A long terminal repeat (LTR) is a pair of identical sequences of DNA, several hundred base pairs long, which occur in ... Retroviruses such as human immunodeficiency virus (HIV) use this basic mechanism. As 5' and 3' LTRs are identical upon ... The LTRs then mediate integration of the DNA via an LTR specific integrase into another region of the host chromosome. ... Human Retroviruses and AIDS, 1998. Krebs, Fred C.; Hogan, Tricia H.; Quiterio, Shane; Gartner, Suzanne; Wigdahl, Brian (2001 ...
Genes on human chromosome 9, Wikipedia articles incorporating text from the United States National Library of Medicine, Human ... The NDUFA8 gene is located on the q arm of chromosome 9 in position 33.2 and spans 27,354 base pairs. The gene produces a 20 ... Related pseudogenes have also been identified on four other chromosomes. The human NDUFA8 gene codes for a subunit of Complex I ... Smeitink J, van den Heuvel L (1999). "Human mitochondrial complex I in health and disease". Am. J. Hum. Genet. 64 (6): 1505-10 ...
Chromosome 8 open reading frame 82 is a protein encoded in humans by the C8orf82 gene. C8orf82 is a gene located on the minus ... The Human Protein Atlas entry on C8orf82 NCBI GEO Profile entry on C8orf82 GDS3113 Unigene entry for C8orf82 (Uncharacterized ... The mRNA produced by the C8orf82 gene is 1,979 base pairs long with coding sequence that starts at base 159 and ends at base ... Isoleucine (0.5%) and lysine (1.4%) within C8orf82 were found to occur in lower frequencies compared to other normal human ...
The NDUFAF6 gene is located on the q arm of chromosome 8 in position 22.1 and spans 222,728 base pairs. The gene produces a ... NADH:ubiquinone oxidoreductase complex assembly factor 6 is a protein that in humans is encoded by the NDUFAF6 gene. The ... Articles with short description, Short description matches Wikidata, Human genes, Wikipedia articles incorporating text from ... GRCm38: Ensembl release 89: ENSMUSG00000050323 - Ensembl, May 2017 "Human PubMed Reference:". National Center for Biotechnology ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 22). ... "Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1". Mol. Cell. 14 ... "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489-95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID ... Habu T, Taki T, West A, Nishimune Y, Morita T (1996). "The mouse and human homologs of DMC1, the yeast meiosis-specific ...
NCBI (National Center for Biotechnology Information) (Genes on human chromosome 2). ... Its genomic mRNA length is 9,807 base pairs. Its genomic DNA length is 24.3 kilobases. It has 8 exons, 4 common splice forms. ... PLEKHM3 is a valid, protein coding gene that is located on the minus strand of the q-arm of chromosome 2. Its exact location is ... Pleckstrin Homology domain containing Family M Member 3, or PLEKHM3, is the hypothetical protein that in humans is encoded by ...
The PLA2G6 gene is located on the p arm of chromosome 22 at position 13.1 and it spans 80,605 base pairs. The PLA2G6 gene ... December 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489-495. Bibcode:1999Natur.402..489D. doi: ... Different from rodent PLA2G6, which is known to share 90% overall amino acid sequence identity with that of the humans, the ... Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ (September 2006). "Characterization of the human patatin-like ...
The COA5 gene is located on the q arm of chromosome 2 at position 11.2 and it spans 9,195 base pairs. The COA5 gene produces an ... Cytochrome c oxidase assembly factor 5 is a protein that in humans is encoded by the COA5 gene. This gene encodes an ortholog ... "COA5 - Cytochrome c oxidase assembly factor 5 - Homo sapiens (Human) - COA5 gene & protein". www.uniprot.org. Retrieved 2018-08 ... which is conserved in the 74-amino acid deduced human protein. An example of the twin CX9C would be a repeated motif of 2 ...
Animals Plants Other Eukaryotes Karyotype of a human being. It shows 22 homologous autosomal chromosome pairs, both the female ... As other non-human extant hominidae have 48 chromosomes it is believed that the human chromosome 2 is the result of the merging ... Shared synteny of human chromosome 17 loci in Canids (archived 24 September 2015) An atlas of the chromosome numbers in animals ... "Evidence for an ancestral alphoid domain on the long arm of human chromosome 2". Human Genetics. 89 (2): 247-9. doi:10.1007/ ...
