Muehlschlegel JD, Liu KY, Perry TE, Fox AA, Collard CD, Shernan SK, Body SC (September 2010). "Chromosome 9p21 variant predicts ... Because of this, the reported associated variants are unlikely to be the actual causal variants. Associated regions can contain ... is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated ... Because so many variants are tested, it is standard practice to require the p-value to be lower than 5×10−8 to consider a ...
June 2007). "A common variant on chromosome 9p21 affects the risk of myocardial infarction". Science. 316 (5830): 1491-1493. ... Cunnington MS, Santibanez Koref M, Mayosi BM, Burn J, Keavney B (April 2010). Gibson G (ed.). "Chromosome 9p21 SNPs Associated ... November 2009). Reitsma PH (ed.). "Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. ... December 2010). "Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma ...
2009). "INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis". PLOS ONE. 4 (4 ... This was first published study identifying the underlying mechanism of 9p21.3, a genetic risk variant with the strongest, and ...
"Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide ... October 2011). "A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD". Neuron. 72 (2): ... C9orf72 (chromosome 9 open reading frame 72) is a protein which in humans is encoded by the gene C9orf72. The human C9orf72 ... C9orf72 chromosome 9 open reading frame 72 [Homo sapiens] - Gene - NCBI DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, ...
"INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis". PLOS ONE. 4 (4): e5027. ... Xist RNA also localises the histone variant macroH2A to the inactive X-chromosome. There are additional ncRNAs that are also ... The expression of Xist from the future inactive X-chromosome, and its subsequent coating of the inactive X-chromosome, occurs ... A cis-acting locus that controls chromosome-wide replication timing and stability of human chromosome 15". PLOS Genetics. 11 (1 ...
"A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction," Science (subscription required), Vol. 316, ... They discovered the chromosome 8q24 locus as harboring risk variants for many types of cancer, and variants in the TERT, TP53 ... deCODE has discovered a number of sequence variants linked to risk of prostate cancer (as well as a protective variant), breast ... "Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes," op. cit. G ...
The CDKN2A (p16) and CDKN2B (p15) loci on chromosome 9p21 are frequently deleted in chordomas Another study found CDKN2A ... There are three histological variants of chordoma: conventional, chondroid and dedifferentiated. The histological appearance of ... Genes Chromosomes Cancer. 41 (1): 80-5. doi:10.1002/gcc.20052. PMID 15236319. S2CID 13136963. Han S, Polizzano C, Nielsen GP, ...
UroVysion is a fluorescence in situ hybridization which detects aneuploidy in chromosomes 3, 7, 17 and loss of the 9p21 locus. ... "Urothelial Carcinoma Variants - American Urological Association". www.auanet.org. Archived from the original on 30 July 2020. ... Deletions of parts or whole of chromosome 9 is common in bladder cancer. Low grade cancer are known to harbor mutations in RAS ... Klaile Y, Schlack K, Boegemann M, Steinestel J, Schrader AJ, Krabbe LM (October 2016). "Variant histology in bladder cancer: ...
2010). "Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study". Lancet Neurol. 9 (10): ... 2010). "Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone ... This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, Wikipedia articles ...
10 February 2011). "9p21 DNA Variants Associated with Coronary Artery Disease Impair Interferon-Gamma Signaling Response". ... Recent advancements in the screening of chromatin signatures on chromosomes (for instance, chromosome conformation capture, ... For example, in a study on chromosomes 2 and 4, which have been linked to several genetic diseases, there were elevated GpC ... Early genome wide association studies were focused on the 8q24 region (residing on chromosome 8) due to the abnormally high ...
The CDKN2A gene resides on chromosome 9 at the band 9p21 and contains 8 exons. This gene encodes two proteins, p16 and p14ARF, ... A variant in the CDKN2A locus present in the founder of Bernese mountain dogs around 200 years ago predisposes the breed to ... The CDKN2A gene is located on the chromosome 9p21 locus, which is intriguing for several reasons. First, this region is well ... Ye S, Willeit J, Kronenberg F, Xu Q, Kiechl S (July 2008). "Association of genetic variation on chromosome 9p21 with ...
2010). "Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, All stub articles, ... "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". ...
"A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD". Neuron. 72 (2): 257-268. doi: ... "Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis". JAMA Neurology. 78 (10): 1236-1248. ...
... (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. It is ... The 9p21 locus was significantly associated with coronary artery calcification (rs1537370). Subsequently, two loci at ADAMTS7 ( ... August 2010). "Additive effect of multiple genetic variants on the risk of coronary artery disease". Revista Espanola de ... The PHACTR1 gene resides on chromosome 6 at the band 6p24.1 and includes 19 exons. This gene produces 2 isoforms through ...
... chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21". ... Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain ... The MTAP gene location is 9p21.3 which is chromosome 9, p arm, band 2, sub-band1, and sub-sub-band 3. The MTAP gene has seven ... Due to the nature of the MTAP gene and the surrounding genes of chromosome 9, deletion of the genes around p21, and gene p21 ...
This contact between the asbestos fiber and the chromosomes or structural proteins of the spindle apparatus can induce complex ... Before the use of advanced microscopy techniques, malignant mesothelioma was often diagnosed as a variant form of lung cancer. ... Chiosea S, Krasinskas A, Cagle PT, Mitchell KA, Zander DS, Dacic S (June 2008). "Diagnostic importance of 9p21 homozygous ... Other frequent abnormalities include structural rearrangement of 1p, 3p, 9p and 6q chromosome arms.[citation needed] Common ...
Other genome-wide studies have identified a firm risk variant on chromosome 9 (9p21.3). However, these and other loci are found ... Roberts R, Stewart AF (January 2012). "9p21 and the genetic revolution for coronary artery disease". Clinical Chemistry. 58 (1 ... A region on chromosome 17 was confined to families with multiple cases of myocardial infarction. ... "Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17". PLOS ...