With type I collagen and possibly all fibrillar collagens, if not all collagens, each triple-helix associates into a right- ... The synthesis of collagen occurs inside and outside of the cell. The formation of collagen which results in fibrillary collagen ... Multiple collagen fibrils form into collagen fibers. Collagen may be attached to cell membranes via several types of protein, ... of the collagen in the human body is type I collagen. However, as of 2011, 28 types of human collagen have been identified, ...

Collagen, type I, alpha 1 Collagen, type II, alpha 1 Collagen, type III, alpha 1 Collagen, type IV, alpha 1 Collagen, type V, ... alpha 1 Collagen, type VI, alpha 1 Collagen, type VII, alpha 1 Collagen, type VIII, alpha 1 Collagen, type IX, alpha 1 Collagen ... collagen (type I, II, VI, X collagen fibrils) and proteoglycans. The ratio and the proportion of collagen play an important ... The targeted cells can process the α- chain peptides to form triple helix collagen, and replenish the collagen in the targeted ...

... is the gradual decrease of levels of collagen in the body. Collagen is the main structural protein found in the ... Various types of collagens have individual roles and structures. Most collagen belongs to types 1, 2, and 3. Collagen consists ... When collagen is lost in large amounts, it may cause wrinkles to emerge. Tobacco use can also result in slow collagen healing. ... The use of tobacco can cause damage to the skin's collagen layer. It can cause the skin around the lips to lose collagen when ...

... is a term previously used to describe systemic autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus ... ISBN 0-8027-0449-2. Collagen disease entry in the public domain NCI Dictionary of Cancer Terms This article incorporates public ... "collagen disease" was coined by Dr. Alvin F. Coburn in 1932, on his quest to discover streptococcal infection as the cause for ... but now is thought to be more appropriate for diseases associated with defects in collagen, which is a component of the ...

FACIT collagens include collagen types IX, XII, XIV, XIX, and XXI. Triple helix Collagen helix GO term: FACIT collagen[ ... FACIT collagen (Fibril Associated Collagens with Interrupted Triple helices) is a type of collagen and also a proteoglycan that ... Fibril-associated collagens with interrupted triple helices (FACIT collagens) are a subset of collagens that contribute to the ... FACIT collagens derive their name from their association and interaction with fibrillar collagens. Unlike fibrillar collagens, ...

Binds fibril-forming collagens, collagen of types I, II, III and X. A specific binding site in collagen II has been identified ... It preferentially binds collagens IV, VI and type XIII collagen, but also fibril-forming collagens. Specific binding sites in ... A ligand of Lair-1 receptor is type XVII transmembrane collagen, it binds type I and III collagen as well. Collagen binding ... It binds fibril-forming collagens and primarily type IV collagen, but also collagen of types I, VI, VIII. It is expressed ...

Collagen folded into a triple helix is known as tropocollagen. Collagen triple helices are often bundled into fibrils which ... The rise of the collagen helix (superhelix) is 2.9 Å (0.29 nm) per residue. The center of the collagen triple helix is very ... including type I collagen. In 1954, Ramachandran & Kartha (13, 14) advanced a structure for the collagen triple helix on the ... the collagen triple helix or type-2 helix is the main secondary structure of various types of fibrous collagen, ...

... (ColVI) is a type of collagen primarily associated with the extracellular matrix of skeletal muscle. ColVI ... Lampe AK, Flanigan KM, Bushby KM, Hicks D (August 9, 2012). "Collagen VI-Related Dystrophies". Collagen Type VI-Related ... Type VI collagen anchors endothelial basement membranes by interacting with type IV collagen. J. Biol. Chem. 272, 26522-26529. ... The absence of collagen VI impacted the structure and shape of the knee joint, but did not critically affect physicality of the ...

Collagen is denatured by heating in the presence of SDS prior to loading the gel. The collagen bands are visualized through CHP ... Collagen is the main component of the extracellular matrix (ECM). The collagen superfamily consists of 28 different types of ... The binding does not depend on a specific sequence or epitope on collagen, enabling CHPs to target denatured collagen chains of ... However, changes of collagen homeostasis are associated with numerous diseases and pathological conditions. Excessive collagen ...