Genes on human chromosome 8, All articles with failed verification, Articles with failed verification from November 2019). ... and spans 27,566 base pairs. There is a promoter approximately 4,000 base pairs upstream as predicted by the tool ElDorado by ... Li Y, Dong X, Yin Y, Su Y, Xu Q, Zhang Y, Pang X, Zhang Y, Chen W (December 2005). "BJ-TSA-9, a novel human tumor-specific gene ... Protein FAM83A (family member with sequence similarity 83) also known as tumor antigen BJ-TSA-9 is a protein that in humans is ...
Females typically have two X chromosomes, and males typically have a Y chromosome and an X chromosome. At an early stage in ... As development proceeds, one of the pairs of ducts develops while the other regresses. This depends on the presence or absence ... Most mammals, including humans, have an XY sex-determination system: the Y chromosome carries factors responsible for ... Sexual differentiation in humans is the process of development of sex differences in humans. It is defined as the development ...
Chromosome 1 open reading frame (C1orf167) is a protein which in humans is encoded by the C1orf167 gene. The NCBI accession ... The mRNA sequence was found to be 4689 base pairs in length. It can be located on chromosome 1 at position 1p36.22 on the plus ... "C1orf167 chromosome 1 open reading frame 167 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2019-04-22 ... "C1orf167 chromosome 1 open reading frame 167 [ Homo sapiens (human) ])". NCBI. Retrieved February 9, 2019. "C1orf167 Gene". www ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 11). ... It has 4,591 base pairs with 8 exons, and it is located on the minus strand of chromosome 11, at 11q13.2, in humans. There are ... which is located on human chromosome 19. YIF1A has 238 identified orthologs. The ortholog contains vertebrates such as mammals ... "Human BLAT Search". genome.ucsc.edu. Retrieved 2020-07-02. Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method ...
"An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of ... Genes on human chromosome X, Nudix hydrolases, All stub articles, Human chromosome X gene stubs). ... 2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325-37. Bibcode:2005Natur.434..325R. doi:10.1038/ ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene. This gene is a member of the ... Tamura T, Izumikawa Y, Kishino T, Soejima H, Jinno Y, Niikawa N (1994). "Assignment of the human PAX4 gene to chromosome band ... Pilz AJ, Povey S, Gruss P, Abbott CM (1993). "Mapping of the human homologs of the murine paired-box-containing genes". ... v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome 7, Wikipedia ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 8, Wikipedia articles ... "The human B22 subunit of the NADH-ubiquinone oxidoreductase maps to the region of chromosome 8 involved in branchio-oto-renal ... The NDUFB9 gene is located on the q arm of chromosome 8 in position 13.3 and is 10,884 base pairs long. The NDUFB9 protein ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ...
SMN1 is located in a telomeric region of human chromosome 5 and also contains SMN2 in a centromeric region. SMN1 and SMN2 are ... Mastroeni D, McKee A, Grover A, Rogers J, Coleman PD (August 2009). "Epigenetic differences in cortical neurons from a pair of ... some experiments have been performed on human cells as well as in human drug trials (see table below). There are inherent risks ... Human trials with all of the below HDAC inhibitors are extremely variable and often impacted by the patient's exact SMA subtype ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 21). ... "TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired ... Transmembrane protease, serine 2 is an enzyme that in humans is encoded by the TMPRSS2 gene. It belongs to the TMPRSS family of ... Teng DH, Chen Y, Lian L, Ha PC, Tavtigian SV, Wong AK (June 2001). "Mutation analyses of 268 candidate genes in human tumor ...
Genes on human chromosome 7, All stub articles, Human chromosome 7 gene stubs). ... a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the ... "Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers". Proceedings of the National ... Stromal antigen 3 is a protein that in humans is encoded by the STAG3 gene. STAG3 protein is a component of a cohesin complex ...
The SLC25A46 gene is located on the q arm of chromosome 5 in position 22.1 and spans 27,039 base pairs. The gene produces a ... Genes on human chromosome 5, Wikipedia articles incorporating text from the United States National Library of Medicine, Solute ... Solute carrier family 25 member 46 is a protein that in humans is encoded by the SLC25A46 gene. This protein is a member of the ... Human) - SLC25A46 gene & protein". www.uniprot.org. Retrieved 2018-08-16. This article incorporates text available under the CC ...
