Proteins. 65 (3): 549-54. doi:10.1002/prot.21183. PMID 16988956. S2CID 28351121. Gupta G (2020-05-26). "Racing the Clock, COVID ... "Protein-ligand docking: current status and future challenges". Proteins. 65 (1): 15-26. doi:10.1002/prot.21082. PMID 16862531. ... AutoDock consists of two main programs: AutoDock for docking of the ligand to a set of grids describing the target protein; ... Goodsell DS, Sanner MF, Olson AJ, Forli S (August 2020). "The AutoDock suite at 30". Protein Science. 30 (1): 31-43. doi: ...
Evolutionary divergence and convergence in proteins. In Bryson, V.and Vogel, H.J. (editors). Evolving Genes and Proteins. ... The molecular clock hypothesis posits that homologous genes evolve at an approximately constant rate across different species. ... For example, an analysis of the top BLAST hits of protein sequences in the bacteria Thermotoga maritima revealed that most hits ... Phylogenetic methods tend to be applied to genes or protein sequences as basic evolutionary units, which limits their ability ...
Emile Zuckerkandl and Linus Pauling name their concept of the molecular clock. The Parma wallaby, thought for around 70 years ... ISBN 0-674-53985-0. Zuckerkandl, E.; Pauling, L. (1965). "Evolutionary Divergence and Convergence in Proteins". In Bryson, B.; ... Morgan, Gregory J. (1998). "Emile Zuckerkandl, Linus Pauling, and the Molecular Evolutionary Clock, 1959-1965". Journal of the ... Vogel, H. (eds.). Evolving Genes and Proteins. New York: Academic Press. pp. 97-166. ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... this protein has not been functionally characterized.[2] Holin Lysin Transporter Classification Database Reddy, Bhaskara L.; ...
Molecular evolution Molecular clock UPGMA Jukes TH, Cantor CR (1969). Evolution of Protein Molecules. New York: Academic Press ... Hasegawa M, Kishino H, Yano T (1985). "Dating of the human-ape splitting by a molecular clock of mitochondrial DNA". Journal of ... a codon is three bases and codes for one amino acid in a protein). There are 4 3 = 64 {\displaystyle 4^{3}=64} codons, but the ... amino acids that make up proteins), one would find there are 209 parameters. However, when studying coding regions of the ...
"Protein BLAST: search protein databases using a protein query". blast.ncbi.nlm.nih.gov. Retrieved 2018-05-05. EMBL-EBI. "EBI ... C9orf43 divergence is moderate based on the molecular clock hypothesis. C9orf43 is seen to diverge more quickly than cytochrome ... The protein does not contain signal peptides or mitochondrial targeting signals indicating the protein is not predicted to be ... Isoform X1 protein abundance is predicted to be normal with normal expression. Composition analysis of C9orf43 showed an above ...
Variations in the C-terminal region of each of their proteins suggest functional divergence between the Kai clock proteins, ... Egli M (August 2014). "Intricate protein-protein interactions in the cyanobacterial circadian clock". The Journal of Biological ... Egli M (August 2014). "Intricate protein-protein interactions in the cyanobacterial circadian clock". The Journal of Biological ... Kai proteins regulate genome-wide gene expression. Protein KaiA enhances the phosphorylation of protein KaiC by binding to the ...
"Proteins that reprogram cells can turn back mice's aging clock". Retrieved 19 December 2016.. ... Oxidative Protein Damage and Expression of Heat Shock Proteins, Inflammatory Factors, and Mitochondrial Complexes in Arctica ... mTOR, a protein that inhibits autophagy, has been linked to ageing through the insulin signalling pathway. mTOR functions ... For example, a waste product called lipofuscin is formed by a complex reaction in cells that binds fat to proteins. This waste ...
Another essential component of this circadian clock mechanism is that the PER protein contains a PAS domain, which has been ... "JRKL - Jerky protein homolog-like - Homo sapiens (Human) - JRKL gene & protein". www.uniprot.org. Retrieved 2019-04-11. ... The Jrk mutation deletes much of the gene that encodes for the glutamine (Q)-rich C terminus of the protein. This region is ... "Clk Clock [Drosophila melanogaster (fruit fly)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2019-04-11. "FlyBase Allele ...
