Chemicals and drugs. Medical search. Wikipedia

3 Drug interactions. *4 Chemical properties. *5 Biosynthesis. *6 Absorption and metabolism *6.1 Absorption ... Nanoparticles have been explored as a delivery system for various drugs, such as improving the oral bioavailability of drugs ... where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail. ... Chemical properties[edit]. The oxidized structure of CoQ10 is shown on the top-right. The various kinds of Coenzyme Q may be ...

Chemicals and drugs[edit]. Some chemicals and drugs selectively destroy pancreatic cells. Pyrinuron (Vacor), a rodenticide ... Immunosuppressive drugs[edit]. Cyclosporine A, an immunosuppressive agent, has apparently halted destruction of beta cells (on ... One reason for this is that introducing a new kidney requires taking immunosuppressive drugs such as cyclosporine, which allows ... "Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review". Environmental Health ...

A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A ... Research chemicals[edit]. *Amiflamine (FLA-336). *Viqualine (PK-5078). *2-Methyl-3,4-methylenedioxyamphetamine (2-Methyl-MDA) ... The designer drug 4-methylaminorex, which is an SNDRA and 5-HT2B agonist, has been reported to cause this effect as well. ... Amphetamines like MDMA, MDEA, MDA, and MBDB, among other relatives (see MDxx), are recreational drugs termed entactogens. They ...

JEL: L65 - Chemicals; Rubber; Drugs; Biotechnology. JEL: L66 - Food; Beverages; Cosmetics; Tobacco. JEL: L67 - Other Consumer ...

"Expert Opinion on Emerging Drugs. 12 (3): 479-92. doi:10.1517/14728214.12.3.479. PMID 17874974.. ... Chemical Reviews. 108 (1): 238-63. doi:10.1021/cr0682195. PMID 18181659.. ... Cardiovascular Drugs and Therapy. 21 (3): 171-94. doi:10.1007/s10557-007-6014-6. PMID 17373584.. ... which is now resulting in a new generation of more selective drugs with many potential medical uses. Some of these compounds ...

"Nitrogen Mustard - Chemotherapy Drugs - Chemocare". chemocare.com. Retrieved 2017-10-09.. *^ Jamieson, E. R.; Lippard, S. J. ( ... "Accounts of Chemical Research. 41 (7): 793-804. doi:10.1021/ar700246x. ISSN 0001-4842. PMC 2785109. PMID 18500830.. ... As a result, the function of these drugs is to serve as enzyme poisons rather than inhibitors. This can be applied to treat ... Because the toxicity of these drugs depends on TOP1 trapping, cellular sensitivity to these compounds depends directly on TOP1 ...

Chemical Peeling. American Society for Dermatological Surgery.. *Lasik Laser Eye Surgery. USA Food an Drugs Administration info ... can be carried out by chemicals (chemoablation), by lasers (laser ablation), by freezing (cryoablation), or by electricity ( ...

"DEA Drugs & Chemicals of Concern "Carisoprodol"". Archived from the original on 17 April 2011. Retrieved 29 April 2011.. ... Drug information for Patients, Drug information for Professionals. *. "SOMA 250 mg (carisoprodol) for Painful Musculoskeletal ... As with other GABAergic drugs, combination with other GABAergic drugs, including alcohol, as well as with sedatives in general ... mixed with other drugs, a combination of the above, etc.), genetic predisposition to drug abuse, and a history of substance ...

Baselt, R. (2011). Disposition of Toxic Drugs and Chemicals in Man (9th ed.). Seal Beach, CA: Biomedical Publications. pp. 1644 ... A Primer on the UN Drug Control Conventions. Transnational Institute "Drug Schedules; Schedule 1". US Drug Enforcement Agency, ... Firn, Richard (2010). Nature's Chemicals. Oxford: Biology. Pate, David W. (1994). "Chemical ecology of Cannabis". Journal of ... such as in the United States where the National Institute on Drug Abuse and Drug Enforcement Agency regulated sources of ...

