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*  Homologous chromosome
Humans have a total of 46 chromosomes, but there are only 22 pairs of homologous autosomal chromosomes. The additional 23rd ... pair is the sex chromosomes, X and Y. If this pair is made up of an X and Y chromosome, then the pair of chromosomes is not ... So humans have two homologous chromosome sets in each cell, meaning humans are diploid organisms. Homologous chromosomes are ... Therefore, when two chromosomes of the exact structure exist, they are able to pair together to form homologous chromosomes. ...
*  Chromosome 21 (human)
... working on the Human Genome Project announced that they had determined the sequence of base pairs that make up this chromosome ... Gilbert F (1997). "Disease genes and chromosomes: disease maps of the human genome. Chromosome 21". Genet Test. 1 (4): 301-6. ... after chromosome 22. The following are some of the gene count estimates of human chromosome 21. Because researchers use ... The following is a partial list of genes on human chromosome 21. For complete list, see the link in the infobox on the right. ...
*  Radiation hybrid mapping
The RH procedure was used to map 14 DNA probes from a region of human chromosome 21 spanning 20 megabase pairs. Deloukas, Panos ... If two given DNA markers are far apart on the initial chromosome, then it is likely that they will appear in distinct fragments ... First of all, desired chromosomes are broken into several segments with X-rays, after which they are implanted in rodent cells ... Radiation hybrid mapping (also known as RH mapping) is a technique for mapping mammalian chromosomes. Radiation hybrid mapping ...
*  Robertsonian translocation
In humans, Robertsonian translocations generally occur in the five acrocentric chromosome pairs, namely 13, 14, 15, 21 and 22. ... or non-homologous chromosomes (i.e. two different chromosomes, not belonging to a homologous pair). A feature of chromosomes ... This type of translocation is cytologically visible, and can reduce chromosome number (from 23 to 22 pairs, in humans) if the ... The nonrandom participation of human acrocentric chromosomes in Robertsonian translocations. Annals of Human Genetics 1989;53: ...
*  Rhesus macaque
The PRAME family has 26 members on human chromosome 1. In the macaque, it has eight, and has been very simple and stable for ... but do have peaceful relationships with the offspring of their consort pairs. Manson and Parry found that free-ranging rhesus ... coming to rely on handouts or refuse from humans. They adapt well to human presence, and form larger troops in human-dominated ... So, macaque, chimpanzee, and human chromosomes are mosaics of each other. Surprisingly, some normal gene sequences in healthy ...
*  Chromosome 22 (human)
Chromosome 22 is one of the 23 pairs of chromosomes in human cells. Humans normally have two copies of chromosome 22 in each ... Chromosome 22 was the first human chromosome to be fully sequenced. Chromosome 22 was originally identified as the smallest ... Chromosome 22 is the second smallest human chromosome (chromosome 21 being smaller), spanning about 49 million DNA base pairs ... See also: Category:Genes on human chromosome 22. The following is a partial list of genes on human chromosome 22. For complete ...
*  C21orf62
... in humans, is encoded by the C21orf62 gene. C21orf62 is found on human chromosome 21, and it is thought to be expressed in ... The C21orf62 gene is 4132 base pairs in length and contains five exons. The mRNA sequence of C21orf62 in humans has one known ... C21orf62 in humans has higher cysteine and lower valine concentrations than expected compared to other human proteins. This ... The C21orf62 protein in humans has a sequence that is 219 amino acids in length. The primary sequence of C21orf62 in humans has ...
*  RUFY2
The human RUFY2 gene is located on the long (q) arm of chromosome 10 at region 21 band 3, from base pair 70,100,864 to base ... There are 18 predicted exons in the human gene with 13 alternative transcripts. 8,180 base pairs upstream of RUFY2 is the ... RUN and FYVE domain containing 2 (RUFY2) is a protein that in humans is encoded by the RUFY2 gene. The RUFY2 gene is named for ... pair 70,167,051 on the reverse strand (Build GRCh37/hg19) (map). The gene produces a 2,080 base pair mRNA. ...
*  Nucleic acid
... to large chromosomes (human chromosome 1 is a single molecule that contains 247 million base pairs). In most cases, naturally ... May 2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315-21. Bibcode:2006Natur. ... International Human Genome Sequencing Consortium (2001). "Initial sequencing and analysis of the human genome" (PDF). Nature. ... Within cells DNA is organized into long structures called chromosomes. During cell division these chromosomes are duplicated in ...
