Safer and more effective clinical trials. Evolution[edit]. This section may stray from the topic of the article. Please help ... "Journal of Evaluation in Clinical Practice. 18 (1): 56-62. doi:10.1111/j.1365-2753.2010.01522.x. ISSN 1365-2753. PMID 20698917. ...
Topics in Magnetic Resonance Imaging. 25 (1): 31-37. doi:10.1097/RMR.0000000000000076. "Clinical Trials". Janine M. Lupo; ... The majority of clinical studies utilizing 13C hyperpolarization are currently studying pyruvate metabolism in prostate cancer ...
ongoing microbicide clinical trials "avac" Check ,url= value (help). Retrieved October 2010. Check date values in: ,access-date ... permanent dead link] World Health Organization (2002). "HIV/AIDS Topics: Microbicides". Geneva: World Health Organization. ... Additionally, clinical trials have not demonstrated these agents to be effective at preventing HIV transmission.[citation ... See Carrageenan#Medical Uses The phase III clinical trial for carrageenan-based Carraguard showed that it had no statistical ...
... clinical research including clinical trials; endocrinology; epidemiology and prevention; experimental therapeutics, molecular ... Some of the topics include biochemistry; chemical, physical, and viral carcinogenesis and mutagenesis; ... Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational ... The journal publishes significant, original studies, reviews, and perspectives on all areas of basic, clinical, translational, ...
See Trivia, and avoid useless statements like "More research is needed". Wikipedia is not a directory of clinical trials or ... To create a new topic, slick [new section] at the top of the page, give the section a title, and leave your comment. New topics ... For example, the results of an early-stage clinical trial are unlikely to be appropriate for inclusion in the Treatment section ... In medicine, primary sources include clinical trials, which test new treatments; secondary sources include meta-analyses, which ...
Clinical Cancer Research; Clinical Trials. 6 (7): 2677-84. PMID 10914709. Avendano, Carmen; Menendez, J. Carlos (April 2008). ... "Oral Complications of Chemotherapy and Head/Neck Radiation". Cancer Topics - Coping with Cancer. National Cancer Institute. ... In clinical trials for mesothelioma, folic acid and B12 supplementation reduced the frequency of adverse events.) It is also ... NCCN Clinical Practice Guidelines in Oncology: Non-small Cell Lung Cancer V.2.2009 available from www.nccn.org Azzoli CG, Kris ...
Lechat, P. (2008). "Clinical pharmacology of beta-blockers in cardiology: trial results and clinical applications". Hot Topics ... Clinical trials started in the summer of 1964 and a year later, propranolol was launched under the trade name Inderal, only two ... The launch took place in November 1963 when many small-scale clinical trials had proved their effectiveness in angina and ... Although DCI had no clinical utility, a change in the compound did provide a clinical candidate, pronethalol, which was ...
It was in phase II clinical trials in 2008 but appears to have been discontinued as it is no longer in the company's ... Teegarden BR, Al Shamma H, Xiong Y (2008). "5-HT(2A) inverse-agonists for the treatment of insomnia". Current Topics in ... "Efficacy Study of LY2422347 to Treat Insomnia - Full Text View - ClinicalTrials.gov". "Eli Lilly and Company » Research ...
... which are much higher than those seen in randomized clinical trials[62] have been the topic of extensive debate and discussion. ... The author of one study argued that adverse events are more common in clinical practice than in randomized clinical trials.[56] ... Norata GD, Tibolla G, Catapano AL (October 2014). "Statins and skeletal muscles toxicity: from clinical trials to everyday ... Randomized controlled trials have found these foodstuffs to reduce circulating cholesterol, but the quality of the trials has ...
Clinical trials have been initiated to test the effectiveness of certain worms in treating some allergies. It may be that the ... For more information on this topic, see Helminthic therapy. In the early stages of allergy, a type I hypersensitivity reaction ... The authors concluded that, based on rigorous clinical trials of all types of homeopathy for childhood and adolescence ailments ... systematic review of randomized clinical trials". Mayo Clin. Proc. 82 (1): 69-75. doi:10.4065/82.1.69. PMID 17285788. "Archived ...
... clinical trials; health and adverse effects; fortification; traditional Chinese medicine and other folk/ethnic supplement ... The subset will retrieve dietary supplement-related citations on topics including, but not limited to: chemical composition; ...
In addition to Hantavax three more vaccine candidates have been studied in I-II stage clinical trials. They include a ... List of vaccine topics Seoul virus Gou virus Vaccine-naive Schmaljohn, C. S. (2012). "Vaccines for hantaviruses: Progress and ... Field trial of an inactivated vaccine against hemorrhagic fever with renal syndrome in humans. Arch Virol. 1990;1(Suppl):35-47 ... "Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever". ClinicalTrials.gov. ...
For example, results of an early-stage clinical trial would not be appropriate in the Treatment section on a disease because ... which can be useful when outlining a topic. Systematic reviews use sophisticated methodology to address a particular clinical ... In medicine, primary sources include clinical trials, which test new treatments. Broadly speaking, reviews may be narrative or ... Some systematic reviews also include a statistical meta-analysis to combine the results of several clinical trials to provide ...
