Indeed, ovotransferrin alone is toxic to cancer cells in-vitro. Its antioxidant and anti-inflammatory properties may also make ... Shang N, Wu J (March 2018). "Egg White Ovotransferrin Shows Osteogenic Activity in Osteoblast Cells". Journal of Agricultural ... Egg allergy "OVOTRANSFERRIN: The nutraceutical protein with antimicrobial, antioxidant and immunomodulatory properties". ... This family is also known for their role in cell maturation by transporting essential nutrients to developing embryos. ...
Vitamin E is an antioxidant, so may help prevent further cell degeneration in the affected muscles. However, vitamin E products ... This subsequently alters the cell by preventing the cell's enzymes from functioning and the myofilaments from contracting ... The cell membranes may then be damaged if the horse is forced to continue work, which allows muscle enzymes and myoglobin to ... This leads to the body building up a store of glycogen from converted carbohydrates in muscle cells. Glycogen is then depleted ...
These studies establish that ENaC is an important regulator of fluid level in the luminal side of cells with motile cilia in ... Hanukoglu I (2006). "Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 ... Yet, in the eccrine sweat glands, ENaC was localized on the apical cell membrane exposed to the duct of these sweat glands. ... As the steroidogenic tissues have very high levels of antioxidants, Israel suspected that the P450 systems may leak electrons ...
Watu A, Metussin N, Yasin HM, Usman A (2018). "The total antioxidant capacity and fluorescence imaging of selected plant leaves ... Janicke B. "Digital holographic microscopy video showing cell division of unlabeled JIMT-1 breast cancer cells". The Cell - an ... Ettinger A, Wittmann T (2014). "Fluorescence live cell imaging". Quantitative Imaging in Cell Biology. Methods in Cell Biology ... Live-cell imaging is the study of living cells using time-lapse microscopy. It is used by scientists to obtain a better ...
MAAs are effective antioxidant molecules and are able to stabilize free radicals within their ring structure. In addition to ... protecting cells from mutation via UV radiation and free radicals, MAAs are able to boost cellular tolerance to desiccation, ...
Reducing the anti-oxidant capability of healthy cells can reduce effects that would have been favorable. However ZnPP have been ... ZnPP suppression of heme oxygenase reduces cell viability of cancer cells and increases cytotoxicity in cancer cells. ZnPP ... The inhibition of heme oxygenase leads to an increase of reactive oxidative species in the cell which sensitizes the cells to ... Tumors from brain cancer, colon cancer, prostate cancer, renal cell cancer, oral squamous cell cancer, and leukemia all show a ...
A novel zinc compound (Zinc-monocysteine) enhances the antioxidant capacity of human retinal pigment epithelial cells. Curr Eye ... Evidence for a dual origin from the neural retina and hyalocytes". J. Cell Biol. 71 (1): 59-67. doi:10.1083/jcb.71.1.59. PMC ...
... exhibit potent antioxidant activity in a cell-based assay". J Agric Food Chem. 57 (21): 10181-6. doi:10.1021/jf9025794. PMID ... ameliorate TNF-α-induced inflammation and associated molecular markers in human aortic endothelial cells". Molecular Nutrition ...
Antioxidant 1 copper chaperone (ATOX1) is required to maintain Cu(I) copper homeostasis in the cell. It can bind and transport ... If Cu(I) levels in the cell environment are elevated, however, ATP7A moves to the cell membrane and eliminates excess Cu(I) ... in the cell, Cu(I) ions are all tightly bound) in the cell and provides certain enzymes with Cu(I) (e.g. peptidyl-α- ... copper-translocating P-type ATPase in polarized MDCK cells". Am J Physiol Cell Physiol. 287 (5): C1463-71. doi:10.1152/ajpcell. ...
This inhibits the antioxidant activity of glutathione, leading to reactive oxygen species (ROS) damaging cell components. Over ... In addition to liver cells, kidney cell expression involves expression of the gene for FAH. Kidney failure is a potential ... and SA in cells inhibits the breakdown of thiol derivatives, leading to post-translational modifications to the antioxidant ... The inability of cells to process tyrosine can lead to chronic liver damage ending in liver failure, as well as renal disease ...
