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*  Human artificial chromosome
Yeast artificial chromosomes and bacterial artificial chromosomes were created before human artificial chromosomes, which first ... A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That ... In 2010, a refined human artificial chromosome called 21HAC was reported. 21HAC is based on a stripped copy of human chromosome ... "A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary ...
*  Cloning vector
Insert of up to 3,000 kb may be carried by yeast artificial chromosome. Human artificial chromosome may be potentially useful ... "Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells". ... Kouprina N, Earnshaw WC, Masumoto H, Larionov V (2013). "A new generation of human artificial chromosomes for functional ... Insert size of up to 350 kb can be cloned in bacterial artificial chromosome (BAC). BACs are maintained in E. coli with a copy ...
*  Case Western Reserve University School of Medicine
1997 - Team led by Professor Huntington Willard (Chair of Genetics) create world's first artificial human chromosome. M. Scott ... of the world's first human artificial chromosome. Integrated MD-PhD Training: In 1956, CWRU School of Medicine began an ... 1975 - Discovery that human renin, an enzyme produced by the kidney, is involved in hypertension 1990 - National team led by ... Research History: Development of the modern technique for human blood transfusion using a cannula to connect blood vessels; ...
*  Bacterial artificial chromosome
Cosmid End-sequence profiling Fosmid Human artificial chromosome Yeast artificial chromosome O'Connor M, Peifer M, Bender W ( ... A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F-plasmid), used for ... The bacterial artificial chromosome's usual insert size is 150-350 kbp. A similar cloning vector called a PAC has also been ... BACs can also be utilized to detect genes or large sequences of interest and then used to map them onto the human chromosome ...
*  Germinal choice technology
Germline engineering and even the engineering of human artificial chromosomes (which presently allow increased reliability) are ... This had already been done in mice and, if successful in humans, could be the first case of germline engineering. Designer baby ... Chinese scientists reported in 2015 that they had modified the genomes of non-viable human embryos, Fredreik Lanner, a Swedish ... Callaway, Ewen (2016-02-04). "UK scientists gain licence to edit genes in human embryos". Nature. 530 (7588): 18-18. doi: ...
*  P1-derived artificial chromosome
Bacterial artificial chromosome Human artificial chromosome Yeast artificial chromosome Michael Yarmolinsky, Ronald Hoess (2015 ... Online Medical Dictionary P1-derived artificial chromosome P1-derived artificial chromosome (PAC) definition. ... The P1-derived artificial chromosome are DNA constructs that are derived from the DNA of P1 bacteriophage. They can carry large ...
*  Tac-Promoter
... genetics/expression-vectors.html Human artificial chromosome Yeast artificial chromosome Bacterial artificial chromosome. ...
*  Genomic library
June 1996). "Construction and characterization of a human bacterial artificial chromosome library". Genomics. 34 (2): 213-8. ... P1 artificial chromosomes (PACs) have features of both P1 vectors and Bacterial Artificial Chromosomes (BACs). Similar to P1 ... Yeast artificial chromosomes (YACs) are linear DNA molecules containing the necessary features of an authentic yeast chromosome ... Bacterial artificial chromosomes (BACs) are circular DNA molecules, usually about 7kb in length, that are capable of holding ...
*  Index of molecular biology articles
... human artificial chromosome - Human Genome Project - human immunodeficiency virus - Huntington's disease - hybridization - ... bacterial artificial chromosome - bacteriophage - bacteriophage lambda - band shift assay - base - base pair - binding site - ... yeast artificial chromosome) zinc finger - Index of biochemistry articles. ... chromosome - Chromosomal translocation - chromosome walking - CIS - cistron - clone (genetics) - clone (noun) - clone (verb) - ...
*  RNA
Heard E; Mongelard F; Arnaud D; Chureau C; Vourc'h C; Avner P (1999). "Human XIST yeast artificial chromosome transgenes show ... There are many long noncoding RNAs that regulate genes in eukaryotes, one such RNA is Xist, which coats one X chromosome in ... Yu Q; Morrow CD (2001). "Identification of critical elements in the tRNA acceptor stem and TΨC loop necessary for human ... R.N. Shukla (2014-06-30). Analysis of Chromosomes. ISBN 9789384568177. Berg JM; Tymoczko JL; Stryer L (2002). Biochemistry (5th ...
*  Trifunctional purine biosynthetic protein adenosine-3
"Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes". EMBO J. 10 (7): 1629-34. PMC 452831 ... 2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311-9. doi:10.1038/35012518. PMID 10830953. Banerjee D, ... 1997). "The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development ... Trifunctional purine biosynthetic protein adenosine-3 is an enzyme that in humans is encoded by the GART gene. This protein is ...
*  Huntington Willard
... and the first reported development of human artificial chromosomes for studies of gene transfer and functional genomics. ... His current research interests include genome sciences and their broad implications for medicine and society, human chromosome ... In 2014, he was named to head the Marine Biological Laboratory, and a professor in human genetics at the University of Chicago ...
