*Chlormezanone

Sterling Drug Inc., US 3082209 (1958). Surrey, A. R.; Webb, W. G.; Gesler, R. M. (1958). "Central Nervous System Depressants. ... Seeling A, Oelschl├Ąger H, Rothley D (2000). "Important pharmaceutical-chemical characteristics of the central muscle relaxant ... Cleavage and biotransformation of the central muscle relaxant chlormezanone]". Pharmazie. 53 (9): 620-4. PMID 9770210. Gautier ...

*Carbamic acid

2004). "Central Nervous System Depressant". Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry. ...

*Corvalol

Phenobarbital is a central nervous system depressant. According to the Farmak product label of Colvalol oral solution, the ... Symptoms of overdose include central nervous system depression, confusion, dizziness, ataxia, and somnolence. In serious cases ... Corvalol may increase CNS depressant effect of other sedatives and hypnotics. Corvalol belongs to the sedative-hypnotic ... nervous asthma, hysterical states, excitability, hypochondria, headaches, migraine, menstrual cramps and symptoms associated ...

*Date rape drug

Gamma-hydroxybutyrate (GHB) is a central nervous system depressant. It has no odor, tastes salty, but is detectable when mixed ...

*Anticonvulsant

Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum ... Benzodiazepines act as a central nervous system depressant. The relative strength of each of these properties in any given ... Next to the voltage-gated sodium channels and components of the GABA system, their targets include GABAA receptors, the GAT-1 ... and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell ...

*Depressant

They do produce central nervous system depression, however, they also excite certain areas of the central nervous system. To ... Central nervous system depressant Narcotic Inhalant "Depressant - Definition". Princeton WordNet. Retrieved 28 December 2013. " ... Combining multiple depressants can be very dangerous because the central nervous system's depressive properties have been ... when combined with other central nervous system depressants such as alcohol and opiates, the potential for toxicity and fatal ...

*Ethyl formate

... and the respiratory system of humans and other animals; it is also a central nervous system depressant. In industry, it is used ... Department of Agriculture quarantine system) OSHA considers a time-weighted average of 100 parts per million (300 milligrams ...

*Diazepam

The impairment is worsened by consumption of alcohol, because both act as central nervous system depressants. During the course ... Concomitant use of other central nervous system depressants increases this risk. The smallest possible effective dose should be ... As a result, the arousal of the cortical and limbic systems in the central nervous system is reduced. The GABAA receptor is a ... Diazepam binding in mammalian central nervous system: a pharmacological characterization". The Journal of Neuroscience. 1 (2): ...

*Tizanidine

... has the potential to interact with other central nervous system depressants. Alcohol should be avoided, particularly ... or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a ... The CNS-depressant effects of tizanidine and alcohol are additive. It has a volume of distribution of 2.4 L/kg following ...

*Meclizine

It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Its antiemetic and antivertigo ... effects are not fully understood, but its central anticholinergic properties are partially responsible. The drug depresses ...

*Benzodiazepine

When combined with other central nervous system (CNS) depressants such as alcoholic drinks and opioids, the potential for ... Taking benzodiazepines with alcohol, opioids and other central nervous system depressants potentiates their action. This often ... and to a lesser extent the central nervous system. These peripheral receptors are not structurally related or coupled to GABAA ... Peripheral benzodiazepine receptors are present in peripheral nervous system tissues, glial cells, ...

*Baclofen

It is used as a central nervous system depressant and skeletal muscle relaxant. It is also used in topical creams to help with ... "Baclofen". The American Society of Health-System Pharmacists. Retrieved 2011-12-06. Leggio, L.; Garbutt, J. C.; Addolorato, G ... are designed to deliver the medication directly to the spinal fluid rather than going through the digestive and blood system ...

*Propene

... acts as a central nervous system depressant via allosteric agonism of the GABAA receptor. Excessive exposure may result ...

*Cyclobenzaprine

The potential harm is increased when central nervous system depressants and antidepressants are also used; deliberate overdose ... These substances may interact with cyclobenzaprine: Central nervous system depressants (e.g. alcohol, opioids, benzodiazepines ...

*Lorazepam

Sleep apnea - Sleep apnea may be worsened by lorazepam's central nervous system depressant effects. It may further reduce the ... may depress central nervous system respiratory drive and are contraindicated in severe respiratory failure. An example would be ... American Society of Health-System Pharmacists. June 29, 2016. Archived from the original on 5 June 2016. Retrieved 15 July 2016 ... Lorazepam's anticonvulsant and CNS depressant properties are useful for the treatment and prevention of alcohol withdrawal ...

*Pregabalin

In clinical studies, pregabalin showed a side effect profile similar to other central nervous system depressants. Adverse drug ... and central neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate benefit. Other first ...

*Effects of alcohol on memory

Alcohol acts as a general central nervous system depressant, but it also affects specific areas of the brain to a greater ... It is a volatile, flammable, colorless liquid that acts as a central nervous system depressant. Ethanol can impair different ... Since alcohol affects the central nervous system, it hinders semantic storage functioning by restricting the consolidation of ... has an inhibitory effect on neurotransmission in the central nervous system. GABAA receptor subtypes vary in their sensitivity ...

*Xylazine

Results from early human clinical studies confirmed that xylazine has several central nervous system depressant effects. ... which are physiological antagonists to central nervous system depressants. Combining yohimbine and 4-aminopyridine in an effort ... As an agonist, xylazine leads to a decrease in neurotransmission of norepinephrine and dopamine in the central nervous system. ... The sedative and analgesic effects of xylazine are related to central nervous system depression. Xylazine's muscle relaxant ...

*Hopantenic acid

... (homopantothenic acid), also known as N-pantoyl-GABA, is a central nervous system depressant. Formulated as the ...

*Nitrazolam

... benzodiazepines which have central nervous system depressant activity". Journal of Medicinal Chemistry. 14 (11): 1078-1081. doi ...

*Pergularia

... anti-infertility and central nervous system depressant activity. Species Pergularia adenophylla Schltr. & K. Schum. - Cameroon ...

*Orange Valley Regional Groundwater Superfund site

It is also a known central nervous system depressant and can dissolves fats from the skin, causing skin irritation. There is ... DCE targets the skin, liver, kidneys, lungs, and central nervous system, in which exposure can result in irritation of the skin ... and central nervous system depression. In the early 1980s, when the contamination was first discovered, the Orange Water ... humans by all routes of exposure and poses a potential human health hazard for noncancer toxicity to the central nervous system ...

*Ethyl acetate

Animal experiments have shown that, at very high concentrations, the ester has central nervous system depressant and lethal ... symptoms of central nervous system depression, secondary anemia and liver damage. In humans, concentrations of 400 ppm cause ...

*Pyrazolam

... benzodiazepines Which Have Central Nervous System Depressant Activity". J. Med. Chem. 14 (11): 1078-1081. doi:10.1021/ ...

*Drug Recognition Expert

There are seven categories of classifications a DRE is looking for, including; Central Nervous System depressants ( ...

*Talbutal

Barbiturates act as nonselective depressants of the central nervous system (CNS), capable of producing all levels of CNS mood ...