Steroidogenic cells include a diverse array of antioxidant systems to cope with the radicals generated by the steroidogenic ... The system is also expressed at high levels in steroidogenic theca cells in the ovary, and Leydig cells in the testis. During ... In adrenal cortex cells from zona fasciculata, the expression of the mRNAs encoding all three P450scc proteins is induced by ... In each steroidogenic cell, the expression of the P450scc system proteins is regulated by the trophic hormonal system specific ...
... exhibit potent antioxidant activity in a cell-based assay". J Agric Food Chem. 57 (21): 10181-6. doi:10.1021/jf9025794. PMID ... Cerdá, Begoña; Tomás-Barberán, Francisco A.; Espín, Juan Carlos (2005). "Metabolism of Antioxidant and Chemopreventive ...
Gorski, David (3 October 2016). "Stemedica Cell Technologies: More stem cell hard sell, courtesy of the people who brought you ... Penta Water also claims to have commissioned UC Davis to continue this study into the hydration abilities and antioxidant ... "that human skin cells cultured in Penta water had significantly less damage from ultraviolet radiation than skin cells cultured ... Wagner, David (21 September 2016). "A Closer Look At A San Diego Stem Cell Company's Leadership". kpbs.org. KPBS. Archived from ...
Chakraborty, D., & Bhattacharyya, M. (2001). Antioxidant defense status of red blood cells of patients with β-thalassemia and E ...
... thereby promoting antioxidant-mediated cell defense and redox regulation. It also protects cells against dopamine induced ... Cell. 160 (1-2): 132-144. doi:10.1016/j.cell.2014.11.048. PMC 4297538. PMID 25542313. Fang H, Stone KP, Forney LA, Wanders D, ... 2009). "Codrugs linking L-dopa and sulfur-containing antioxidants: new pharmacological tools against Parkinson's disease". ... and the important antioxidant glutathione, methionine plays a critical role in the metabolism and health of many species, ...
The next critical idea came with the discovery of programmed cell death, a novel form of cell suicide. Originally observed as a ... The anti-oxidant system is underdeveloped with reduced capacity to inactivate hydrogen peroxide. Mild hypothermia helps prevent ... Ellis HM, Horvitz HR (March 1986). "Genetic control of programmed cell death in the nematode C. elegans". Cell. 44 (6): 817-829 ... Raff MC (April 1992). "Social controls on cell survival and cell death". Nature. 356 (6368): 397-400. Bibcode:1992Natur.356.. ...
Cell. 153 (7): 1461-74. doi:10.1016/j.cell.2013.05.037. PMC 3760148. PMID 23791177. Deng, Han-Xiang; Chen, Wenjie; Hong, Seong- ... This enzyme is a powerful antioxidant that protects the body from damage caused by superoxide, a toxic free radical generated ... Free radicals can cause damage to DNA and proteins within cells. To date, over 110 different mutations in SOD1 have been linked ... However, failed trials with anti-oxidants and methodological limitation limit the hypothesis. One proposed mechanism of ALS ...
Intact GGC, which was synthesised in their own laboratory, was shown to be taken up by cells, bypassing the rate-limiting step ... It is the most immediate precursor to the antioxidant glutathione. GGC is synthesized from L-glutamic acid and L-cysteine in ... GGC is also capable of being a powerful antioxidant in its own right. GGC synthesis for commercial use is exceedingly difficult ... Quintana-Cabrera, Ruben; Bolaños, Juan (2013-01-29). "Glutathione and γ-glutamylcysteine in the antioxidant and survival ...
This complex can translocate into the nuclei of cancerous cells, but not of healthy cells. When in cancer cells, this protein- ... The cysteine residues aid in glutathione synthesis which is an important antioxidant. Cancer: There has been extensive research ... "Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei". Experimental Cell ... March 1999). "Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells". The ...
... cervical cells, and vaginal epithelial cells. In these tissues, hemoglobin absorbs unneeded oxygen as an antioxidant, and ... Some nonerythroid cells (i.e., cells other than the red blood cell line) contain hemoglobin. In the brain, these include the A9 ... alveolar cells, lungs, retinal pigment epithelium, hepatocytes, mesangial cells of the kidney, endometrial cells, ... The hemoglobin-derived iron in these cells is not the cause of the post-mortem darkness of these cells (origin of the Latin ...
He is studying also antioxidant agents derived from natural products against Parkinson's disease. Another topic of his research ... and nanoparticles of barium titanate that can convert mechanical energy in an electric potential able to excite brain cells. ...
