The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

Subsequently, factors such as Platelet-derived growth factor AA (PDGF-AA) and Insulin-like growth factor 1 (IGF-1) are added to ... The observation of paranodal and nodal assembly is protocol dependent, some observe paranodal and nodal assembly, some do not. ... In 2020, researchers described an approach to obtain meaningful scRNA seq and assay for transposase-accessible chromatin using ... To promote formation of neurons from neural precursor cells, brain-derived neurotrophic factor (BDNF) and neurotrophic factor 3 ...

El Kharroubi A, Piras G, Zensen R, Martin MA (1998). "Transcriptional activation of the integrated chromatin-associated human ... "Prothymosin alpha binds histones in vitro and shows activity in nucleosome assembly assay". Biochim. Biophys. Acta. 1296 (2): ... The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes ... Deng L, de la Fuente C, Fu P, Wang L, Donnelly R, Wade JD, Lambert P, Li H, Lee CG, Kashanchi F (2001). "Acetylation of HIV-1 ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

DNA replication licensing factor MCM2 is a protein that in humans is encoded by the MCM2 gene. The protein encoded by this gene ... DaFonseca CJ, Shu F, Zhang JJ (Mar 2001). "Identification of two residues in MCM5 critical for the assembly of MCM complexes ... Fujita M, Yamada C, Tsurumi T, Hanaoka F, Matsuzawa K, Inagaki M (1998). "Cell cycle- and chromatin binding state-dependent ... Kneissl M, Pütter V, Szalay AA, Grummt F (Mar 2003). "Interaction and assembly of murine pre-replicative complex proteins in ...

SWI/SNF is a chromatin remodeling complex. Artificial tethering of BRCA1 to chromatin was shown to decondense heterochromatin, ... Neish AS, Anderson SF, Schlegel BP, Wei W, Parvin JD (February 1998). "Factors associated with the mammalian RNA polymerase II ... "Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex". Proc. Natl. Acad. Sci. U.S.A. 100 ( ... Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R (2001). "BRCA1-induced large-scale chromatin unfolding and allele-specific ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

... these exon definition interactions are necessary to allow the binding of core splicing factors prior to assembly of the ... Recent provocative studies point to a key function of chromatin structure and histone modifications in alternative splicing ... If SC35 binds to the ESE, it prevents A1 binding and maintains the 5' donor site in an accessible state for assembly of the ... That is, a splicing factor that serves as a splicing activator when bound to an intronic enhancer element may serve as a ...

11] Wei, Q., Zhang, Y., Li, Y., Zhange, Q., Ling, K, and Hu, J. (Aug 2012). The BBSome controls IFT assembly and turnaround in ... Arl6 is an ARF(ADP Ribosylation Factor)-like GTPase that helps recruit the BBSome to the ciliary membranes. It is comparable to ... Looking at the involvement of BBS6 in overseeing the SWI/SNF chromatin remodeling complex has provided signs that this BBS ... It has been shown that this leads to dysfunction in the assembly of the BBSome which can have detrimental effects on systems ...

... plus histone and chromatin modifying factors. In certain circumstances, the MMR pathway may recruit an error-prone DNA ... Heller RC, Marians KJ (December 2006). "Replisome assembly and the direct restart of stalled replication forks". Nature Reviews ... The histone modification H3K36me3, an epigenetic mark of active chromatin, has the ability to recruit the MSH2-MSH6 (hMutSα) ... Li GM (July 2014). "New insights and challenges in mismatch repair: getting over the chromatin hurdle". DNA Repair. 19: 48-54. ...

CUT&Tag-sequencing can be used to examine gene regulation or to analyze transcription factor and other chromatin-associated ... "Effects of GC Bias in Next-Generation-Sequencing Data on De Novo Genome Assembly". PLOS ONE. 8 (4): e62856. Bibcode:2013PLoSO ... CUT&Tag sequencing is an improvement over CUT&RUN because it does not require cells to be lysed or chromatin to be fractionated ... Specific DNA sites in direct physical interaction with proteins such as transcription factors can be isolated by Protein-A (pA ...

Par14 is found in pre-ribosomal ribonuclear protein complexes, where it acts as an rRNA processing factor. Photoaffinity ... After dephosphorylation the protein associates to chromatin, with the N-terminus mainly responsible for high-affinity DNA ... "Parvulin 17 Promotes Microtubule Assembly by Its Peptidyl-Prolyl Cis/Trans Isomerase Activity". Journal of Molecular Biology. ... DNA repair and/or chromatin remodeling. Par14 requires phosphorylation of Ser7 and Ser9 by protein kinase B (Akt) (or protein ...

This modification promotes the assembly of transcription factors via the loosening of chromatin and the ability of acetyl ... The HPA axis is important for regulating the wake-sleep cycle but works with other factors that help modulate sleep as well. ... There are several genetic factors such as HLA-DQB*6:02 that have been identified as possibly playing a role in the development ... There has been growing evidence of the role heritability has on insomnia development but the main factor that determines if a ...