Tight collagen helix The most common collagen is type I collagen which makes up 90% of all collagen. It is found in all dermal ... Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C- ... Collagen IV is the more common usage, as opposed to the older terminology of "type-IV collagen".[citation needed] Collagen IV ... show that the collagen hybridizing peptide probes can be used across species and collagen types (including type IV collagen), ...

Type I collagen Collagen, type III, alpha 1 Park KS, Park MJ, Cho ML, Kwok SK, Ju JH, Ko HJ, Park SH, Kim HY (2009). "Type II ... Type II collagen is organised into fibrils. This fibrillar network of collagen allows the cartilage to entrap the proteoglycan ... Collagen+type+II at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short ... Type II collagen is the basis for hyaline cartilage, including the articular cartilages at joint surfaces. It is formed by ...

Collagen-induced arthritis (CIA) is a condition induced in mice (or rats) to study rheumatoid arthritis. CIA is induced in mice ... Williams, RO (2004). "Collagen-induced arthritis as a model for rheumatoid arthritis". Tumor Necrosis Factor. pp. 207-16. doi: ... Arthritis in mice induced by a single immunisation with collagen v t e (CS1 errors: periodical ignored, Articles with short ... cite book}}: ,journal= ignored (help) Brand, DD; Latham, KA; Rosloniec, EF (2007). "Collagen-induced arthritis". Nat Protoc. 2 ...

... is the protein predicted to be encoded by COL27A1. It was first described by Dr. James M. Pace and his ... It is related to the fibrillar collagens: type II, type XI, and type XXIV. Current research suggests that it is made by ... v t e (Articles lacking sources from December 2009, All articles lacking sources, Collagens, All stub articles, Protein stubs) ...

... is a type of collagen which can be cleaved to form endostatin. The endostatin is from the c terminus end of ... which codes for production of type XVIII collagen. It is speculated that the mutation of type XVIII collagen that occurs in ... When type XVIII collagen is mutated at the COL18A1 gene, exon 2 in the sequence is skipped, which results in production of an ... The collagen XVIII is located within the basement membrane, and plays a major role in the integrity of the structure of the ...

April 2012). "Collagen induction therapy for the treatment of upper lip wrinkles". J Dermatolog Treat. 23 (2): 144-52. doi: ... Collagen induction therapy (CIT), also known as microneedling, dermarolling, or skin needling, is a cosmetic procedure that ... PRP is derived from the patient's own blood and may contain growth factors that increase collagen production. It can be applied ... Abuaf OK, Yildiz H, Baloglu H, Bilgili ME, Simsek HA, Dogan B (December 2016). "Histologic Evidence of New Collagen Formulation ...

Collagen Type II collagen Collagen, type I, alpha 1 Collagen, type I, alpha 2 Collagen, type III, alpha 1 "Collagen: What it is ... Type I collagen is the most abundant collagen of the human body, consisting of around 90% of the body's total collagen. It ... The cross-links result in the formation of very strong mature type I collagen fiber. See Collagen, type I, alpha 1#Clinical ... to make a molecule of type I pro-collagen. These triple-stranded, rope-like pro-collagen molecules must be processed by enzymes ...

... is a part of the family of collagen proteins consisting of Collagen I- Collagen XXVIII. Collagen proteins are ... Together, Collagen V and Collagen I acts as a dominant regulator of collagen fibrillogenesis. Type V Collagens interacts with ... Type V collagen is a part of the Extracellular Matrix (ECM). Collagen V is gene expression modulated by TGF-β. Type V collagen ... Type V Collagen is considered a regulatory fibril forming collagen. Collagen V is associated with the COL5A1 gene which is the ...

The collagen gel contraction assay is a type of wound contraction. It is performed using the dermal equivalent model, which ... consists of dermal fibroblasts seeded into a collagen gel. Macrophages restrain contraction of an in vitro wound healing model ...

Collagen alpha-2(IV) chain is a protein that in humans is encoded by the COL4A2 gene. This gene encodes one of the six subunits ... "Entrez Gene: COL4A2 collagen, type IV, alpha 2". Hinek A (1995). "Nature and the multiple functions of the 67-kD elastin-/ ... Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another ... Pöschl E, Pollner R, Kühn K (1988). "The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen ...

