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*  Chemical biology
Bioorganic & Medicinal Chemistry - The Tetrahedron Journal for Research at the Interface of Chemistry and Biology ChemBioChem ... This technique allows for access to much larger proteins, as only the N-terminal portion of the resulting protein has to be ... "Solution structure of a de novo protein from a designed combinatorial library". Proc. Natl. Acad. Sci. USA. 100 (23): 13270-3. ... Chemical biology has scientific, historical and philosophical roots in medicinal chemistry, supramolecular chemistry, ...
*  Shimadzu Corp.
Swartz, Michael E. (2000-02-18). Analytical Techniques in Combinatorial Chemistry. CRC Press. pp. 278-279. ISBN 9780203909966. ... In 2002, Koichi Tanaka, a longstanding employee, won the Nobel Prize in Chemistry for developing a method of mass spectrometric ... Japan portal Electronics portal Analytical chemistry portal Companies portal List of companies of Japan List of scientific ...
*  Combinatorial chemistry
Materials science has applied the techniques of combinatorial chemistry to the discovery of new materials. This work was ... formerly Journal of Combinatorial Chemistry) Combinatorial Chemistry Review Molecular Diversity Combinatorial Chemistry and ... The methods used in combinatorial chemistry are applied outside chemistry, too. Synthesis of molecules in a combinatorial ... "The concealed side of the history of combinatorial chemistry" IUPAC's "Glossary of Terms Used in Combinatorial Chemistry" ACS ...
*  Prous Science
These techniques are complemented by laboratory methods from combinatorial chemistry, molecular biology and functional genomics ... statistical analysis and chemoinformatic techniques, a recent and innovative international concept registered under the name " ...
*  Systematic evolution of ligands by exponential enrichment
... is a combinatorial chemistry technique in molecular biology for producing oligonucleotides of either single-stranded DNA or RNA ... The technique has been used to evolve aptamers of extremely high binding affinity to a variety of target ligands, including ... Clinical uses of the technique are suggested by aptamers that bind tumor markers,, GFP-related fluorophores, and a VEGF-binding ... Carmi, Nir; Shultz, Lisa A.; Breaker, Ronald R. (Dec 1996). "In vitro selection of self-cleaving DNAs". Chemistry & Biology. 3 ...
*  Yvonne Connolly Martin
... she developed combinatorial chemistry and molecular graphics techniques and was involved in the development of software ... She was the only woman to be a chemistry/zoology major in her year. From 1958 to 1960 she worked as a pharmacology assistant at ... Editorially, she has worked on Perspectives in Drug Design and Discovery, QSAR: Annual Reports in Computational Chemistry, ... She has also significantly contributed to the development of compound collections and combinatorial libraries which ...
*  The Billion-Dollar Molecule
... companies to adopt an explicit strategy of rational drug design as opposed to techniques based on combinatorial chemistry. This ...
*  Dynamic combinatorial chemistry
Several analytical techniques have been applied to the analysis of protein-directed DCL. These include HPLC, mass spectrometry ... Protein-directed dynamic combinatorial chemistry. In Dynamic combinatorial chemistry: in drug discovery, bioinorganic chemistry ... Center for Dynamic Combinatorial Chemistry[citation needed] University of Cambridge: Dynamic Combinatorial Chemistry. ... Dynamic combinatorial chemistry (DCC; also known as dynamic covalent chemistry) is a method to the generation of new molecules ...
*  Molecule editor
A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry J. ... Molecular structure input on the web The Chemical Structure Editor: Bridging Chemistry and Cheminformatics Basic primitives for ...
*  Smiles arbitrary target specification
A Powerful New Technique for Identifying Privileged Molecular Fragments with Useful Applications in Combinatorial Chemistry J. ... RECAP (Retrosynthetic Combinatorial Analysis Procedure) uses SMARTS to define bond types. RECAP is a molecule editor which ... 54, 255-271 Lewell, X.Q.; Judd, D.B; Watson, S.P.; Hann, M.M. (1998) RECAP-Retrosynthetic Combinatorial Analysis Procedure: ...
