The breaks can lead to mutations that reposition a chromosome and can even lead to the entire loss of a chromosome. The ... These loops can consist of hundreds of base pairs, but the length depends on how tightly the DNA is wound, as well as how much ... Due to research done using BLAST (biotechnology), it is believed that the yeast RSC complex is even more similar to the human ... SWI/SNF is recruited first, prior to two homologous chromosomes bind, and then RSC is recruited to help complete the repair. A ...
The MN14-1420 isolate have a vls locus, a specific position on a chromosome, consisting of 24 silent cassettes, a mobile gene ... This organism can infect various vertebrate and invertebrate hosts such as humans and ticks, primarily Ixodes scapularis. ... mayonii genome is about 1.31 megabase pairs (Mbp) with an average 26.9% GC (guanine and cytosine) content. It has a linear ... With a nucleotide similarity of 93.83% in the linear chromosome compared to other known genospecies, B. mayonii can be ...
The Human Splicing Finder is an online database stemming from the Human Genome Project data. The genome database identifies ... An intronic single base-pair substitution destroys an acceptor site, thus activating a cryptic splice site, leading to a 59 ... "Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families". Nature Genetics. ... a potential stem-loop structure which is most likely involved in regulating the alternative splicing of exon10 in chromosome 17 ...
This gene is 2252 base pairs long. CCDC116 has 5 exons and is located on chromosome 22q11.21 on the plus strand. CCDC116 has ... A study was done in 2012 on observing how this gene is expressed in human pancreatic islets and in endocrine pancreatic tumors ... 10 November 2018. "CCDC116". NCBI Gene. "Biology Workbench". SDSC Biology Workbench. "ElDorado". Genomatix. Recurrent gene ...
The SCN1A gene is located on chromosome 2 of humans, and is made up of 26 exons spanning a total length of 6030 nucleotide base ... The promoter has been identified 2.5 kilobase pairs upstream of the transcription start site, and the 5'- untranslated exons ... The SCN1A gene codes for the alpha subunit of the voltage-gated sodium ion channel making it a member of ten paralogous gene ... 1994). "Localization of a putative human brain sodium channel gene (SCN1A) to chromosome band 2q24". Cytogenetics and Cell ...
The human gene CCDC37 is found on chromosome 3 at the band 3q21.3. It extends from base pairs 90,403,731 to 90,429,231, making ... There is only one paralog for CCDC37 found in humans, CCDC38. CCDC38 is located on chromosome 12. The ortholog space of CCDC37 ... Coiled-coil domain-containing 37, also known as FLJ40083, is a protein that in humans is encoded by the CCDC37 gene (3q21.3). ... "CCDC38 coiled-coil domain containing 38 [Homo sapiens (human)] - Gene". Ncbi.nlm.nih.gov. Retrieved 2015-03-07. Dinkel, H. The ...
PAR1 comprises 2.6 Mbp of the short-arm tips of both X and Y chromosomes in humans and great apes (X and Y are 154 Mbp and 62 ... Pairing (synapsis) of the X and Y chromosomes and crossing over (recombination) between their pseudoautosomal regions appear to ... The function of these pseudoautosomal regions is that they allow the X and Y chromosomes to pair and properly segregate during ... between the pseudoautosomal regions of the X and Y chromosomes can disrupt pairing and recombination, and consequently cause ...
It shows 22 homologous autosomal chromosome pairs, both the female (XX) and male (XY) versions of the two sex chromosomes, as ... in humans, these only occur with chromosomes 13, 14, 15, 21, and 22. Rings: A portion of a chromosome has broken off and formed ... or has more than two chromosomes of a pair (trisomy, tetrasomy, etc.). Aneuploidy can be full, involving a whole chromosome ... symbols and abbreviated terms used in the description of human chromosome and chromosome abnormalities. Abbreviations include a ...
Miga KH (September 2015). "Completing the human genome: the progress and challenge of satellite DNA assembly". Chromosome ... Short interspersed nuclear elements (SINEs) are typically 100-300 base pairs and no longer than 600 base pairs. Long-terminal ... X chromosomes are less effected than males who only have on X chromosome and one Y chromosome because the second X chromosome ... Miga KH (September 2015). "Completing the human genome: the progress and challenge of satellite DNA assembly". Chromosome ...
v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 15, Wikipedia articles ... "Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNA". J. Biol. Chem. 288 (22): 16185-95. ... PIF1 5'-to-3' DNA helicase is a protein that in humans is encoded by the PIF1 gene. This gene encodes a DNA-dependent adenosine ... Gagou ME, Ganesh A, Thompson R, Phear G, Sanders C, Meuth M (July 2011). "Suppression of apoptosis by PIF1 helicase in human ...