ISBN 0-87341-832-8. "Federal Food, Drug, and Cosmetic Act". US Food and Drug Administration. "Food Chemicals Codex". United ... "Food Chemicals Codex". "FD&C Act Chapter IV: Food". US Food and Drug Administration. Ayres, Chris (27 February 2010), Clean ... In Mexico, a man who worked for drug cartels admitted to having disposed of more than 300 bodies with it. A 3-10% solution of ... In the United States, food-grade lye must meet the requirements outlined in the Food Chemicals Codex (FCC),[page needed] as ...

Armaments L65 Chemicals • Rubber • Drugs • Biotechnology • Plastics L66 Food • Beverages • Cosmetics • Tobacco • Wine and ...

"Food and Chemical Toxicology. 49: 1773-1781.. *^ "How Sulfa Drugs Work". National Institutes of Health (NIH). 2015-05-15. ... Sulfa drugs also act as competitive inhibitors. For example, sulfanilamide competitively binds to the enzyme in the ... These fatty acids inhibitors have been used as drugs to relieve pain because they can act as the substrate, and bind to the ... Dick RM (2011). "Chapter 2. Pharmacodynamics: The Study of Drug Action". In Ouellette R, Joyce JA. Pharmacology for Nurse ...

Chemical Biology & Drug Design. 76 (2): 100-6. doi:10.1111/j.1747-0285.2010.00991.x. PMID 20545947.. ... "Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode". ...

Drug and Chemical Toxicology. 19 (1-2): 85-96. doi:10.3109/01480549609002198. PMID 8804555.. ... The basic chemical structure of the lolines comprises a saturated pyrrolizidine ring, a primary amine at the C-1 carbon, and an ... The lolines may be neurotoxic to the insects, and differences in the chemical groups at the C-1-amine result in different ... Dahlman DL, Eichenseer H, Siegel MR (1991). "Chemical perspectives of endophyte-grass interactions and their implications to ...

Chemical and physical data. Formula. C23H29ClN6O3. ... Infobox drug articles with non-default infobox title. *Articles ... LBP-1 is a drug originally developed by Organon for the treatment of neuropathic pain,[1][2] and subsequently further developed ... Retrieved from "https://en.wikipedia.org/w/index.php?title=LBP-1_(drug)&oldid=810230865" ...

Qadir MI, Parveen A, Ali M (October 2015). "Cdc42: Role in Cancer Management". Chemical Biology & Drug Design. 86 (4): 432-9. ... "Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a ...

London: The Chemical Society.. *. Veselovskaya, N. B.; Kovalenko, A.E (2000). Drugs. Moscow: Triada-X.. ... a b c d e f g h i j k l m n o p q r s t Chemical Encyclopedia: isoquinoline alkaloids. xumuk.ru ... "The evolution of drug discovery: From traditional medicines to modern drugs. John Wiley & Sons. pp. 157-159. ISBN 9783527326693 ... a b c d Chemical Encyclopedia: alkaloids. xumuk.ru *^ Roberts, M. F. (Margaret F.) (1998). Alkaloids : Biochemistry, Ecology, ...

"Drug & Chemical Residues Methods". U.S. Food and Drug Administration.. .mw-parser-output cite.citation{font-style:inherit}.mw- ... Toxic chemical residues, wastes or contamination from other processes, are a concern in food safety. For example, the U.S. Food ... and Drug Administration (FDA) and the Canadian Food Inspection Agency (CFIA) have guidelines for detecting chemical residues ... It may also denote the undesired by-products of a chemical reaction. ...

Major chemical drug groups. Gastrointestinal tract/. metabolism (A). *stomach acid *Antacids. *H2 antagonists ... LA drugs are also often combined with other agents such as opioids for synergistic analgesic action.[1] Low doses of LA drugs ... Aronson, Jeffrey K. (2008-10-07). Meyler's Side Effects of Drugs Used in Anesthesia. Elsevier. ISBN 9780444532701. .. ... Drugs in anaesthesia". Current Opinion in Anesthesiology. 16 (4): 429-36. August 2003. doi:10.1097/00001503-200308000-00010. ...

