Jumping library
... human NotI jumping library from a lymphoblastoid cell line and a human chromosome 3-specific NotI jumping library from a human ... About 0.03%-0.54% of fragments represent chimeric pairs, which are pairs of end-reads that are mapped to two different ... In 1987, a human chromosome jumping library was constructed to clone the cystic fibrosis gene. Cystic fibrosis is an autosomal ... Met oncogene was a marker tightly linked to the cystic fibrosis gene on human chromosome 7, and the library was screened for a ...
Repeated sequence (DNA)
Miga KH (September 2015). "Completing the human genome: the progress and challenge of satellite DNA assembly". Chromosome ... Short interspersed nuclear elements (SINEs) are typically 100-300 base pairs and no longer than 600 base pairs. Long-terminal ... X chromosomes are less effected than males who only have on X chromosome and one Y chromosome because the second X chromosome ... Miga KH (September 2015). "Completing the human genome: the progress and challenge of satellite DNA assembly". Chromosome ...
C11orf52
Articles with short description, Short description matches Wikidata, Genes on human chromosome 11, Human proteins). ... The mRNA sequence is 1,140 base pairs long. There is an upstream stop codon located at nucleotides 65 - 67. The 23rd amino acid ... C11orf52 spans 155658 base pairs and is orientated on the positive strand. Gene C11orf52 has a molecular weight of 14kDa and is ... "Human hg19 chr11:111,789,601-111,797,595 UCSC Genome Browser v384". "AceView: Gene:HSPB2andC11orf52, a comprehensive annotation ...
FAM49A
... is located on human chromosome 2, at 2p24.3. It has 1512 base pairs in the reference sequence mRNA transcript. The ... Genes on human chromosome 2, All stub articles, Human chromosome 2 gene stubs). ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... Family with sequence similarity 49, member A, also known as FAM49A, is a protein which in humans is encoded by the FAM49A gene ...
HIST3H3
Genes on human chromosome 1, All stub articles, Human chromosome 1 gene stubs). ... Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core ... Albig W, Ebentheuer J, Klobeck G, Kunz J, Doenecke D (Dec 1996). "A solitary human H3 histone gene on chromosome 1". Hum Genet ... Histone H3.1t is a protein that in humans is encoded by the HIST3H3 gene. Histones are basic nuclear proteins that are ...
Chromatin structure remodeling (RSC) complex
The breaks can lead to mutations that reposition a chromosome and can even lead to the entire loss of a chromosome. The ... These loops can consist of hundreds of base pairs, but the length depends on how tightly the DNA is wound, as well as how much ... Due to research done using BLAST (biotechnology), it is believed that the yeast RSC complex is even more similar to the human ... SWI/SNF is recruited first, prior to two homologous chromosomes bind, and then RSC is recruited to help complete the repair. A ...
MKS1
Genes on human chromosome 17, Genes mutated in mice). ... 2007). "A disease causing deletion of 29 base pairs in intron ... Meckel syndrome, type 1 also known as MKS1 is a protein that in humans is encoded by the MKS1 gene. The MKS1 protein along with ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
Human evolution
two ancestral ape chromosomes fused to give rise to human chromosome 2 Johanson, Donald; Wong, Kate (2010). Lucy's Legacy: The ... These changes taken together have been interpreted as a result of an increased emphasis on pair bonding as a possible solution ... origin of religions Evolutionary psychology Human behavioral ecology Human origins Human vestigiality List of human evolution ... October 15, 1991). "Origin of human chromosome 2: An ancestral telomere-telomere fusion". Proc. Natl. Acad. Sci. U.S.A. 88 (20 ...
Chromosome 17
... is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome ... "Chromosome 17: Chromosome summary - Homo sapiens". Ensembl Release 88. 2017-03-29. Retrieved 2017-05-19. "Human chromosome 17: ... Chromosome 17 contains the Homeobox B gene cluster. The following are some of the gene count estimates of human chromosome 17. ... "Chromosome 17". Genetics Home Reference. Archived from the original on 2007-06-30. Retrieved 2017-05-06. "Chromosome 17". Human ...
FANCD2
Articles with short description, Short description matches Wikidata, Genes on human chromosome 3, Human proteins). ... FANCD2 mutant mice exhibit chromosome mis-pairing during the pachytene stage of meiosis and germ cell loss. Activated FANCD2 ... November 1995). "Microcell mediated chromosome transfer maps the Fanconi anaemia group D gene to chromosome 3p". Nature ... Humans with a FANCD2 deficiency have increased acute myeloid leukemia, and squamous cell carcinomas (head and neck squamous ...
