The coatomer protein complex is made up of seven nonidentical protein subunits. These seven nonidentical protein subunits are ... The coatomer is a protein complex that coats membrane-bound transport vesicles. Two types of coatomers are known: COPI ( ... Coatomer+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Boehm, Markus; Bonifacino, Juan S. ( ... COP II is a coatomer that coats the vesicles transporting proteins from the ER to the golgi complex. This pathway is referred ...

The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds ... "Entrez Gene: COPE coatomer protein complex, subunit epsilon". Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, ... Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... Coatomer subunit epsilon is a protein that in humans is encoded by the COPE gene. ...

Coatomer subunit gamma is a protein that in humans is encoded by the COPG gene. It is one of seven proteins in the COPI ... "Entrez Gene: COPG coatomer protein complex, subunit gamma". Bermak, Jason C; Li Ming; Bullock Clayton; Weingarten Paul; Zhou ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ... "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell ...

Coatomer subunit alpha is a protein that in humans is encoded by the COPA gene. In eukaryotic cells, protein transport between ... "Entrez Gene: COPA coatomer protein complex, subunit alpha". Gerich B, Orci L, Tschochner H, Lottspeich F, Ravazzola M, Amherdt ... 1997). "Association of coatomer proteins with the beta-receptor for platelet-derived growth factor". Biochem. Biophys. Res. ... 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex". J. Cell ...

Coatomer subunit gamma-2 is a protein that in humans is encoded by the COPG2 gene. COPG2 has been shown to interact with ... "Entrez Gene: COPG2 coatomer protein complex, subunit gamma 2". Bermak JC, Li M, Bullock C, Weingarten P, Zhou QY (Feb 2002). " ... Waters MG, Serafini T, Rothman JE (1991). "'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ...

Coatomer subunit zeta-1 is a protein that in humans is encoded by the COPZ1 gene. COPZ1 has been shown to interact with COPG. ... "Entrez Gene: COPZ1 coatomer protein complex, subunit zeta 1". Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (November ... "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell ... Overview of all the structural information available in the PDB for UniProt: P61923 (Human Coatomer subunit zeta-1) at the PDBe ...

"The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon". J. Biol. Chem. 272 (46): 29200 ... Coatomer subunit beta is a protein that is encoded by the COPB2 gene in humans. The Golgi coatomer complex (see MIM 601924) ... "Entrez Gene: COPB2 coatomer protein complex, subunit beta 2 (beta prime)". Eugster A, Frigerio G, Dale M, Duden R (August 2000 ... "Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human ...

... is a coatomer, a protein complex that coats vesicles transporting proteins from the cis end of the Golgi complex back to ... 1994). "Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum". Cell. 79 (7): 1199-207. ... Luminal proteins: Proteins found in the lumen of the Golgi complex that need to be transported to the lumen of the ER contain ... 1996). "A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding". J Cell Biol. 135 (5 ...

Coatomer subunit beta is a protein that in humans is encoded by the COPB1 gene. COPI coatomer, a protein complex GRCh38: ... 1997). "Association of coatomer proteins with the beta-receptor for platelet-derived growth factor". Biochem. Biophys. Res. ... Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... Pavel J, Harter C, Wieland FT (1998). "Reversible dissociation of coatomer: Functional characterization of a β/δ-coat protein ...

Though PCTV does not require COPII coatomer proteins for budding from the ER, association with the coatomer is necessary for ... Without the fully functional sar1B protein, the COPll coatomer proteins engulf pre-chylomicrons exiting the ER but are unable ... Sar1B is a GTPase and one of the five proteins of the COPll coatomer. A mutation in the sar1B gene and subsequently the sar1B ... Before the PCTV leaves the ER, it is incorporated into a COPII coatomer of five proteins. The PCTV undergoes a similar ...

Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... 2000). "A New Paxillin-binding Protein, PAG3/Papα/KIAA0400, Bearing an ADP-Ribosylation Factor GTPase-activating Protein ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF ...

Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF ... ADP-ribosylation factor 4 is a protein that in humans is encoded by the ARF4 gene. ADP-ribosylation factor 4 (ARF4) is a member ... Shin OH, Ross AH, Mihai I, Exton JH (1999). "Identification of arfophilin, a target protein for GTP-bound class II ADP- ...

Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... Boman AL, Kuai J, Zhu X, Chen J, Kuriyama R, Kahn RA (1999). "Arf proteins bind to mitotic kinesin-like protein 1 (MKLP1) in a ... Boman AL, Kuai J, Zhu X, Chen J, Kuriyama R, Kahn RA (October 1999). "Arf proteins bind to mitotic kinesin-like protein 1 ( ... The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF ...

These vesicles have specific coat proteins (such as clathrin or coatomer) that are important for cargo selection and direction ... AP (adaptor protein) complexes are found in coated vesicles and clathrin-coated pits. AP complexes connect cargo proteins and ... Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to ... Touz MC, Kulakova L, Nash TE (July 2004). "Adaptor protein complex 1 mediates the transport of lysosomal proteins from a Golgi- ...

Orcl L, Palmer DJ, Amherdt M, Rothman JE (1993). "Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins ... ARF6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human ARF6 genome location and ... D'Souza-Schorey C, Boshans RL, McDonough M, Stahl PD, Van Aelst L (1997). "A role for POR1, a Rac1-interacting protein, in ARF6 ... ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety ...