*  HNRPA3
1993). "A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, ... 2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724-31. doi:10.1038/ ... Heterogeneous nuclear ribonucleoprotein A3 is a protein that in humans is encoded by the HNRNPA3 gene. GRCh38: Ensembl release ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
*  HAC
... a crude oil with a high concentration of naphthenic acids Human artificial chromosome Newey-West HAC estimator Hierarchical ...
*  Microcell-mediated chromosome transfer
... mice with large pieces from human chromosomes as well as new methods for human and mouse artificial chromosomes. Doherty AM, ... "A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of ... maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human ... Fournier RE, Ruddle FH (Jan 1977). "Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human ...
*  List of MeSH codes (G14)
... artificial, human MeSH G14.162.520.300 --- chromosomes, human MeSH G14.162.520.300.117 --- chromosomes, artificial, human MeSH ... chromosomes, artificial, human MeSH G14.162.178.195 --- chromosomes, artificial, p1 bacteriophage MeSH G14.162.178.200 --- ... chromosomes, artificial, human MeSH G14.337.249.195 --- chromosomes, artificial, p1 bacteriophage MeSH G14.337.249.200 --- ... human, pair 5 MeSH G14.162.520.300.325 --- chromosomes, human, 6-12 and x MeSH G14.162.520.300.325.330 --- chromosomes, human, ...
*  Rolling circle replication
"Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study of DNA replication intermediates". ... For instance, human herpesvirus-6 (HHV-6)(hibv) expresses a set of "early genes" that are believed to be involved in this ... Human Papillomavirus-16 (HPV-16) is another virus that employs rolling replication to produce progeny at a high rate. HPV-16 ... "The molecular biology of human herpesvirus-6 latency and telomere integration". Microbes and infection. 13 (8-9). doi:10.1016/j ...
*  Concatemer
"Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study of DNA replication intermediates". ... In the case of human herpesvirus-6, its entire genome is made over and over on a single strand. These long concatemers are ... "The molecular biology of human herpesvirus-6 latency and telomere integration". Microbes and infection. 13 (8-9). doi:10.1016/j ...
*  Yeast artificial chromosome
Bacterial artificial chromosome (BAC) Cosmid Fosmid Genetic engineering Human artificial chromosome Autonomously replicating ... "Mapping human chromosomes by walking with sequence-tagged sites from end fragments of yeast artificial chromosome inserts". ... Whole human chromosomes have been examined, such as the X chromosome, generating the location of genetic markers for numerous ... Yeast artificial chromosomes (YACs) are genetically engineered chromosomes derived from the DNA of the yeast, Saccharomyces ...
*  Amyotrophic lateral sclerosis research
In that study they chose the bacterial artificial chromosome that has the human length of C9orf72 gene, and they introduced ... Fruit fly ALS models can be used to study the locomotion and eye changes that can be related to human symptoms. Thus, drugs can ... which has shown promise in both in-vitro and in-vivo models of ALS but is yet to be effective in human models of ALS and ... and it is very beneficial in increasing the expression of the genes to mimic the human model of ALS for a faster onset of the ...
*  Artificial chromosome
... may refer to: Yeast artificial chromosome Bacterial artificial chromosome Human artificial chromosome P1- ... derived artificial chromosome Synthetic DNA of a base pair size comparable to a chromosome. ...
*  Outline of genetics
... cell heterozygous highly conserved sequence holoprosencephaly homologous recombination homozygous human artificial chromosome ( ... Genetics of intelligence Genetic testing Genomics Human genetics Human evolutionary genetics Human mitochondrial genetics ... HAC) Human Genome Project human immunodeficiency virus (HIV) acquired immunodeficiency syndrome (AIDS) hybridization ... gene syndrome technology transfer transgenic trisomy tumor suppressor gene vector Western blot yeast artificial chromosome (YAC ...
*  OR10G3
"Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4 ... OR10G3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ... Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9 ... Olfactory receptor 10G3 is a protein that in humans is encoded by the OR10G3 gene. Olfactory receptors interact with odorant ...
*  OR4E2
"Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4 ... 1994). "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA ... OR4E2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9 ...
*  MTAP
1995). "Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine ... "Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization". ... S-methyl-5'-thioadenosine phosphorylase is an enzyme that in humans is encoded by the MTAP gene. This gene encodes an enzyme ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
*  Promoter (genetics)
"Gene promoters show chromosome-specificity and reveal chromosome territories in humans". BMC Genomics. 14 (278): 278. doi: ... artificial promoters with complete conservation of the -10 and -35 elements have been found to transcribe at lower frequencies ... Furthermore, in humans, promoters show certain structural features characteristic for each chromosome. Core promoter - the ... In humans, DNA methylation occurs at the 5' position of the pyrimidine ring of the cytosine residues within CpG sites to form 5 ...