Saey TJ (15 December 2016). "Proteins that reprogram cells can turn back mice's aging clock". Retrieved 19 December 2016. ... oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica ... as well as increase extracellular proteins such as collagen and fibronectin (important proteins for cell proliferation). ... mTOR, a protein that inhibits autophagy, has been linked to ageing through the insulin signalling pathway. mTOR functions ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... However, these proteins were retrieved when functionally characterized holins from the T-A Hol family (TC# 1.E.43) were BLASTED ... Most BAH proteins are between 125 and 140 amino acyl residues (aas) in length and exhibit 4 transmembrane segments (TMSs), ... A representative list of proteins belonging to the BAH family can be found in the Transporter Classification Database. Holin ...
Holin Lysin Transporter Classification Database Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks ... PH-2 family proteins are of 130 to 210 amino acyl residues (aas) in length and may exhibit 1 or 2 transmembrane segments (TMSs ... A representative list of proteins belonging to the PH-2 family can be found in the Transporter Classification Database. ...
Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... This protein is functionally uncharacterized and does not appear to be homologous to other holins. It does, however, show 31% ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... While many of the proteins belonging to this family are annotated in holins, they remain functionally uncharacterized. Holin ... A representative list of the proteins belonging to this family can be found in the Transporter Classification Database. ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... While annotated as holins, these proteins remain functionally uncharacterized. A representative list of proteins belonging to ... The Putative Listeria Phage Holin (LP-Hol) Family (TC# 1.E.51) consists of several small proteins of 41 amino acyl residues ( ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... although BP-Hol proteins remain functionally uncharacterized. A representative list of the proteins belonging to the BP-Hol ... These proteins are of 60 to 110 amino acyl residues (aas) in length and exhibit 1 or 2 transmembrane segments (TMSs). Some are ... protein".www.uniprot.org. Retrieved 2016-03-29. Gründling, Angelika; Manson, Michael D.; Young, Ry (2001-07-31). "Holins kill ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... This protein brings up other glycosyltransferases in a NCBI BLAST search. The adjacent gene encodes a small protein of 132 aas ... This protein has the UniProt accession number of S2E3C4. Paralogues are found in this same organism (Candidatus Nitrosoarchaeum ... The "toxin" gene encodes a soluble protein of 325 aas stated as belonging to the "Glycosyltransferase GBT-type Superfamily". ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... The Putative Treponema 4 TMS Holin (Tre4Hol) Family (TC# 1.E.49) consists of several proteins from Treponema species. They ...
Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... The putative holin-like toxin (Hol-Tox) family (TC# 1.E.42) consists of many small proteins, between 34 and 48 amino acyl ... A representative list of proteins belonging to the Hol-Tox family can be found in the Transporter Classification Database. ... "Functional characterization of a new holin-like antibacterial protein coding gene tmp1 from goat skin surface metagenome". ...
PMID 25157079.. Wang, IN; Smith, DL; Young, R (2000). "Holins: the protein clocks of bacteriophage infections". Annu. Rev. ... Phage-like transmembrane protein', 'YeaQ protein', etc. in the NCBI protein database. As of early 2016, they remain ... These proteins are related to the RDD family (TC# 9.B.45) in the conserved domain database. A representative list of proteins ... Homologues include thousands of diverse phage and bacterial proteins between 80 and 140 amino acyl residues (aas) in length ...
Holin Lysin Transporter Classification Database Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of ... Although annotated as phage proteins or holins, NP-Holin proteins are not yet functionally characterized, thus more research is ... The Neisserial Phage-associated Holin (NP-Holin) Family (TC# 1.E.22) is a family of small proteins, between 47 - 53 amino acyl ... A representative list of proteins belonging to the NP-Holin family can be found in the Transporter Classification Database. ...
Wang, Ing-Nang; Smith, David L.; Young, Ry (October 2000). "Holins: The Protein Clocks of Bacteriophage Infections". Annual ... The ArpQ Holin (ArpQ Holin) Family (TC# 1.E.15) consists of a single holin-like protein 58 amino acyl residues (aas) in length ... with 2 transmembrane segments (TMSs). This protein is encoded by the arpQ gene in Enterococcus hirae. While annotated as a ...
Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... "Phosphate concentration and the putative sensor kinase protein CckA modulate cell lysis and release of the Rhodobacter ...
Wang I, Smith DL, Young R (2000). "Holins: The Protein Clocks of Bacteriophage Infections". Annual Review of Microbiology. 54 ( ... The T4 Holin Family (TC# 1.E.8) is a group of putative pore-forming proteins that does not belong to one of the seven holin ... The protein is highly hydrophilic with 49 acidic and basic residues distributed along its length and a single putative ... The phage T4 T-holin (lysis protein) is identical to the holin from phage K3 and nearly identical to that from phage ARI. ...