Major chemical drug groups. Gastrointestinal tract/. metabolism (A). *stomach acid *Antacids. *H2 antagonists ... It belongs to the chemical class methyl xanthines (along with caffeine). It is prescribed in severe cases of asthma or those ... Additionally some psychostimulant drugs that have an amphetamine like mode of action, such as amphetamine,[7] methamphetamine, ... The three types of prescription bronchodilating drugs are β2("beta two")-adrenergic agonists (short- and long-acting), ...

by salts (but many drugs are the salts of organic acids, even when drug therapy is not called by names reflecting that) *by ... by specific chemical elements: *by metals: *by heavy metals: *by gold: chrysotherapy (aurotherapy) ... by drugs: pharmacotherapy, chemotherapy (also, medical therapy often means specifically pharmacotherapy). *by medical devices: ... by plant parts or extracts (but many drugs are derived from plants, even when the term phytotherapy is not used) *scientific ...

Chemical Biology & Drug Design. 67 (2): 101-114. doi:10.1111/j.1747-0285.2006.00347.x. PMID 16492158.. ... chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxys, and dyes. ... Precursor to chelation agents, drugs, and agrochemicals[edit]. A most prominent derivative of ethylenediamine is the chelating ... It is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.[6] ...

Infobox drug articles with non-default infobox title. *Chemical articles without CAS registry number ... This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.. *v ... 1-Amino-5-phosphonoindan-1-carboxylic acid (APICA) is a drug that is used in neuroscience research. It is a selective ... Retrieved from "https://en.wikipedia.org/w/index.php?title=APICA_(drug)&oldid=865052976" ...

Adam Huczynski (2012). "Salinomycin - a New Cancer Drug Candidate". Chemical Biology & Drug Design. 79 (3): 235-238. doi: ... C. Naujokat, R. Steinhart "Salinomycin as a Drug for Targeting Human Cancer Stem Cells", Journal of Biomedicine and ... "Drug shows cancer stem cells not invulnerable". New Scientist. 2009-08-13.. ... The study screened 16,000 different chemical compounds and found that only a small subset, including salinomycin and etoposide ...

Major chemical drug groups. Gastrointestinal tract/. metabolism (A). *stomach acid *Antacids. *H2 antagonists ... Treatment with an antihelminthic drug kills worms whose phenotype renders them susceptible to the drug, but resistant parasites ... WHO (2006). Preventive chemotherapy in human helminthiasis: coordinated use of anthelminthic drugs in control interventions: a ... These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of ...

Chemicals that do not have a ChemSpider ID assigned. *Infobox drug articles without a structure image ... U.S. Food and Drug Administration (FDA). Retrieved 20 March 2018.. *^ Berman, Keith. "SCIG: New Therapeutic Uses Beyond PI?" ( ... "U.S. Food and Drug Administration (FDA). 15 March 2018. Retrieved 3 May 2020.. ... "Experimental Alzheimer's drug Gammagard may stall memory decline, small study suggests". CBS News. 17 July 2012. Archived from ...

Drugs: Certain drugs may cause changes to hearing, including deafness.. *Chemicals: Certain chemicals can damage the ear. ...

They are commonly used as acidity regulators and have the collective E number E339.[12] The United States Food and Drug ... Trisodium phosphate (TSP) is the inorganic compound with the chemical formula Na3PO4. It is a white, granular or crystalline ...

... as well as certain drugs and other chemicals.[citation needed] ...

Baselt R (2011). Disposition of toxic drugs and chemicals in man (9th ed.). Seal Beach, California: Biomedical Publications. pp ... Ravina E (2011). The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs. John Wiley & Sons. p. 24. ISBN ... "Aspirin information from Drugs.com". Drugs.com. Archived from the original on 9 May 2008. Retrieved 8 May 2008.. ... U.S. National Library of Medicine: Drug Information Portal - Aspirin. *CDC - NIOSH Pocket Guide to Chemical Hazards - Acetyl ...

