... is a type of collagen which can be cleaved to form endostatin. The endostatin is from the c terminus end of ... This type of mutation particularly affects only one isoform of type XVIII collagen - the short isoform type, while the medium ... which codes for production of type XVIII collagen. It is speculated that the mutation of type XVIII collagen that occurs in ... When type XVIII collagen is mutated at the COL18A1 gene, exon 2 in the sequence is skipped, which results in production of an ...

Collagen, type I, alpha 1 (COL1A1) Collagen, type II, alpha 1 (COL2A1) Collagen, type III, alpha 1 (COL3A1) Collagen, type V, ... Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. ... collagen types VI, VII, XII and XIV; and other extracellular proteins. Although the majority of VWA-containing proteins are ... "Type A modules: interacting domains found in several non-fibrillar collagens and in other extracellular matrix proteins". ...

Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions". J. ... Colombatti A, Bonaldo P, Doliana R (1993). "Type A modules: interacting domains found in several non-fibrillar collagens and in ... collagen types VI, VII, XII and XIV; and other extracellular proteins. Although the majority of vWA-containing proteins are ... This type A domain is the prototype for a protein superfamily (InterPro: IPR036465; see also Pfam clan). The vWA domain is ...

Collagens α1(XIII), α1(XXIII) and α1(XXV) display three collagenous domains (Col 1, Col 2, and Col 3) and four non-collagenous ... "Entrez Gene: COL23A1 collagen, type XXIII, alpha 1". Banyard J, Bao L, Zetter BR (June 2003). "Type XXIII collagen, a new ... The molecule of collagen XXIII can be found either in membrane-bond form or in shed form. Type XXIII collagen is expressed in ... Collagen XXIII is a type II transmembrane protein and the fourth in the subfamily of non-fibrillar transmembranous collagens. ...

"Association of Collagen Type I Alpha 1 Gene Polymorphism With Inguinal Hernia - PubMed". Hernia: The Journal of Hernias and ... Different types of inguinal hernias. Inguinal fossae There are two types of inguinal hernia, direct and indirect, which are ... "Hernia: Treatment, Types, Symptoms (Pain) & Surgery". "UOTW #16 - Ultrasound of the Week". Ultrasound of the Week. 2 September ... Repair, however, is generally recommended in females due to the higher rate of femoral hernias (also a type of groin hernia) ...

... s (collagen-containing C-type lectins) are a part of the innate immune system. They form a family of collagenous Ca2+- ... Monomeric subunit consists of four parts: a cysteine-rich domain at the N-terminus a collagen-like domain a coiled-coil neck ... McNeely, T B; J D Coonrod (July 1994). "Aggregation and opsonization of type A but not type B Hemophilus influenzae by ... Nine types of collectins have been defined: MBL = mannan-binding lectin (mannose-binding lectin) SP-A = surfactant protein A SP ...

"Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: Pain ... iv: 139-159. W. N. Haworth; W. H. G. Lake; S. Peat (1939). "The configuration of glucosamine (chitosamine)". Journal of the ... "Therapeutic Efficacy and Safety of Undenatured Type II Collagen Singly or in Combination with Glucosamine and Chondroitin in ... "The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes ...

... characterize the α1 chain of type V collagen and was also key in the first demonstration that mutations in a type V collagen ... on collagen V genes and on the biosynthesis of type V collagen and on the molecular mechanisms whereby mutations in type V ... The Greenspan lab was also the first to clone and characterize the α3 chain of type V collagen and showed the α3(V) chain to be ... Huang, G., Ge, G., Izzi, V., & Greenspan, D. S. (2017). α3(V) chains of type V collagen regulate breast tumour growth via ...

In type I the collagen's structure itself is normal, it is just its quantity that is low.: 1516 Types II, III and IV are ... As in type I, some further split type IV into types IV-A and IV-B, defined again by the absence (IV-A) or presence (IV-B) of ... There are four clinically defined types: type I, the least severe; type IV, moderately severe; type III, severe and ... type I was nearly six times more common than type III and nearly four times more common than type IV. Most people with OI ...

... collagen, type I, alpha 1 (17q21.33) LUC7L3: LUC7 like 3 pre-mRNA splicing factor (17q21.33) NOG: Noggin protein (17q22) ... syndrome Maturity onset diabetes of the young type 5 Miller-Dieker syndrome Multiple synostoses syndrome Neurofibromatosis type ... Solute carrier family 4, member 1 (17q21.31) CBX1: chromobox homolog 1 (17q21.32) COL1A1: ... verruciformis Frontotemporal dementia and parkinsonism linked to chromosome 17 Galactosemia Glycogen storage disease type II ( ...

