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*  Homologous chromosome
Humans have a total of 46 chromosomes, but there are only 22 pairs of homologous autosomal chromosomes. The additional 23rd ... pair is the sex chromosomes, X and Y. If this pair is made up of an X and Y chromosome, then the pair of chromosomes is not ... So humans have two homologous chromosome sets in each cell, meaning humans are diploid organisms. Homologous chromosomes are ... Therefore, when two chromosomes of the exact structure exist, they are able to pair together to form homologous chromosomes. ...
*  Chromosome 6 (human)
The human leukocyte antigen lies on chromosome 6, with the exception of the gene for β2-microglobulin (which is located on ... See also: Category:Genes on human chromosome 6. The following is a partial list of genes on human chromosome 6. For complete ... The following are some of the genes located on p-arm (short arm) of human chromosome 6: ADTRP: encoding protein Androgen- ... October 2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805-11. doi:10.1038/nature02055. PMID ...
*  Wellcome Sanger Institute
The Institute was engaged in collaborations to sequence 8 of the 23 human pairs of chromosomes (1, 6, 9, 10, 13, 20, 22, and X ... "International Human Genome Sequencing Consortium Announces "Working Draft" of Human Genome". National Human Genome Research ... Human Genome Sequencing Consortium (2004). "Finishing the euchromatic sequence of the human genome". Nature. 431 (7011): 931- ... The Institute's research in human genetics focuses on the characterisation of human genetic variation in health and disease. ...
*  Cyclin-dependent kinase 6
The CDK6 gene is located on chromosome 7 in humans. The gene spans 231,706 base pairs and encodes a 326 amino acid protein with ... CDK6 human gene location in the UCSC Genome Browser. CDK6 human gene details in the UCSC Genome Browser. Molecular and Cellular ... Cheng A, Kaldis P, Solomon MJ (Nov 2000). "Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C ... These features are reached through upregulation of CDK6 due to chromosome alterations or epigenetic dysregulations. ...
*  Chromosome 5 (human)
Chromosome 5 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 5 ... A ring chromosome occurs when both ends of a broken chromosome are reunited. G-banding ideograms of human chromosome 5 "Human ... See also: Category:Genes on human chromosome 5. The following is a partial list of genes on human chromosome 5. For complete ... Chromosome 5 is the 5th largest human chromosome, yet has one of the lowest gene densities. This is partially explained by ...
*  PTCHD4
Human PTCHD4 is located on the negative strand of chromosome 6, at 6p12.3. From there, it covers 190,350 base pairs, which ... Check date values in: ,access-date= (help) "The Human Protein Atlas". The Human Protein Atlas. Retrieved 2015. Check date ... "The Human Gene Compendium". Gene Cards. Retrieved 2015. Check date values in: ,access-date= (help) "National Center for ... Sequenced distant orthologs of human PTCHD4 have been found as far back in evolution as mold, which shows a conservation of 16 ...
*  Dictyostelid
For comparison, the diploid human genome has 20,000-25,000 genes (represented twice) on 23 chromosome pairs. There is a high ... Dictyostelium shares many molecular features with macrophages, the human host of Legionella. The cytoskeletal composition of D ... Tandem repeats of trinucleotides are abundant in Dictyostelium, which in humans cause Trinucleotide repeat disorders. Sexual ... 6 (7): e1001013. doi:10.1371/journal.pgen.1001013. PMC 2895654 . PMID 20617172. O'Day DH, Keszei A (May 2012). "Signalling and ...
*  TP53-inducible glycolysis and apoptosis regulator
In humans the TIGAR gene, known as C12orf5, is found on chromosome 12p13-3, and consists of 6 exons. The C12orf5 mRNA is 8237 ... base pairs in length. Jen and Cheung first discovered the c12orf5 gene whilst using computer based searches to find novel p53- ... "NCBI Summary C12orf5 chromosome 12 open reading frame 5". Madan E, Gogna R, Kuppusamy P, Bhatt M, Pati U, Mahdi AA (July 2012 ... The second is found just prior to the first exon, binds p53 with low affinity, and is conserved between mice and humans. TIGAR ...
