Rabbit syndrome
There is also a low incidence with thioridazine, clozapine, olanzapine, aripiprazole, and low doses of risperidone. Rabbit ...
Timelotem
... and amphetamine-induced behaviour by timelotem as compared with clozapine and haloperidol". Life Sciences. 41 (16): 1909-14. ... instead acts as an atypical antipsychotic drug with similar pharmacology and effects to the structurally related drug clozapine ...
Salvatore Salamone
US 8771972, Salamone, Salvatore J.; Courtney, Jodi Blake & Sard, Howard et al., "Clozapine immunoassay", published 2014-07-08, ...
Dawn Lerner
Edwards tells Beth to give Gavin a dose of Clozapine, an atypical antipsychotic, which kills him. An angry Dawn demands to know ...
Dopamine receptor D4
... and clozapine". Journal of Medicinal Chemistry. 44 (8): 1151-7. doi:10.1021/jm001055e. PMID 11312915. "Dopamine Receptors: D4 ... "Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine". Nature. 350 (6319): ...
Aldehyde oxidase
A select few medications have been identified as potentially significant inhibitors of AO, including Clozapine and ...
5-HT2A receptor
Atypical antipsychotic drugs like clozapine, olanzapine, quetiapine, risperidone and asenapine are relatively potent ... "Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine". ...
Neurotensin
While the atypical antipsychotic drug clozapine augmented PPI normally in neurotensin-deficient mice, the conventional ... Neurotensin-deficient mice also display defects in striatal activation following haloperidol, but not clozapine administration ... restoration by clozapine but no haloperidol, olanzapine, or quetiapine". J. Pharmacol. Exp. Ther. 315 (1): 256-264. doi:10.1124 ...
Treatment of mental disorders
Atypical antipsychotics, such as clozapine block both the D2 Dopamine receptors as well as 5HT2A serotonin receptors. Atypical ...
Batelapine
... (developmental code name CGS-13429) is a structural analogue of clozapine which was investigated as a potential ... Chovan JP, Vermeulen JD (September 1989). "High-performance liquid chromatographic method for a clozapine analogue, CGS 13429, ...
Metiapine
... metiapine has a sulfur atom replacing the nitrogen atom found in dibenzapine derivative antipsychotics like clozapine. ...
F-15063
It has greater efficacy at the 5-HT1A receptors than other antipsychotics, such as clozapine, aripiprazole, and ziprasidone. ...
Olanzapine
Aripiprazole, asenapine, clozapine, quetiapine and olanzapine, in comparison to other antipsychotic drugs, are less frequently ... Investigation on a series of thiophene isosteres on 1 of the phenyl rings in clozapine, a thienobenzodiazepine analog ( ... Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol levels ... Olanzapine was first discovered while searching for a chemical analog of clozapine that would not require hematological ...
Redux (Homeland)
Dennis breaks into Carrie's apartment and replaces some of her Clozapine pills with the pills that Tasneem acquired. Carrie ...
Slabtown (The Walking Dead)
Edwards tells Beth to give Gavin, who is in life support, a dose of Clozapine, an atypical antipsychotic, which kills him. An ... Edwards insists to Beth that he told her to give Gavin Clonazepam, a benzodiazepine, rather than Clozapine. Dawn warns Beth ...
D1-D2 dopamine receptor heteromer
Dziedzicka-Wasylewska M, Faron-Górecka A, Górecki A, Kuśemider M (2008). "Mechanism of action of clozapine in the context of ...
Muscarinic antagonist
Bymaster FP, Falcone JF (2000). "Decreased binding affinity of olanzapine and clozapine for human muscarinic receptors in ...
Pomaglumetad
The oral bioavailability in these rats was found to be 63%. Pomaglumetad demonstrates similar efficacy to clozapine for the ... as well as its metabolites DOPAC and HVA in the prefrontal cortex in a manner similar to the atypical antipsychotic clozapine. ...
Neuroleptic malignant syndrome
Atypical neuroleptics: e.g. olanzapine, clozapine, risperidone Anti-dopaminergic antiemetics: e.g. droperidol Withdrawal of ... However, various atypical antipsychotics such as clozapine, olanzapine, risperidone, quetiapine, and ziprasidone have also been ...
Thought broadcasting
Kopelovich, Sarah L.; Wood, Keith; Cotes, Robert O.; Goldsmith, David R. (July 2020). "Integration of Clozapine-associated Harm ... "Integration of Clozapine-associated Harm Obsessions into Cognitive Behavioral Conceptualization and Treatment Planning for ... "Integration of Clozapine-associated Harm Obsessions into Cognitive Behavioral Conceptualization and Treatment Planning for ...
Case Western Reserve University School of Medicine
... research leading to FDA approval of clozapine, the most advanced treatment for schizophrenia in 40 years at the time; discovery ...
Intermetamorphosis
Some that have been effective in case studies are clozapine, olanzapine, risperidone, quetiapine, sulpiride, trifluoperazine, ...
Psychopathy
For example, a study found that the antipsychotic clozapine may be effective in reducing various behavioral dysfunctions in a ... "Clozapine: an effective treatment for seriously violent and psychopathic men with antisocial personality disorder in a UK high- ...
Olivier Civelli
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature, 350:610-614. ... discovery of the D4 receptor suggested that this receptor may have a particular affinity for the atypical neuroleptic clozapine ...
GNMT
... mice and evaluation of its responses to clozapine and sarcosine treatments". European Neuropsychopharmacology. 22 (8): 596-606 ...
Priapism
... clozapine), antidepressants (most notably trazodone), anti-convulsant and mood stabilizer drugs such as sodium valproate. ...
Glutamate receptor
Memantine, a weak, nonselective NMDA receptor antagonist, was used as an add-on to clozapine therapy in a clinical trial. ... placebo-controlled trial with memantine as add-on therapy to clozapine". J Clin Psychiatry. 70 (10): 1416-23. doi:10.4088/JCP. ...
Anti-Hu associated encephalitis
For hallucinations, delusions, and mood disturbances, second generation antipsychotic agents (e.g., olanzapine, clozapine) are ...
Dopamine receptor D1
Ahlenius S (May 1999). "Clozapine: dopamine D1 receptor agonism in the prefrontal cortex as the code to decipher a Rosetta ... very high selectivity for D1 with negligible affinity for any other receptor Clozapine - partial agonist at D1-like receptors ...
Delusional disorder
... tricyclic-antidepressant imipramine and one which has modest anti-psychotic properties weakly analogous to those of clozapine; ...