Marekov LN, Steinert PM (1998). "Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell ... "Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope ... "Attachment of vimentin filaments to desmosomal plaques in human meningiomal cells and arachnoidal tissue". The Journal of Cell ... Desmoplakin is a critical component of desmosome structures in cardiac muscle and epidermal cells, which function to maintain ...

... and CFTR in the human epidermis and epidermal appendages". Histochemistry and Cell Biology. 147 (6): 733-748. doi:10.1007/ ... "The human antimicrobial peptide dermcidin activates normal human keratinocytes". The British Journal of Dermatology. 160 (2): ... The epithelial cells are interposed by the myoepithelial cells. Myoepithelial cells support the secretory epithelial cells. The ... List of distinct cell types in the adult human body Neas, John F. "Development of the Integumentary System". In Martini, ...

"Differential regulation of karyopherin alpha 2 expression by TGF-beta1 and IFN-gamma in normal human epidermal keratinocytes: ... specifically decreased CD8-positive T cell and NK cell numbers and an increase in CD4-positive T cells. The mice also had an ... Collins FS, Rossant J, Wurst W (January 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. ... Cell. Biol. 19 (3): 1810-20. doi:10.1128/MCB.19.3.1810. PMC 83974. PMID 10022868. Chatterjee-Kishore M, van Den Akker F, Stark ...

1991). "Putative tyrosine kinases expressed in K-562 human leukemia cells". Proc. Natl. Acad. Sci. U.S.A. 87 (22): 8913-7. ... 1996). "Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer ... and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth ... Cell Biol. ENGLAND. 32 (5): 489-97. doi:10.1016/S1357-2725(99)00145-4. ISSN 1357-2725. PMID 10736564. Kan, M; Wu X; Wang F; ...

In human keratinocytes Gli2 activation upregulates a number of genes involved in cell cycle progression including E2F1, CCND1, ... "The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells". ... Studies have also shown that GLI2 plays a dual role as activator of keratinocyte proliferation and repressor of epidermal ... of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... Lee WP (January 1996). "Purification, cDNA cloning, and expression of human sorcin in vincristine-resistant HOB1 lymphoma cell ... "Isolation and molecular cloning of human sorcin a calcium-binding protein in vincristine-resistant HOB1 lymphoma cells". ... "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Research. 48 (21): 5927-32. PMID 2901906. " ...

... can distinguish human keratinocyte cells from their transient amplifying keratinocyte analogues. The identification of this ... This involved transplanting autologous epidermis flaps from epidermal stem cells that had been genetically corrected. She ... In 1990 Pellegrini established the first urethral stem cell cultures for humans, which could be used to regenerate the urethra ... Pellegrini, Graziella; De Luca, Michele (November 13, 2018). "Living with Keratinocytes". Stem Cell Reports. 11 (5): 1026-1033 ...

... inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes". Mol. ... heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells". Biochem. Pharmacol. 40 (4 ...

IL-33 is constitutively located in the nucleus of structural cells of humans and mice and has a helix-turn-helix domain ... "Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice". Journal of Dermatological Science. 85 ( ... mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells. IL-33 is a member of the IL-1 ... B cells, Th2 cells, eosinophils, basophils and mast cells. This protein is also thought to cause the itching that is associated ...

... and epidermal growth factor (EGF). Other treatments include implanting cultured keratinocytes into the wound to reepithelialize ... In older cells, stress response genes are overexpressed when the cell is not stressed, but when it is, the expression of these ... Research into hormones and wound healing has shown estrogen to speed wound healing in elderly humans and in animals that have ... The enzymes and ROS produced by neutrophils and other leukocytes damage cells and prevent cell proliferation and wound closure ...