Adaptins are distantly related to the other main type of vesicular transport proteins, the coatomer subunits, sharing between ... Protein pages needing a picture, Peripheral membrane proteins, Protein families). ... Adaptor protein (AP) complexes are found in coated vesicles and clathrin-coated pits. AP complexes connect cargo proteins and ... Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to ...

They are also common in membrane coat proteins known as coatomers, such as clathrin, and in regulatory proteins that form ... The protein-protein interaction capacity of alpha solenoid proteins also makes them well suited to function as regulatory ... extended protein-protein interaction surfaces or to form deep concave areas for binding globular proteins. Because they are ... "When protein folding is simplified to protein coiling: the continuum of solenoid protein structures". Trends in Biochemical ...

... a human gene that encodes the protein coatomer subunit epsilon COPE (film), a 2007 psychological thriller/horror independent ...

... a human gene that encodes the coatomer subunit alpha protein Controlling Profitability Analysis, Profitability Analysis (SAP) ...

Components of COPI (cop one) a coatomer, and TSET (T-set) a membrane trafficking complex have similar heterotetramers of the AP ... In the AP complexes, there are two large proteins (~100 kD) and two smaller proteins. One of the large proteins is termed β ( ... Protein complexes, Protein families, Molecular evolution, Vesicular transport proteins). ... PTBs are protein domains that include NUMB, DAB1 and DAB2. Epsin and AP180 in the ANTH domain are other adaptor proteins that ...

1999). "Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human ... Retinol binding protein 1, cellular, also known as RBP1, is a protein that in humans is encoded by the RBP1 gene. RBP1 is the ... "The transfer of retinol from serum retinol-binding protein to cellular retinol-binding protein is mediated by a membrane ... Alteration of relative protein amounts is linked to the state of differentiation". Biochem. J. 287. ( Pt 2) (2): 383-9. doi: ...

The coatomer subunit delta (delta-COP) is a cytosolic protein complex that binds to motifs and associates with vesicles ... Role of Mammalian Vacuolar Protein-sorting Proteins in Endocytic Trafficking of a Non-ubiquitinated G Protein-coupled Receptor ... There is no evidence of post-translational modifications of the TMEM267 protein found in tissues. According to protein sequence ... The protein was identified as a member of a large group of proteins that comprise a filter in mammalian cells which allow ...

2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ... Scyl1 localizes to the cis-Golgi and ER-Golgi Intermediate Compartment (ERGIC). Scyl1 binds to Coatomer I (COPI) and ... This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a ... The FL protein contains HEAT repeats and a C-terminal coiled coil domain that also contains multiple dibasic motifs, and ends ...

... is a human protein that is encoded by gene which is located on chromosome 11. Also known as ARCN1, it plays a role in ... It is part of the COPI coatomer complex. Xu X, Kedlaya R, Higuchi H, et al. (2010). "Mutation in archain 1, a subunit of COPI ... Protein pages needing a picture, Genes on human chromosome 11, Accuracy disputes from September 2020, All accuracy disputes, ... Peripheral membrane proteins, All stub articles, Human chromosome 11 gene stubs). ...

The SREBF1-SCAP complex is retained in the ER membrane by INSIG1 (insulin-induced gene 1 protein). When sterol levels are ... depleted, INSIG1 releases SCAP and the SREBF1-SCAP complex can be sorted into transport vesicles coated by the coatomer COPII ... In the Golgi apparatus, SREBF1 is cleaved and released as a transcriptionally active mature protein. It is then free to ... White fat cells secrete many proteins acting as adipokines such as resistin, adiponectin, leptin and apelin. An average human ...

2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... 2004). "The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex". J. Biol. Chem. 278 (52): 52689- ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355-64. doi: ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347-55. doi: ...

The proteins lining the inner pore make up the NUP62 complex. On the nucleoplasm side, extra proteins associated with the ring ... the ancestral coatomer elements (ACE). To date, two classes of ACEs have been identified. ACE1 is a 28-helix domain found in ... Different sets of proteins associate on either ring, and some transmembrane proteins anchor the assembly to the lipid bilayer. ... Karyopherins can serve as an importin (transporting proteins into the nucleus) or an exportin (transporting proteins out of the ...

... including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized ... Eugster A, Frigerio G, Dale M, Duden R (August 2000). "COP I domains required for coatomer integrity, and novel interactions ... The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively ... ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene. ADP-ribosylation factor 1 (ARF1) is a member ...

Transmembrane emp24 domain-containing protein 2 is a protein that in humans is encoded by the TMED2 gene. TMED2 has been shown ... Fiedler K, Veit M, Stamnes MA, Rothman JE (September 1996). "Bimodal interaction of coatomer with the p24 family of putative ... two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular ... Majoul I, Straub M, Hell SW, Duden R, Söling HD (July 2001). "KDEL-cargo regulates interactions between proteins involved in ...

Regulator of G-protein signaling 2 is a protein that in humans is encoded by the RGS2 gene. It is part of a larger family of ... 2000). "RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport". Mol. Biol. ... Nlend MC, Bookman RJ, Conner GE, Salathe M (2002). "Regulator of G-protein signaling protein 2 modulates purinergic calcium and ... 1999). "Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in ...