The COL11A2 gene is located on the short (p) arm of chromosome 6 at position 21.3, from base pair 33,238,446 to base pair ... Collagen alpha-2(XI) chain is a protein that in humans is encoded by the COL11A2 gene. The COL11A2 gene produces one component ... It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a ... Hanson IM, Gorman P, Lui VC, Cheah KS, Solomon E, Trowsdale J (November 1989). "The human alpha 2(XI) collagen gene (COL11A2) ...
Its genome consists of two circular chromosomes, one 2.65 million base pairs long and the other 412,000 base pairs long, as ... Some lines of investigation are focused on the application of D. radiodurans antioxidant systems in human cells to prevent ROS ... They translated the song "It's a Small World" into a series of DNA segments 150 base pairs long, inserted these into the ... It usually repairs breaks in its chromosomes within 12-24 hours by a 2-step process. First, D. radiodurans reconnects some ...
Without histones, unwound DNA in chromosomes would be very long. For example, each human cell has about 1.8 meters of DNA if ... This involves the wrapping of DNA around nucleosomes with approximately 50 base pairs of DNA separating each pair of ... June 2007). "The landscape of histone modifications across 1% of the human genome in five human cell lines". Genome Research. ... is a transcription factor which activates histone gene transcription on chromosomes 1 and 6 of human cells. NPAT is also a ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 14). ... "Homologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51C". Proc. Natl. Acad. Sci. U.S.A. 98 (10): 5538-43. doi ... new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages". Mol. Cell ... "Homologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51C". Proc. Natl. Acad. Sci. U.S.A. 98 (10): 5538-5543. ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 17, Use dmy dates from April ... The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its ... flanking region of human cytokeratin 19 gene in human cholangiocarcinoma cell line". Journal of Hepatology. 35 (4): 504-11. doi ... The type I cytokeratins are clustered in a region of chromosome 17q12-q21. KRT19 is also known as Cyfra 21-1. Due to its high ...
HAR1 is a 106-base pair stretch found on the long arm of chromosome 20 overlapping with part of the RNA genes HAR1F and HAR1R. ... There are 18 base pair mutations different between humans and chimpanzees, far more than expected by its history of ... Human accelerated regions (HARs), first described in August 2006, are a set of 49 segments of the human genome that are ... They are named according to their degree of difference between humans and chimpanzees (HAR1 showing the largest degree of human ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 10, CS1 maint: uses authors ... The SFTPA1 gene is 4505 base pairs in length, and 94% similar to SFTPA2. The structure of SFTPA1 consists of four coding exons ... "An immunohistochemical study of bronchial cells producing surfactant protein A in the developing human fetal lung". Early Human ... Karinch AM, Deiter G, Ballard PL, Floros J (Jun 1998). "Regulation of expression of human SP-A1 and SP-A2 genes in fetal lung ...
... is a segment of the human genome found on the long arm of chromosome 20. It is a human accelerated region. It is located within ... a pair of overlapping long non-coding RNA genes, HAR1A (HAR1F) and HAR1B (HAR1R). HAR1A is expressed in Cajal-Retzius cells, ... The HAR1B gene overlaps HAR1A, and is located on the opposite strand of the chromosome. Its expression in the human brain is ... Scientists Identify Gene Difference Between Humans and Chimps, Scientific American, 17 August 2006 Page for Human accelerated ...
CDKN1C is a tumor suppressor human gene on chromosome 11 (11p15) and belongs to the cip/kip gene family. It encodes a cell ... Sequencing can be helpful in identifying base pair mutations. A study done to assess the phenotypic effects that mutations to ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 11, Cell cycle, Tumor suppressor ... "Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15". Proceedings of the ...
2010). "Derivative chromosome 1 and GLUT1 deficiency syndrome in a sibling pair". Mol Cytogenet. 3 (1): 10. doi:10.1186/1755- ... By the age of 90, the human brain will have experienced a 15% loss of its initial peak weight. Besides brain atrophy, aging has ... Zahr NM, Pfefferbaum A (2017). "Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models". Alcohol ... Harris, Taylor C.; de Rooij, Rijk; Kuhl, Ellen (2018-10-17). "The Shrinking Brain: Cerebral Atrophy Following Traumatic Brain ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 4, CS1 errors: periodical ... The binding of specific nucleotide pairs to the two sites results in synergistic inhibition stronger than additive inhibition. ... "Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed". The ... "Assignment of the gene for phosphoribosylpyrophosphate amidotransferase to the pter leads to q21 region of human chromosome 4 ...