2008). "Histidase expression in human epidermal keratinocytes: regulation by differentiation status and all-trans retinoic acid ... 1991). "Localization of histidase to human chromosome region 12q22→q24.1 and mouse chromosome region 10C2→D1". Cytogenet. Cell ... 2005). "Regulation by glucagon of the rat histidase gene promoter in cultured rat hepatocytes and human hepatoblastoma cells". ... Histidine ammonia-lyase (EC 4.3.1.3, histidase, histidinase) is an enzyme that in humans is encoded by the HAL gene. It ...

Desmosomes are involved in cell-cell adhesion, and are particularly important for the integrity of heart and skin tissue. ... Sun C, Wang L, Yang XX, Jiang YH, Guo XL (June 2019). "The aberrant expression or disruption of desmocollin2 in human diseases ... The '2' and '3' isoforms of desmocollin and desmoglein are expressed in the lower epidermal layers, and the '1' proteins and ... notably cardiomyocytes and keratinocytes. Genetic disorders associated with desmocollin gene mutations include Carvajal ...

"Role of NF-kappaB in constitutive expression of MAIL in epidermal keratinocytes". The Journal of Veterinary Medical Science. 69 ... NF-kappa-B inhibitor zeta (IκBζ) is a protein that in humans is encoded by the NFKBIZ gene. This gene is a member of the ... "Entrez Gene: NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta". Nogai H, Wenzel SS, ... IκBζ is required for expression of the SASP CCL2 (MCP1) cytokine, which recruits macrophages to remove cancer cells. The ...

AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction". Journal of Cerebral Blood ... "Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells". Proc. Natl. Acad. Sci. U.S.A. 112 (33 ... which irreversibly arrested proliferation of a fraction of keratinocytes. In older mice SOD2 deficiency delayed wound closure ... During ischemia reperfusion, ROS release substantially contribute to the cell damage and death via a direct effect on the cell ...

In the human forearm, about 1300 cells per cm2 per hour are shed. Stratum corneum protects the internal structures of the body ... Desquamation, the process of cell shedding from the surface of the stratum corneum, balances proliferating keratinocytes that ... Corneodesmosomes (modified desmosomes) facilitate cellular adhesion by linking adjacent cells within this epidermal layer. ... During cornification, the process whereby living keratinocytes are transformed into non-living corneocytes, the cell membrane ...

Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal ... TGF-α can be produced in macrophages, brain cells, and keratinocytes. TGF-α induces epithelial development. Considering that ... When TGF-α binds to EGFR it can initiate multiple cell proliferation events. Cell proliferation events that involve TGF-α bound ... of TGF-alpha in erythroblasts and eosinophilic precursor cells and of epidermal growth factor receptors in blastlike cells of ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... 1998). "SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex". Mol. Cell. ... 1997). "Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex". Cell. 89 (3): 357-64. doi ... a novel protein conserved between human and yeast, is a component of a histone deacetylase complex". Mol. Cell. 1 (7): 1021-31 ...

Niacinamide increases the biosynthesis of ceramides in human keratinocytes in vitro and improves the epidermal permeability ... In cells, nicotinamide is incorporated into NAD+ and nicotinamide adenine dinucleotide phosphate (NADP+). NAD+ and NADP+ are ... If humans ingest nicotinamide, it will likely undergo a series of reactions that transform it into NAD, which can then undergo ... However, the human body can produce NAD+ from the amino acid tryptophan and niacin without our ingestion of nicotinamide. NAD+ ...

... type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytes". ... seem to activate the signal cascade initiated by epidermal growth factor upon ligand binding. HPV16 E5 and HPV2 E5 have also ... Together with E6, E7 serves to prevent cell death (apoptosis) and promote cell cycle progression, thus priming the cell for ... This tethering to the cell's nuclear matrix ensures faithful distribution of viral genomes to each daughter cell after cell ...

The mutants also display increased epidermal hyperplasia upon induction with TPA. PPAR-delta is activated in the cell by ... PPAR-delta is highly expressed in many tissues, including colon, small intestine, liver and keratinocytes, as well as in heart ... Articles with short description, Short description is different from Wikidata, Genes on human chromosome 6, Wikipedia articles ... Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, epidermal cell proliferation ...

