A white or black speck found at end of cell. There is a waved postmedial line excurved beyond cell. An irregularly sinuous ... Hindwings with medial and submarginal waved lines. Ventral side with black cell-spot. Many specimens have two waved line with ... Forewings with indistinct oblique antemedial dark line. ...
... the first immortalized human cell line and one of the most important cell lines in medical research. An immortalized cell line ... The cells from the cancerous sample eventually became known as the HeLa immortal cell line, a commonly used cell line in ... Lacks's was the first mass-produced human cell line." Squamous cell carcinoma is a cancer of the squamous cells, a type of ... "led to the first immortal cell line", but that distinction belongs to the L929 cell line, which was derived from mouse ...
The HighFive cell line was originally developed at BTI. The cell line and its virus-free sub-clones remain the sole property of ... The High Five cells have been used to produce the VLP-based HPV vaccine Cervarix. Ascribe Bioscience is a startup based on a ... including the BTI Mass Spectrometry Facility and the Plant Cell Imaging Center, are available to researchers from Cornell ...
As with other immortalized cell lines, H1299 cells can divide indefinitely. These cells have a homozygous partial deletion of ... H1299, also known as NCI-H1299 or CRL-5803, is a human non-small cell lung carcinoma cell line derived from the lymph node, ... "CRL-5803/NCI-H1299 cell line". LGC Promochem: Cell Biology Collection. American Type Culture Collection. Retrieved 2008-06-22. ... "NCI-Navy Medical Oncology Branch cell line supplement". J. Cell. Biochem. Suppl. 24: 1-291. 1996. PMID 8965489. "ATCC Advanced ...
Marklund SL (October 1984). "Extracellular superoxide dismutase in human tissues and human cell lines". The Journal of Clinical ... Marklund SL (February 1990). "Expression of extracellular superoxide dismutase by human cell lines". The Biochemical Journal. ... and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved ... "The expression of extracellular-superoxide dismutase is increased by lysophosphatidylcholine in human monocytic U937 cells". ...
... causes programmed cell death in melanoma cell lines. Vemurafenib interrupts the B-Raf/MEK step on the B-Raf/MEK/ERK ... Activates the ERK Pathway and Enhances Cell Migration and Proliferation of BRAF(WT) Melanoma Cells". Pigment Cell Melanoma Res ... "Hairy Cell Leukemia: Celebrating Progress?". HCLF Blog. July 29, 2022. Retrieved July 25, 2022. "Hairy Cell Leukemia with ... Cancer cells begin to overexpress cell surface protein PDGFRB, creating an alternative survival pathway. A second oncogene ...
"Modeling ATP-mediated endothelial cell elongation on line patterns". Biomechanics and Modeling in Mechanobiology. doi:10.1007/ ... Cell surface (cortical) actin remodeling is a cyclic (9-step) process where each step is directly responsive to a cell ... Actin Thomas P. Stossel; Gabriel Fenteany; John H. Hartwig (2006). "Cell surface actin remodeling" (PDF). Journal of Cell ... Rottner, Klemens; Stradal, Theresia E.B. (2011). "Actin dynamics and turnover in cell motility". Current Opinion in Cell ...
"Caffeine augments Alprazolam induced cytotoxicity in human cell lines". Toxicology in Vitro. 23 (6): 1100-1109. doi:10.1016/j. ... Influx of calcium through the membranes in muscle cells requires at least 250 μM of caffeine. Normally, other toxic effects of ... The introduction of such high doses of caffeine allows calcium to enter the muscle cell through the plasma membrane and ... At very high concentrations of about 1-2 mM, caffeine lowers the excitability threshold in muscle cells, leading to prolonged ...
Ebselen shows anti-HIV activity in infected cell lines. Phage display was used to identify peptides that bind the HIV-1 capsid ... May 2008). "A cell-penetrating helical peptide as a potential HIV-1 inhibitor". Journal of Molecular Biology. 378 (3): 565-580 ... The mechanism of HIV infection involves the transport and integration of the viral genome into the DNA of the host cell. This ... Upon entering the cytoplasm of a host cell, the capsid goes through an unfolding process that releases the viral RNA and ...
Cellosaurus entry for DAOY v t e (Human cell lines, All stub articles, Cell biology stubs). ... DAOY is a widely used human medulloblastoma cell line. It has epithelial morphology and was obtained from a 4-year-old ... Sep 2016). "Top-down proteomic characterization of DAOY medulloblastoma tumor cell line". EuPA Open Proteomics. 12: 13-21. doi: ... Srivastava VK, Nalbantoglu J (Oct 2008). "Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer ...
"MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines". PLOS ONE. 4 (8): e6677. doi: ... Zheng ZF, Su HF, Zou Y, Peng Z, Wu SX (March 2011). "[Expression profiles of microRNAs in radioresistant esophageal cell line ... with application to clear cell Renal Cell Carcinoma". BMC Systems Biology. 4: 51. doi:10.1186/1752-0509-4-51. PMC 2876063. PMID ... Yang Y, Li X, Yang Q, Wang X, Zhou Y, Jiang T, Ma Q, Wang YJ (July 2010). "The role of microRNA in human lung squamous cell ...
January 1998). "6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin". Clinical Cancer Research. 4 (1): 117-30. ... cancer cells and stromal cells can symbiotically recycle and maximize the use of nutrients. Hypoxic adaptation by cancer cells ... In addition to cell-autonomous changes that drive a cancer cell to proliferate and contribute to tumorigenesis, it has also ... doi:10.1016/j.cell.2011.02.013. PMID 21376230. Cairns RA, Harris IS, Mak TW (February 2011). "Regulation of cancer cell ...
Wadman, Meredith (2010-02-22). "NIH may allow stem-cell lines from younger embryos". Nature News. doi:10.1038/news.2010.85. ... Skirboll was the agency's lead on policy issues related to fetal tissue, cloning, and stem cell research. She was responsible ... "U.S. tweaks stem cell policy". Reuters. 2010-02-19. Retrieved 2016-08-06. NIH Office of Science Policy Recombinant DNA Advisory ... Holden, Constance (2010-02-19). "NIH Expands Definition of Human Embryonic Stem Cell". Science - AAAS. Retrieved 2017-12-05. " ...
Cellosaurus entry for HaCaT HaCaT cells (Human cell lines). ... Lehmann, Bodo (1 January 1997). "HaCaT Cell Line as a Model ... "Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line". The Journal of Cell Biology. 106 ... HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, widely used in scientific ... "Comparison of Primary Human Fibroblasts and Keratinocytes with Immortalized Cell Lines Regarding their Sensitivity to Sodium ...
This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to ... This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells ... May 2008). "TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells". Cancer Research. 68 ... on human chromosome 2p24 is differentially expressed between androgen-dependent and androgen-independent prostate cancer cells ...
... in human leukemia HL-60 cells, and malignant head and neck squamous cell carcinoma SCC25 and SCC9 cell lines. In contrast, ... epithelial tumors, such as breast, colon, small cell lung and renal cell carcinomas, as well as T-cell leukemia cells, were ... "Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells". Cancer Letters. 175 (1): 17-25. doi: ... On the human normal dermatoblast cell line, betulinic acid was one-half to one-fifth as toxic as doxorubicin. The ability of ...
... , in combination with nivolumab, is indicated for the first-line treatment of adults with metastatic non-small cell ... Nasser NJ, Gorenberg M, Agbarya A (November 2020). "First line Immunotherapy for Non-Small Cell Lung Cancer". Pharmaceuticals. ... It is undergoing[when?] clinical trials for the treatment of non-small cell lung carcinoma (NSCLC), small cell lung cancer ( ... The CTLs recognize the cancer cells by those antigens and destroy them. However, along with the antigens, the dendritic cells ...
A postmedial double waved line slightly excurved beyond cell. Traces of an irregular sub-marginal lines present, along with a ... Ventral side of forewings with basal two thirds white, with spot at end of cell. The moth flies from June to September ... Forewings with indistinct sub-basal and waved antemedial lines. There are traces of orbicular, reniform, and claviform spots. ...
When a dog is infected, the parasite can be found in the small intestinal epithelium which are the cells that line the cavity ... Isospora canis) monozoic cysts in two noncanine cell lines". Journal of Parasitology. 95 (4): 793-798. doi:10.1645/GE-1951.1. ... Gametes are part of the sexual stages, and they can invade other cells. Male gametes divide and break out to the host cell, ... then go invade cells containing the female gamete. Once the male gametes and the female gamete are in the same host cell, they ...
Kunze D, Fuessel S, Meye A, Wirth MP, Schmidt U (May 2006). "Functional analyses of C13orf19/P38IP in prostate cell lines". ... 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ... doi:10.1016/j.cell.2006.03.032. PMID 16713569. Zohn IE, Li Y, Skolnik EY, et al. (2006). "p38 and a p38-interacting protein are ... doi:10.1016/j.cell.2006.03.048. PMID 16751104. FactorBook SPT20 v t e (Articles with short description, Short description ...