"Mutations in collagen, type XVII, alpha 1 (COL17A1) cause epithelial recurrent erosion dystrophy (ERED)". Hum. Mutat. 36 (4): ... With the eye generally profusely watering, the type of tears being produced have little adhesive property. Water or saline eye ... Where episodes frequently occur, or there is an underlying disorder, one medical, or three types of surgical curative ... 123 (4): 709-22. doi:10.1016/j.ophtha.2015.12.008. PMID 26786512. Lin BR, Le DJ, Chen Y, Wang Q, Chung DD, Frausto RF, ...

... and the resultant synthesis of type 2 collagen, the same native collagen found in the undamaged cartilage tissue. These ... Gomoll AH, Probst C, Farr J, Cole BJ, Minas T (November 2009). "Use of a type I/III bilayer collagen membrane decreases ... Periosteum covered versus type I/III collagen covered". Knee. 13 (3): 203-10. doi:10.1016/j.knee.2006.02.011. ISSN 0968-0160. ... "Autologous chondrocyte implantation in chondral defects of the knee with a type I/III collagen membrane: A prospective study ...

... domains at the C-termini of the alpha-1 and alpha-3 chains of type VI and type VII collagens; tissue factor pathway inhibitor ... "Anisotropic behaviour of the C-terminal Kunitz-type domain of the alpha3 chain of human type VI collagen at atomic resolution ( ... The type example for this family is BPTI (or basic protease inhibitor), but the family includes numerous other members, such as ... Examples of Kunitz-type protease inhibitors are aprotinin (bovine pancreatic trypsin inhibitor, BPTI), Alzheimer's amyloid ...

Type I domain (FN1) is approximately 40 residues in length. Four conserved cysteines are involved in disulfide bonds. The 3D ... Fibronectin is a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and ... Fibronectin, type I repeats are one of the three repeats found in the fibronectin protein. ... F12; FN1; HGFAC; PLAT; Campbell ID, Baron M, Norman D, Willis A (1990). "Structure of the fibronectin type 1 module". Nature. ...

... a type of glycopolymer. Nematode cyst walls are composed of chitin reinforced by collagen. The cyst wall is composed of four ... Various types of branchiopods can produce diapause cysts. This is an adaptation to living in ephemeral pools in fresh or ... As an example Rhodospirillium centenum can change the number of cell per cyst, usually ranging from four to ten cells per cyst ... 4 45R-59R "Division of Environmental Health". www.idph.state.il.us. Retrieved 2019-11-12. Lewis, F.J. Von M. "Survival of ...

... leads to defective production of the collagen, type III, alpha 1 protein and causes skin fragility as well as weakness of the ... Four treatment modalities have been reported in the treatment of vertebral artery dissection. The two main treatments involve ... Vertebral artery dissection is one of the two types of cervical artery dissection. The other type, carotid artery dissection, ... The vertebral artery supplies the part of the brain that lies in the posterior fossa of the skull, and this type of stroke is ...

... type II collagen) gene. Povinelli was born in Elyria, Ohio, and is the youngest of four children. His parents and siblings are ... "Dominant mutations in the type II collagen gene, COL2A1, produce spondyloepimetaphyseal dysplasia, Strudwick type". Nature ...

... ropey collagen, and spindle cells in a myxoid (i.e. background connective tissue that stains blue or purple rather than the red ... Further complicating the issue, early studies on MFB classified it as one of various types of spindle cell tumors that, except ... Mammary-type myofibroblastoma (MFB), also named mammary and extramammary myofibroblastoma, was first termed myofibrolastoma of ... The World Health Organization in 2020 classified mammary type myofibroblastoma tumors and myofibroblastoma tumors (i.e. ...

The structure of SP-A2 monomers consists of four domains: an N-terminal, a collagen-like domain, a neck region, and a ... The protein encoded by this gene (SP-A2) is primarily synthesized in lung alveolar type II cells, as part of a complex of ... The structure of SFTPA2 consists of four coding exons (I-IV), and several 5'UTR untranslated exons (A, B, B', C, C', D, D'). ... SP-A2 is a member of a subfamily of C-type lectins called collectins. Together with (surfactant protein A1 ) SP-A1, they are ...