DAZ3
Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 ... Yen PH, Chai NN, Salido EC (1997). "The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly ... Fox MS, Reijo Pera RA (2002). "Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic ... 1996). "The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified ...
TMEM50A
The TMEM50A gene is located on chromosome 1 p36.11 in the human (homo sapiens) genome. Its mRNA sequence is 2284 base pairs in ... CS1: long volume value, Articles with short description, Short description matches Wikidata, Genes on human chromosome 1). ... 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs ... Transmembrane protein 50A is a protein that in humans is encoded by the TMEM50A gene. This gene is located in the RH gene locus ...
WDR90
In the human genome, WDR90 spans from base pairs 649363 to 667833, and has an mRNA sequence that is 5,250 nucleotides in length ... This human gene is located in the positive DNA strand on chromosome 16 at the position 16p13.3. Flanking sequences on the ... The de novo protein structure of WDR90 in humans is predicted to possess beta sheets, beta turns, and random coils. The human ... WD repeat-containing protein 90 is a protein that, in humans, is encoded by the WDR90 gene (16p13.3). This human protein is ...
EVI5L
Chromosome-centric Human Proteome Project Chromosome-centric Human Proteome Project, EVI5L (Homo sapiens) Pan X, Eathiraj S, ... starting at 7,830,275 base pairs and ending at 7,864,976 base pairs. It is encoded for on the plus strand. It is located near ... "Identification of recognition sites for myc/max/mxd network proteins by a whole human chromosome 19 selection strategy". ... EVI5L (Ecotropic Viral Integration Site 5-Like) is a protein that in humans is encoded by the EVI5L gene. EVI5L is a member of ...
PIF1 5'-to-3' DNA helicase
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 15, Wikipedia articles ... "Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNA". J. Biol. Chem. 288 (22): 16185-95. ... PIF1 5'-to-3' DNA helicase is a protein that in humans is encoded by the PIF1 gene. This gene encodes a DNA-dependent adenosine ... Gagou ME, Ganesh A, Thompson R, Phear G, Sanders C, Meuth M (July 2011). "Suppression of apoptosis by PIF1 helicase in human ...
TBX1
The TBX1 gene is located on the long (q) arm of chromosome 22 at position 11.21, from base pair 18,118,779 to base pair ... CS1: long volume value, Articles with short description, Short description matches Wikidata, Genes on human chromosome 22, ... Packham EA, Brook JD (April 2003). "T-box genes in human disorders". Human Molecular Genetics. 12. 12 Spec No 1 (Spec No 1): ... Human Mutation. 34 (9): 1250-1259. doi:10.1002/humu.22354. PMC 3746749. PMID 23661601. TBX1+protein,+human at the U.S. National ...
PAX1
Paired box protein Pax-1 is a protein that in humans is encoded by the PAX1 gene. This gene is a member of the paired box (PAX ... v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome 20, Wikipedia ... 1989). "Conservation of the paired domain in metazoans and its structure in three isolated human genes". EMBO J. 8 (4): 1183-90 ... 2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865-71. Bibcode:2001Natur.414.. ...
HIPK2
... human) in the human genome. In mice, HIPK2 was discovered to be on Chromosome 6. There is evidence to suggest that HIPKs ... The HIPK2 gene contains 13 exons and 13 introns within the entire 59.1 Kilo-base pair sequence. Along with the other HIPKs, it ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 7). ... The human sequence shares a close similarity to a sequence from the genome of Caenorhabditis elegans. HIPKs also share a close ...
Interleukin 24
The gene for IL-24 is located on chromosome 1 in humans. The structure of IL-24 has been found through crystallization by ... The cDNA of IL-24 is 1,718 base pairs in length and encodes a protein of 206 amino acid with a predicted molecular size of ˜24 ... It is located on chromosome 1q32-33 in humans along with several other IL-10 cytokine family gene members. IL-24 encompasses ... In humans, this protein is encoded by the IL24 gene. IL-24 is a cytokine belonging to the IL-10 family of cytokines that ...
MiR-203
In humans, this region is conserved and located intergenically in 14q32. Sonkoly et al. found that miR-203 displays a highly ... The guide strand of the miRNA is then loaded into RNA-induced silencing complex (RISC) and is then able to pair with its target ... In mice, miR-203 is located in chromosome 12, within a fragile 7-Mb region that is lost is some hematopoietic malignancies. ... demonstrated that in humans, miR-203 expression is first detectable at 17 weeks gestation in the suprabasal layers of epidermis ...