Wang, IN; Smith, DL; Young, R (2000). "Holins: the protein clocks of bacteriophage infections". Annu. Rev. Microbiol. 54: 799- ... The Mycobacterial Phage PBI1 Gp36 Holin (Gp36 Hol) Family (TC# 1.E.39) consists of a single protein, Gp36 of Mycobacterial ... this protein has not been functionally characterized. Holin Lysin Transporter Classification Database Reddy, BL; Saier, MH ( ...
PMID 25157079.. Wang, IN; Smith, DL; Young, R (2000). "Holins: the protein clocks of bacteriophage infections". Annu. Rev. ... These proteins are short, 55 to 71 amino acyl residues (aas) in length, and exhibit a single transmembrane segment (TMS). A ... representative list of proteins belonging to the T1 Holin family can be found in the Transporter Classification Database. Holin ...
Wang, I. N.; Smith, D. L.; Young, R. (2000-01-01). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... and a homologous uncharacterized protein (TC# 1.E.59.1.2; 75 aas and 2 TMSs). These proteins are of particular interest because ...
Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of bacteriophage infections". Annual Review of ... this protein does not show appreciable sequence similarity to any other proteins in the NCBI protein database. Holin Lysin ... It is a putative uncharacterized protein from Xanthomonas phage Xp15. This protein corresponds to sequence 68 from patent US ... The Xanthomonas Phage Holin (XanPHol) Family (TC# 1.E.45) consists of a single protein (Putative holin; TC# 1.E.45.1.1) of 64 ...
... protein". www.uniprot.org. Retrieved 2016-03-30. Wang, I. N.; Smith, D. L.; Young, R. (2000). "Holins: the protein clocks of ... BhlA proteins are generally about 67 to 80 amino acyl residues (aas) in length and exhibit a single N-terminal transmembrane ... A representative list of proteins belonging to this family can be found in the Transporter Classification Database. Holin Lysin ... Transporter Classification Database "BPUM_2741 - Uncharacterized protein - Bacillus pumilus (strain SAFR-032) - BPUM_2741 gene ...
Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.[5][6][7] ... 1989). "Complementary homeo protein gradients in developing limb buds". Genes Dev. 3 (5): 641-50. doi:10.1101/gad.3.5.641. PMID ... HOXD8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH) ... "The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins". EMBO J. 13 (14): 3339-47. PMC ...
Rubidium and caesium are often used in atomic clocks.[205] Caesium atomic clocks are extraordinarily accurate; if a clock had ... The balance between potassium and sodium is maintained by ion transporter proteins in the cell membrane.[231] The cell membrane ... One of the best-known applications of the pure elements is the use of rubidium and caesium in atomic clocks, of which caesium ... atomic clocks form the basis of the second. A common application of the compounds of sodium is the sodium-vapour lamp, which ...
The albumin (9) further protects the embryo and serves as a reservoir for water and protein. The allantois (8) is a sac that ... Lee, Michael SY; Cau, Andrea; Darren, Naish; Gareth J., Dyke (2013). "Morphological Clocks in Paleontology, and a Mid- ... The yolk sac (2) surrounding the yolk (3) contains protein and fat rich nutrients that are absorbed by the embryo via vessels ( ... "Error in Estimation of Rate and Time Inferred from the Early Amniote Fossil Record and Avian Molecular Clocks". Journal of ...
Clock * sw:Clock. Clothing * sw:Clothing. Cloud * sw:Cloud. Coffee * sw:Coffee. Cold War * sw:Cold War. Colonialism * sw: ... Protein * sw:Protein. Protestant Reformation * sw:Protestant Reformation. Protist * sw:Protist. Psychology * sw:Psychology. ...
Won, Hyosig; Renner, Susanne (august 2006). "Dating Dispersal and Radiation in the Gymnosperm Gnetum (Gnetales)-Clock ... of Cycas taitungensis and 56 cp Protein-Coding Genes of Gnetum parvifolium: Insights into cpDNA Evolution and Phylogeny of ...
"The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε" (PDF). Cell. 94 (1): 97-107 ... "Regulation of nuclear entry of the Drosophila clock proteins period and timeless" (PDF). Neuron. 17 (5): 808-810. doi:10.1016/ ... "double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation" (PDF). Cell. 94 (1): 83-95. doi: ... Young's lab is also attributed with the discovery of the timeless and doubletime genes, which makes proteins that are also ...
