Bromisoval
Arai, A.; Sato, M.; Hozumi, I.; Matsubara, N.; Tanaka, K.; Soma, Y.; Adachi, T.; Tsuji, S. (1997). "Cerebellar Ataxia and ... Dystonic posture and cerebellar ataxia due to nonsteroidal anti-inflammatory drug abuse" (pdf). Internal Medicine. Tokyo, Japan ...
ARHGAP26
... autoantibody-associated cerebellar ataxia". J Neuroinflammation. 10 (1): 7. doi:10.1186/1742-2094-10-7. PMC 3549891. PMID ... associated with subacute cerebellar ataxia: immunological characterization". J Neuroinflammation. 7 (1): 21. doi:10.1186/1742- ... autoantibodies to ARHGAP26 have been implicated in autoimmune cerebellar ataxia. ARHGAP26 has been shown to interact with PKN3 ... "Anti-Ca/anti-ARHGAP26 antibodies associated with cerebellar atrophy and cognitive decline". J. Neuroimmunol. 267 (1-2): 102-4. ...
Non-celiac gluten sensitivity
2016). "Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias". Cerebellum (Review). 15 (2): 213-32. doi:10.1007/s12311 ... A part of people with gluten-related neuropathy or ataxia appears not to be able to tolerate even the traces of gluten allowed ... The death of neurons in the cerebellum in ataxia is the result of gluten exposure and is irreversible. Early treatment with a ... NCGS is also linked to a wide spectrum of neurological and psychiatric disorders, including ataxia, schizophrenia, epilepsy, ...
Gluten-related disorders
2016). "Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias". Cerebellum (Review). 15 (2): 213-32. doi:10.1007/s12311 ... Gluten ataxia accounts for 40% of ataxias of unknown origin and 15% of all ataxias. Less than 10% of people with gluten ataxia ... Gluten ataxia is an autoimmune disease triggered by the ingestion of gluten. With gluten ataxia, damage takes place in the ... cerebellar ataxia, hypertransaminasemia and peripheral neuropathy. As previously mentioned, CD very frequently may be ...
Purkinje cell
... such as the cerebellar type of multiple system atrophy or sporadic ataxias. Gluten ataxia is an autoimmune disease triggered by ... It accounts for 40% of ataxias of unknown origin and 15% of all ataxias. The neurodegenerative disease spinocerebellar ataxia ... The genetic conditions ataxia telangiectasia and Niemann Pick disease type C, as well as cerebellar essential tremor, involve ... 2016). "Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias". Cerebellum (Review). 15 (2): 213-32. doi:10.1007/s12311 ...
Gluten
2016). "Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias". Cerebellum (Review). 15 (2): 213-32. doi:10.1007/s12311 ... Gluten ataxia accounts for 40% of ataxias of unknown origin and 15% of all ataxias. Less than 10% of people with gluten ataxia ... Gluten ataxia is an autoimmune disease triggered by the ingestion of gluten. With gluten ataxia, damage takes place in the ... People with gluten ataxia usually present gait abnormality or incoordination and tremor of the upper limbs. Gaze-evoked ...
Oculomotor apraxia
Le Ber, I.; Brice, A.; Dürr, A. (2005). "New autosomal recessive cerebellar ataxias with oculomotor apraxia". Current Neurology ... These are ataxia with oculomotor apraxia type 1 (AOA1), ataxia with oculomotor apraxia 2 (AOA2), and ataxia telangiectasia. ... It is an autosomal recessive cerebellar ataxia (ARCA) associated with hypoalbuminemia and hypercholesterolemia. Mutations in ... Ataxia-oculomotor apraxia type 2 (AOA2), also known as spinocerebellar ataxia with axonal neuropathy type 2, has its onset ...
Cognitive reserve
Mitoma H, Manto M, Hampe CS (2017). "Immune-mediated cerebellar ataxias: from bench to bedside". Cerebellum & Ataxias. 4: 16. ... Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders". Cerebellum (London, England). 19 (1): 131-153. doi: ... Cerebellar circuitry is a site of multiple forms of neuronal plasticity, a factor playing a major role in terms of brain ... Revisiting the Symptoms and Signs of Cerebellar Syndrome". Cerebellum. 15 (3): 369-91. doi:10.1007/s12311-015-0687-3. PMC ...
ADCK3
2008). "CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures". Am. J. Hum. Genet. 82 (3): 623- ... 2008). "ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency". Am. J. ...
