All centromeres are associated with centromere protein A (CENPA). CENPA also been widely studied as an important player in ... Centromere repositioning and evolutionary new centromeres are also thought to be involved in speciation as incompatibility ... Sullivan, B. A. (2013-01-01). "Centromeres". In Lane, M. Daniel (ed.). Centromeres A2 - Lennarz, William J. Waltham: Academic ... Another striking thing in centromere evolution is that while centromere function is conserved among all eukaryotes the ...

... acen Centromere. var: Variable region; stalk: Stalk. Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker ...

The centromere of chromosome 14 is positioned approximately at position 17.2 Mbp. The following are some of the gene count ... acen Centromere. var: Variable region; stalk: Stalk. Campo E (2003). "Genetic and molecular genetic studies in the diagnosis of ...

... acen Centromere. var: Variable region; stalk: Stalk. Gilbert F, Kauff N (2000). "Disease genes and chromosomes: disease maps of ...

... acen Centromere. var: Variable region; stalk: Stalk. Murphy WJ, Fronicke L, O'Brien SJ, Stanyon R (2003). "The Origin of Human ... Centromere protein L CENPF (1q41) CHTOP: Chromatin target of prmt1 CNIH4: cornichon homolog 4 CNST: Consortin CREG1: Cellular ...

... acen Centromere. var: Variable region; stalk: Stalk. Wikimedia Commons has media related to Human chromosome 20. National ...

There are six known antigens, which are all associated with the centromere; CENP-A to CENP-F. CENP-A is a 17kDa histone H3-like ... The centromere pattern shows multiple nuclear dots in interphase and mitotic cells, corresponding to the number of chromosomes ... Anti-centromere antibodies are associated with limited cutaneous systemic sclerosis, also known as CREST syndrome, primary ... This allows the detection of antibodies to mitosis-specific antigens, such as centromere antibodies. They also allow ...

Centromeres are another example of functional noncoding DNA sequences that have been known for almost half a century and it's ... Centromeres are the sites where spindle fibers attach to newly replicated chromosomes in order to segregate them into daughter ... Most of the highly repetitive DNA is found in centromeres and telomeres (see above) and most of it is functional although some ... In humans, for example, the sequences of all 24 centromeres have been determined and they account for about 6% of the genome. ...

"2014 Centromere Biology Conference GRC". www.grc.org. Workshops, EMBO Courses &. "Comparative genomics of eukaryotic microbes: ... Sanyal, K; Carbon, J (1 October 2002). "The CENP-A homolog CaCse4p in the pathogenic yeast Candida albicans is a centromere ... USA to work in the laboratory of John Carbon on the discovery of centromeres in Candida albicans. He joined JNCASR in 2005. He ... Centromere and Kinetochore: Essential Components for Chromosome Segregation. Wiley-VCH Verlag GmbH & Co. KGaA. pp. 259-288. doi ...

Aurora B is found at the centromere, between the two kinetochores. In the absence of tension, Aurora B can phosphorylate ... However, sometimes the kinetochores are found on the same side of the centromere, and this error cannot be corrected ... Lampson, Michael A.; Cheeseman, Iain M. (2011). "Sensing centromere tension: Aurora B and the regulation of kinetochore ... Khodjakov, Alexey; Pines, Jonathon (2010). "Centromere tension: a divisive issue". Nature Cell Biology. 12 (10): 919-923. doi: ...

Normally a chromosome has just one centromere, but in chromosome 2 there are remnants of a second centromere. The presence of ...

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid ... August 2001). "CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells ... Centromere protein H is a protein that in humans is encoded by the CENPH gene. It is involved in the assembly of kinetochore ... "Entrez Gene: CENPH centromere protein H". McClelland SE, Borusu S, Amaro AC, Winter JR, Belwal M, McAinsh AD, Meraldi P ( ...

Centromere protein C 1 is a protein that in humans is encoded by the CENPC1 gene. Centromere protein C 1 is a centromere ... 2007). "Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere". Genome Res. 17 ( ... 2002). "Mutational analysis of the central centromere targeting domain of human centromere protein C, (CENP-C)". Exp. Cell Res ... "Entrez Gene: CENPC1 centromere protein C 1". Human CENPC genome location and CENPC gene details page in the UCSC Genome Browser ...

Telomeres and centromeres typically contain few genes but are important for the function and stability of chromosomes. An ... Pidoux AL, Allshire RC (March 2005). "The role of heterochromatin in centromere function". Philosophical Transactions of the ...

Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene. This gene encodes a ... Starr DA, Williams BC, Li Z, Etemad-Moghadam B, Dawe RK, Goldberg ML (Oct 1997). "Conservation of the centromere/kinetochore ... The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to ...

Reinhart, BJ; Bartel, DP (13 September 2002). "Small RNAs correspond to centromere heterochromatic repeats". Science. 297 (5588 ...

