Enhanced deposition of predominantly type I collagen in myocardial disease. J Mol Cell Cardiol. 1990;22:1157-1165 Table 11-2 in ...
Alpha 1 subunit of type VI collagen is the encoded protein. In terms of the diagnosis of Ullrich congenital muscular dystrophy ... via ScienceDirect (Subscription may be required or content may be available in libraries.) "COL6A1 collagen type VI alpha 1 [ ... GeneReviews/NCBI/NIH/UW entry on Collagen Type VI-Related Disorders O. Ullrich: Kongenitale, atonisch-sklerotische ... This sub-type of muscular dystrophy is autosomal recessive in nature. COL6A1 plays an important part in maintaining the human ...
The COL11A2 gene is responsible for providing instructions on making one component of the type XI collagen. Type XI collagen is ... which codes for the α2 strand of collagen type XI. It is a collagenopathy, types II and XI disorder. It causes facial ... The mutation of COL11A2 in Weissenbacher-Zweymüller syndrome disrupts the assembly of the type XI collagen molecules. The ... Collagen is found in bone. It is also found in cartilage that makes up most of the skeleton during early development. ...
Plenz GA, Deng MC, Robenek H, Völker W (2003). "Vascular collagens: spotlight on the role of type VIII collagen in ... The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen ... 1993). "Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI". Exp ... 1996). "Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 ...
... primarily a collagen-type protein. 1.3% of the slime's dry weight consists of sugars, mainly galactosamine. The slime also ... Two different types of blood cells (or haemocytes) circulate in the fluid: amoebocytes and nephrocytes. The amoebocytes ... The best-known is the type genus Peripatus, which was described as early as 1825 and which, in English-speaking countries, ... Beneath this lies a thick layer of connective tissue, which is composed primarily of collagen fibres aligned either parallel or ...
Plenz GA, Deng MC, Robenek H, Völker W (2003). "Vascular collagens: spotlight on the role of type VIII collagen in ... integrin upon release from keratinocytes migrating on type I collagen". J. Biol. Chem. 276 (31): 29368-74. doi:10.1074/jbc. ... They are found on a wide variety of cell types including, T cells (the NKT cells), NK cells, fibroblasts and platelets. ... Expression of CD49b in conjunction with LAG-3 has been used to identify type 1 regulatory (Tr1) cells. DX5 is a monoclonal ...
Cleaves type IV collagen at Ala73-Gln in alpha1(IV) and at Gly7-Leu in alpha2(IV) This endopeptidase is present in the venom of ... "Identification of the cleavave sites by a hemorrhagic metalloproteinase in type IV collagen". Matrix. 10 (2): 91-97. doi: ... 10.1016/s0934-8832(11)80175-7. PMID 2374521. Atrolysin E at the US National Library of Medicine Medical Subject Headings (MeSH ...
... within the human COL7A1 gene encoding the protein type VII collagen (collagen VII). DEB-causing mutations can be either ... Type VII collagen mutations and phenotype-genotype correlations in the dystrophic subtypes". Journal of Medical Genetics. 44 (3 ... There are 54 known keratin genes-of which 28 belong to the type I intermediate filament genes and 26 to type II-which work as ... The first two types tended to die in infancy and the last in early adulthood. An estimated 20 per million live births are ...
It has been reported that biglycan interacts more strongly with collagen type II than collagen type I. Biglycan has been ... Pogány G, Hernandez DJ, Vogel KG (August 1994). "The in vitro interaction of proteoglycans with type I collagen is modulated by ... "Binding of the proteoglycan decorin to collagen type VI". J. Biol. Chem. 267 (8): 5250-6. PMID 1544908. Bowe MA, Mendis DB, ... "Interaction of biglycan with type I collagen". J. Biol. Chem. 270 (6): 2776-83. doi:10.1074/jbc.270.6.2776. PMID 7852349. ...
This involved a mutation of the protein Collagen, type X, alpha 1, encoded by the COL10A1 gene. In humans a similar mutation ( ... December 2000). "Abnormal growth plate function in pigs carrying a dominant mutation in type X collagen". Mamm. Genome. 11 (12 ... Retrieved 2007-11-28. Kitoh H, Kitakoji T, Tsuchiya H, Katoh M, Ishiguro N (2007). "Distraction osteogenesis of the lower ...
... and XI. Type II and type XI collagens compose the fibrils present in cartilage. These can be distinguished from collagens ... Among the many types of collagens, only the fibrillar and the basement membrane (type IV) collagens have been found in the ... coding for collagen type IV which is a diagnostic feature of the basal lamina It has also been found that 29 types of collagen ... Different types of collagen have been found in all multicellular organisms, including sponges. It has been found that sponges ...
"Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner". Stem Cell Research & ... including collagen and glycosaminoglycans. The process is initiated when immune cells such as macrophages release soluble ... 135 (11): 2873-6. doi:10.1038/jid.2015.252. PMC 4640976 . PMID 26134944. Leask A, Abraham DJ (2004). "TGF-beta signaling and ...
... or assembly of type II or type XI collagen. Defective collagen molecules or reduced amounts of collagen affect the development ... These genes are involved in the production of type II and type XI collagen. Collagens are complex molecules that provide ... specifically collagen. Stickler syndrome is a subtype of collagenopathy, types II and XI. Stickler syndrome is characterized by ... A metabolic defect concerning the hyaluronic acid and the collagen of the 2-d type is assumed to be the cause of this syndrome ...