Biochemical characterization and subcellular localization in different cell lines". The Journal of Biological Chemistry. 275 ( ... "S100A13 and S100A6 exhibit distinct translocation pathways in endothelial cells". Journal of Cell Science. 115 (Pt 15): 3149-58 ... In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting ... S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a ...
Hall A, Marshall CJ, Spurr NK, Weiss RA (1983). "Identification of transforming gene in two human sarcoma cell lines as a new ... cell differentiation, cell adhesion, apoptosis, and cell migration. Ras and Ras-related proteins are often deregulated in ... Reovirus was noted to be a potential cancer therapeutic when studies suggested it reproduces well in certain cancer cell lines ... Marshall CJ, Hall A, Weiss RA (September 1982). "A transforming gene present in human sarcoma cell lines". Nature. 299 (5879): ...
This cell line is also part of the NCI-60 cancer cell line panel used by the National Cancer Institute. Jørgen Fogh, Jens M. ... The SK-OV-3 cell line is also hypodiploid, with a modal number of chromosomes of 43 (range 42-45), occurring in 63.3% of cells ... SK-OV-3 (also known as SKOV-3; SK.OV.3; SKOV3; Skov3 and SKO3) is an ovarian cancer cell line derived from the ascites of a 64- ... Cellosaurus entry for SK-OV-3 (Human cell lines). ... One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines ...
ARK5 is often overexpressed in multiple myeloma cell lines. ARK5 promotes tumor cell survival under regulation by Akt. ARK5 ... also inhibits ARK5 and reduces proliferation of multiple myeloma and mantle cell lymphoma cell lines. NUAK1 has been shown to ... Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. ARK5 is important in tumor ... Cell. Biol. 24 (8): 3526-35. doi:10.1128/MCB.24.8.3526-3535.2004. PMC 381626. PMID 15060171. Multi-Target Drug Blocks Myeloma ...
Wang, Ying; Oberley, Larry W; Murhammer, David W (2001). "Antioxidant defense systems of two lipidopteran insect cell lines". ... "Evidence of oxidative stress following the viral infection of two lepidopteran insect cell lines". Free Radical Biology and ... Murhammer is an editor of Baculovirus and Insect Cell Expression Protocols. He has also made numerous presentations at ... Saarinen, Mark A.; Murhammer, David W. (13 November 2002). "The response of virally infected insect cells to dissolved oxygen ...
Ganguly A, Yang H, Cabral F (November 2010). "Paclitaxel-dependent cell lines reveal a novel drug activity". Mol. Cancer Ther. ... Early studies in cancer cell lines and human cancer patients indicate superior efficacy to the taxanes. Their mechanism of ... Microtubules are essential to cell division, and epothilones, therefore, stop cells from properly dividing. Epothilone B ... Finally, epothilone B also causes cell cycle arrest at the G2-M transition phase, thus leading to cytotoxicity and eventually ...
Armstrong, J. A.; Porterfield, J. S.; De Madrid, A. T. (1971). "C-type virus particles in pig kidney cell lines". The Journal ... stimulated by CD4+ T cells) and NK cells (stimulated by the release of Il-2). Thus, the role of MHC molecules and T cell ... where they coexist with the recipient's stem cells. The bone marrow stem cells give rise to cells of all hematopoietic lineages ... Lymphoid progenitor cells are created by this process and move to the thymus where negative selection eliminates T cells found ...
... they are thus within the line's unit cell segment. There are 2 one-dimensional line groups. They are the infinite limits of the ... These symmetries include repeating along that line, making that line a one-dimensional lattice. However, line groups may have ... A line group is a mathematical way of describing symmetries associated with moving along a line. ... "Line Groups Structure", Line Groups in Physics, Lecture Notes in Physics, vol. 801, Springer, pp. 7-27, doi:10.1007/978-3-642- ...
... cell crossed by three or four additional short lines; a postdiscal very incomplete series of white-centred broad fuscous rings ... the outer line broken and incomplete, followed by two irregular black lines, a subterminal more pronounced black line, and ... Hindwing with three transverse fine lines; a pair of postdiscal broad black lines shaded with light sepia brown between, ... In many specimens there is a diffuse fuscous spot between the discal pair of transverse fine lines on forewing. Antennae, head ...
Both wings with cell-speck. A medial oblique line excurved round cell of forewings. Sinuous postmedial and submarginal lines ... The submarginal dark line of the wing with white on its outer edge. Scopula adeptaria adeptaria Scopula adeptaria tenuipes ( ... Forewings with indistinct sinuous antemedial fuscous line excurved above median nervure. ...