The structure of SP-A1 monomers consists of four domains: an N-terminal, a collagen-like domain, a neck region, and a ... SP-A1 is primarily synthesised in type II alveolar cells in the lung, as part of a complex of lipids and proteins known as ... The structure of SFTPA1 consists of four coding exons (I-IV), and several 5'UTR untranslated exons (A, B, B', C, C', D, D'). ... SP-A1 is a member of a subfamily of C-type lectins called collectins. Together with SP-A2, they are the most abundant proteins ...

2004). "TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis". ... 24 (4): 1758-68. doi:10.1128/MCB.24.4.1758-1768.2004. PMC 344171. PMID 14749390. Gerhard DS, Wagner L, Feingold EA, et al. ( ...

Type XVII collagen (Col17)-knockout (KO) mice that simulate junctional EB and recurrent skin injuries received 5.0 × 10^4 human ... Similarly, four of the five mice in the Muse group showed the deposition of human COL17 in association with Muse cell-derived ... Human adipose tissue-derived Muse-rich cells significantly accelerate wound healing in skin ulcers of a mouse type 1 diabetes ... Muse cells from different sources are capable of in vitro differentiation into various cell types. Human dermal fibroblast- ...

Cultures from tendinopathic tendons contain an increased production of type III collagen. Longitudinal sonogram of the lateral ... "Tenocytes from ruptured and tendinopathic achilles tendons produce greater quantities of type III collagen than tenocytes from ... a shift from large to small diameter collagen fibrils, buckling of the collagen fascicles in the tendon extracellular matrix, ... Other types of pain medication, like paracetamol, may be just as useful. Steroid injections have not been shown to have long ...

DEB is caused by genetic defects (or mutations) within the human COL7A1 gene encoding the protein type VII collagen (collagen ... There are four main types: epidermolysis bullosa simplex (EBS), dystrophic epidermolysis bullosa (DEB), junctional ... Type VII collagen mutations and phenotype-genotype correlations in the dystrophic subtypes". Journal of Medical Genetics. 44 (3 ... Loss or diminished function of type VII collagen leads to weakness in the structural architecture of the dermal-epidermal ...

... type II collagen) but not fibroblasts. Implanted into defects created in the articular cartilage of rats, human iChon cells ... Reprogramming in vivo, by transitory induction of the four factors Oct4, Sox2, Klf4 and c-Myc in mice, confers totipotency ... causes the formation of new muscle cell types as well as other cell types such as precursors to fat, bone, and nervous system ... Some types of mature, specialized adult cells can naturally revert to stem cells. For example, "chief" cells express the stem ...

The collagen of the sclera is continuous with the cornea. From outer to innermost, the four layers of the sclera are: episclera ... stroma lamina fusca endothelium The sclera is opaque due to the irregularity of the Type I collagen fibers, as opposed to the ... The thickness of the sclera varies from 1 mm at the posterior pole to 0.3 mm just behind the insertions of the four rectus ... In primitive fish, this ring consists of four plates, but the number is lower in many living ray-finned fishes, and much higher ...

Svensson L, Närlid I, Oldberg A (Mar 2000). "Fibromodulin and lumican bind to the same region on collagen type I fibrils". FEBS ... There are four N-linked sites within the leucine-rich repeat domain of the protein core that can be substituted with keratan ... This enables it bind to collagen molecules within a collagen fibril, thus helping keep adjacent fibrils apart. Lumican is a ... Li Y, Aoki T, Mori Y, Ahmad M, Miyamori H, Takino T, Sato H (Oct 2004). "Cleavage of lumican by membrane-type matrix ...

2006). "Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low ... In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the ... The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of ... The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a ...

"Entrez Gene: COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase". Human COLQ ... Type Ic)". Am. J. Hum. Genet. 63 (4): 967-75. doi:10.1086/302059. PMC 1377491. PMID 9758617. Ohno K, Brengman JM, Felice KJ, et ... This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each ... Ting AK, Siow NL, Kong LW, Tsim KW (2006). "Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast ...

There are four structural classifications of joints: fibrous joint - joined by dense regular connective tissue that is rich in ... collagen fibers cartilaginous joint - joined by cartilage. There are two types: primary cartilaginous joints composed of ... Types of articular surfaces include trochlear surfaces. Joints can also be classified based on their anatomy or on their ... Synovial joints can in turn be classified into six groups according to the type of movement they allow: plane joint, ball and ...