Fusion occurs when the virus fuses together with the target cell membrane and releases its genome into the cell. RSV enters the ... The function of env is to bind RSV to the host cell receptor and induce fusion with the target cell in a pH independent manner ... There are two ways viruses can enter the host cell: cell receptor endocytosis or fusion. Endocytosis is the process where the ... Gilbert JM, Mason D, White JM (October 1990). "Fusion of Rous sarcoma virus with host cells does not require exposure to low pH ...
"Uniquantal release through a dynamic fusion pore is a candidate mechanism of hair cell exocytosis". Neuron. 83 (6): 1389-403. ... Postsynaptic structures differ for cochlear cells and photoreceptor cells. Hair cells is capable of one action potential ... Wichmann, C; Moser, T (July 2015). "Relating structure and function of inner hair cell ribbon synapses". Cell and Tissue ... Information is conveyed from photoreceptor cells to bipolar cells via the release of the neurotransmitter glutamate at the ...
VP22 fusion protein upregulates interferon-beta in prostate cancer cell line PC-3". DNA Cell Biol. 25 (9): 523-9. doi:10.1089/ ... and to decrease invasive potential of human prostate cancer cell line (PC-3 cells). It is now believed to be a chaperon ... Liu X, Daskal I, Kwok SC (2003). "Effects of PTX1 expression on growth and tumorigenicity of the prostate cancer cell line PC-3 ... Kwok SC, Kumar S, Dai G (2014). "Characterization of a variant ERGIC2 transcript". DNA Cell Biol. 33 (2): 73-78. doi:10.1089/ ...
Malvoisin E, Wild F (August 1997). "Inhibition of HIV-1, HIV-2 and SIV envelope glycoprotein-mediated cell fusion by calmodulin ... Zhang M, Yuan T (1998). "Molecular mechanisms of calmodulin's functional versatility". Biochemistry and Cell Biology. 76 (2-3 ... Cell Calcium. 23 (5): 323-338. doi:10.1016/S0143-4160(98)90028-8. PMID 9681195. v t e (Articles with short description, Short ... Molecular Biology of the Cell. 13 (9): 3235-3245. doi:10.1091/mbc.E02-02-0112. PMC 124155. PMID 12221128. Berchtold MW, Egli R ...
April 2017). "Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia". Scientific ... the nucleus is enlarged because this is a B-cell lymphoma cell. The two proteins of interest are a B cell receptor and MYD88. ... The finding of interaction in the cytoplasm was interesting because B cell receptors are thought of as being located in the ... Kwon J, Jeong SM, Choi I, Kim NH (2016). "ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development". ...
... is a recombinant fusion protein designed to inhibit B cells, thereby suppressing autoimmune disease. The designer ... Atacicept is thought to selectively impair mature B cells and plasma cells with less impact on progenitor cells and memory B ... The drug is also being studied for treatment of B-cell malignancies, including multiple myeloma, B-cell chronic lymphocytic ... Atacicept blocks activation of B cells by the tumor necrosis factor receptor superfamily member 13B (more commonly known as ...
"Molecular dissection of the mechanisms of cell-cell fusion in the fission yeast". cordis.europea.eu. "The mechanisms of cell- ... Martin was awarded a European Research Council Consolidator Grant to study cellular fusion. The fusion of cells is critical in ... Such fusion requires communication between cells, followed by polarisation, self-assembly and membrane juxtaposition. Her ERC ... Martin studies the communication between cells and the mechanisms that underpin actin fusion focus formation.[citation needed] ...
"Evidence that extravillous trophoblast fusion into multinuclear trophoblast giant cells involves a mesenchymal-epithelial ... Apoptosis is a controlled cell death process that must not occur if a cell is to proliferate. PIF has specific anti-apoptotic ... Integrins are a broad class of cell adhesion molecules that allow cells to bind to extracellular matrix. In this way, they ... orchestrates systemic antiinflammatory response by immune cells: effect on peripheral blood mononuclear cells". American ...
... revealing the molecular mechanism of secretion and membrane fusion in cells". J. Cell. Mol. Med. 8 (1): 1-21. doi:10.1111/j. ... The transient fusion of secretory vesicle membrane at a porosome, base via SNARE proteins, results in the formation of a fusion ... Porosomes vary in size depending on the cell type. Porosome in the exocrine pancreas and in endocrine and neuroendocrine cells ... structures in the cell membranes of eukaryotic cells where secretory vesicles transiently dock in the process of vesicle fusion ...
"Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion". Cell. 83 (3): 423-32. doi:10.1016/0092- ... "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion". Cell. 83 (3): 423-32. doi:10.1016/0092- ... The Journal of Cell Biology. 151 (3): 601-12. doi:10.1083/jcb.151.3.601. PMC 2185588. PMID 11062261. Bucci C, Parton RG, Mather ... Cell. 70 (5): 715-28. doi:10.1016/0092-8674(92)90306-W. PMID 1516130. Zahraoui A, Touchot N, Chardin P, Tavitian A (Jul 1989 ...
The extra energy is used to overcome the activation barrier of the fusion to the cell membrane. The virus protein (or part of ... "A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance". Scientific ... Pre-fusion proteins (or subunits) from the following viruses have been stabilised in experiments by the molecular clamp ... On a virus, pre-fusion proteins on their surface provide an attractive target for an immune reaction. However, if these ...
2004). "Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells". J. Cell Sci. 116 (Pt ... Legros F, Lombès A, Frachon P, Rojo M (2003). "Mitochondrial Fusion in Human Cells Is Efficient, Requires the Inner Membrane ... Cell. 13 (12): 4343-54. doi:10.1091/mbc.E02-06-0330. PMC 138638. PMID 12475957. Strausberg RL, Feingold EA, Grouse LH, et al. ( ... The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the ...
... usually on successive cells, with 2 sterile groups and a 4-celled carpogonial branch. Carposporophyte with a basal fusion cell ... where each cell contains 4 pericentral cells (2 lateral cells cut off first followed by 2 transverse pericentral cells), ... The lateral pericentral cells develop wings 1-2 mm broad. The upper (adaxial) transverse pericentral cells each produce a ... from cortical cells also in C. multifida), with cover cells on each side of the blade dividing to form a continuous cortical ...
Chang D.C. (1989) Cell Fusion and Cell Poration by Pulsed Radio-Frequency Electric Fields. In: Neumann E., Sowers A.E., Jordan ... 9 (4). "Method of and apparatus for cell poration and cell fusion using radio frequency electrical pulses". United States ... They found that for breast tissue cells evolving from normal cells to pre-tumor cell (pre-neoplastic) and finally to tumor ... "Dynamic redistribution of calmodulin in HeLa cells during cell division as revealed by a GFP-calmodulin fusion protein ...
The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices. Biomaterials 33(29):6943. ... Although muscle contains a stem cell population called satellite cells that are capable of regenerating small muscle injuries, ... Muscle tissue engineering is a subset of the general field of tissue engineering, which studies the combined use of cells and ... It has been shown that cells grown on substrates with alignment cues form more robust muscle fibers. Several other design ...
HIV infects T cells that carry the CD4 antigen on their surface. When HIV infects its target cell it requires fusion of the ... This fusion creates a pore through which the viral capsid enters the cell. Following entry into the cell the RNA of the virus ... The virions bud from the cell and are released to infect other cells. All infected cells are eventually killed because of this ... The viral DNA enters the nucleus where it is integrated into the genetic material of the cell by the integrase, a second ...
The extremely favorable conditions of germination in Africa caused a fusion of these life cells. So the uniting of kindred ... The electrical vibrations of the Hooey Hound cell and the foreign cell were the same. They were kindred cells. In fact, all ... A number of Jeep life cells were somehow forced through the dimensional barrier into our world. They combined at a favorable ... cells caused a transmutation. The result, a mysterious strange animal. When asked if he had any further questions, Popeye, ...
β-galactosidase activity of a PsuhB::lacZ fusion confirmed the lower expression of suhB in TFA cells growing at low rates. A ... suhB has been detected as a 61 nt long sRNA by Northern blot in TFA cells growing at high rates. ...
... and showed that inhibition of tumor cells bearing ROS1 gene fusions by crizotinib or other ROS1 tyrosine kinase inhibitors was ... Although the most preclinical and clinical studies of ROS1 gene fusions have been performed in lung cancer, ROS1 fusions have ... "Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion". ... "Identifying and targeting ROS1 gene fusions in non-small cell lung cancer". Clinical Cancer Research. 18 (17): 4570-9. doi: ...
The cell fusions provide the matrix for the regeneration of bone tissue. Maërl is also used as a food additive for cattle and ... The calcite crystals composing the cell wall are elongated perpendicular to the cell wall. The calcite normally contains ... They are characterized by a thallus that is hard because of calcareous deposits contained within the cell walls. The colors of ... Some corallines slough off a surface layer of epithallial cells, which in a few cases may be an antifouling mechanism which ...
After fusion of the cells, the further fusion of their nuclei is delayed. Instead, a nucleus from the fertilizing cell and a ... Next the two uninucleate cells on either side of the first ascus-forming cell fuse with each other to form a binucleate cell ... The second reason is that haploid cells of one mating type, upon cell division, often produce cells of the opposite mating type ... Such contact can be followed by cell fusion leading to one or more nuclei from the fertilizing cell migrating down the ...