Hubby, J. L. Protein Differences in Drosophila. I. Drosophila melanogaster. Genetics. 1963, 48 (6): 871-879. PMC 1210521. PMID ... 90-91; Zuckerkandl, "On the Molecular Evolutionary Clock", p. 34 *^ Dietrich, "Paradox and Persuasion", pp. 90-91; Morgan, " ... De novo origination of a new protein-coding gene in Saccharomyces cerevisiae. Genetics. 2008, 179 (1): 487-496. PMC 2390625. ... Knowles DG, McLysaght A. Recent de novo origin of human protein-coding genes. Genome Res. 2009, 19 (10): 1752-1759. PMC 2765279 ...
Rb · RBL1(英语:Retinoblastoma-like protein 1) · RBL2(英语:Retinoblastoma-like protein 2) ... ATOH1 · AhR · AHRR · ARNT · ASCL1 · BHLHB2 · BMAL(ARNTL、ARNTL2) · CLOCK · EPAS1 · HAND(1、2) · HES(5、6) · HEY(1、2、L) · HES1 · ... protein homodimerization activity. · sequence-specific DNA binding. · metal ion binding. · protein heterodimerization activity ... FOXP2(Forkhead box protein P2 (FOXP2))基因,即叉头框P2基因,是一个与言语功能的发育有关的基因。在人
ATOH1 • AhR • AHRR • ARNT • ASCL1 • BHLHB2 • BMAL (ARNTL, ARNTL2) • CLOCK • EPAS1 • HAND (1, 2) • HES (5, 6) • HEY (1, 2, L) • ... Bernstein PL, Herrick DJ, Prokipcak RD, Ross J (1992). "Control of c-myc mRNA half-life in vitro by a protein capable of ... Blackwood EM, Eisenman RN (1991). "Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex ... 1988). "A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is ...
They serve as protein and starch storage units serving as a nutrient source for newly developed plants. ... Of considerable interest is how this process appears to reset the aging clock.[16] ...
R. L. Wysong (1976). "5: Origin of Proteins". The Creation-evolution Controversy (implications, Methodology and Survey of ... "molecular clock", which enabled the neutral theory of molecular evolution.[365] ... for their studies of the structures of hemoglobin and globular proteins.[269] ... awarded the 2001 Nobel Prize in Physiology or Medicine along with Leland Hartwell and Tim Hunt for their discoveries of protein ...
This method is not very accurate since the composition of proteins varies greatly and proteins with none of these amino acids ... Deep Space Atomic Clock. *Inertial Stellar Compass. *Venetia Burney Student Dust Counter ... The concentration of a protein can be estimated by measuring the OD at 280 nm due to the presence of tryptophan, tyrosine and ... Spectrophotometry is an important technique used in many biochemical experiments that involve DNA, RNA, and protein isolation, ...
Savini I, Rossi A, Pierro C, Avigliano L, Catani MV (April 2008). "SVCT1 and SVCT2: key proteins for vitamin C uptake". Amino ... According to molecular clock dating, these two suborder primate branches parted ways about 63 to 60 million years ago.[143] ... The HIFalpha prolyl hydroxylases, termed PHDs/EGLNs (prolyl hydroxylase domain proteins/EGL nine homologues), bind to a ... which lose SVCT proteins during maturation.[105] In both vitamin C synthesizers (example: rat) and non-synthesizers (example: ...
These "molecular clocks", however, are fallible, and provide only a very approximate timing: for example, they are not ... by comparing sequences of DNA or proteins. The result of a successful analysis is a hierarchy of clades - groups that share a ... "molecular clock".[12] Techniques developed in engineering have been used to analyse how ancient organisms might have worked, ... Although this early study compared proteins from apes and humans, most molecular phylogenetics research is now based on ...
"Protein Spotlight (29). Retrieved 14 September 2006.. *^ Weimann, Anya (4 July 2007) Evolution of platypus venom revealed. ... Molecular clock and fossil dating suggest platypuses split from echidnas around 19-48 million years ago.[71] ... composed largely of defensin-like proteins (DLPs), three of which are unique to the platypus.[30] The DLPs are produced by the ...
Many flowering plants (angiosperms) use a photoreceptor protein, such as phytochrome or cryptochrome,[1] to sense seasonal ... Cryptochromes absorb blue light and UV-A. Cryptochromes entrain the circadian clock to light.[6] It has been found that both ... with the rhythms of the circadian clock that allows plants to measure the length of the night. Other than flowering, ...
The ACTH receptor is a seven-membrane-spanning G protein-coupled receptor.[7] Upon ligand binding, the receptor undergoes ... organization and coordination of central and peripheral clocks". Annual Review of Physiology. 72: 517-49. doi:10.1146/annurev- ... and their associated electron transfer proteins.[8] This effect is observed over several hours.[8] ... and subsequent activation of protein kinase A. ... Protein pages needing a picture. *All articles with unsourced ...