*  FKBP6
... is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice ... Mutations in this gene have been associated with male infertility in humans. FKBP6 is deleted in Williams syndrome, however ... 2003). "Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis". Science. 300 (5623): 1291-5. ... PDB: 3B7X​; "RCSB Protein Data Bank - Structure Summary for 3B7X - Crystal structure of human FK506-Binding Protein 6". ...
*  Chromosome 11 (human)
Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome ... See also: Category:Genes on human chromosome 11. The following is a partial list of genes on human chromosome 11. For complete ... At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome ... "Chromosome 11". Genetics Home Reference. Retrieved 2017-05-06. "Chromosome 11". Human Genome Project Information Archive 1990- ...
*  PAX7
Schäfer BW, Mattei MG (July 1993). "The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2". Genomics. 17 (1 ... Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. Pax-7 plays a role in neural crest ... Pilz AJ, Povey S, Gruss P, Abbott CM (March 1993). "Mapping of the human homologs of the murine paired-box-containing genes". ... PAX7 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) PAX7 human gene location in the UCSC ...
*  Chorionic gonadotropin beta
Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I (October 1983). "The beta subunit of human chorionic ... Choriogonadotropin subunit beta (CG-beta) also known as chorionic gonadotrophin chain beta is a protein that in humans is ... GRCh38: Ensembl release 89: ENSG00000104827 - Ensembl, May 2017 "Human PubMed Reference:". "Entrez Gene: chorionic gonadotropin ... The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and ...
*  CGB7
1984). "The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19". Hum. Genet. 67 (2): 174-7. ... Choriogonadotropin subunit beta is a protein that in humans is encoded by the CGB7 gene. This gene is a member of the ... Fiddes JC, Goodman HM (1980). "The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by ... Morgan FJ, Birken S, Canfield RE (1975). "The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta ...
*  BHLHE41
... was mapped to human chromosome 12: 26,120,026-26-125-127 reverse strand and has a total length of 5,101 base pairs. The ... "Human PubMed Reference:". "Mouse PubMed Reference:". "BHLHE41 basic helix-loop-helix family, member e41 [ Homo sapiens (human ... Human BHLHE41 genome location and BHLHE41 gene details page in the UCSC Genome Browser. This article incorporates text from the ... Kurien PA, Chong SY, Ptáček LJ, Fu YH (October 2013). "Sick and tired: how molecular regulators of human sleep schedules and ...
*  ENOX2
The human ENOX2 gene is located on the long (q) arm of the X chromosome in humans, at region 2 band 6 sub band 1, from base ... pair 130,622,330 to 130,903,317 (build GRCh38.p7) (map). The gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, ... ENOX2 is a gene located on the long arm of the X chromosome in humans. The gene encodes the protein Ecto-NOX disulfide-thiol ... 2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325-37. doi:10.1038/nature03440. PMC 2665286 . PMID ...
*  Marta Mirazón Lahr
"Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian- and Papuan-speaking ... She and Robert Foley were the first to propose a 'southern route' for humans out of Africa, and for human diversity to be the ... Lahr's research is in human evolution, and ranges across human and hominin morphology, prehistory and genetics. Her early work ... Lahr, M. M. & Foley, R. (1998). "Towards a theory of modern human origins: Geography, demography, and diversity in recent human ...
*  Laboratory mouse
This was only the second mammalian genome to be sequenced after humans. The haploid genome is about three billion base pairs ... long (3,000 Mb distributed over 20 chromosomes), therefore equal to the size of the human genome. Estimating the number of ... "Human assembly and gene annotation". Ensembl. Retrieved 29 July 2013. "JAX Mice Database - 002983 MRL.CBAJms-Fas/J". Jaxmice. ... compared to an estimated 20,774 in humans. Various mutant strains of mice have been created by a number of methods. A small ...
*  Nocardia farcinica
The chromosome encodes 5,674 potential protein-coding open reading frames. This genome may have undergone numerous gene ... Strains of this species have been isolated from human brain abscesses. N. farcinica contains a 6 million base pair genome with ... Holm, P (July 1975). "Seven cases of human nocardiosis caused by Nocardia farcinica". Sabouraudia. 13 (2): 161-9. doi:10.1080/ ...
*  Artificial gene synthesis
It required designing and creating 273,871 base pairs of DNA - fewer than the 316,667 pairs in the original chromosome. In ... The procedure involved replacing the genes in the original chromosome with synthetic versions and the finished human made ... The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs ... Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, ...