This gene encodes one of the chains for type I collagen, the fibrillar collagen found in most connective tissues. Mutations in ... Type-I collagen Collagen GRCh38: Ensembl release 89: ENSG00000164692 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of diseases of bone, cartilage, ... "Entrez Gene: COL1A2 collagen, type I, alpha 2". Byers PH, Wallis GA, Willing MC (1991). "Osteogenesis imperfecta: translation ...

The COL11A1 gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a ... collagen cDNA demonstrates that type XI belongs to the fibrillar class of collagens and reveals that the expression of the gene ... "Entrez Gene: COL11A1 collagen, type XI, alpha 1". GeneReviews/NCBI/NIH/UW entry on Stickler Syndrome Yoshioka H, Ramirez F ( ... Collagen alpha-1(XI) chain is a protein that in humans is encoded by the COL11A1 gene. ...

Collagen XVII is a transmembrane protein, like collagen XIII, XXIII and XXV. Collagen XVII is a structural component of ... The C-terminus of collagen XVII binds to laminin 5, and correct integration of laminin 5 into the matrix requires collagen XVII ... Mutations in the human collagen XVII gene, COL17A1, lead to the absence or structural alterations and mutations of collagen ... Collagen XVII is a homotrimer of three alpha1(XVII)-chains and a transmembrane protein in type II orientation. Each 180 kD a- ...

Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. ... This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. ... "Entrez Gene: COL9A3 collagen, type IX, alpha 3". GeneReviews/NCBI/NIH/UW entry on Multiple Epiphyseal Dysplasia, Dominant ... Collagen alpha-3(IX) chain is a protein that in humans is encoded by the COL9A3 gene. ...

Collagen alpha-1(XXI) chain is a protein that in humans is encoded by the COL21A1 gene. The protein is an extracellular matrix ... "COL21A1 collagen, type XXI, alpha 1". Entrez Gene: COL21A1. United States National Center for Biotechnology Information. Chou ... MY, Li HC (March 2002). "Genomic organization and characterization of the human type XXI collagen (COL21A1) gene". Genomics. 79 ...

Collagen XXIII shows structural homology with collagen XIII and collagen XXV . Apart from having the characteristic structure ... The molecule of collagen XXIII can be found either in membrane-bond form or in shed form. Type XXIII collagen is expressed in ... "Entrez Gene: COL23A1 collagen, type XXIII, alpha 1". Banyard J, Bao L, Zetter BR (June 2003). "Type XXIII collagen, a new ... Collagen XXIII is a type II transmembrane protein and the fourth in the subfamily of non-fibrillar transmembranous collagens. ...

This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major ... "Entrez Gene: COL8A1 collagen, type VIII, alpha 1". Shuttleworth CA (1998). "Type VIII collagen". Int. J. Biochem. Cell Biol. 29 ... Plenz GA, Deng MC, Robenek H, Völker W (2003). "Vascular collagens: spotlight on the role of type VIII collagen in ... The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the ...

Collagen alpha-1(VI) chain is a protein that in humans is encoded by the COL6A1 gene. The collagens are a superfamily of ... Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the ... "Entrez Gene: COL6A1 collagen, type VI, alpha 1". Bertini E, Pepe G (2002). "Collagen type VI and related disorders: Bethlem ... "Further characterization of the three polypeptide chains of bovine and human short-chain collagen (intima collagen)". Eur. J. ...

Collagen XIII belongs to the transmembranous subfamily of collagens, like collagen XVII, XXIII and XXV. GRCh38: Ensembl release ... Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha ... Latvanlehto A, Snellman A, Tu H, Pihlajaniemi T (2003). "Type XIII collagen and some other transmembrane collagens contain two ... Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain ...

This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with ... Changes of collagen XV can be known to lead to cancer-like behavior in tissues. The loss of collagen XV would no longer provide ... Type XV collagen is known to be a tumor suppressor that can be used to understand tumor cells environment. Type XV collagen ... "Epitope-defined monoclonal antibodies against multiplexin collagens demonstrate that type XV and XVIII collagens are expressed ...

Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have ... This gene encodes one of the three alpha chains of type IX collagen, a collagen component of hyaline cartilage. ... "Entrez Gene: COL9A1 collagen, type IX, alpha 1". GeneReviews/NCBI/NIH/UW entry on Multiple Epiphyseal Dysplasia, Dominant ... Collagen alpha-1(IX) chain is a protein that in humans is encoded by the COL9A1 gene. ...