Loading...
*  List of breast cancer cell lines
Cailleau R, Young R, Olivé M, Reeves WJ Jr (1974). "Breast tumor cell lines from pleural effusions". Journal of the National ... Lasfargues EY, Coutinho WG, Redfield ES (1978). "Isolation of two human tumor epithelial cell lines from solid breast ... 2006). "A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes". Cancer Cell. 10 (6): ... "Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery ...
*  Halichondrin B
"NCI-60 DTP Human Tumor Cell Line Screen". Developmental Therapeutics Program, National Cancer Institute. Archived from the ... "60-cell line screen" The complete chemical synthesis of halichondrin B was achieved by Yoshito Kishi and colleagues at Harvard ... these authors also reported the exquisite anticancer activity of halichondrin B against murine cancer cells both in culture and ...
*  DAOY (biology)
Sep 2003). "Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and ... Sep 2016). "Top-down proteomic characterization of DAOY medulloblastoma tumor cell line". EuPA Open Proteomics. 12: 13-21. ... DAOY is a widely used human primary medulloblastoma cell line. It has epithelial morphology and was obtained from a 4-year-old ... Srivastava VK, Nalbantoglu J (Oct 2008). "Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer ...
*  Tumor necrosis factor superfamily
It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, ... FASL, a cell surface protein involved in cell death. 4-1BBL, an inducible T cell surface molecule that contributes to T-cell ... two related cytokines produced by lymphocytes that are cytotoxic for a wide range of tumor cells in vitro and in vivo. T cell ... The tumor necrosis factor (TNF) superfamily refers to a superfamily of cytokines that can cause cell death (apoptosis). The ...
*  Interleukin 10
Expression of IL-10 from transfected tumor cell lines. in IL-10 transgenic mice. or dosing with IL-10 leads to control of ... mast cells, CD4+CD25+Foxp3+ regulatory T cells, and in a certain subset of activated T cells and B cells. IL-10 can be produced ... In melanoma cell lines, IL-10 modules the surface expression of NKG2D ligands. Knockout studies in mice suggested the function ... it is also stimulatory towards certain T cells (Th2) and mast cells and stimulates B cell maturation and antibody production. ...
*  Myeloid-derived suppressor cell
Tumor cell lines overexpressing colony stimulating factors (e.g. G-CSF and GM-CSF) have long been used in in vivo models of ... Similar to other myeloid cells, MDSCs interact with other immune cell types including T cells, dendritic cells, macrophages and ... These MDSCs infiltrate inflammation sites and tumors, where they stop immune responses by inhibiting T cells and NK cells, for ... MDSC (myeloid-derived suppressor cells) are a heterogenous group of immune cells from the myeloid lineage (a family of cells ...
*  BARD1
"Genetic analysis of BRCA1 function in a defined tumor cell line". Molecular Cell. 4 (6): 1093-9. doi:10.1016/S1097-2765(00) ... "Genetic analysis of BRCA1 function in a defined tumor cell line". Molecular Cell. 4 (6): 1093-9. doi:10.1016/S1097-2765(00) ... Inhibiting cancer cells' BRCA1/BARD1 heterodimer from relocating to DNA damage sites would induce tumor cell death rather than ... Jin Y, Xu XL, Yang MC, Wei F, Ayi TC, Bowcock AM, Baer R (Oct 1997). "Cell cycle-dependent colocalization of BARD1 and BRCA1 ...
*  TUSC3
Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been ... Tumor suppressor candidate 3 is a protein that in humans is encoded by the TUSC3 gene. This gene is a candidate tumor ... "Entrez Gene: TUSC3 tumor suppressor candidate 3". Pak BJ, Park H, Chang ER, et al. (1998). "Differential display analysis of ... Cell. 12 (1): 101-11. doi:10.1016/S1097-2765(03)00243-0. PMID 12887896. Anderson NL, Polanski M, Pieper R, et al. (2004). "The ...
*  Kendomycin
It also has strong cytotoxicity against various tumor cell lines. Because of its potent biological activities, kendomcyin has ...
*  Capillin
Whelan LC, Ryan MF (2004). "Effects of the polyacetylene capillin on human tumour cell lines". Anticancer Research. 24 (4): ... Capillin exhibits cytotoxic activity and could cause apoptosis of certain human tumor cells. "Showing metabocard for Capillin ( ...