... of title 21 bearing or containing a new animal drug. The term "pesticide" does not include liquid chemical sterilant products ( ... Adjuvants are chemicals added to enhance the performance or efficacy and/or alter the physical properties of the pesticidal ... Under Section 408 of the Federal Food, Drug, and Cosmetic Act (FFDCA), the EPA can also regulate the amount of pesticide ... any nitrogen stabilizer, except that the term "pesticide" shall not include any article that is a "new animal drug" within the ...

"CFR TITLE 21: DRUGS FOR HUMAN USE: PART 341 -- COLD, COUGH, ALLERGY, BRONCHODILATOR, AND ANTIASTHMATIC DRUG PRODUCTS FOR OVER- ... Chemical and physical data. Formula. C10H15N. Molar mass. 149.23 g·mol−1. ... "United States Food and Drug Administration. April 2015. Archived from the original on 18 September 2015. Retrieved 7 March 2016 ... Levomethamphetamine is the active metabolite of the antiparkinson's drug selegiline.[9] Selegiline, a selective monoamine ...

... : Dangers in Everyday Foods, Drugs, and Cosmetics is a book written by Arthur Kallet and F.J. Schlink ... herbicides and other chemicals in food production. Preservatives are particularly criticized, and the increase in canned or ... Jackson, J. "The Ergot Controversy: Prologue to the 1938 Food, Drug, and Cosmetic Act" J Hist Med Allied Sci 1968; XXIII: 248- ... Many people were shocked at the extent of food contamination and drug side-effects, and 100,000,000 Guinea Pigs, along with ...

Izzedine H, Launay-Vacher V, Deybach C, Bourry E, Barrou B, Deray G (November 2005). "Drug-induced diabetes mellitus". Expert ... "Can persistent organic pollutants and plastic-associated chemicals cause cardiovascular disease?". Journal of Internal ... Krentz AJ, Bailey CJ (February 2005). "Oral antidiabetic agents: current role in type 2 diabetes mellitus". Drugs. 65 (3): 385- ... Opinion on Drug Safety. 4 (6): 1097-109. doi:10.1517/14740338.4.6.1097. PMID 16255667.. ...

Chemical pages without DrugBank identifier. *Drugs with no legal status. *All stub articles ... This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.. *v ... Martndale: The Complete Drug Reference, 35th Ed. *^ a b Heinz Reichmann (October 2006). "Budipine in Parkinson's tremor". ... Kornhuber J., Herr B., Thome J., Riederer P. (1995). "The antiparkinsonian drug budipine binds to NMDA and sigma receptors in ...

After 38 weeks, 6% of the people in the three-drug group died while 11% of the people died in the two-drug group. There were ... Chemical and physical data. Formula. C36H47N5O4. ... Viral resistance to the drug leads to the drug becoming useless ... It is recommended that users drink at least 1.5 liters a day when intaking the drug. Drug users must significantly increase ... The Food and Drug Administration (FDA) approved indinavir on March, 1996, making it the eighth antiretroviral drug approved. It ...

De Smet, Peter A.G.M. (December 1997). "The Role of Plant-Derived Drugs and Herbal Medicines in Healthcare". Drugs. 54 (6): 801 ... "Biology-based" as coined by NCCIH may refer to chemicals from a nonbiological source, such as use of the poison lead in ... 2006). "Drug-related hepatotoxicity". New England Journal of Medicine. 354 (7): 731-39. doi:10.1056/NEJMra052270. PMID 16481640 ... The U.S. Food and Drug Administration (FDA), has issued online warnings for consumers about medication health fraud.[157] This ...

Gurib-Fakim, A.. Medicinal plants: traditions of yesterday and drugs of tomorrow.. doi:10.1016/j.mam.2005.07.008. ... Govinden-Soulange, J.; Magan, N.; Gurib-Fakim, A.; Gauvin, A.; Smadja, J.; Kodja, H.. «Chemical composition and in vitro ... Gurib-Fakim, A.; Bourrel, C.; H., Kodja; Govinden, J.. «Chemical Composition of the Essential Oils of Psiadia lithospermifolia ...