*  Medicinal chemistry
... or from historic chemical compound collections or libraries created through combinatorial chemistry. While a number of ... approaches toward the identification and development of hits exist, the most successful techniques are based on chemical and ... Medicinal chemistry and pharmaceutical chemistry are disciplines at the intersection of chemistry, especially synthetic organic ... Medicinal chemistry is by nature an interdisciplinary science, and practitioners have a strong background in organic chemistry ...
*  Scavenger resin
Used primarily in the synthesis of medicinal drugs, solution-phase combinatorial chemistry allows for the creation of large ... Reaction may be monitored: The purification process is controlled Traditional purity techniques may be employed Can be used in ... Carlisle, Steven J. , Marsh, Andrew, Smith, S.C. (2001). "High-loading scavenger resins for combinatorial chemistry". ... Employment of scavenger resins has become increasingly popular in solution-phase combinatorial chemistry. ...
*  Christopher J. Schofield
... protein-directed dynamic combinatorial chemistry and organic synthesis/medicinal chemistry. Most clinically used antibiotics ... Techniques involved in this interdisciplinary research include proteomics, X-ray crystallography, nuclear magnetic resonance ( ... In 1998, he became professor of Chemistry, and in 2011 he was appointed the Head of Organic Chemistry at the Department of ... Chris Schofield is a professor of organic chemistry at the University of Oxford, Department of Chemistry and a Fellow of ...
*  Micellar electrokinetic chromatography
The advent of combinatorial chemistry has enabled medicinal chemists to synthesize and identify large numbers of potential ... Micellar electrokinetic chromatography (MEKC), is a chromatography technique, used in analytical chemistry. It is a ... Simms, P.J.; Jeffries, C.T.; Huang, Y.; Zhang, L.; Arrhenius, T.; Nadzan, A.M. (2001). "Analysis of Combinatorial Chemistry ... In MEKC, however, techniques must be used to extend the elution range to separate strongly retained analytes. Elution ranges ...
*  DNA-encoded chemical library
DEL is used in medicinal chemistry to bridge the fields of combinatorial chemistry and molecular biology. The aim of DEL ... The technique enables the mass creation and interrogation of libraries via affinity selection, typically on an immobilized ... Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution". PLoS Biol. 2 (7): E174. doi:10.1371/ ... In order to apply combinatorial chemistry for the synthesis of DNA-encoded chemical libraries, a Split-&-Pool approach was ...
*  Stuart Schreiber
Cope Award and the Wolf Prize in Chemistry. ACS Award in Pure Chemistry (1989) "For pioneering investigations into the ... DOS pathways and new techniques for small-molecule screening provided many new, potentially disruptive insights into biology. ... combinatorial synthesis and the so-called Build/Couple/Pair strategy of modular chemical synthesis. ... "For outstanding achievement in creative chemistry." Eli Lilly Award in Biological Chemistry, ACS (1993). "For fundamental ...
*  University of Edinburgh School of Chemistry
... the application of high throughput and combinatorial approaches and biophysical chemistry, which focuses on the development and ... polymer microarray technologies and technique development for materials and nanomaterials analysis. RAE 2008: chemistry results ... The teaching of Chemistry at Edinburgh began in 1713 when James Crawford was appointed to the Chair of Physics and Chemistry. ... The Materials Chemistry group is one of the largest materials chemistry groups in the UK. Areas of strength include the design ...
*  Drug discovery
Protein-directed dynamic combinatorial chemistry". In Miller BL. Dynamic combinatorial chemistry: in drug discovery, ... Nuclear magnetic resonance spectroscopy is the primary technique for determining chemical structures of natural products. NMR ... selection of different binders from the same uridine-based dynamic combinatorial library". Journal of Combinatorial Chemistry. ... Despite the rise of combinatorial chemistry as an integral part of lead discovery process, natural products still play a major ...