Aprataxin
2003). "Cerebellar ataxia with oculomotor apraxia type 1: clinical and genetic studies". Brain. 126 (Pt 12): 2761-72. doi: ... 1989). "Ataxia-ocular motor apraxia: a syndrome mimicking ataxia-telangiectasia". Ann. Neurol. 24 (4): 497-502. doi:10.1002/ana ... GeneReviews/NCBI/NIH/UW entry on Ataxia with Oculomotor Apraxia Type 1 OMIM entries on Ataxia with Oculomotor Apraxia Type 1 ... 2005). "The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break ...
Pierre Marie
... with cerebellar ataxia. "Marie-Foix-Alajouanine syndrome": cerebellar ataxia of the cerebellum in the elderly; usually due to ... "Marie's ataxia": an hereditary disease of the nervous system, ...
Heinrich Frenkel
Frenkel achieved great success with therapeutic exercises for cerebellar ataxia and ataxia. This success eventually attracted ... He was the author of Die Therapie ataktischer Bewegungsstörungen, a treatise on treatment of tabetic ataxia by means of ...
PLEKHG4
2006). "16q-linked autosomal dominant cerebellar ataxia: a clinical and genetic study". J. Neurol. Sci. 247 (2): 180-6. doi: ... 2007). "Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia". J. Hum. Genet. 52 (8): 643-9. doi ... 2005). "Fine mapping of 16q-linked autosomal dominant cerebellar ataxia type III in Japanese families". Neurogenetics. 5 (4): ... "An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the ...
Contactin 1
"Ataxia and abnormal cerebellar microorganization in mice with ablated contactin gene expression". Neuron. 24 (3): 739-50. doi: ...
Ulas family
The affected siblings have a form of non-progressive congenital cerebellar ataxia. The brain impairments include cerebellar ... However, they do not show the poor coordination of hands, speech, and eye movements often found in cerebellar ataxia. The four ... May 2006). "Cerebellar hypoplasia and quadrupedal locomotion in humans as a recessive trait mapping to chromosome 17p". J. Med ...
Ataxia
Dystaxia is a mild degree of ataxia. The term cerebellar ataxia is used to indicate ataxia due to dysfunction of the cerebellum ... "Redefining cerebellar ataxia in degenerative ataxias: lessons from recent research on cerebellar systems". Journal of Neurology ... Although ataxia is not present with all cerebellar lesions, many conditions affecting the cerebellum do produce ataxia. People ... GAD antibodies related ataxia is part of the group called immune-mediated cerebellar ataxias. The antibodies induce a ...
PRICKLE1-related progressive myoclonus epilepsy with ataxia
"An autosomal recessive cerebellar ataxia syndrome with upward gaze palsy, neuropathy, and seizures". Neurology. 64 (1): 142-144 ... myoclonus epilepsy with ataxia is a very rare genetic disorder which is characterized by myoclonic epilepsy and ataxia. Ataxia ... "A distinct autosomal recessive ataxia maps to chromosome 12 in an inbred family from Jordan". Brain & Development. 28 (6): 353- ... "PRICKLE1-related progressive myoclonus epilepsy with ataxia: MedlinePlus Genetics". medlineplus.gov. Retrieved 2022-06-06. ...
AFG3L2
"Spinocerebellar ataxia type 28: A novel autosomal dominant cerebellar ataxia characterized by slow progression and ... a novel form of autosomal dominant cerebellar ataxia on chromosome 18p11.22-q11.2". Brain. 129 (Pt 1): 235-242. doi:10.1093/ ... of European autosomal dominant cerebellar ataxias". Human Mutation. 31 (10): 1117-1124. doi:10.1002/humu.21342. PMID 20725928. ... This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia ...
Cereblon
"Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency". Proc. Natl. Acad. Sci. U.S.A. ...
Short-term effects of alcohol consumption
Mitoma H, Manto M, Shaikh AG (August 2021). "Mechanisms of Ethanol-Induced Cerebellar Ataxia: Underpinnings of Neuronal Death ... Another classic finding of alcohol intoxication is ataxia, in its appendicular, gait, and truncal forms. Appendicular ataxia ... Ataxia causes the observation that drunk people are clumsy, sway back and forth, and often fall down. It is presumed to be due ... Truncal ataxia results in postural instability; gait instability is manifested as a disorderly, wide-based gait with ...
Ninein
"Spectrum of centrosome autoantibodies in childhood varicella and post-varicella acute cerebellar ataxia". BMC Pediatrics. 3: 11 ...