IPA also lets researchers search for information on genes, proteins, chemicals, drugs, and reagents. Resulting information can ... All QIAGEN Silicon Valley use the Ingenuity Knowledge Base, which contains biological and chemical interactions and functional ... Food and Drug Administration to use IPA in review of Pharmacogenomics Submissions" (Press release). Ingenuity Systems. June 21 ... US Food and Drug Administration adopts IPA to review pharmacogenomics submissions 2006 - Ingenuity enters into partnerships ...

R. Baselt, Disposition of Toxic Drugs and Chemicals in Man, 8th edition, Biomedical Publications, Foster City, CA, 2008, pp. ...

Koiuszko, S; Bialucha, A; Gospodarek, E (2007). "[The drug susceptibility of penicillin-resistant Streptococcus pneumoniae]". ... "Studies on the chemical nature of the substance inducing transformation of pneumococcal types: induction of transformation by ... or drug-resistant Strepotococcus pneumomoniae (DRSP). Until the year 2000 out of 60,000 yearly cases 40% and out of the 30,000 ...

Raviña, Enrique (2011). "Vinca alkaloids". The evolution of drug discovery: From traditional medicines to modern drugs. John ... Accounts of Chemical Research. 48 (3): 653-662. doi:10.1021/ar500400w.. ... Vinca alkaloids are now produced synthetically and used as drugs in cancer therapy and as immunosuppressive drugs. These ... They are a class of cell cycle-specific cytotoxic drugs that work by inhibiting the ability of cancer cells to divide: Acting ...

... drug occupancy at a purported site of action can be inferred indirectly by competition studies between unlabeled drug and ... Dilworth, Jonathan R.; Pascu, Sofia I. (2018). "The chemistry of PET imaging with zirconium-89". Chemical Society Reviews. 47 ( ... Pharmacokinetics: In pre-clinical trials, it is possible to radiolabel a new drug and inject it into animals. Such scans are ... The uptake of the drug, the tissues in which it concentrates, and its eventual elimination, can be monitored far more quickly ...

Drug sensitization occurs in drug addiction, and is defined as an increased effect of drug following repeated doses (the ... Electrical or chemical stimulation of the rat hippocampus causes strengthening of synaptic signals, a process known as long- ... addictive drug - a drug that is both rewarding and reinforcing. *dependence - an adaptive state associated with a withdrawal ... drug withdrawal - symptoms that occur upon cessation of repeated drug use. *physical dependence - dependence that involves ...

"U.S. Food and Drug Administration (FDA).. *Ebola: What You Need to Know - Scientific American articles related to Ebola; note ... Viral replication triggers high levels of inflammatory chemical signals and leads to a septic state.[38] ... "U.S. Food and Drug Administration (FDA) (Press release). 14 October 2020. Retrieved 14 October 2020.. This article incorporates ... "U.S. Food and Drug Administration (FDA) (Press release). 20 December 2019. Retrieved 22 December 2019.. ...

Another synthetic drug specific to the adenosine A2A receptor subtype is CGS-21680 that has been shown to cause apneas in 14- ... Since many of these neurons express GABA, glutamate, serotonin and adenosine receptors, chemicals custom tailored to bind at ... and chemical signals, such as adenosine, GABA, and glycine. The pre-Bötzinger complex produces two types of breathing rhythms ...

regulation of response to drug. • central nervous system development. • chloride transport. • ion transmembrane transport. • ... chemical synaptic transmission. • regulation of membrane potential. • nervous system process. • synaptic transmission, ...

"Drug Trials Snapshots: Aklief". U.S. Food and Drug Administration (FDA). 11 October 2019. Archived from the original on 19 ... or more are considered to be deep chemical peels.[32] Medium-strength and deep-strength chemical peels are more effective for ... Aslam I, Fleischer A, Feldman S (March 2015). "Emerging drugs for the treatment of acne". Expert Opinion on Emerging Drugs. 20 ... Aslam I, Fleischer A, Feldman S (March 2015). "Emerging drugs for the treatment of acne". Expert Opinion on Emerging Drugs ( ...

