Chondrogenesis
... during chondrogenesis. Noggin, a developmental protein, inhibits chondrogenesis by preventing condensation and differentiation ... Chondrogenesis at the U.S. National Library of Medicine Medical Subject Headings (MeSH) DeLise, A.M.; Fischer, L.; Tuan, R.S. ( ... Chondrogenesis is the process by which cartilage is developed. In embryogenesis, the skeletal system is derived from the ... L-Sox5 is also thought to be involved primarily in embryonic chondrogenesis, while Sox6 is thought to be involved in post-natal ...
Stimulator of chondrogenesis 1
... is a protein that in humans is encoded by the SCRG1 gene. Scrapie-responsive gene 1 is ... "Entrez Gene: Stimulator of chondrogenesis 1". Retrieved 2018-10-01. Aomatsu E, Takahashi N, Sawada S, Okubo N, Hasegawa T, ...
Autologous matrix-induced chondrogenesis
... (AMIC) is a treatment for articular cartilage damage. It combines microfracture ... Shaikh, N; Seah, MKT; Khan, WS (18 July 2017). "Systematic review on the use of autologous matrix-induced chondrogenesis for ... Autologous Matrix Induced Chondrogenesis (AMIC) surgery is a single step procedure. After arthroscopic evaluation of the ...
NKX3-2
2014). "The role of Nkx3.2 in chondrogenesis". Frontiers in Biology. 9 (5): 376-381. doi:10.1007/s11515-014-1321-3. PMC 4859764 ...
Gordana Vunjak-Novakovic
L. E. Freed; A. P. Hollander; I. Martin; J. R. Barry; R. Langer; G. Vunjak-Novakovic (1998). "Chondrogenesis in a cell-polymer- ...
HIF1A
Schipani E (2006). "Hypoxia and HIF-1 alpha in chondrogenesis". Seminars in Cell & Developmental Biology. 16 (4-5): 539-46. doi ...
Disease-modifying osteoarthritis drug
"LNA043: Chondrogenesis inducer for cartilage repair" (PDF). Meet Novartis Management NIBR. Clinical trial number NCT02491281 ... May 2005). "Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis". The Journal of ... of the small compound TD-198946 on glycosaminoglycan synthesis and transforming growth factor β3-associated chondrogenesis of ...
Von Hippel-Lindau tumor suppressor
Schipani E (2006). "Hypoxia and HIF-1 alpha in chondrogenesis". Seminars in Cell & Developmental Biology. 16 (4-5): 539-46. doi ...
Cartilage oligomeric matrix protein
Liu C (2006). "Transcriptional mechanism of COMP gene expression and chondrogenesis". Journal of Musculoskeletal & Neuronal ...
SOX5
The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple ... Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene". The EMBO Journal. 17 (19 ...
Vasoactive intestinal peptide
Juhász T, Helgadottir SL, Tamás A, Reglődi D, Zákány R (April 2015). "PACAP and VIP signaling in chondrogenesis and ...
SULF1
Additional studies emphasized the role of Sulfs in chondrogenesis. The role of QSulf1 was determined in quail cartilage ... 2008). Also, the zone of proliferating chondrocytes was reduced by 90%, indicating defects in chondrogenesis. The important ... Because Sulfs were important in normal chondrogenesis, they were investigated in cartilage diseases. Expression patterns of ... indicating QSulf1 is needed for early chondrogenesis. QSulf1 displayed perichondrial staining during early development but was ...
Osteochondroprogenitor cell
TGF-β will act as a stimulator of chondrogenesis, and an inhibitor of osteoblastic differentiation, by blocking the Runx2 ... "The role of TGFβs and Sox9 during limb chondrogenesis". Current Opinion in Cell Biology. 18 (6): 723-729. doi:10.1016/j.ceb. ... as the sites for osteogenesis and chondrogenesis are now known. Osteochondroprogenitor can be found between MSCs and the ... suggesting that they are important in chondrogenesis. Osteoblasts are cells that group together to form units, called osteons, ...
Mir-455 microRNA precursor family
"The expression and function of microRNAs in chondrogenesis and osteoarthritis". Arthritis and Rheumatism. 64 (6): 1909-19. doi: ...
Mir-337 microRNA precursor family
"MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expression". Osteoarthritis and Cartilage. 20 (6): 593 ...
Bat wing development
"Regulation of growth plate chondrogenesis by bone morphogenetic protein-2". Endocrinology. 142 (1): 430-436. doi:10.1210/endo. ...
C4orf36
A study on chondrogenesis found that c4orf36 has an oscillatory expression pattern coupled to that of ATP, indicating a ... "Analysis of proteins showing differential changes during ATP oscillations in chondrogenesis". Cell Biochemistry and Function. ...
CYP26B1
"Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis". J. Cell Sci. 124 (16): 2723- ...
Osteochondritis dissecans
1995). "Effects of human knee synovial fluid on chondrogenesis in vitro". The American Journal of Knee Surgery. 8 (4): 124-9. ... supporting both osteogenesis and chondrogenesis. With disruption of the epiphyseal plate vessels, varying degrees and depth of ...
Darcy Kelley
Androgen-induced myogenesis and chondrogenesis in the larynx of Xenopus laevis . Dev. Biol. 113, 135 -145. Tobias, M. and ... Sassoon, David; Segil, Neil; Kelley, Darcy (1986). "Androgen-induced myogenesis and chondrogenesis in the larynx of Xenopus ... that these hormones control myogenesis and chondrogenesis in the vocal organ, the larynx, and that the greater sensitivity of ...
CTGF
"Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development". Development. 130 (12 ...
Perlecan
Gomes RR, Farach-Carson MC, Carson DD (2004). "Perlecan functions in chondrogenesis: insights from in vitro and in vivo models ...
In vivo bioreactor
"Supramolecular GAG-like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration". doi:10.1021/ ... site is used because stimulation of the cambium layer using transforming growth factor-beta resulted in enhanced chondrogenesis ...
Peter Koopman
"The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos". Nature Genetics. 9 (1): 15-20. doi:10.1038/ ...
FGF18
Subsequent studies identified FGF18's role in promoting chondrogenesis, and an apparent specific activity for the generation of ... chondrogenesis). FGF18 and has been shown to cause thickening of cartilage in a murine model of osteoarthritis, and the ... "Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis". ... "Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis". ...
BMPR1A
"Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo". Proc. Natl. Acad. Sci. U.S.A. 102 ( ...
Fibroblast growth factor receptor
May 2005). "Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis". The Journal of ...
Hyaline cartilage
"Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis". ... 18 signals through FGF receptor 3 to promote chondrogenesis". The Journal of Biological Chemistry. 280 (21): 20509-20515. doi: ...
BMPR1B
"Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo". Proc. Natl. Acad. Sci. U.S.A. 102 ( ...
GDF11
Gamer LW, Cox KA, Small C, Rosen V (January 2001). "Gdf11 is a negative regulator of chondrogenesis and myogenesis in the ...