide chain, which is attached to a solid resin support. The ability to easily ... This UAG codon is followed by a PYLIS downstream sequence. Aside from the 22 proteinogenic amino acids, many non-proteinogenic ...
*  HIV integration
The region of insertion contains a weakly conserved palindromic sequence. This strand transfer reaction is initiated as the HIV ... The sequence of binding of the LEDGF/p75, the host DNA, and the preintegration complex remains unclear. In one version, the ... Regardless of the sequence, it is believed that the presence of LEDGF/p75 results in the integrase dimers approaching each ... The binding takes place at specific sequences in the long terminal repeat regions. The integrase-HIV DNA complex is part of an ...
*  James E. Womack
RH mapping is an effective tool for building ordered maps of conserved sequences, derived from genes, thus integrating linkage ...
*  KH domain
The binding occurs in a cleft formed between alpha helix 1, alpha helix 2 the GXXG loop (contains a highly conserved sequence ... An evolutionarily conserved sequence of around 70 amino acids, the KH domain is present in a wide variety of nucleic acid- ... While both types share a minimal consensus sequence motif they have different structural folds. The type I KH domains have a ...
*  Small nucleolar RNA J26
J26 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D ...
*  Naked cuticle
The conserved sequence blocks, from N-terminal to C-terminal, are as follows: 1) a N-terminal membrane anchoring motif, which ... and a sequence between the third and fourth block that is highly conserved in Drosophila species but is neither present in the ... Nkd proteins consist of at least four well-conserved blocks of amino acid sequence interspersed by variable regions. ... For example, Nkd2 but not Nkd1 associates with the secreted EGF-family ligand TGF alpha via a sequence between the third and ...
*  Small nucleolar RNA SNORD15
U15 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D ... despite a significantly shorter sequence length, appear to be related. Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; ...
*  SnRNP
This Sm site is a conserved sequence of nucleotides in these snRNAs, typically AUUUGUGG (where A, U and G represent the ... The snRNA component of the snRNP gives specificity to individual introns by "recognizing" the sequences of critical splicing ... with highly conserved 5' splice sites and branch sites. This variant class of snRNPs includes: U11 snRNA, U12 snRNA, U4atac ...
*  Small nucleolar RNA R41
snoR41 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the ... The 18S methylation site is reported to be homologous to that targeted by U62 in humans but there appears to be little sequence ...
*  Small nucleolar RNA SNORD73
snoRNA U73 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) ... within the introns of ribosomal protein S3a and contains a 12 nucleotide region of complementarity to a conserved sequence in ...
*  CR2
... a segmentwise numerical designation is used for alternating regions of highly conserved sequence interspersed with nonconserved ... "Conserved Region 2" i.e. the Second conserved region. In some biological molecules e.g. Epstein-Barr virus EBNA-LP, Adenoviral ... CR2 usually means the second conserved region from the N terminus. This term "CR" i.e. conserved region has somewhat similar ...
*  FAM149A
There is a conserved HLR sequence motif found in DUF 3719. Below is an image showing the DUF3719 on FAM149A. From the Sanger ... These genes are all found in humans and have conserved areas with FAM149A. FAM149A has a conserved domain of unknown function ( ... Family with sequence similarity 149, member A is a protein that in humans is encoded by the FAM149A gene (also known as MSTP119 ... Only the dog contains what is considered as an Evolutionary Conserved Region (ECR). Based on the graphs on the right, the ...
*  Histone variants
H3 variants are highly sequence conserved differing only by a few amino acids. Histone H3.3 has been found to play an important ... The reason for a lack of sequence variants remains unclear. Trypanosoma are known to have a variant of H4 named H4.V. In ... H2A.X is the most common H2A variant, with the defining sequence motif 'SQ(E/D)Φ' (where Φ-represents a hydrophobic residue, ... Notable features of H2A.Z include a sequence motif 'DEELD,' a one amino acid insertion in L1-loop, and a one amino acid ...
*  Histone Database
Baxevanis AD, Landsman D (1996). "Histone Sequence Database: a compilation of highly-conserved nucleoprotein sequences". ... Makalowska I, Ferlanti ES, Baxevanis AD, Landsman D (1999). "Histone Sequence Database: sequences, structures, post- ... on-demand generation of multiple sequence alignments with feature annotations; classification of histone-like sequences and ... The core of the database is a manually curated set of histone sequences grouped into 30 different variant subsets with variant- ...