Finally, the interstitial regions are the parts of the p and q regions that are close to neither the centromere nor the ... Whereas if the chromosome is isobrachial (centromere at centre and arms of equal length), the p and q system is meaningless. At ... The complexes containing the duplicated DNA molecules, the sister chromatids, are attached to each other by the centromere( ... These are listed as follows: Chromatids Arms Centromere Kinetochore Telomere Sub telomere satellite chromosome or trabant. NOR ...

The centromere is the point of attachment for the mitotic apparatus Deletions, duplications and translocations can produce a ... Monocentric centromeres are the most common structure on highly repetitive DNA in plants and animals. Monocentric chromosomes ... The monocentric chromosome is a chromosome that has only one centromere in a chromosome and forms a narrow constriction. ... In monocentric chromosomes there is one primary constriction and the centromere its CenH3 loci at this location. Holocentric ...

Microtubules project from opposite ends of the cell, attach to the centromeres, and align the chromosomes centrally within the ... The two chromatids are joined at the centromere. Gene transcription ceases during prophase and does not resume until late ... A kinetochore is a proteinaceous microtubule-binding structure that forms on the chromosomal centromere during late prophase. A ... Chromosome duplication results in two identical sister chromatids bound together by cohesin proteins at the centromere. When ...

Malik, Harmit S. (2009). "The centromere-drive hypothesis: a simple basis for centromere complexity". Progress in Molecular and ... Centromere-drive describes an evolutionary process in which centromeric repeats expand, which results in the recruitment of ... Chang, Ching-Ho; Malik, Harmit S. (2021-04-22). "Putting the brakes on centromere drive in Mimulus". PLOS Genetics. 17 (4): ... Working with Steven Henikoff, Malik developed the concept of centromere-drive, a mechanism that explains the unusual genetic ...

When Aurora B's function is disrupted, MCAK ability to locate centromeres, which play a critical role in separation of ... Kinesin-13 MCAK (Mitotic Centromere-Associated Kinesin) is a KRP that is involved in resolving errors during mitosis involving ... "Aurora B regulates MCAK at the mitotic centromere". Developmental Cell. 6 (2): 253-68. doi:10.1016/s1534-5807(04)00025-5. PMID ...

Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene. CENPA is a histone H3 ... December 2018). "Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle". Current ... Obuse C, Yang H, Nozaki N, Goto S, Okazaki T, Yoda K (February 2004). "Proteomics analysis of the centromere complex from HeLa ... Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL, Choo KH (November 2000). "Survivin and the inner centromere protein ...

"Silencing of genes flanking the P1 plasmid centromere". Science. 283 (5401): 546-9. Bibcode:1999Sci...283..546R. doi:10.1126/ ...

In general, clusters nearer the centromere replicate earlier. Fine structure analysis of chromosomal origins of replication is ...

Each row is vertically aligned at centromere level. It shows 22 homologous autosomal chromosome pairs, both the female (XX) and ... Robertsonian translocation: An entire chromosome has attached to another at the centromere - in humans, these only occur with ... Isochromosome: Formed by the mirror image copy of a chromosome segment including the centromere. Chromosome instability ...

DNA sequences and localized them in centromeres. They were homologous to simian, but not simpler mouse centromere repeats. ... By charting the movement of the X chromosome in large neurons in epilepsy, and the movement of centromeres during post-mitotic ... These late replicating sequences, that contain few if any genes, define all human chromosome centromeres as shown by the ... As in other mammalian cells, centromeres are critical for proper segregation of chromosomes between two new daughter cells ...

"Aurora B regulates MCAK at the mitotic centromere". Developmental Cell. 6 (2): 253-268. doi:10.1016/s1534-5807(04)00025-5. PMID ... "Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases". The ...

Godward MB (April 1954). "The 'Diffuse' Centromere or Polycentric Chromosomes in Spirogyra". Annals of Botany. 18 (2): 143-144 ... In genetics, a polycentric chromosome is any chromosome featuring multiple centromeres. Polycentric chromosomes are produced by ... 2012-06-21). "Stretching the rules: monocentric chromosomes with multiple centromere domains". PLOS Genetics. 8 (6): e1002777. ...

The centromeres have two types of structural components, both of which are found only in the centromeres: Large arrays of CentC ... Kinetochores contain RNA originating from centromeres. Centromere regions can become inactive, and can continue in that state ... Centromeres can accidentally shrink during division and still function, although it is thought this will fail if it shrinks ... Birchler, James A.; Han, Fangpu (December 1, 2009). "Maize Centromeres: Structure, Function, Epigenetics". Annual Review of ...

Centromere protein O is a protein that in humans is encoded by the CENPO gene. CENPO is involved in cell proliferation and cell ... "Entrez Gene: CENPO centromere protein O". Hewitt, Chelsee A.; Ling, King-Hwa; Merson, Tobias D.; Simpson, Ken M.; Ritchie, ... 2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a ... 2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human ...