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*  GroES
The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL. GroES exists as a ring- ... Of these, six were lost within ten days of ovulation (43% rate of early conceptus loss). Use of EPF has been proposed to ... Lee KH, Kim HS, Jeong HS, Lee YS (October 2002). "Chaperonin GroESL mediates the protein folding of human liver mitochondrial ... Lee KH, Kim HS, Jeong HS, Lee YS (2002). "Chaperonin GroESL mediates the protein folding of human liver mitochondrial aldehyde ...
*  HSP60
Alternate Names: 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, HuCHA60, Mitochondrial matrix protein ... this is not the case with chaperonins". It has been found that many anti-chaperonin antibodies exist and are associated with ... "generated by a human host after exposure to bacterial chaperonin 60 proteins" can cross-react with human chaperonin 60 proteins ... Chaperonin 10 aids HSP60 in folding by acting as a dome-like cover on the ATP active form of HSP60. This causes the central ...
*  TCP-1/cpn60 chaperonin family
... is a family of evolutionarily related proteins. This family includes members from the HSP60 ... This chaperonin complex is essential for the correct folding and assembly of polypeptides into oligomeric structures, of which ... The 60 kDa form of chaperonin is the immunodominant antigen of patients with Legionnaire's disease, and is thought to play a ... These 'helper' molecules are referred to as molecular chaperones, a subfamily of which are the chaperonins, which include 10 ...
*  BBS10
2007). "Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin- ... "BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus". Nat. Genet. 38 (5): 521-4. doi:10.1038/ ... Bardet-Biedl syndrome 10, also known as BBS10 is a human gene. The Bardet-Biedl syndrome 10 protein has distant sequence ... homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or ...
*  Non-chaperonin molecular chaperone ATPase
... (EC 3.6.4.10, molecular chaperone Hsc70 ATPase) is an enzyme with systematic name ATP ... Non-chaperonin molecular chaperone ATPase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... phosphate These enzymes perform many functions that are similar to those of chaperonins. Chaperone (protein) Sadis, S.; ...
*  Archaea
Trent JD; Kagawa HK; Yaoi T; Olle E; Zaluzec NJ (1997). "Chaperonin filaments: the archaeal cytoskeleton?". Proceedings of the ... making up about one in ten of all the prokaryotes in the human gut. In termites and in humans, these methanogens may in fact be ... Retrieved 2006-01-10. Dalrymple, G. Brent (2001). "The age of the Earth in the twentieth century: a problem (mostly) solved". ... 94 (10): 5383-8. Bibcode:1997PNAS...94.5383T. doi:10.1073/pnas.94.10.5383. PMC 24687 . PMID 9144246. Hixon, W.G.; Searcy, D.G ...
*  GroEL
Binding of GroES to the open cavity of the chaperonin induces the individual subunits of the chaperonin to rotate such that the ... GroEL belongs to the chaperonin family of molecular chaperones, and is found in a large number of bacteria. It is required for ... Chaperonin Heat shock protein GRCh38: Ensembl release 89: ENSG00000144381 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Horwich AL, Fenton WA, Chapman E, Farr GW (2007). "Two families of chaperonin: physiology and mechanism". Annu. Rev. Cell Dev. ...
*  Prefoldin
... bonds specifically to cytosolic chaperonin protein. This complex of prefoldin and chaperonin then forms molecules of ... due to its high affinity for the chaperonin molecule. Once the prefoldin is in contact with the chaperonin protein, it loses ... For example, the prefoldin that is used in the formation of actin also transfers α or β tubulin to a cytosolic chaperonin. The ... A prefoldin molecule works as a transfer protein in conjunction with a molecule of chaperonin to form a chaperone complex and ...
*  TBCA
This gene encodes chaperonin cofactor A. GRCh38: Ensembl release 89: ENSG00000171530 - Ensembl, May 2017 GRCm38: Ensembl ... "Entrez Gene: TBCA tubulin folding cofactor A". Lewis SA, Tian G, Vainberg IE, Cowan NJ (1996). "Chaperonin-mediated folding of ... 10 (10): 1546-60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152. Guasch A, Aloria K, Pérez R, et al. (2002). "Three- ...
*  Dihydrofolate reductase
"Protein folding in the central cavity of the GroEL-GroES chaperonin complex". Nature. 379 (6564): 420-6. doi:10.1038/379420a0. ... "Protein folding in the central cavity of the GroEL-GroES chaperonin complex". Nature. 379 (6564): 420-6. doi:10.1038/379420a0. ... 4 (10): 2010-6. doi:10.1128/mcb.4.10.2010. PMC 369017 . PMID 6504041. Smith SL, Patrick P, Stone D, Phillips AW, Burchall JJ ( ... 50 (10): 3435-43. doi:10.1128/AAC.00386-06. PMC 1610094 . PMID 17005826. Chan DC, Fu H, Forsch RA, Queener SF, Rosowsky A (June ...
*  CCT7
"Entrez Gene: CCT7 chaperonin containing TCP1, subunit 7 (eta)". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M ... This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the ... Hynes G, Celis JE, Lewis VA, Carne A, U S, Lauridsen JB, Willison KR (Nov 1996). "Analysis of chaperonin-containing TCP-1 ... Yokota S, Yanagi H, Yura T, Kubota H (Sep 2001). "Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content ...
*  Phosducin-like
2002). "Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex". Proc. Natl. Acad. Sci. U.S.A. ... 10 (11): 1788-95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863. Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward ... of G protein betagamma subunits by protein kinase CK2-phosphorylated phosducin-like protein and the cytosolic chaperonin ...