Basic leucine zipper and W2 domain-containing protein 2
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 7, All stub articles, ... The gene spans 60,389 base pairs, at coordinates 16,583,248 - 16,804,999. There are 12 exons. There are two known isoforms of ... The human BZW2 protein has an overall charge of -3 which can go down to -9 in orthologs. There are no significant charge ... The amino acid composition of BZW2 has a higher amount of lysines and a lower amount of prolines in humans but a higher ...
PET117
The PET117 gene is located on the p arm of chromosome 20 in position 11.23 and spans 5,314 base pairs. The gene produces a 9.2 ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 20, Wikipedia articles ... PET117 homolog is a protein that in humans is encoded by the PET117 gene. Localized to mitochondria, this protein is a ... incorporating text from the United States National Library of Medicine, All stub articles, Human chromosome 20 gene stubs). ...
Artificial gene synthesis
It required designing and creating 273,871 base pairs of DNA - fewer than the 316,667 pairs in the original chromosome. In ... August 1981). "Total synthesis of a human leukocyte interferon gene". Nature. 292 (5825): 756-62. Bibcode:1981Natur.292..756E. ... In addition, artificial gene synthesis could in the future make use of novel nucleobase pairs (unnatural base pairs). ... The first synthetic yeast chromosome was synthesised in 2014, and entire functional bacterial chromosomes have also been ...
Biotinidase
The BTD gene is located on the short (p) arm of chromosome 3 at position 25, from base pair 15,618,326 to base pair 15,662,328 ... Human genes, Protein pages needing a picture, Genes on human chromosome 3, Wikipedia articles incorporating text from the ... The human body cannot produce biotin, but it can obtain it from the diet, internal recycling and at some extent from intestinal ... Biotinidase (EC 3.5.1.12, amidohydrolase biotinidase, BTD), also known as biotinase, is an enzyme that in humans is encoded by ...
GTF2H2
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 5, Wikipedia articles ... It is reported to be different by either two or four base pairs; however, no sequence data is currently available for the ... General transcription factor IIH subunit 2 is a protein that in humans is encoded by the GTF2H2 gene. This gene is part of a ... Drapkin R, Le Roy G, Cho H, Akoulitchev S, Reinberg D (1996). "Human cyclin-dependent kinase-activating kinase exists in three ...
List of MeSH codes (A11)
... human, pair 2 MeSH A11.284.187.520.300.235.250 - chromosomes, human, pair 3 MeSH A11.284.187.520.300.280 - chromosomes, human, ... human, pair 4 MeSH A11.284.187.520.300.280.290 - chromosomes, human, pair 5 MeSH A11.284.187.520.300.325 - chromosomes, human, ... human, pair 14 MeSH A11.284.187.520.300.370.385 - chromosomes, human, pair 15 MeSH A11.284.187.520.300.415 - chromosomes, human ... human, pair 17 MeSH A11.284.187.520.300.415.430 - chromosomes, human, pair 18 MeSH A11.284.187.520.300.460 - chromosomes, human ...
SOX3
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome X, Wikipedia articles ... Schepers GE, Teasdale RD, Koopman P (August 2002). "Twenty pairs of sox: extent, homology, and nomenclature of the mouse and ... Transcription factor SOX-3 is a protein that in humans is encoded by the SOX3 gene. This gene encodes a member of the SOX (SRY- ... SOX3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ...
UQCC2
Genes on human chromosome 6, Wikipedia articles incorporating text from the United States National Library of Medicine, Human ... The UQCC2 gene is located on the p arm of chromosome 6 in position 21.31 and spans 14,990 base pairs. The gene produces a 14.9 ... Ubiquinol-cytochrome c reductase complex assembly factor 2 is a protein that in humans is encoded by the UQCC2 gene. Located in ... "UQCC2 - Ubiquinol-cytochrome-c reductase complex assembly factor 2 precursor - Homo sapiens (Human) - UQCC2 gene & protein". ...
QRICH1
... is located on chromosome 3p21.31 and contains 11 exons. The genomic sequence begins at base pair 49,057,531 and ends at ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 3, Wikipedia articles ... QRICH1, also known as Glutamine-rich protein 1, is a protein that in humans is encoded by the QRICH1 gene. One notable feature ... It is expressed ubiquitously throughout the human body, although EST Profile data reveal that QRICH1 is expressed particularly ...
Chromosome 16
... is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome ... "Chromosome 16: Chromosome summary - Homo sapiens". Ensembl Release 88. 2017-03-29. Retrieved 2017-05-19. "Human chromosome 16: ... Gilbert F (1999). "Disease genes and chromosomes: disease maps of the human genome. Chromosome 16". Genet Test. 3 (2): 243-54. ... 16p13.3 Wikimedia Commons has media related to Human chromosome 16. National Institutes of Health. "Chromosome 16". Genetics ...