Cell. Mol. Biol. Lett. 9 (4A): 739-53. PMID 15647795. Dong S, Dong C, Liu L, et al. (2003). "Identification of a novel human ... vacuole fusion in yeasts and lysosome one motility in mammals and other taxa. In humans has been described an interaction with ...
Nuclear Fusion. 56 (1): 014001. arXiv:1503.08334. Bibcode:2016NucFu..56a4001Q. doi:10.1088/0029-5515/56/1/014001. S2CID ... ISBN 0-85274-392-0. Particle-In-Cell and Kinetic Simulation Software Center (PICKSC), UCLA. Open source 3D Particle-In-Cell ... Perhaps the easiest and most used choice for the shape function is the so-called cloud-in-cell (CIC) scheme, which is a first ... "PIConGPU - Particle-in-Cell Simulations for the Exascale Era - Helmholtz-Zentrum Dresden-Rossendorf, HZDR". picongpu.hzdr.de. ...
... and proliferation of their parent cells. The tyrosine kinase of the ETV6-NTRK3 fusion protein is dysfunctional in that it is ... "Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma". Cancer Cell. 2 (5): 367-76. ... "The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells". Oncogene. 19 (7): 906-15. ... and proliferation of their parent cells. In consequence, these cells take on malignant characteristics and are on the pathway ...
"Matrix Protein 2 of Influenza a Virus Blocks Autophagosome Fusion with Lysosomes". Cell Host & Microbe. 6 (4): 367-380. doi: ... "The functional impairment of natural killer cells during influenza virus infection". Immunology and Cell Biology. 87 (8): 579- ... Cell Host & Microbe. 2 (6): 404-416. doi:10.1016/j.chom.2007.09.014. PMC 2184509. PMID 18078692. Vigil, A.; Park, M. -S.; ... "Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation". Journal ...
September 2004). "Control of vesicle fusion by a tyrosine phosphatase". Nature Cell Biology. 6 (9): 831-9. doi:10.1038/ncb1164 ... SNAREs play a vital role in the trafficking of cell cargo. The vesicles fuse to the cell membrane with the help of SNARE ... It is a vital aid to exporting and importing cell cargo through a process called cell trafficking. Its SNARE motif shows ... This links the cell membrane and vesicles together in such a way that it overcomes the energetic barrier to fusing two lipid ...
Colman, P. M.; Lawrence, M. C. (2003). "The structural biology of type I viral membrane fusion". Nature Reviews Molecular Cell ... Colman's research interests are in structural biology, especially of human B-cell lymphoma 2 (BCL-2). Colman determined the ... Molecular Cell. 17 (3): 393-403. doi:10.1016/j.molcel.2004.12.030. PMID 15694340. Anon (2014). "Professor Peter Colman FRS". ... an essential step in the intrinsic cell-death pathway. His work has been published in leading peer reviewed scientific journals ...
For cell attachment and membrane fusion to occur, one or more viral envelope glycoproteins are required. In contrast to ... Although E2 participates in cell attachment, it is not yet known which protein causes membrane fusion. The bovine viral ... Additionally, when the BVDV virus infects a cell, the cell chaperone DNAJC14 joins forces with the viral NS2-NS3 to facilitate ... The most important structural protein is E2, which regulates cell tropism by interacting with cell surface receptors and ...
The zygospore is formed by the fusion of gametangial cells or the scalariform fusion of hyphae. Little is known about the ...
After fertilization and development of connecting filaments and fusion with intercalary vegetative cells, a carposporphyte ... It is bright red and grows to 6 mm in diameter and composed of a single basal layer of cells which produce erect filaments some ... Rose pink in colour, the blades are composed of a filamentous axis bearing whorls of branchlets, four or five per axial cell. ...
Constantinescu S (2004). "Stemness, fusion and renewal of hematopoietic and embryonic stem cells". Journal of Cellular and ... "Core transcriptional regulatory circuitry in human embryonic stem cells". Cell. 122 (6): 947-56. doi:10.1016/j.cell.2005.08.020 ... These cells offer an important area of study because of their ability to maintain pluripotency. In other words, these cells ... ISBN 978-1-59102-564-1. Cavaleri F, Schöler HR (May 2003). "Nanog: a new recruit to the embryonic stem cell orchestra". Cell. ...
It is also able to initiate host cell fusion that results in multinucleated giant cells (MNGCs). The consequence of MNGCs has ... It leaves the vacuoles early, which allows for efficient replication of the bacteria inside the cell. Leaving the cell early ... mallei is able to survive inside host cells through its capabilities in disrupting the bacteria-killing functions of the cell. ... T cells (nitric oxide) are actually more involved in combating B. mallei in the later stages of its infection of a host. ...