*  Discrete mathematics
... chemistry). Operations research provides techniques for solving practical problems in engineering, business, and other fields ... Discrete geometry and combinatorial geometry are about combinatorial properties of discrete collections of geometrical objects ... Operations research techniques include linear programming and other areas of optimization, queuing theory, scheduling theory, ... ISBN 978-0-13-045803-2. Kenneth H. Rosen; John G. Michaels (2000). Hand Book of Discrete and Combinatorial Mathematics. CRC ...
*  Pesticide research
"Combinatorial chemistry in the agrosciences". Bioorganic & Medicinal Chemistry. 17 (12): 4035. doi:10.1016/j.bmc.2009.03.027. ... Techniques such as fragment-based design, virtual screening and genome sequencing have helped generate drug leads. Published ... The sources of new molecules employ natural products, competitors, universities, chemical vendors, combinatorial chemistry ... "Screening technique uncovers five new plant activator compounds". Phys.org. Retrieved 2014-02-11. Yoshiteru Noutoshia, Masateru ...
*  Polyanhydrides
Journal of Combinatorial Chemistry, 7, 921-928, 2005. B.M. Vogel and S.K. Mallapragada, "The Synthesis of Polyanhydrides", in ... "Polyanhydride Synthesis Techniques." Wyatt Technology Corp. http://www.lightscattering.com/literature/polyanhydride.pdf Tamada ... These classes are determined by examining their R groups (the chemistry of the molecule between the anhydride bonds). Aliphatic ...
*  Fluorescence polarization immunoassay
Jameson, David (2003). "Fluorescence Polarization: Past, Present and Future". Combinatorial Chemistry & High Throughput ... Despite originating as a method for direct interaction studies, the technique has been adopted by high-throughput screening ( ... Eremin, SA (2003). "Fluorescence polarization immunoassays for pesticides". Combinatorial Chemistry & High Throughput Screening ... Combinatorial Chemistry & High Throughput Screening. 2: 177-190 - via ResearchGate. Smith, David (2008). "Fluorescence ...
*  Host-guest chemistry
Nuclear magnetic resonance (NMR) is one of the most powerful spectroscopic techniques in analytical chemistry. It is an ... and by doing so hope to gain further insight into the combinatorial outcome of these many, small, non-covalent forces that are ... In supramolecular chemistry, host-guest chemistry describes complexes that are composed of two or more molecules or ions that ... limits the accuracy of the technique. Raman spectroscopy is a spectroscopic technique used in the study of molecules which ...
*  Theoretical chemistry
Physical chemistry and chemical physics: Chemistry investigated via physical methods like laser techniques, scanning tunneling ... Examples are molecular docking, protein-protein docking, drug design, combinatorial chemistry. The fitting of shape and ... Theoretical chemistry is a branch of chemistry, which develops theoretical generalizations that are part of the theoretical ... Theoretical chemistry unites principles and concepts common to all branches of chemistry. Within the framework of theoretical ...
*  Structure-activity relationship
Combinatorial chemistry Congener Conformation activity relationship Quantitative structure-activity relationship Sims, Gerald; ... Medicinal chemists use the techniques of chemical synthesis to insert new chemical groups into the biomedical compound and test ... Sommers (1986). "Biodegradation of pyridine derivatives in soil suspensions". Environmental Toxicology and Chemistry. 5: 503- ...
*  Universal Decimal Classification
Preparative and experimental chemistry 543 Analytical chemistry 544 Physical chemistry 546 Inorganic chemistry 547 Organic ... Memoirs 82.02/.09 Special auxiliary subdivision for theory, study and technique of literature 82.02 Literary schools, trends ... Analysis 519.1 Combinatorial analysis. Graph theory 519.2 Probability. Mathematical statistics 519.6 Computational mathematics ... Solid state physics 539 Physical nature of matter 54 Chemistry. Crystallography. Mineralogy 542 Practical laboratory chemistry ...
*  CombiMatrix
The CombiMatrix microarray ("CombiMatrix" refers to combinatorial chemistry on a matrix array) was born and received US patents ... CombiMatrix performs genetic testing utilizing a variety of advanced cytogenomic techniques, including chromosomal microarray ...