... as well as chromatin-dependent gene silencing (CDGS) pathways. CDGS involves the assembly of small RNA complexes on nascent ... that function as factors involved in inactivating homologous sequences, promoting endonuclease activity, translational arrest, ... piRNAs appear to act both at the post-transcriptional and chromatin levels. They are distinct from miRNA due to at least an ... This is significant at least because the evidence suggests that small RNAs play a role in the modulation of chromatin structure ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

In another model, chromatin loop extrusion is pushed by transcription generated supercoiling ensuring also that cohesin ... which are part of a complex mechanism termed the spindle assembly checkpoint. It is not clear how the cohesin ring links sister ... rings are found in chromosome arms that have AT-rich DNA sequences indicating that DNA sequence may be an independent factor of ... The loop extrusion process stops when cohesin encounters the architectural chromatin protein CTCF. The CTCF site needs to be in ...

"The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly". Cell. 118 ... An example of this is the binding of tumour necrosis factor-alpha (TNF-alpha) to TNF-alpha receptor. An example of a TNF ... During prophase, as the chromatin condenses so that it is visible under the microscope, survivin starts to move to the ... Instead, it is observed that modification of the chromatin inside of the promoter region may be responsible for the ...

... plays a role of an accessory factor. Its primary function seems to be to interact with RAG1 protein and activate its ... A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, ... Oettinger MA, Schatz DG, Gorka C, Baltimore D (June 1990). "RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J ... RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex†. American Society for Microbiology. ...

The efficiency of this process was later enhanced by the addition of stem cell factor (SCF), epidermal growth factor (EGF), ... April 2008). "Chromatin dynamics during epigenetic reprogramming in the mouse germ line". Nature. 452 (7189): 877-81. Bibcode: ... Svingen T, Koopman P (November 2013). "Building the mammalian testis: origins, differentiation, and assembly of the component ... Transcription factor T acts upstream of BLIMP1 and Prdm14 in PGC specification by binding to the genes respective enhancer ...

This type of regulation can occur in different ways: the RNA transcript can directly bind to the transcription factor as a co- ... In addition to directly affecting chromatin structure, there are a number of ways in which SINEs can potentially regulate gene ... two types of RNA vital to ribosomal assembly and mRNA translation. SINEs, like tRNAs and many small-nuclear RNAs possess an ... These non-coding RNAs, which lie adjacent to or overlap gene-sets provide a mechanism by which transcription factors and ...

UAP56 is recognized as an RNA helicase but acts as a splicing factor required for early spliceosome assembly. Another factor ... by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin- ... It is organized around the eIF4AIII factor. The factor itself consists of two different types of conformations around the mRNA ... The core of the EJC contains the protein eukaryotic initiation factor 4A-III (eIF4A-III; a DEAD-box RNA helicase) bound to an ...

... is an adaptor protein that plays a key role in the proper assembly of the FA core complex. The FA core complex is ... FoxF1 protein also interacts with the FA protein core and induces its binding to chromatin to promote DNA repair. DNA damage ... Pradhan A, Ustiyan V, Zhang Y, Kalin TV, Kalinichenko VV (January 2016). "Forkhead transcription factor FoxF1 interacts with ... the link between Fanconi anaemia complex assembly and activity". The EMBO Journal. 21 (13): 3414-23. doi:10.1093/emboj/cdf355. ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

The complexes formed by the looping of the DNA are known as chromatin. The basic structural unit of chromatin is the nucleosome ... Maruta H, Greer K, Rosenbaum JL (1986). "The acetylation of alpha-tubulin and its relationship to the assembly and disassembly ... The regulation of transcription factors, effector proteins, molecular chaperones, and cytoskeletal proteins by acetylation and ... Chromatin states were investigated in Drosophila cells by looking at the binding location of proteins in the genome. Use of ...

Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, Jentsch S (March 1999). "A novel ubiquitination factor, E4, is involved in ... Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D (April 2015). "Assembly and ... Histone ubiquitination alters chromatin structure and allows the access of enzymes involved in transcription. Ubiquitin on ... A heat-stable polypeptide present in these extracts, ATP-dependent proteolysis factor 1 (APF-1), was found to become covalently ...

Many genetic factors were found to be involved in the suppression of these class I KNOX genes in leaf primordia (such as ... "Genome Assembly". The Arabidopsis Information Resource. Archived from the original on 7 March 2021. Retrieved 29 March 2016. " ... and the accessibility of the chromatin. Understanding how plants achieve resistance is important to protect the world's food ... Johnson C, Boden E, Arias J (August 2003). "Salicylic acid and NPR1 induce the recruitment of trans-activating TGA factors to a ...

Méndez, J; Stillman B (November 2000). "Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome ... "Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells". J. Mol. Biol. England. 327 (1): ... "Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F". Oncogene. 17 ... Méndez J, Stillman B (2000). "Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance ...

Silencing lachrymatory factor synthase in onions have produced tearless onions and RNAi has been used in BP1 genes in rapeseeds ... Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD (October 2003). "Asymmetry in the assembly of the RNAi enzyme complex ... Holmquist GP, Ashley T (2006). "Chromosome organization and chromatin modification: influence on genome function and evolution ... Instead, the R2D2 protein may serve as the differentiating factor by binding the more-stable 5′ end of the passenger strand. ...