*  Von Hippel-Lindau binding protein 1
It is also involved in transporting nascent polypeptides to cytosolic chaperonins for post-translational folding. VBP1 is a 197 ... "NiceProt report: P61758 (Prefoldin 3, human)". 2007-07-10. Retrieved 2007-07-17. Brinke A, Green PM & Giannelli F (1997). " ...
*  MKKS
McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin is a protein that in humans is encoded by the MKKS gene. This gene ... 2005). "MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel ... 2000). "Mutation of a gene encoding a putative chaperonin causes McKusick-Kaufman syndrome". Nat. Genet. 25 (1): 79-82. doi: ... 10 (11): 1788-95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863. Beales PL, Katsanis N, Lewis RA, et al. (2001). "Genetic ...
*  Electrospray ionization
Sobott; Robinson (2004). "Characterising electrosprayed biomolecules using tandem-MS-the noncovalent GroEL chaperonin assembly ... 18 (10): 1891-9. doi:10.1016/j.jasms.2007.07.022. PMID 17766144. Gabelica V, Vreuls C, Filée P, Duval V, Joris B, Pauw ED (2002 ... 2002-10-09. Retrieved 2011-04-02. Pozniak BP, Cole RB (2007). "Current Measurements within the Electrospray Emitter". JASMS. 18 ... 40 (10): 1261-75. Bibcode:2005JMSp...40.1261T. doi:10.1002/jms.922. PMID 16237663. Konermann, L; Douglas, DJ (1998). " ...
*  CCT2 (gene)
"Entrez Gene: CCT2 chaperonin containing TCP1, subunit 2 (beta)". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault ... This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ... Yokota S, Yanagi H, Yura T, Kubota H (Sep 2001). "Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content ... Hynes GM, Willison KR (Jun 2000). "Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding ...
*  Hsp90
Xu Z, Horwich AL, Sigler PB (August 1997). "The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex". ... 5 (10): 761-72. doi:10.1038/nrc1716. PMID 16175177. Kim YS, Alarcon SV, Lee S, Lee MJ, Giaccone G, Neckers L, Trepel JB (2009 ... 59 (10): 1640-8. doi:10.1007/PL00012491. PMID 12475174. Imai J, Maruya M, Yashiroda H, Yahara I, Tanaka K (July 2003). "The ... 10 (6): 1307-18. doi:10.1016/S1097-2765(02)00785-2. PMID 12504007. Marcu MG, Chadli A, Bouhouche I, Catelli M, Neckers LM ( ...
*  Structural gene
"Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 ... 57 (10): 2259-2261. doi:10.1099/ijs.0.64915-0. Hebert, Paul D. N.; Cywinska, Alina; Ball, Shelley L.; deWaard, Jeremy R. (2003- ... 107 (10): 2417-2424. doi:10.1002/cncr.22265. ISSN 0008-543X. PMID 17048249. Son, Dong Ju; Kumar, Sandeep; Takabe, Wakako; Kim, ... 14 (10): 630-642. doi:10.1038/nrm3658. ISSN 1471-0072. PMC 4340576 . PMID 24026055. Koll, H.; Guiard, B.; Rassow, J.; Ostermann ...
*  CCT5 (gene)
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ... Yokota S, Yanagi H, Yura T, Kubota H (Sep 2001). "Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content ... Roobol A, Holmes FE, Hayes NV, Baines AJ, Carden MJ (Apr 1995). "Cytoplasmic chaperonin complexes enter neurites developing in ... Liou AK, Willison KR (Jul 1997). "Elucidation of the subunit orientation in CCT (chaperonin containing TCP1) from the subunit ...
*  Major sperm protein
Despite only 11% of sequence similarity, MSP and the N-terminus of the bacterial P-pilus associated chaperonin PapD share a ... 18 (10): 705-14. doi:10.1016/j.cub.2008.04.043. PMC 2613949 . PMID 18472420. Kuwabara PE (January 2003). "The multifaceted C. ... It increases the contraction rate from 10-13 to around 19 contractions per minute. The importance of these contractions is ...
*  PACRG
... and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses ... 18 (6): 404-10. doi:10.1016/j.smim.2006.07.005. PMID 16973374. Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of ... 278 (51): 51901-10. doi:10.1074/jbc.M309655200. PMID 14532270. Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence ...
*  CCT4
"Entrez Gene: CCT4 chaperonin containing TCP1, subunit 4 (delta)". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault ... "Eukaryotic type II chaperonin CCT interacts with actin through specific subunits". Nature. 402 (6762): 693-6. doi:10.1038/45294 ... "Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin". Journal of Structural ... "Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin". Current Biology. 4 ( ...
*  CCT6A
"Entrez Gene: CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, ... This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ... Yokota S, Yanagi H, Yura T, Kubota H (2001). "Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a ... "Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA ...
*  PFDN2
1998). "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin". Cell. 93 (5): 863-73. doi:10.1016/ ... 10 (10): 1546-60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152. Strausberg RL, Feingold EA, Grouse LH, et al. (2003). " ...
*  Macromolecular crowding
Martin J, Hartl FU (February 1997). "The effect of macromolecular crowding on chaperonin-mediated protein folding". Proc. Natl ... 20: 3-10. doi:10.1016/j.cocis.2014.12.003. Sapir, L; Harries, D. (2015). "Macromolecular Stabilization by Excluded Cosolutes: ... 26 (10): 597-604. doi:10.1016/S0968-0004(01)01938-7. PMID 11590012. Zimmerman SB, Trach SO (December 1991). "Estimation of ... 38 (10): 1911-21. PMID 9331254. Steadman BL, Trautman PA, Lawson EQ, et al. (December 1989). "A differential scanning ...
*  Yale School of Medicine
... uncovered the action of chaperonins in his study of protein folding James D. Jamieson (1973-), Cell biologist, established the ... 10″N 72°56′10″W / 41.3027°N 72.936°W / 41.3027; -72.936. ...