Drugs with non-standard legal status. *Chemicals that do not have a ChemSpider ID assigned ... Rituximab Information from the US Food and Drug Administration. *U.S. National Library of Medicine: Drug Information Portal - ... In 2014 Genentech reclassified rituxan as a specialty drug, a class of drugs that are only available through specialty ... "International Drug Price Indicator Guide. Retrieved 28 November 2015.. *^ British national formulary : BNF 69 (69 ed.). British ...

JEL: L65 - Chemicals; Rubber; Drugs; Biotechnology. JEL: L66 - Food; Beverages; Cosmetics; Tobacco. JEL: L67 - Other Consumer ...

Drugs not assigned an ATC code. *ECHA InfoCard ID from Wikidata. *Chemical pages without DrugBank identifier ... Theanine is a chemical that you find in tea and in some mushrooms. Theanine is an amino acid. The chemical theanine can change ... This is a good chemical that fights aging. Theanine helps the immune system. This protects your body against diseases. ...

Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.". Drug Discov Today. 15 (23-24): ... Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State ... of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug ...

... by drugs known as neurokinin type 1 antagonists (also termed: SP antagonists, or tachykinin antagonists.) One such drug is ... "Blood chemicals link' to eczema". Health. BBC NEWS. 2007-08-26. Retrieved 2008-11-01.. ... Muñoz M, Rosso M, Coveñas R (Jun 2011). "The NK-1 receptor: a new target in cancer therapy". Current Drug Targets. 12 (6): 909- ... SP initiates expression of almost all known immunological chemical messengers (cytokines).[19][20][21] Also, most of the ...

"The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals (English)"; date o publication: 1996; page: 1613. ...

... Information from the US Food and Drug Administration. *U.S. National Library of Medicine: Drug Information Portal - ... Chemical and physical data. Formula. C6416H9874N1688O1987S44. ... Patents on the drug in expired in Europe in February 2013 and ... In 2014 Genentech reclassified rituxan as a specialty drug, a class of drugs that are only available through specialty ... "International Drug Price Indicator Guide. Retrieved 28 November 2015.. *^ British national formulary : BNF 69 (69 ed.). British ...

Aminorex a drug bearing an oxazoline ring. References[edit]. *^ a b Wenker, H. (1938). "Syntheses from Ethanolamine. V. ... Controlled reduction of oxazolium salts". Journal of the American Chemical Society. 110 (10): 3238-3246. doi:10.1021/ ... "Advanced Drug Delivery Reviews. 59 (15): 1504-1520. doi:10.1016/j.addr.2007.08.018. PMID 17904246.. ... Oxazoline is a five-membered heterocyclic chemical compound containing one atom each of oxygen and nitrogen. It was likely ...

"Drug Discov Today 15 (23-24): 1052-7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. edit ... manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi: ... 2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100-7. PMID ... "Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices". Chem Inf. Comput. Sci. 41: 1488-1493. PMID ...

An alcoholic drink (or alcoholic beverage) is a drink that contains the recreational drug ethanol, a type of alcohol produced ... According to a study published in the Proceedings of the National Academy of Sciences, chemical analysis of the residue ... Alcohol is one of the most widely used recreational drugs in the world, with about 33% of people being current drinkers.[4] As ... "Processing and chemical constituents of Pu-erh tea: A review." Food Research International 53.2 (2013): 608-618. ...

"Synthroid (Levothyroxine Sodium) Drug Information: Uses, Side Effects, Drug Interactions and Warnings". RxList. Archived from ... Its chemical nature and physiologic activity". J. Am. Med. Assoc. 64 (25): 2042-2043. doi:10.1001/jama.1915.02570510018005.. ... "International Drug Price Indicator Guide. Retrieved 8 December 2016.. *^ Hamilton, Richart (2015). Tarascon Pocket ... "Levothyroxine (Lexi-Drugs)". LexiComp. Archived from the original on 29 September 2014. Retrieved 20 April 2014.. ...

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