*  CCL7
It is produced by certain tumor cell lines and by macrophages. This chemokine is located on chromosome 17 in humans, in a large ... Van Damme J, Proost P, Lenaerts JP, Opdenakker G (1992). "Structural and functional identification of two human, tumor-derived ... 1999). "Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling". J. ... 1997). "Expression of monocyte chemotactic protein-3 in human monocytes and endothelial cells". Eur. Cytokine Netw. 8 (3): 271- ...
*  YPEL3
... near the promoters of tumor suppressor genes have been documented in specific tumor cell lines. In the case of the tumor ... In both human normal and tumor cell lines, YPEL3 has been shown to be a p53-inducible gene. Two putative p53 binding sites have ... YPEL3 has growth inhibitory effects in normal and tumor cell lines. One of five family members (YPEL1-5), YPEL3 was named in ... Campisi J (2005). "Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors". Cell. 120 (4): 513- ...
*  RABGEF1
"Seven genes that are differentially transcribed in colorectal tumor cell lines". Cancer Lett. 160 (1): 37-43. doi:10.1016/S0304 ... Cell. 118 (5): 607-17. doi:10.1016/j.cell.2004.08.009. PMID 15339665. Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The ... doi:10.1016/j.cell.2006.02.020. PMID 16499958. Kalesnikoff J, Rios EJ, Chen CC, et al. (2007). "Roles of RabGEF1/Rabex-5 ... Cell. 12 (7): 2219-28. doi:10.1091/mbc.12.7.2219. PMC 55678 . PMID 11452015. de Renzis S, Sönnichsen B, Zerial M (2002). " ...
*  Eugene O. Major
Major, E. O. (1983). "JC virus T protein expression in owl monkey tumor cell lines". Progress in clinical and biological ... Molinaro, G. A.; Major, E. O.; Bernhardt, G.; Dray, S.; Di Mayorca, G. (1977). "Similar cell surface antigens on hamster cells ... Major, E. O.; Di Mayorca, G. (1973). "Malignant Transformation of BHK21 Clone 13 Cells by BK Virus-A Human Papovavirus". ... Major, E. O.; Matsumura, P. (1984). "Human embryonic kidney cells: stable transformation with an origin-defective simian virus ...
*  TMPRSS2
"Mutation analyses of 268 candidate genes in human tumor cell lines". Genomics. 74 (3): 352-64. doi:10.1006/geno.2001.6551. PMID ... This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen- ... The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. The biological ... Cancer Cell. 17 (5): 443-54. doi:10.1016/j.ccr.2010.03.018. PMC 2874722 . PMID 20478527. Maruyama K, Sugano S (Jan 1994). " ...
*  Pituicytoma
"A human pituitary tumor-derived folliculo-stellate cell line". J Clin Endocrinol Metab. 85: 1180-1187. doi:10.1210/jc.85.3.1180 ... This tumor is thought to be derived from the parenchymal cells of the posterior lobe of the pituitary gland, called pituicytes ... Some researchers believe that they arise from the folliculostellate cells in the anterior lobe of the pituitary. As such, it is ... Inoue K, Couch EF, Takano K, Ogawa S (1999). "The structure and function of folliculo-stellate cells in the anterior pituitary ...
*  Annexin A4
"Expression of carbohydrate-binding protein p33/41 in human tumor cell lines". Journal of Biochemistry. 119 (2): 346-53. doi: ... "Modulation of paclitaxel resistance by annexin IV in human cancer cell lines". British Journal of Cancer. 83 (1): 83-8. doi: ... ANX4 is almost exclusively expressed in epithelial cells. GRCh38: Ensembl release 89: ENSG00000196975 - Ensembl, May 2017 ... Histochemistry and Cell Biology. 110 (2): 137-48. doi:10.1007/s004180050275. PMID 9720986. Chow A, Davis AJ, Gawler DJ (Mar ...
*  EPS8
"Constitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformation". Mol. Cell. Biol. 15 (7): 3805 ... "Constitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformation". Mol. Cell. Biol. 15 (7): 3805 ... Cell. 15 (1): 91-8. doi:10.1091/mbc.E03-06-0427. PMC 307530 . PMID 14565974. Biesova Z, Piccoli C, Wong WT (January 1997). " ... Cell Biol. 34 (10): 1178-83. doi:10.1016/S1357-2725(02)00064-X. PMID 12127568. Cardwell C (1977). "Student or worker? ...