The current size determined for FAM227B is 293,961 base pairs (NCBI). Neighbors of FAM227B on chromosome fifteen include: " ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 15, Articles needing additional ... FAM227B is a protein that in humans is encoded by FAM227B gene. FAM227B stands for family with sequence similarity 227 member B ... Compared to other proteins in humans, FAM227B has high abundance of Phenylalanine and Glycine and low abundance levels of ...
The gene has been localized in humans to the 11th chromosome, with the specific location being 11p1.3. The protein encoded by ... "Detection of a homozygous four base pair deletion in the protein X gene in a case of pyruvate dehydrogenase complex deficiency ... Articles with short description, Short description matches Wikidata, Genes on human chromosome 11, Wikipedia articles ... The mRNA encoded by the human PDHX gene is approximately 2.5 kb in length, and expressed primarily in human skeletal and ...
Genes on human chromosome 8, Wikipedia articles incorporating text from the United States National Library of Medicine, Human ... The NDUFB9 gene is located on the q arm of chromosome 8 in position 13.3 and is 10,884 base pairs long. The NDUFB9 protein ... "The human B22 subunit of the NADH-ubiquinone oxidoreductase maps to the region of chromosome 8 involved in branchio-oto-renal ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ...
Articles with short description, Short description matches Wikidata, Genes on human chromosome 19). ... There are ten different exons and the ones expressed depend on how alternative splicing proceeds. There are four alternative ... some of which are membrane proteins The RNA product is 1483 base pairs long and is spliced alternatively to yield seven ... In humans, TM6SF2 expression has been documented in the adult stage only specifically in the intestine and liver in moderate ...
... contains a single circular chromosome of 1,587,646 base pairs. B. quintana is a fastidious, aerobic, Gram-negative(−), pole rod ... Its primary vector is known to be Pediculus humanus variety corporis, also known as the human body louse. It was first known to ... Although lice are animal vectors, humans (and some other primates) are the only known animal reservoir hosts for this bacterium ... Hadfield, T.L.; Warren, R.; Kass, M.; Brun, E.; Levy, C. (1993). "Endocarditis caused by Rochalimaea henselae". Human Pathology ...
10000000000; short scale: ten billion; long scale: ten thousand million, or ten milliard) Biology - bacteria in the human body ... Biology - base pairs in the genome: approximately 3.3×109 base pairs in the human genome. Linguistics: 3,400,000,000 - the ... Biology: Each human cell contains 46 chromosomes. Phonology: There are 47 phonemes in English phonology in Received ... Biology - Cells in the human body: The human body consists of roughly 1014 cells, of which only 1013 are human. The remaining ...
Genes on human chromosome X, Pages using multiple image with auto scaled images, Human proteins). ... Including 5' and 3' untranslated regions, isoform 1 is 18,515 base pairs long, spanning chromosome X at 40,626,921 - 40,647,554 ... Chromosome X Open Reading Frame 38 (CXorf38) is a protein which, in humans, is encoded by the CXorf38 gene. CXorf38 appears in ... UCSC entry on CXorf38 variant 1 "CXorf38 chromosome X open reading frame 38 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm ...
V. faba has a diploid (2n) chromosome number of 12 (six homologous pairs). Five pairs are acrocentric chromosomes and one pair ... In much of the English-speaking world, the name "broad bean" is used for the large-seeded cultivars grown for human food, while ... It is widely cultivated as a crop for human consumption, and also as a cover crop. Varieties with smaller, harder seeds that ... In Sardinia, broad beans are traditionally cooked with lard, often substituted or paired with bacon or minced pork. In Rome, ...
Also, transitions are less likely to result in amino acid substitutions (due to wobble base pair), and are therefore more ... Transition Aristolochic acid, a natural plant chemical causing A → T and T → A transversions in humans P53 Guanine DNA ... These mutations occur in different stages of the germ cell lineage and are distributed throughout the chromosomes. The location ... These products trigger mutations, leading to DNA damage, and can pair with adenine and guanine through hydrogen bonding causing ...