Some migratory birds have adapted to use protein from many parts of their bodies, including protein from the intestines, as ... Birds that use the sun compensate for the changing position of the sun during the day by the use of an internal clock.[62] ... Domesticated birds raised for meat and eggs, called poultry, are the largest source of animal protein eaten by humans; in 2003 ... Lee, Michael SY; Cau, Andrea; Darren, Naish; Gareth J., Dyke (May 2014). "Morphological Clocks in Paleontology, and a Mid- ...
It is likely that they simply did not exist, and that the molecular clock runs fast during major evolutionary radiations.[101] ... "Assessing the Cretaceous superordinal divergence times within birds and placental mammals by using whole mitochondrial protein ...
Carnivorous and vampire bats consume large amounts of protein and can output concentrated urine; their kidneys have a thin ... Jones, K. E.; Bininda-Emonds, O. R. P.; Gittleman, J. L. (2005). "Bats, clocks, and rocks: diversification patterns in ... is due to the upregulation of bone morphogenetic proteins (Bmps). During embryonic development, the gene controlling Bmp ...
These deletions and mutations lead to the production of an abnormal or nonfunctional version of the RAI1 protein. RAI1 is a ... such as CLOCK.[8] The groups led by James Lupski (Baylor College of Medicine) and Sarah Elsea (Virginia Commonwealth University ... "Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the ...
Many feeds designed for pregnant and lactating mares provide the careful balance required of increased protein, increased ... are still to this day bred to have a combination of explosive speed that exceeds the Thoroughbred on short distances clocked as ...
This venom is derived from b-defensins, proteins that are present in mammals that create holes in viral and bacterial pathogens ... Molecular clock and fossil dating give a wide range of dates for the split between echidnas and platypuses, with one survey ... Monotreme milk contains a highly expressed antibacterial protein not found in other mammals, perhaps to compensate for the more ... a protein necessary for egg shell formation) is shared with birds; the presence of this symplesiomorphy suggests that the ...
This suggests that animals have a biological clock that can serve as a CS. This method has also been used to study timing ... Presynaptic activation of protein kinase A and postsynaptic activation of NMDA receptors and its signal transduction pathway ... An example of conditioned hunger is the "appetizer effect." Any signal that consistently precedes a meal, such as a clock ... CREB is also necessary for conditioning related plasticity, and it may induce downstream synthesis of proteins necessary for ...
In order to replicate, poxviruses produce a variety of specialized proteins not produced by other DNA viruses, the most ... The wide range of dates is due to the different records used to calibrate the molecular clock. One clade was the variola major ... protein and electrolytes beyond the capacity of the body to replace or acquire, and fulminating sepsis.[59] ... The mutation rate of this virus is well modeled by a molecular clock. Diversification of strains only occurred in the 18th and ...
Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G) ... protein domain specific binding. • RNA polymerase II transcription factor activity, sequence-specific DNA binding. ... HNF-3G is a member of the forkheadclass of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional ... Dintilhac A, Bernués J (2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid ...
Macdougall, Doug (2008). Nature's Clocks: How Scientists Measure the Age of Almost Everything. Berkeley, California: University ... Unburnt bone can be tested; it is usual to date it using collagen, the protein fraction that remains after washing away the ... an organic protein found in shell, but it constitutes only 1-2% of shell material.[55] ...
10] Some proteins can become infectious agents. This is the name of those misfolded proteins that are responsible for mad cow ... Match length is determined by either a game clock or the number of questions in a packet.[2][16] In most formats, a game ends ... 10] Name this class of molecules that make up proteins, examples of which include tryptophan, alanine, and lysine.. ANSWER: ...
... which is regulated by the transformer protein in many different insects.[68] Mdmd causes male development by negatively ... "Time flies, a new molecular time-scale for brachyceran fly evolution without a clock". Systematic Biology. 52 (6): 745-56. doi ... and possibly other proteins and polysaccharides of medical value.[41] ... "Sustainable production of housefly (Musca domestica) larvae as a protein-rich feed ingredient by utilizing cattle manure" ...
Working on protein sequences, they eventually (1971) determined that apes were closer to humans than some paleontologists ... Among these researchers, Allan C. Wilson and Vincent Sarich were pioneers in the development of the molecular clock for humans ... because studies have found evidence for a slowing of the molecular clock as apes evolved from a common monkey-like ancestor ... "Variation in the molecular clock of primates". Proceedings of the National Academy of Sciences. 113 (38): 10607-10612. doi ...