*  Human genetic variation
Chromosome abnormalities are detected in 1 of 160 live human births. Apart from sex chromosome disorders, most cases of ... The human nucleotide diversity is estimated to be 0.1% to 0.4% of base pairs. A difference of 1 in 1,000 amounts to ... According to a 2000 study of Y-chromosome sequence variation, human Y-chromosomes trace ancestry to Africa, and the descendants ... No two humans are genetically identical. On average, in DNA sequence, each human is 99.5% similar to any other human. Even ...
*  Chromosome abnormality
... or has more than two chromosomes of a pair (trisomy, tetrasomy, etc.). In humans, an example of a condition caused by a ... It can be from an atypical number of chromosomes or a structural abnormality in one or more chromosomes. Chromosome mutation ... on chromosome 17. Translocations: A portion of one chromosome is transferred to another chromosome. There are two main types of ... Known disorders in humans include Wolf-Hirschhorn syndrome, which is caused by partial deletion of the short arm of chromosome ...
*  Diploid triploid mosaic
A regular human carries 23 pairs of chromosomes in his or her cells. Cells containing two pairs of chromosomes are known as ... or a total of 69 chromosomes. Triploidy is distinct from trisomy, in which only one chromosome exists in three pairs. A well- ... Individuals with diploid-triploid syndrome have some cells with three copies of each chromosome for a total of 69 chromosomes ( ... and some cells with the usual 2 copies of each chromosome for a total of 46 chromosomes (called diploid cells). Having two or ...
*  Metalloexopeptidase
The former resides in Chromosome 15 and is made up of 951,392 base pairs (bases) while the latter resides in Chromosome 11 and ... Examples of these compounds in the human genome include AGBL1 and AGBL2, known also as ATP/GTP Binding Protein-Like 1 and 2, ... Retrieved 2016-05-21. Metalloexopeptidase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... Retrieved 2016-05-21. "AGBL1". www.genecards.org. Retrieved 2016-05-21. "AGBL2". www.genecards.org. ...
*  PAX7
Schäfer BW, Mattei MG (July 1993). "The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2". Genomics. 17 (1 ... Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. Pax-7 plays a role in neural crest ... Pilz AJ, Povey S, Gruss P, Abbott CM (March 1993). "Mapping of the human homologs of the murine paired-box-containing genes". ... PAX7 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) PAX7 human gene location in the UCSC ...
*  FAM43A
... is located on chromosome 3 at location 3q29. It encodes a 3182 base pair mRNA which possesses one Pleckstrin homology- ... Protein FAM43A is a protein that is encoded in humans by the FAM43A gene. The acronym means "family with sequence similarity 43 ... "Human PubMed Reference:". "Mouse PubMed Reference:". NCBI entry on FAM43A Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, ... The protein has been predicted to localize in the nucleus, and possesses a cut signal peptide at amino acid 21. The FAM43A gene ...
*  Polysomy
Since canine chromosome 13 is similar to human chromosome 8q, research could provide insight to treatment for prostate cancer ... Polysomy is usually caused by non-disjunction (the failure of a pair of homologous chromosomes to separate) during meiosis, but ... Human Chromosomes. New York: Springer, 2001. Schmid, M., and Indrajit Nanda. Chromosomes Today, Volume 14. Dordrecht: Kluwer ... 2000). "Reciprocal chromosome painting illuminates the history of genome evolution of the domestic cat, dog and human". ...
*  Homologous somatic pairing
Somatic pairing of homologous chromosomes is similar to pre- and early meiotic pairing (see article: Homologous chromosome#In ... anti-pairing' genes (of which 2 and 1 were already known, respectively), many of which have human orthologs. An earlier RNAi ... Metz, Charles W. (1916). "Chromosome studies on the Diptera. II. The paired association of chromosomes in the Diptera, and its ... Fung, Jennifer C.; Marshall, Wallace F.; Dernburg, Abby; Agard, David A.; Sedat, John W. (1998). "Homologous Chromosome Pairing ...
*  Proline-rich protein 21
It is encoded by the PRR21 gene, which is found on human chromosome 2, band 2q37.3. The gene exists in several species, both ... PRR21 consists of 389 amino acids or 1170 base pairs, all found within one exon. Like other proline-rich proteins, it contains ... "Human PubMed Reference:". "GeneCards". "National Center for Biotechnology Information". Williamson MP (January 1994). "The ... Proline-rich protein 21 (PRR21) is a protein of the family of proline-rich proteins. ...
