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*  Sterol O-acyltransferase
... cholesterol acyltransferase. It gives the cholesterol ester cholesterol oleate. from Sigrid Hahn; Hans-Ulrich Klör (2001). ... The rate-controlling enzyme in cholesterol catabolism, hepatic cholesterol 7-hydroxylase, is believed to be regulated partly by ... Spector AA, Mathur SN, Kaduce TL (1979). "Role of acylcoenzyme A: cholesterol o-acyltransferase in cholesterol metabolism". ... cholesterol ester Thus, the two substrates of this enzyme are acyl-CoA and cholesterol, whereas its two products are CoA and ...
*  Perilipin-2
"Predominance of a proinflammatory phenotype in monocyte-derived macrophages from subjects with low plasma HDL-cholesterol". ... "Enhanced atheroprotection and lesion remodelling by targeting the foam cell and increasing plasma cholesterol acceptors". ...
*  Farnesoid X receptor
Kalaany NY, Mangelsdorf DJ (2006). "LXRS and FXR: the yin and yang of cholesterol and fat metabolism". Annual Review of ... One of the primary functions of FXR activation is the suppression of cholesterol 7 alpha-hydroxylase (CYP7A1), the rate- ... Bramlett KS, Yao S, Burris TP (Dec 2000). "Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha- ... "The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors". ...
*  Lipid metabolism
... see also lipolysis and lipogenesis Cholesterols Steroid - see also steroidogenesis Fatty acids - see also fatty acid metabolism ...
*  Bile
The cholesterol contained in bile will occasionally accrete into lumps in the gallbladder, forming gallstones. Cholesterol ... The composition of gallbladder bile is 97% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats (cholesterol, fatty acids and ...
*  Obeticholic acid
However concerns about longterm safety issues such as increased cholesterol and adverse cardiovascular events may warrant the ...
*  Lipid profile
Total lipids Serum total cholesterol serum HDL cholesterol Total cholesterol/HDL cholesterol ratio Serum triglycerides serum ... someone's total cholesterol may be high, but this may be due to very high HDL ("good cholesterol") cholesterol levels,-which ... National Cholesterol Education Program (Ncep) Expert Panel On Detection, E. (2002). "Third Report of the National Cholesterol ... while a high total cholesterol level may help give an indication that there is a problem with cholesterol levels, the ...
*  Cholesterol oxidase
In enzymology, a cholesterol oxidase (EC 1.1.3.6) is an enzyme that catalyzes the chemical reaction cholesterol + O2 ⇌ {\ ... The systematic name of this enzyme class is cholesterol:oxygen oxidoreductase. Other names in common use include cholesterol- ... Coulombe R, Yue KQ, Ghisla S, Vrielink A (August 2001). "Oxygen access to the active site of cholesterol oxidase through a ... The substrate-binding domain found in some bacterial cholesterol oxidases is composed of an eight-stranded mixed beta-pleated ...
*  Cholesterol embolism
... (often cholesterol crystal embolism or atheroembolism, sometimes blue toe or purple toe syndrome or trash ... They probably lead to cholesterol emboli by removing blood clots that cover up a damaged atherosclerotic plaque; cholesterol- ... In kidney failure resulting from cholesterol crystal emboli, statins (medication that reduces cholesterol levels) have been ... The diagnostic histopathologic finding is intravascular cholesterol crystals, which are seen as cholesterol clefts in routinely ...
*  Anti-cholesterol
... is a naturally occurring antibody to cholesterol produced by mammals. This antibody serves a 'housekeeping' or ... January 1996). "Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced ... The antibody does not bind the good forms of cholesterol such as HDL. In the gastrointestinal tract, the antibody acts as a ... An immunoglobulin protein, anti-cholesterol may be found both in circulation as well as in the digestive tract. In circulation ...
*  Remnant cholesterol
... remnant cholesterol is all plasma cholesterol that is not LDL cholesterol or HDL cholesterol. According to one study, high ... Remnant cholesterol has about twice the association with ischemic heart disease as LDL cholesterol. Remnant cholesterol is ... Remnant cholesterol is especially predictive of coronary artery disease in patients with normal total cholesterol. High plasma ... "Association of remnant-like particle cholesterol with coronary artery disease in patients with normal total cholesterol levels ...
*  Cholesterol sulfate
... , or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol. It is ... also known as cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of ... a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol. ... cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, ...
*  Reverse cholesterol transport
... is a multi-step process resulting in the net movement of cholesterol from peripheral tissues back ... The cholesterol is converted to cholesteryl esters by the enzyme LCAT (lecithin-cholesterol acyltransferase). The cholesteryl ... and these lipoproteins can be taken up by secreting unesterified cholesterol into the bile or by converting cholesterol to bile ... Cholesterol from non-hepatic peripheral tissues is transferred to HDL by the ABCA1 (ATP-binding cassette transporter). ...
*  Cholesterol 7alpha-monooxygenase
In enzymology, a cholesterol 7alpha-monooxygenase (EC 1.14.13.17) is an enzyme that catalyzes the chemical reaction cholesterol ... Mitton JR, Scholan NA, Boyd GS (1971). "The oxidation of cholesterol in rat liver sub-cellular particles The cholesterol-7- ... Boyd GS, Grimwade AM, Lawson ME (1973). "Studies on rat-liver microsomal cholesterol 7alpha-hydroxylase". Eur. J. Biochem. 37 ( ... The systematic name of this enzyme class is cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating). Other names in ...