Lateral medullary syndrome
The damage to the cerebellum or the inferior cerebellar peduncle can cause ataxia. Damage to the hypothalamospinal fibers ... The ischemia is a result of a blockage most commonly in the vertebral artery or the posterior inferior cerebellar artery. ... It is the clinical manifestation resulting from occlusion of the posterior inferior cerebellar artery (PICA) or one of its ... Lateral medullary syndrome is also called Wallenberg's syndrome, posterior inferior cerebellar artery (PICA) syndrome and ...
Progressive supranuclear palsy
Cerebellar ataxia as the predominant early presenting feature is increasingly recognized as a very rare subtype of PSP (PSP-C) ... "Early clinical features of patients with progressive supranuclear palsy with predominant cerebellar ataxia". Parkinsonism Relat ... which is associated with severe neuronal loss with gliosis and higher densities of coiled bodies in the cerebellar dentate ...
Glutamate decarboxylase
"Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia". Orphanet Journal ... Cerebellar Purkinje cells also reported a 40% downregulation, suggesting that affected cerebellar nuclei may disrupt output to ... "Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias". Journal of Immunology Research. 2017 ... Epitope recognition contributes to cerebellar involvement. Reduced GABA levels increase glutamate levels as a consequence of ...
Contactin 4
It has also been associated with cerebellar degeneration in spinocerebellar ataxia type 16. GRCh38: Ensembl release 89: ...
Spinocerebellar ataxia type 1
... and other known types of ataxia, calling the syndrome hereditary cerebellar ataxia, though it became known Marie's ataxia. ... Holmes G (1908). "An Attempt to Classify Cerebellar Disease, with a Note on Marie's Hereditary Cerebellar Ataxia". Brain. 30 (4 ... "Spinocerebellar Ataxia Type 1 , The Ataxia Center , The University of Chicago". ataxia.uchicago.edu. University of Chicago ... impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 ...
GRID2
"Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans". Neurology. 81 (16): 1378-86. ... and lower motor neuron involvement whereas a homozygous biallelic deletion leads to a syndrome of cerebellar ataxia with marked ... "A homozygous deletion in GRID2 causes a human phenotype with cerebellar ataxia and atrophy". Journal of Child Neurology. 28 (7 ... Yuzaki M (Nov 2013). "Cerebellar LTD vs. motor learning-lessons learned from studying GluD2". Neural Networks. 47: 36-41. doi: ...
SEPP1
August 2021). "Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs". PLOS Genetics. 17 (8): ... may develop cerebellar ataxia phenotypes. SEPP1 and neural precursor cell levels in mouse brains increase post-exercise. Mice ...
Paraneoplastic cerebellar degeneration
Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, ... Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma ... Therefore, newly developing cerebellar ataxia should always prompt proper diagnostic measures to exclude PCD. Tumor removal is ... the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ ...
Phytanic acid
This frequently leads to peripheral polyneuropathy, cerebellar ataxia, retinitis pigmentosa, anosmia, and hearing loss. In ...
Conorenal syndrome
... cerebellar ataxia and skeletal abnormalities". Am. J. Med. 49 (4): 556-62. doi:10.1016/S0002-9343(70)80051-1. PMID 4991086. ... or ataxia (an inability to coordinate muscular movements). In 1995, a group led by Mendley studied two siblings and determined ...
John E. Flint
Both died young due to the inherited degenerative condition cerebellar ataxia. Sir George Goldie and the making of Nigeria. ...
CAPOS syndrome
... early-onset reoccurring cerebellar ataxia and progressive optic atrophy accompanied by sensorineural deafness. "Cerebellar ... "Cerebellar ataxia-areflexia-pes cavus-optic atrophy-sensorineural hearing loss syndrome". www.ebi.ac.uk. Archived from the ... "Cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorinural hearing loss - About the Disease - Genetic and Rare ... "Orphanet: Cerebellar ataxia areflexia pes cavus optic atrophy sensorineural hearing loss syndrome". www.orpha.net. Archived ...
RFC1
February 2020). "Cerebellar ataxia, neuropathy, vestibular areflexia syndrome due to RFC1 repeat expansion". Brain. 143 (2): ... gene causes cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS). Within the poly(A) tail of an AluSx3 ... isolate cerebellar ataxia. Due to a diagnostic overlap with CANVAS, researchers have also investigated the presence of RFC1 ... Biallelic "AAGGG" repeat expansion is also reported in a high number of sporadic cases of late-onset ataxia, isolate sensory ...
SCARB1
Skre H, Berg K (1974). "Cerebellar ataxia and total albinism: a kindred suggesting pleitotropism or linkage". Clinical Genetics ...