*  FAM227a
It is 2,948 base pairs long, and includes the first 17 exons. The second isoform, NM_001291030.1, is 10,362 base pairs long. It ... Chromosome 22 was chosen based on the results of the data collected from three clinical visits at the Framingham Heart Study. ... FAM227A is a protein that in humans is encoded by FAM227A gene. Current studies have determined the location of this gene to be ... FAM227A is found on chromosome 22 at the location 22q13.1. It is flanked by the gene LOC105373031 on the left and CBY1 on the ...
*  Eukaryotic chromosome fine structure
The repeats are normally a few hundred base pairs in length. These sequences constitute about 13% of the human genome with the ... Eukaryotic chromosome fine structure refers to the structure of sequences for eukaryotic chromosomes. Some fine sequences are ... They may also be involved in fillers for increasing chromosome size to some minimum threshold level necessary for chromosome ... Typical eukaryotic chromosomes contain much more DNA than is classified in the categories above. The DNA may be used as spacing ...
*  NDUFB10
... structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Human Molecular Genetics ... The NDUFB10 gene is located on the p arm of chromosome 16 in position 13.3 and is 2,459 base pairs long. The NDUFB10 protein ... NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 is an enzyme that in humans is encoded by the NDUFB10 gene. NADH ... "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Research. 14 ...
*  OSR1
Katoh M (August 2002). "Molecular cloning and characterization of OSR1 on human chromosome 2p24". International Journal of ... a zinc finger encoding segmentation gene with a novel pair-rule expression pattern". The EMBO Journal. 9 (11): 3795-804. PMC ... In human osteoblast and osteosarcoma cell lines, OSR1 is directly induced by 1,25-dihydroxyvitamin D3. A variant human OSR1 ... Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene. The OSR1 and OSR2 ...
*  Genetic architecture
Down Syndrome is a genetic disorder caused by trisomy of human chromosome 21. The current hypothesis regarding congenital heart ... and this study was among the first to utilize these concepts in a paired fashion to determine information about the underlying ... A study of the human immune system in 2015 uses the same general concepts to identify several loci involved in the development ... A study published in 2006 used phylogeny to compare the genetic architecture of differing human skin color. In this study, ...
*  23andMe
The company is named for the 23 pairs of chromosomes in a normal human cell. Its saliva-based direct-to-consumer genetic ... Papers on various genetic traits by 23andMe scientists were presented at the 2014 American Society of Human Genetics. In 2015, ... On October 21, 2015, 23andMe announced that it would begin marketing carrier tests in the US again. CEO Anne Wojcicki said, " ... Retrieved 2015-10-21. Ubelacker, Sheryl (October 1, 2014). "U.S. company launches genetic health and ancestry info service in ...
*  2012 in science
Phys.) According to genetic studies, modern humans seem to have mated with "at least two groups" of ancient humans: ... such as the male Y chromosome, will become extinct. A new study shows that, although such chromosomes have shrunk and lost ... The Telegraph) America's coastlines are even more vulnerable to sea level rise than previously thought, according to a pair of ... closely mimicking the motion of human leg muscles. (BBC) (J. Neural Eng.) 7 July - Non-human animals including all mammals and ...
*  Promoter (genetics)
"Gene promoters show chromosome-specificity and reveal chromosome territories in humans". BMC Genomics. 14 (278): 278. doi: ... On average, only 3 to 4 of the 6 base pairs in each consensus sequence are found in any given promoter. Few natural promoters ... Furthermore, in humans, promoters show certain structural features characteristic for each chromosome. Core promoter - the ... In humans, DNA methylation occurs at the 5' position of the pyrimidine ring of the cytosine residues within CpG sites to form 5 ...
*  GABA transporter 1
"Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25". Genomics. 29 (1): 302-4. doi:10.1006/ ... "Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter ... GABA transporter 1 (GAT1) also known as sodium- and chloride-dependent GABA transporter 1 is a protein that in humans is ... Nelson H, Mandiyan S, Nelson N (August 1990). "Cloning of the human brain GABA transporter". FEBS Letters. 269 (1): 181-4. doi: ...