2002). "Human B cells become highly responsive to macrophage-inflammatory protein-3 alpha/CC chemokine ligand-20 after cellular ... 3 alpha/CCL20 by epidermal keratinocytes and its role in atopic dermatitis". Int. Immunol. 13 (1): 95-103. doi:10.1093/intimm/ ... 2000). "Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells". J. ... 2002). "BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially". Blood. 99 (6): 1913-1921 ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... flanking region of human cytokeratin 19 gene in human cholangiocarcinoma cell line". Journal of Hepatology. 35 (4): 504-11. doi ... 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of ... Kucharzik T, Lügering N, Schmid KW, Schmidt MA, Stoll R, Domschke W (January 1998). "Human intestinal M cells exhibit ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... 2001). "Molecular basis of T cell-mediated recognition of pancreatic cancer cells". Cancer Res. 61 (5): 2038-46. PMID 11280764 ... Kuninger DT, Izumi T, Papaconstantinou J, Mitra S (2002). "Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like ... 2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): ...

D'Souza SJ, Pajak A, Balazsi K, Dagnino L (Jun 2001). "Ca2+ and BMP-6 signaling regulate E2F during epidermal keratinocyte ... "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature ... The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target ... E2F5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ...

... immature skin cells) into mature epidermal cells. RA reduces the size and secretion of the sebaceous glands, and by doing so ... Keratinocytes of the epidermal layer of the skin produce and secrete antimicrobial peptides (AMPs). Production of AMPs resistin ... For humans, liver content can range from 20 to 30 μg/gram wet weight. Notoriously, polar bear liver is acutely toxic to humans ... Lymphocytes include natural killer cells, which function in innate immunity, T cells for adaptive cellular immunity and B cells ...

The Journal of Cell Biology. 174 (4): 547-556. doi:10.1083/jcb.200601030. PMC 2064260. PMID 16908670. ABCA7+protein,+human at ... transporters are expressed and regulated during terminal keratinocyte differentiation: a potential role for ABCA7 in epidermal ... ABCA7 human gene details in the UCSC Genome Browser. This article incorporates text from the United States National Library of ... ATP-binding cassette sub-family A member 7 is a protein that in humans is encoded by the ABCA7 gene. The protein encoded by ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... prokaryotic and archaebacterial cells". European Journal of Cell Biology. 62 (2): 248-258. PMID 7925483. Børglum AD, Flint T, ... In humans, it is encoded by the WARS gene. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and ... January 2002). "A human aminoacyl-tRNA synthetase as a regulator of angiogenesis". Proceedings of the National Academy of ...

Sonic hedgehog-expressing epidermal cells induce the condensation of cells in the mesoderm. The clusters of mesodermal cells ... Keratinocytes are the major cells, constituting 95% of the epidermis, while Merkel cells, melanocytes and Langerhans cells are ... in humans, the cells comprising the outermost 0.25-0.40 mm of the skin are "almost exclusively supplied by external oxygen", ... The basal layer is a stem cell layer and through asymmetrical divisions, becomes the source of skin cells throughout life. It ...

2008). "Expression of epiregulin, a novel epidermal growth factor ligand associated with prognosis in human oral squamous cell ... is an autocrine growth factor in normal human keratinocytes". J. Biol. Chem. 275 (8): 5748-53. doi:10.1074/jbc.275.8.5748. PMID ... 2007). "Human corneal epithelial cell proliferation by epiregulin and its cross-induction by other EGF family members". Mol. ... 2006). "PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination ...

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes". ... "APOBEC3 proteins mediate the clearance of foreign DNA from human cells". Nature Structural & Molecular Biology. 17 (2): 222-9. ... "APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells". Nucleic Acids Research. 34 (1): 89 ... or A3A is a gene of the APOBEC3 family found in humans, non-human primates, and some other mammals. It is a single-domain DNA ...