*  PAX1
... a member of the paired box-containing class of developmental control genes, is mapped to human chromosome 20p11.2 by in situ ... Paired box protein Pax-1 is a protein that in humans is encoded by the PAX1 gene. This gene is a member of the paired box (PAX ... 1989). "Conservation of the paired domain in metazoans and its structure in three isolated human genes". EMBO J. 8 (4): 1183-90 ... 2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865-71. doi:10.1038/414865a. ...
*  C6orf201
In humans, the gene is 51,558 base pairs long. The transcript that produces the longest protein of 140 amino acids is ... "GeneCards: The Human Gene Compendium". Retrieved 8 February 2015. "Homo sapiens chromosome 6 open reading frame 201 (C6orf201) ... "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. "EST ... is a protein that in humans is encoded by the C6orf201 gene. In humans this gene encodes for a nuclear protein that is ...
*  ANKRD24
The gene is located on chromosome 19 at p13.3 on the forward strand. The gene is 4041 base pairs in length and contains 29 ... ANKRD24 has no human paralogs. Orthologous proteins are found in other organisms. The following table represents some of the ... Ankyrin repeat domain-containing protein 24 is a protein in humans that is coded for by the ANKRD24 gene. The gene is also ... The protein's function in humans is currently unknown. ANKRD24 is in the protein family that contains ankyrin-repeat domains. ...
*  C15orf52
Chromosome 15 open reading frame 52 is a protein which in humans is encoded by the C15orf52 gene. This protein has a function ... The linear mRNA is 5344 base pairs long. The mRNA contains a short 5' untranslated region of 15 base pairs and a long 3' ... C15orf52 is a gene located on the reverse strand of chromosome 15 in the species Homo sapiens at locus 15q15.1. The gene is ... "A human interactome in three quantitative dimensions organized by stoichiometries and abundances." Cell 163.3 (2015): 712-723. ...
*  Aldolase B
In humans, aldolase B is encoded by the ALDOB gene located on chromosome 9. The gene is 14,500 base pairs long and contains 9 ... 1988). "Human aldolase B gene: characterization of the genomic aldolase B gene and analysis of sequences required for multiple ... Ali M, Sebastio G, Cox TM (1994). "Identification of a novel mutation (Leu 256→Pro) in the human aldolase B gene associated ... Aldolase B at the US National Library of Medicine Medical Subject Headings (MeSH) Human ALDOB genome location and ALDOB gene ...
*  C1orf74
The gene C1orf74 is a protein-encoding gene on chromosome 1 in humans. It is also known as URLC4 in humans. The locus of this ... C1orf74 is 2229 base pairs long. The gene contains two exons. C1orf74 is downstream of the gene interferon regulatory factor 6 ... "C1orf74 chromosome 1 open reading frame 74 [Homo sapiens (human)]". NCBI Gene. NCBI. Retrieved 8 May 2015. "Homo sapiens ... May 2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315-21. doi:10.1038/ ...
*  TENM3
Odz1 to Mouse Chromosome 11; and ODZ3 to Human Chromosome Xq25". Genomics. 58 (1): 102-3. doi:10.1006/geno.1999.5798. PMID ... Levine A, Bashan-Ahrend A, Budai-Hadrian O, Gartenberg D, Menasherow S, Wides R (May 1994). "odd Oz: A novel Drosophila pair ... Odz1to Mouse Chromosome 11; and ODZ3 to Human Chromosome Xq25". Genomics. 58 (1): 102-103. doi:10.1006/geno.1999.5798. PMID ... Ben-Zur, T.; Feige, E.; Motro, B.; Wides, R. (2000). "The Mammalian Odz Gene Family: Homologs of a Drosophila Pair-Rule Gene ...
*  Cornish Rex
In humans LPAR6 mutations result in a wooly hair phenotype. The Cornish Rex is a genetic mutation that originated from a litter ... A gene on chromosome A1, the lysophosphatidic acid receptor 6 (LPAR6), was identified to have a 4 base pair deletion. This ... PLOS One, 2013 Jun 27;8(6) Observer Sunday supplement science column 'A New Look In Cats' 31 January 1965 pp4-5. ...