Loss of the AMPKα2 subunit in pancreatic β-cells and hypothalamic neurons decreases the sensitivity of these cells to changes ... AMPK also activates anti-oxidant defenses. Many biochemical adaptations of skeletal muscle that take place during a single bout ... August 2008). "AMPK and PPARdelta agonists are exercise mimetics". Cell. 134 (3): 405-15. doi:10.1016/j.cell.2008.06.051. PMC ... September 2018). "SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death". Cell Death & Disease. 9 (9): ...
... is found on many cells, including endothelial cells, smooth muscle, cells of the immune system[which?] from tissue such as lung ... The authors suggested that antioxidant therapy might help prevent the accumulation of AGEs and induced damage. In the end, ... Peripheral macrophage as well as liver sinusoidal endothelial cells and Kupffer cells have been implicated in this process, ... a central cell surface receptor for S100/calgranulin polypeptides". Cell. 97 (7): 889-901. doi:10.1016/S0092-8674(00)80801-6. ...
... and protection of cells from premature aging, antioxidant activity, antioxidant content and antioxidant properties, and ... Most food compounds listed as antioxidants - such as polyphenols common in colorful, edible plants - have antioxidant activity ... On the contrary, research indicates that although polyphenols are antioxidants in vitro, antioxidant effects in vivo are ... which have antioxidant capacity in vitro and so provide an artificial index of antioxidant strength - the ORAC measurement. ...
Some lines of investigation are focused on the application of D. radiodurans antioxidant systems in human cells to prevent ROS ... The cells stain Gram positive, although its cell envelope is unusual and is reminiscent of the cell walls of Gram negative ... when the cells themselves are irradiated. Michael Daly has suggested the bacterium uses manganese complexes as antioxidants to ... a process by which DNA derived from one cell can be taken up by another cell and integrated into the recipient genome by ...
When the cell is stressed with disease, enzymes are drawn into the cell to produce small amounts of hydrogen sulfide. This ... Antioxidants & Redox Signaling. 15 (2): 363-372. doi:10.1089/ars.2010.3781. PMC 3118817. PMID 21254839. Wallace, John L.; Wang ... It is becoming increasingly clear that H2S is an important mediator of a wide range of cell functions in health and in diseases ... Hydrogen sulfide is also known to increase the levels of glutathione which acts to reduce or disrupt ROS levels in cells. The ...
Nerve cells. Sensory cells appear between or sometimes on top of the muscle cells, and communicate via synapses (gaps across ... The animals produce large quantities of antioxidants to neutralize the excess oxygen. All cnidarians can regenerate, allowing ... The two main cell layers of cnidarians form epithelia that are mostly one cell thick, and are attached to a fibrous basement ... These "nettle cells" function as harpoons, since their payloads remain connected to the bodies of the cells by threads. Three ...
... (Erythrocyte apoptosis or Red blood cell programmed death) is a type of apoptosis that occurs in injured erythrocytes ... Antioxidants & Redox Signaling. 8 (7-8): 1183-1192. doi:10.1089/ars.2006.8.1183. ISSN 1523-0864. PMID 16910766. v t e (Articles ... Like apoptosis, eryptosis is characterized by cell shrinkage, membrane blebbing, activation of proteases, and ... G6PD deficiency Iron deficiency anemia Lead or mercury intoxication Lopinavir Malaria Ritonavir Sickle cell anemia Thalassemia ...
Cell Mol. Biol. 29 (2): 206-12. CiteSeerX 10.1.1.325.1962. doi:10.1165/rcmb.2002-0152OC. PMID 12626341. Xu Y, Szép S, Lu Z ( ... December 2009). "The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related ... It has been researched extensively for its capabilities as an alternative antibiotic as it is harmless to human body cells ... Rada B, Leto TL (2009). "Redox warfare between airway epithelial cells and Pseudomonas: Dual oxidase versus pyocyanin". Immunol ...
... is predicted to be localized to the cell nucleus. There is also a predicted bipartite nuclear localization signal. ... This methionine richness has been hypothesized to serve as a mitochondrial antioxidant. There are four verified ubiquitination ... Amplification of the C16orf78 gene has been linked to metabolically adaptive cancer cells. A duplication of the C16orf78 gene ... Schindeldecker, Mario; Moosmann, Bernd (10 April 2015). "Protein-borne methionine residues as structural antioxidants in ...