*  Cholesterol 25-hydroxylase
In enzymology, a cholesterol 25-hydroxylase (EC 1.14.99.38) is an enzyme that catalyzes the chemical reaction cholesterol + AH2 ... Lund EG, Kerr TA, Sakai J, Li WP, Russell DW (1998). "cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic ... The systematic name of this enzyme class is cholesterol, hydrogen-donor:oxygen oxidoreductase (25-hydroxylating). This enzyme ... 24 Jan 2013). "Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25- ...
*  Cholesterol-dependent cytolysin
The presence of cholesterol in the target membrane is required for pore formation, though the presence of cholesterol is not ... Even though cholesterol is not required for intermedilysin (ILY) to bind to a target cell, the presence of cholesterol is ... The Thiol-activated Cholesterol-dependent Cytolysin (CDC) family (TC# 1.C.12) is a member of the MACPF superfamily. Cholesterol ... If cholesterol concentration exceeds a certain point, free cholesterol will begin to precipitate out of the membrane. The ...
*  Cholesterol 24-hydroxylase
Cholesterol-24 hydroxylase contributes to brain cholesterol homeostasis by hydroxylating cholesterol at carbon-24 to 24S- ... A single cholesterol molecule takes up the entirety of the active site, with the aliphatic tail of the cholesterol held in ... In enzymology, a cholesterol 24-hydroxylase (EC 1.14.13.98) is an enzyme that catalyzes the chemical reaction cholesterol + ... UniProt entry on Cholesterol-24 hydroxylase HMDB Database entry RCSB Protein Data Bank Entry Review on Cholesterol-24 ...
*  Cholesterol total synthesis
Other cholesterol schemes have also been developed: racemic cholesterol was synthesized in 1966 by W.S. Johnson, the enantiomer ... Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered ... The route from cholestanol to cholesterol was already known (see: Robinson synthesis). Woodward Cholesterol Synthesis @ ... The unnatural cholesterol molecule that has also been synthesized is called ent-cholesterol. The Robinson synthesis is an ...
*  Cholesterol absorption inhibitor
... cholesterol absorption inhibitors block the uptake of micellar cholesterol, thereby reducing the incorporation of cholesterol ... Cholesterol absorption inhibitors are a class of compounds that prevents the uptake of cholesterol from the small intestine ... Phytosterols are also cholesterol absorption inhibitors. There are two sources of cholesterol in the upper intestine: dietary ( ... By reducing the cholesterol content in chylomicrons and chylomicron remnants, cholesterol absorption inhibitors effectively ...
*  Lecithin-cholesterol acyltransferase
... (Thr123----Ile) and lecithin-cholesterol acyltransferase (Thr347----Met)". J. Clin. Invest ... 1992). "Interaction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol ... is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then ... Lecithin cholesterol acyltransferase deficiency Acyl-CoA:cholesterol acyltransferase (ACAT) GRCh38: Ensembl release 89: ...
*  Lecithin cholesterol acyltransferase deficiency
Cholesterol effluxes from cells as free cholesterol and is transported in HDL as esterified cholesterol. LCAT is the enzyme ... Lecithin cholesterol acyltransferase catalyzes the formation of cholesterol esters in lipoproteins. Symptoms of the familial ... cholesterol in HDL particles. However, there is only a partial deficiency because the enzyme remains active on the cholesterol ... high plasma unesterified cholesterol in HDL particles, and low cholesterol ester in HDL particles but normal levels in low- ...
*  National Cholesterol Education Program
The National Cholesterol Education Program is a program managed by the National Heart, Lung and Blood Institute, a division of ... NCEP main page Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults ( ... Its goal is to reduce increased cardiovascular disease rates due to hypercholesterolemia (elevated cholesterol levels) in the ...
*  Cholesterol 7 alpha-hydroxylase
The enzyme cholesterol 7 alpha hydroxylase catalyzes the reaction that converts cholesterol into cholesterol 7 alpha ... Cholesterol 7 alpha-hydroxylase is the rate-limiting enzyme in the synthesis of bile acid from cholesterol via the classic ... Cholesterol 7 alpha-hydroxylase also known as cholesterol 7-alpha-monooxygenase or cytochrome P450 7A1 (CYP7A1) is an enzyme ... Cholesterol 7 alpha-hydroxylase is a cytochrome P450 heme enzyme that oxidizes cholesterol in the position 7 using molecular ...
*  Cholesterol side-chain cleavage enzyme
... however its activity is limited by the supply of cholesterol in the inner membrane. The supplying of cholesterol to this ... Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage. ... Cholesterol Pregnenolone Cytochrome P450scc at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular ... Cholesterol and adrenodoxin interactions at equilibrium and during turnover". The Journal of Biological Chemistry. 256 (9): ...
*  The 8-Week Cholesterol Cure
He also recommends exercise and emphasizes the use of niacin as a cure for cholesterol. The New 8-Week Cholesterol Cure: The ... It includes information about cholesterol and what foods people can eat to immediately reduce cholesterol, as well as what ... More Than 200 Delicious Recipes Featuring the Foods Proven to Lower Cholesterol The 8-Week Cholesterol Cure: How to Lower Your ... The New 8-Week Cholesterol Cure is a 1987 health book by Robert Kowalski, who wrote it as a personal recollection about dealing ...