Since 1992, the journal has published the proceedings of Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) ... The Journal of Rheumatology is a peer-reviewed medical journal addressing topics in rheumatology and arthritis. It is an ...
Karonudib, an MTH1 inhibitor, is currently being evaluated a phase I clinical trial for safety and tolerability. A potent and ... Research into this topic is ongoing. MTH1 is a potential drug target to treat cancer, however there are conflicting results ... This makes it a topic of interest in cancer research, both as a potential method for healthy cells to prevent cancer and a ... "MTH1, A Phase I, Study on Tumors Inhibition, First in Human, First in Class (MASTIFF)". ClinicalTrials.gov. U.S. National ...
... whereas a clinical trial case will typically be assessed for causality by the clinical trial investigator and/or the license ... The CIOMS, a part of the WHO, is a globally oriented think tank that provides guidance on drug safety related topics through ... The variables in a clinical trial are specified and controlled, but a clinical trial can never tell you the whole story of the ... Also known as SAE (serious adverse event) reporting from clinical trials, safety information from clinical studies is used to ...
Discussion topics when setting up an experimental designEdit. An experimental design or randomized clinical trial requires ... James Lind carried out a systematic clinical trial to compare remedies for scurvy.[1] This systematic clinical trial ... Systematic clinical trialsEdit. This section possibly contains original research. Please improve it by verifying the claims ... Some of the following topics have already been discussed in the principles of experimental design section:. *How many factors ...
Kowey said the book's main weakness was a lack of focus on clinical issues - both in topics covered and author selection. He ... examines drugs in clinical trial at the time of publication. The chemical structure of existing drugs is not covered. Overall, ... noted that bringing drugs to the marketplace is expensive and proof of concept clinical trials are necessary to justify the ... Its 21 chapters cover a variety of topics related to cardiac arrhythmia and electrophysiology, primarily reviewing known ...
... results of clinical trials, and research findings. Ophthalmology also publishes major reviews of specific topics by ... Topics include new diagnostic and surgical techniques, treatment methods, instrument updates, the latest drug findings, ...
The earliest publication of a controlled clinical trial appears to be from 1945.[27] Researchers continued to work on this ... started publishing research on the topic and also published a book "Vitamin C and the Common Cold" in 1970.[28] A revised and ... A meta-analysis of 44 clinical trials has shown a significant positive effect of vitamin C on endothelial function when taken ... cannot be recommended outside of a clinical trial."[43] A 2015 review added: "There is no high-quality evidence to suggest that ...
... interventions that are being tested for weight management in overweight and obese adults in primary care clinical trials.[ ... She contributed to several other topics, including the investigation of the influence of socioeconomic status and stress on ... She completed her PhD in 1986, and in 1987 was promoted to senior lecturer in clinical psychology and consultant clinical ... Jane Wardle FBA FMedSci (30 October 1950 - 20 October 2015) was a professor of clinical psychology and director of the Cancer ...
Climate ensemble Climograph Clinical significance Clinical study design Clinical trial Clinical utility of diagnostic tests ... of graphical methods List of fields of application of statistics List of stochastic processes topics Lists of statistics topics ... clinical trials) Minimum chi-square estimation Minimum distance estimation Minimum mean square error Minimum-variance unbiased ... End point of clinical trials Energy distance Energy statistics (disambiguation) Encyclopedia of Statistical Sciences (book) ...
They work together to assess the evidence for the guideline topic (e.g. clinical trials of competing products) before preparing ... Before an appraisal, the Advisory Committee on Topic Selection (ACTS) draws up a list of potential topics of clinical ... It was set up as the National Institute for Clinical Excellence in 1999, and on 1 April 2005 joined with the Health Development ... The idea of what was originally termed a National Institute for Clinical Excellence took root when Labour came to power having ...
Reviewing clinical trials involving phytosterol supplementation, the FDA concluded that when consumed in the range of 1 to 3 ... Patterson, CA (July 2006). "Phytosterols and stanols: Topic 10075E" (PDF). Agriculture and Agri-Food Canada, Government of ... Plant sterols and stanols, when compared head to head in clinical trials, have been shown to equally reduce cholesterol levels ... Trials looking at high doses (> 4 g/day) of plant sterols or stanols are very limited, and none have yet to be completed ...
... as well as clinical trials. The Journal of Biological Rhythms covers topics in chronobiology, namely circadian and seasonal ... Early research topics included "splitting," circannual rhythmicity, photoperiodic time measurement, and circadian pacemaker ... The journal also publishes special publication collections consisting of selected articles on a chosen topic. These collections ...
... clinical statisticians and pharmacologists, use clinical trials to reveal such effects, allowing physicians to offer a ... teaching includes such topics as doctor-patient communication, ethics, the art of medicine,[96] and engaging in complex ... Gorski, DH; Novella, SP (September 2014). "Clinical trials of integrative medicine: testing whether magic works?". Trends in ... Hróbjartsson A, Gøtzsche PC (May 2001). "Is the placebo powerless? An analysis of clinical trials comparing placebo with no ...