... is a gene located in the human genome on the short arm of chromosome 1 at p32.2, between 53,679,771 base pairs and ... The loss of the short arm of chromosome 1, the part of chromosome 1 that C1orf123 is located on, cause and parathyroid gland ... Gene Neighborhood The following genes are close to CZIB on chromosome 1 -LRP8:This gene encodes a member of the low density ... For the most part, "C1orf123" is expressed in relatively average amounts in the human body with the exception of CD34+ and CD56 ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 10, Human proteins). ... The NDUFB8 gene is located on the q arm of chromosome 10 in position 24.31 and is 6,194 base pairs long. The NDUFB8 protein ... "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome ... "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. "Mouse PubMed ...
Humans have 23 pairs of chromosomes, while chimpanzees, gorillas and orangutans have 24. Human chromosome 2 is a fusion of two ... human to human) was set to be 1. The ID between humans and gorillas was determined to be 1.09, that between humans and ... Human evolutionary genetics studies how one human genome differs from another human genome, the evolutionary past that gave ... These findings hint at the seemingly important role of human-specific insertions in the recent evolution of humans. Human ...
The human RAD21 (hRAD21) gene is located on the long (q) arm of chromosome 8 at position 24.11 (8q24.11). In 1997, RAD21 was ... The major role of Rad21L cohesin complex is in homologue pairing and synapsis, not in sister chromatid cohesion, whereas Rec8 ... Articles with short description, Short description is different from Wikidata, Genes on human chromosome 8, Wikipedia articles ... June 2012). "RAD21 mutations cause a human cohesinopathy". American Journal of Human Genetics. 90 (6): 1014-27. doi:10.1016/j. ...
"Homologous expressed genes in the human sex chromosome pairing region". Nature. 317 (6039): 739-41. Bibcode:1985Natur.317..739B ... CD99+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD99 genome location and ... a gene shared by the human X and Y chromosomes". Cold Spring Harb. Symp. Quant. Biol. 51 (1): 205-12. doi:10.1101/SQB.1986.051. ... Genes on human chromosome X, Clusters of differentiation). ... Unusually for a gene present on the X chromosome, the CD99 gene ...
Y-chromosome haplotypes and implications for human history in the Pacific". Human Mutation. 17 (4): 271-80. doi:10.1002/humu.23 ... "Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian- and Papuan-speaking ... "Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea". The American Journal of ... and East Indonesia by human Y-chromosome DNA haplogroups based on relevant studies. Oceania Languages of Oceania Demographics ...
"International Human Genome Sequencing Consortium Announces "Working Draft" of Human Genome". National Human Genome Research ... Human Genome Sequencing Consortium (2004). "Finishing the euchromatic sequence of the human genome". Nature. 431 (7011): 931- ... The institute's research in human genetics focuses on the characterisation of human genetic variation in health and disease. ... Explores human gene function by studying the impact of genome variation on cell biology. Large-scale systematic screens are ...
The chapters are numbered for the pairs of human chromosomes, one pair being the X and Y sex chromosomes, so the numbering goes ... The book devotes one chapter to each pair of human chromosomes. Since one (unnumbered) chapter is required to discuss the sex ... the chapters matching the 23 pairs of human chromosomes, and notes that Genome is the third of Ridley's books that "tries to ... Ridley concludes that the Human Genome Project is largely based on the inaccurate belief that there is one single human genome ...
When multiple chromosomes are involved in chromothripsis, fragments of both chromosomes are joined together by paired end ... using genome-wide paired-end sequencing and SNP array analysis have found similar patterns of chromothripsis in various human ... Cells with defective chromosome segregation will form micronuclei which contain whole chromosomes or fragments of chromosomes. ... Through paired end sequencing, 55 chromosomal rearrangements were found in the long arm of chromosome 8 and a significant ...
In humans, both genes are located on chromosome 2 in position 2p12. The CD8 co-receptor is predominantly expressed on the ... To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8- ... Genes on human chromosome 2, Clusters of differentiation, Immunology, T cells). ... PDB: 1cd8​; Leahy DJ, Axel R, Hendrickson WA (March 1992). "Crystal structure of a soluble form of the human T cell coreceptor ...