*  BIN1
Aberrant splice variants expressed in tumor cell lines have also been described. In humans, mutations in BIN1 have been ... "A Role for the Putative Tumor Suppressor Bin1 in Muscle Cell Differentiation". Mol. Cell. Biol. 18 (1): 566-75. PMC 121524 . ... Cell. 8 (10): 2003-15. doi:10.1091/mbc.8.10.2003. PMC 25662 . PMID 9348539. Kadlec L, Pendergast AM (1997). "The amphiphysin- ... Cell Biol. 137 (6): 1355-67. doi:10.1083/jcb.137.6.1355. PMC 2132527 . PMID 9182667. Ramjaun AR, Micheva KD, Bouchelet I, ...
*  BRCA1
"Genetic analysis of BRCA1 function in a defined tumor cell line". Mol. Cell. 4 (6): 1093-9. doi:10.1016/S1097-2765(00)80238-5. ... "Isolation of two human tumor epithelial cell lines from solid breast carcinomas". Nat. Genet. 11: 198-200. doi:10.1038/ng1095- ... "Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells". Mol. Cell ... In breast cancer cell lines, there is an inverse correlation of BRCA1 protein levels with miR-182 expression. Thus it appears ...
*  DNA polymerase beta
"DNA polymerase beta expression differences in selected human tumors and cell lines". Carcinogenesis. 20 (6): 1049-54. doi: ... Collins FS, Rossant J, Wurst W (Jan 2007). "A mouse for all reasons". Cell. 128 (1): 9-13. doi:10.1016/j.cell.2006.12.018. PMID ... "Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor ... Cell. 154 (2): 452-64. doi:10.1016/j.cell.2013.06.022. PMC 3717207 . PMID 23870131. "Infection and Immunity Immunophenotyping ( ...
*  Coxsackie virus and adenovirus receptor
Moreover, CAR expression is not found in normal or tumor cell lines. Expression of CAR in endothelial cells can be regulated by ... This was coordinate with the loss of connexin-45 at cell-cell junctions on the sarcolemmal membranes of AV node cells. Mice ... in cell adhesion and growth". Journal of Cell Science. 117 (Pt 19): 4401-9. doi:10.1242/jcs.01300. PMID 15304526. Funke C, Farr ... CAR protein is expressed in several tissues, including heart, brain, and, more generally, epithelial and endothelial cells. In ...
*  PDGFC
Zwerner JP, May WA (2002). "Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines". Oncogene. 21 (24): 3847 ... "Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines". Exp. Cell Res. 312 (6): 782- ... Cell Biol. 2 (5): 302-9. doi:10.1038/35010579. PMID 10806482. Ding H, Wu X, Boström H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh ... Cell Biol. 2 (5): 302-9. doi:10.1038/35010579. PMID 10806482. Tsai YJ, Lee RK, Lin SP, Chen YH (2000). "Identification of a ...
*  ST7
Brown VL, Proby CM, Barnes DM, Kelsell DP (July 2002). "Lack of mutations within ST7 gene in tumour-derived cell lines and ... Sivasundaram K, Suzuki H, Seto M, Hosokawa Y (2004). "Mutational analysis of the ST7 gene in human myeloid tumor cell lines". ... "Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1". ... Vincent JB, Petek E, Thevarkunnel S, Kolozsvari D, Cheung J, Patel M, Scherer SW (September 2002). "The RAY1/ST7 tumor- ...
*  PTENP1
1998). "MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines". Cancer Res. 57 (23): 5221-5. PMID 9393738. ... 1998). "Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell ... lines". Oncogene. 16 (1): 89-93. doi:10.1038/sj.onc.1201512. PMID 9467947. Dahia PL, FitzGerald MG, Zhang X, et al. (1998). "A ...
*  Phage display
The use of a helper phage can be eliminated by using 'bacterial packaging cell line' technology. Elution can be done combining ... The technique is also used to determine tumour antigens (for use in diagnosis and therapeutic targeting) and in searching for ... Then the expression of single chain Fv's (scFv), and single chain T cell receptors (scTCR) were expressed both with and without ... Endemann H, Model P (July 1995). "Location of filamentous phage minor coat proteins in phage and in infected cells". J. Mol. ...