The protein made by the COL11A2 gene is involved in the production of type XI collagen. This type of collagen is important for ... A recessive pattern of inheritance makes OSMED unique among the type II and type XI collagenopathies. The distinctive ... Mutations in the COL11A2 gene lead to a loss of function of this type of collagen, resulting in the signs and symptoms of OSMED ... Otospondylomegaepiphyseal dysplasia is a subtype of collagenopathy, types II and XI. Mutations in the COL11A2 gene cause ...
It binds to the same site on the collagen type I molecule as lumican. It also inhibits fibrillogenesis of collagen type I and ... "Structural requirements for fibromodulin binding to collagen and the control of type I collagen fibrillogenesis--critical roles ... Kalamajski S, Oldberg A (2007). "Fibromodulin binds collagen type I via Glu-353 and Lys-355 in leucine-rich repeat 11". J Biol ... Kalamajski S, Oldberg A (Sep 2007). "Fibromodulin binds collagen type I via Glu-353 and Lys-355 in leucine-rich repeat 11". The ...
2006). "Overexpression of HMGA2-LPP fusion transcripts promotes expression of the alpha 2 type XI collagen gene". Biochem. ... 11 (1): 117-29. doi:10.1091/mbc.11.1.117. PMC 14761 . PMID 10637295. Rogalla P, Lemke I, Kazmierczak B, Bullerdiek J (2001). " ... 2001). "Human LPP gene is fused to MLL in a secondary acute leukemia with a t(3;11) (q28;q23)". Genes Chromosomes Cancer. 31 (4 ...
Research into synthetic collagen is ongoing; as of 2011, partial success has been achieved in replicating collagen's structure ... Instant types can be added to the food as they are; others need to be soaked in water beforehand. Gelatin is a mixture of ... Probably best known as a gelling agent in cooking, different types and grades of gelatin are used in a wide range of food and ... "Type A & B Process Definition". Vyse Gelatin Company. 26 October 2009. Archived from the original on 1 March 2015. Retrieved 16 ...
The ISneck domain is a type of neck domain. There are two types of ISneck domain. This first is an ISneck which is interrupted ... Nummelin H, Merckel MC, Leo JC, Lankinen H, Skurnik M, Goldman A (2004). "The Yersinia adhesin YadA collagen-binding domain ... There are several types of head domain. Each domain helps the head to bind to a different component of the extracellular matrix ... There are two types of stalk domain: the FGG domain and the right-handed stalk domain. Structure: The structure of this protein ...
Aug 2001). "Mammary-type myofibroblastoma of soft tissue: a tumor closely related to spindle cell lipoma". Am J Surg Pathol. 25 ... consist of bland spindle cells arranged in fascicles with interspersed thick bundles of collagen. They typically stain with ... In extra-mammary sites the tumour is known as a mammary-type myofibroblastoma, and may immunohistochemically and ...
Normal, intact tendon is composed mainly of type I collagen, and type III collagen increases after injury. Another study has ... Type I collagen is the primary collagen in tendons. Nonbulbar dermal sheath cells will be replicated, and then reintroduced ... This report further indicates that a decrease in type I procollagen (and increase in type III collagen and periostin) ... into the tendon to decrease the production of type 3 collagen and switch to type-1. As of November 2013, researchers at the ...
Relation of alleles of the collagen type 11 gene to bone density and the risk of osteoporotic fractures in postmenopausal women ... 1991;324:1305-11. Walter HJ, Hofman A, Vaughan RD, Wynder E. Modification of risk factors for coronary heart disease. Five-year ...
... collagen type I, and that it interacts with the "d" and "e" bands of fibrils of this collagen. Decorin appears to influence ... This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. ... Decorin has been shown to interact with: Collagen type I Epidermal growth factor receptor and TGF beta 1, TLR2, and TLR4. ... "Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen ...
... and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene". The EMBO Journal. 17 (19 ... 11 (3): 422-35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166. Murakami A, Ishida S, Thurlow J, Revest JM, Dickson C (Aug ... 20 (11): 2887. doi:10.1093/nar/20.11.2887. PMC 336939 . PMID 1614875. Lefebvre V, Li P, de Crombrugghe B (Oct 1998). "A new ... 10 (11): 1788-95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl ...
Leitinger B, Kwan AP (2006). "The discoidin domain receptor DDR2 is a receptor for type X collagen". Matrix Biol. 25 (6): 355- ... "Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer ... "Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen". J. Biol. Chem. 277 (21): ... "Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen". J. Biol. Chem. 277 (21): ...
The main substrates of the gelatinases are type IV collagen and gelatin, and these enzymes are distinguished by the presence of ... All six membrane-type MMPs (#14, No. 15, #16, No. 17, #24, and #25) have a furin cleavage site in the pro-peptide, which is a ... These collagens are the major components of bone, cartilage and dentin, and MMPs are the only known mammalian enzymes capable ... 14 has also been shown to cleave fibrillar collagen, and there is evidence that No. 2 is capable of collagenolysis. In MeSH, ...
Several types of catenins work with N-cadherins to play an important role in learning and memory (For full article, see ... Spivey KA, Chung I, Banyard J, Adini I, Feldman HA, Zetter BR (October 2011). "A role for collagen XXIII in cancer cell ... For instance, higher levels of collagen XXIII have been associated with higher levels of catenins in cells. These heightened ... levels of collagen helped facilitate adhesions and anchorage-independent cell growth and provided evidence of collagen XXIII's ...